Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 25 Researches
7.3
USERS' SCORE
Moderately Good
Based on 5 Reviews
7.8
Supplement Facts
Serving Size: 1 Lozenge
Amount Per Serving
%DV
Folate
167 mcg DFE(100 mcg folic acid)
42%
Vitamin B-12 (as Cyanocobalamin)
1 mg (1,000 mcg)
41,667%
Top Medical Research Studies
9
We explored the cost-effectiveness of different folic acid supplementation strategies aimed at preventing strokes in hypertensive individuals in China. By examining four policy options, we aimed to find the best approach to support stroke prevention while considering potential complications from undetected vitamin B12 deficiencies.
The policies varied from simply not addressing folate levels to providing targeted folate supplements after screening for B12 deficiencies. Our analysis, based on a five-year intervention modeled from the China Stroke Primary Prevention Trial, found that the most effective strategy combined folate supplementation with screening for both folate and B12 deficiencies.
This combination not only helped prevent strokes but also ensured that those with B12 deficiency received appropriate treatment. The implications of this research suggest that adopting integrated screening approaches could greatly enhance public nutrition strategies, ultimately saving costs and improving health outcomes for at-risk populations.
The policies varied from simply not addressing folate levels to providing targeted folate supplements after screening for B12 deficiencies. Our analysis, based on a five-year intervention modeled from the China Stroke Primary Prevention Trial, found that the most effective strategy combined folate supplementation with screening for both folate and B12 deficiencies.
This combination not only helped prevent strokes but also ensured that those with B12 deficiency received appropriate treatment. The implications of this research suggest that adopting integrated screening approaches could greatly enhance public nutrition strategies, ultimately saving costs and improving health outcomes for at-risk populations.
Read More
9
We explored the impact of folic acid supplementation on stroke prevention through an extensive look at 21 randomized clinical trials from around the world. This analysis involved over 115,000 participants, providing a comprehensive picture of how folate might influence stroke risk.
The findings revealed a noteworthy 10% reduction in stroke risk for those taking folic acid, suggesting that this vitamin plays a beneficial role in safeguarding against strokes. Interestingly, the effectiveness varied depending on whether the participants lived in areas where grains were fortified with folate. We observed a more significant impact in regions without fortified grains, highlighting that the local dietary context matters.
Furthermore, our analysis indicated that individuals without a prior history of stroke or heart issues experienced the most benefits from folic acid. These results emphasize the importance of individualized approaches to stroke prevention, considering both diet and personal health history. Overall, this substantial collection of trials supports the notion that folic acid could be a valuable component in stroke prevention strategies.
The findings revealed a noteworthy 10% reduction in stroke risk for those taking folic acid, suggesting that this vitamin plays a beneficial role in safeguarding against strokes. Interestingly, the effectiveness varied depending on whether the participants lived in areas where grains were fortified with folate. We observed a more significant impact in regions without fortified grains, highlighting that the local dietary context matters.
Furthermore, our analysis indicated that individuals without a prior history of stroke or heart issues experienced the most benefits from folic acid. These results emphasize the importance of individualized approaches to stroke prevention, considering both diet and personal health history. Overall, this substantial collection of trials supports the notion that folic acid could be a valuable component in stroke prevention strategies.
Read More
9
We explored the impact of tetrahydrofolate (THF) on cognitive impairment resulting from intracerebral hemorrhage (ICH), a common type of hemorrhagic stroke. This research is particularly important because ICH can lead to cognitive challenges and significant psychological burdens for patients.
Our findings revealed that administering THF helps restore cognitive function after ICH. By using specially designed Nestin-GFP mice, we observed that THF not only spurs the growth of neural stem cells in the hippocampus but also promotes the creation of new neurons. This enhancement in neurogenesis is crucial for cognitive health.
On a mechanistic level, we discovered that THF reduces elevated levels of the protein PTEN, which is known to inhibit cell growth, while simultaneously increasing the levels of phosphorylated AKT and mTOR—proteins essential for cell survival and growth. Additionally, by conditionally removing PTEN from hippocampal neural stem cells, we noticed a reduction in the negative effects ICH typically has on the proliferation of these cells and on neurogenesis.
Overall, our study sheds light on the potential of THF as a therapeutic option for those recovering from hemorrhagic strokes, providing valuable insights into how we might help improve recovery for affected individuals.
Our findings revealed that administering THF helps restore cognitive function after ICH. By using specially designed Nestin-GFP mice, we observed that THF not only spurs the growth of neural stem cells in the hippocampus but also promotes the creation of new neurons. This enhancement in neurogenesis is crucial for cognitive health.
On a mechanistic level, we discovered that THF reduces elevated levels of the protein PTEN, which is known to inhibit cell growth, while simultaneously increasing the levels of phosphorylated AKT and mTOR—proteins essential for cell survival and growth. Additionally, by conditionally removing PTEN from hippocampal neural stem cells, we noticed a reduction in the negative effects ICH typically has on the proliferation of these cells and on neurogenesis.
Overall, our study sheds light on the potential of THF as a therapeutic option for those recovering from hemorrhagic strokes, providing valuable insights into how we might help improve recovery for affected individuals.
Read More
Most Useful Reviews
7.5
Stroke risk explained
1 people found this helpful
A very important vitamin! Vitamin B12 is essential for DNA synthesis, energy production, and maintaining normal nerve function. Along with other B vitamins, it plays a role in the folate cycle. Insufficient B12 can disrupt this process, leading to homocysteine accumulation. This can damage blood vessel walls, increasing the risk of atherosclerosis and blood clots, resulting in heart attacks or strokes. I trust Now Foods; the lozenges' shape is convenient, and the packaging is small. I recommend it!
Read More
7.5
Prevents strokes
As a source of methyl groups, cyanocobalamin (vitamin B12) has significant lipotropic properties, helps prevent fatty liver infiltration, and enhances immunological reactivity by increasing leukocyte phagocytosis. It regulates the function of blood-forming organs and may reduce symptoms of senile dementia. Additionally, it helps to lower homocysteine levels, reducing the risk of strokes. This vitamin is essential for reproductive health and improves sperm content. It’s a brilliant product; use it and stay healthy!
Read More
7.5
Metabolism support
Vitamin B12 helps maintain normal metabolism of amino acids, fats, and carbohydrates, ensures proper nerve function, and protects blood vessel walls, aiding in the prevention of cardiovascular diseases. It prevents anaemia, heart attacks, and strokes. Regular intake strengthens bones and promotes proper metabolism.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 25 Researches
7.3
- All Researches
9
B12 deficiency mimics stroke symptoms
We examined a fascinating case involving a 53-year-old woman who showed atypical signs of vitamin B12 deficiency, resulting in gait instability that mimicked stroke symptoms. Neuroimaging confirmed spinal cord damage typical of subacute combined degeneration, while lab tests showed low B12 levels.
Despite the absence of classic symptoms, the patient responded remarkably well to immediate B12 treatment, restoring her gait stability and neurological functions. This emphasizes the importance of recognizing varied symptoms of B12 deficiency and the need for swift intervention.
Despite the absence of classic symptoms, the patient responded remarkably well to immediate B12 treatment, restoring her gait stability and neurological functions. This emphasizes the importance of recognizing varied symptoms of B12 deficiency and the need for swift intervention.
Read More
9
We explored the cost-effectiveness of different folic acid supplementation strategies aimed at preventing strokes in hypertensive individuals in China. By examining four policy options, we aimed to find the best approach to support stroke prevention while considering potential complications from undetected vitamin B12 deficiencies.
The policies varied from simply not addressing folate levels to providing targeted folate supplements after screening for B12 deficiencies. Our analysis, based on a five-year intervention modeled from the China Stroke Primary Prevention Trial, found that the most effective strategy combined folate supplementation with screening for both folate and B12 deficiencies.
This combination not only helped prevent strokes but also ensured that those with B12 deficiency received appropriate treatment. The implications of this research suggest that adopting integrated screening approaches could greatly enhance public nutrition strategies, ultimately saving costs and improving health outcomes for at-risk populations.
The policies varied from simply not addressing folate levels to providing targeted folate supplements after screening for B12 deficiencies. Our analysis, based on a five-year intervention modeled from the China Stroke Primary Prevention Trial, found that the most effective strategy combined folate supplementation with screening for both folate and B12 deficiencies.
This combination not only helped prevent strokes but also ensured that those with B12 deficiency received appropriate treatment. The implications of this research suggest that adopting integrated screening approaches could greatly enhance public nutrition strategies, ultimately saving costs and improving health outcomes for at-risk populations.
Read More
9
We explored the connection between folate levels, homocysteine, and the outcomes of ischemic stroke. In a study involving 3,530 patients, we measured serum folate and homocysteine levels at the time of hospital admission.
Our findings revealed that higher folate levels were linked to a significantly lower risk of death and major disability three months after a stroke. Specifically, patients in the highest quartile of folate had a 29% reduced risk of experiencing adverse outcomes compared to those with the lowest levels.
On the flip side, elevated homocysteine levels seemed to indicate a higher risk; those in the top quartile had a 52% increased chance of facing the primary outcome. After adjusting for various factors, the results still highlighted that while folate may offer protective benefits, some of these effects might be mediated through homocysteine.
In summary, maintaining high levels of folate could be beneficial for stroke patients, potentially reducing their chances of serious complications.
Our findings revealed that higher folate levels were linked to a significantly lower risk of death and major disability three months after a stroke. Specifically, patients in the highest quartile of folate had a 29% reduced risk of experiencing adverse outcomes compared to those with the lowest levels.
On the flip side, elevated homocysteine levels seemed to indicate a higher risk; those in the top quartile had a 52% increased chance of facing the primary outcome. After adjusting for various factors, the results still highlighted that while folate may offer protective benefits, some of these effects might be mediated through homocysteine.
In summary, maintaining high levels of folate could be beneficial for stroke patients, potentially reducing their chances of serious complications.
Read More
9
We explored the impact of folic acid supplementation on stroke prevention through an extensive look at 21 randomized clinical trials from around the world. This analysis involved over 115,000 participants, providing a comprehensive picture of how folate might influence stroke risk.
The findings revealed a noteworthy 10% reduction in stroke risk for those taking folic acid, suggesting that this vitamin plays a beneficial role in safeguarding against strokes. Interestingly, the effectiveness varied depending on whether the participants lived in areas where grains were fortified with folate. We observed a more significant impact in regions without fortified grains, highlighting that the local dietary context matters.
Furthermore, our analysis indicated that individuals without a prior history of stroke or heart issues experienced the most benefits from folic acid. These results emphasize the importance of individualized approaches to stroke prevention, considering both diet and personal health history. Overall, this substantial collection of trials supports the notion that folic acid could be a valuable component in stroke prevention strategies.
The findings revealed a noteworthy 10% reduction in stroke risk for those taking folic acid, suggesting that this vitamin plays a beneficial role in safeguarding against strokes. Interestingly, the effectiveness varied depending on whether the participants lived in areas where grains were fortified with folate. We observed a more significant impact in regions without fortified grains, highlighting that the local dietary context matters.
Furthermore, our analysis indicated that individuals without a prior history of stroke or heart issues experienced the most benefits from folic acid. These results emphasize the importance of individualized approaches to stroke prevention, considering both diet and personal health history. Overall, this substantial collection of trials supports the notion that folic acid could be a valuable component in stroke prevention strategies.
Read More
9
We explored the impact of tetrahydrofolate (THF) on cognitive impairment resulting from intracerebral hemorrhage (ICH), a common type of hemorrhagic stroke. This research is particularly important because ICH can lead to cognitive challenges and significant psychological burdens for patients.
Our findings revealed that administering THF helps restore cognitive function after ICH. By using specially designed Nestin-GFP mice, we observed that THF not only spurs the growth of neural stem cells in the hippocampus but also promotes the creation of new neurons. This enhancement in neurogenesis is crucial for cognitive health.
On a mechanistic level, we discovered that THF reduces elevated levels of the protein PTEN, which is known to inhibit cell growth, while simultaneously increasing the levels of phosphorylated AKT and mTOR—proteins essential for cell survival and growth. Additionally, by conditionally removing PTEN from hippocampal neural stem cells, we noticed a reduction in the negative effects ICH typically has on the proliferation of these cells and on neurogenesis.
Overall, our study sheds light on the potential of THF as a therapeutic option for those recovering from hemorrhagic strokes, providing valuable insights into how we might help improve recovery for affected individuals.
Our findings revealed that administering THF helps restore cognitive function after ICH. By using specially designed Nestin-GFP mice, we observed that THF not only spurs the growth of neural stem cells in the hippocampus but also promotes the creation of new neurons. This enhancement in neurogenesis is crucial for cognitive health.
On a mechanistic level, we discovered that THF reduces elevated levels of the protein PTEN, which is known to inhibit cell growth, while simultaneously increasing the levels of phosphorylated AKT and mTOR—proteins essential for cell survival and growth. Additionally, by conditionally removing PTEN from hippocampal neural stem cells, we noticed a reduction in the negative effects ICH typically has on the proliferation of these cells and on neurogenesis.
Overall, our study sheds light on the potential of THF as a therapeutic option for those recovering from hemorrhagic strokes, providing valuable insights into how we might help improve recovery for affected individuals.
Read More
User Reviews
USERS' SCORE
Moderately Good
Based on 5 Reviews
7.8
- All Reviews
- Positive Reviews
- Negative Reviews
7.5
Stroke risk explained
1 people found this helpful
A very important vitamin! Vitamin B12 is essential for DNA synthesis, energy production, and maintaining normal nerve function. Along with other B vitamins, it plays a role in the folate cycle. Insufficient B12 can disrupt this process, leading to homocysteine accumulation. This can damage blood vessel walls, increasing the risk of atherosclerosis and blood clots, resulting in heart attacks or strokes. I trust Now Foods; the lozenges' shape is convenient, and the packaging is small. I recommend it!
Read More
7.5
Prevents strokes
As a source of methyl groups, cyanocobalamin (vitamin B12) has significant lipotropic properties, helps prevent fatty liver infiltration, and enhances immunological reactivity by increasing leukocyte phagocytosis. It regulates the function of blood-forming organs and may reduce symptoms of senile dementia. Additionally, it helps to lower homocysteine levels, reducing the risk of strokes. This vitamin is essential for reproductive health and improves sperm content. It’s a brilliant product; use it and stay healthy!
Read More
7.5
Metabolism support
Vitamin B12 helps maintain normal metabolism of amino acids, fats, and carbohydrates, ensures proper nerve function, and protects blood vessel walls, aiding in the prevention of cardiovascular diseases. It prevents anaemia, heart attacks, and strokes. Regular intake strengthens bones and promotes proper metabolism.
Read More
7.5
Stroke protection noted
I take this for a friend with heart issues, as vitamin B12 protects against strokes and heart attacks. It enhances enzyme production. It’s an excellent medication!
Read More
2
Risk factor noted
With caution after 50: The effectiveness of vitamin B12 in older individuals can cause increased blood clotting, leading to coronary heart disease. In severe cases, this escalates the risk of stroke.
Read More
Frequently Asked Questions
7.5
Stroke risk explained
1 people found this helpful
A very important vitamin! Vitamin B12 is essential for DNA synthesis, energy production, and maintaining normal nerve function. Along with other B vitamins, it plays a role in the folate cycle. Insufficient B12 can disrupt this process, leading to homocysteine accumulation. This can damage blood vessel walls, increasing the risk of atherosclerosis and blood clots, resulting in heart attacks or strokes. I trust Now Foods; the lozenges' shape is convenient, and the packaging is small. I recommend it!
7.5
Prevents strokes
As a source of methyl groups, cyanocobalamin (vitamin B12) has significant lipotropic properties, helps prevent fatty liver infiltration, and enhances immunological reactivity by increasing leukocyte phagocytosis. It regulates the function of blood-forming organs and may reduce symptoms of senile dementia. Additionally, it helps to lower homocysteine levels, reducing the risk of strokes. This vitamin is essential for reproductive health and improves sperm content. It’s a brilliant product; use it and stay healthy!
7.5
Stroke protection noted
I take this for a friend with heart issues, as vitamin B12 protects against strokes and heart attacks. It enhances enzyme production. It’s an excellent medication!
2
Risk factor noted
With caution after 50: The effectiveness of vitamin B12 in older individuals can cause increased blood clotting, leading to coronary heart disease. In severe cases, this escalates the risk of stroke.
7
Vitamin B12 deficiency and stroke
We focused on understanding how vitamin B12 levels relate to stroke severity and outcomes. In a study involving 75 patients with ischemic stroke and 75 matched controls, we found stroke patients had notably lower vitamin B12 levels and higher homocysteine levels than the control group.
Specifically, those with the lowest B12 levels faced more severe strokes and worse functional outcomes after discharge. Although this study shows a clear connection, further research is needed to determine if B12 supplementation can genuinely reduce stroke risk or improve recovery.
Specifically, those with the lowest B12 levels faced more severe strokes and worse functional outcomes after discharge. Although this study shows a clear connection, further research is needed to determine if B12 supplementation can genuinely reduce stroke risk or improve recovery.
4
We investigated the link between certain biomarkers and early neurological deterioration (END) in ischemic stroke patients. Our study involved 100 patients from a tertiary care hospital, assessing their neurological health and various biochemical indicators.
While 12% experienced END, we discovered low vitamin B12 levels in those affected compared to those without END. Although we identified some risk factors like substance use, the results indicate that boosting vitamin B12 alone may not significantly alter outcomes. Monitoring these biomarkers can help personalize treatment approaches.
While 12% experienced END, we discovered low vitamin B12 levels in those affected compared to those without END. Although we identified some risk factors like substance use, the results indicate that boosting vitamin B12 alone may not significantly alter outcomes. Monitoring these biomarkers can help personalize treatment approaches.
8
We examined how different dosages of B-vitamins, specifically folic acid, vitamin B12, and vitamin B6, affect stroke prevention. Our review included 14 studies with over 76,000 participants and assessed the risk of stroke after supplementation.
We discovered that in areas lacking sufficient folic acid fortification, this B-vitamin combination significantly lowered stroke risk. Optimal doses were identified at 0.8 mg/d for folic acid and 0.4 mg/d for vitamin B12. However, in regions with adequate fortification, no benefit was observed from supplementation.
We discovered that in areas lacking sufficient folic acid fortification, this B-vitamin combination significantly lowered stroke risk. Optimal doses were identified at 0.8 mg/d for folic acid and 0.4 mg/d for vitamin B12. However, in regions with adequate fortification, no benefit was observed from supplementation.
4
We examined data from over 8,000 adults in the National Health and Examination Survey to understand how vitamin B levels and homocysteine relate to stroke risk.
Our findings revealed complex relationships: higher levels of homocysteine were positively associated with stroke prevalence, while vitamin B6 and folate showed L-shaped trends.
Interestingly, vitamin B12 had a U-shaped relationship with stroke, suggesting both low and high levels might be concerning. These results indicate a need for balanced vitamin levels in stroke prevention.
Our findings revealed complex relationships: higher levels of homocysteine were positively associated with stroke prevalence, while vitamin B6 and folate showed L-shaped trends.
Interestingly, vitamin B12 had a U-shaped relationship with stroke, suggesting both low and high levels might be concerning. These results indicate a need for balanced vitamin levels in stroke prevention.
References
- Saeed Z, Zehra SA, Muhammad A, Ashraf I. Atypical Motor-Predominant Presentation of Subacute Combined Degeneration of Spinal Cord Due to Vitamin B12 Deficiency: A Case Report of Stroke Mimicry in the Absence of Classic Symptoms. Cureus. 2024;16:e74697. doi:10.7759/cureus.74697
- Atam V, Srivastava S, Sharma A, Atam I, Tewari J, et al. Serum Vitamin B12 Levels as a Risk Factor and Prognostic Marker in Patients With Acute Ischemic Stroke at a Tertiary Care Center in Northern India: A Case-Control Study. Cureus. 2024;16:e70473. doi:10.7759/cureus.70473
- Harale M, Oommen A, Faruqi A, Mundada M, Reddy RH, et al. Study of Biochemical Predictors of Early Neurological Deterioration in Ischemic Stroke in a Tertiary Care Hospital. Cureus. 2024;16:e68183. doi:10.7759/cureus.68183
- Jung E, Kook HY, Ryu SJ, Ryu HH, Kim HG. The Association of Vitamin B-12 Plasma Concentration with Stroke Incidence According to Sex. J Nutr. 2024;154:3012. doi:10.1016/j.tjnut.2024.08.002
- Zhou L, Wang J, Wu H, Yu P, He Z, et al. Serum levels of vitamin B12 combined with folate and plasma total homocysteine predict ischemic stroke disease: a retrospective case-control study. Nutr J. 2024;23:76. doi:10.1186/s12937-024-00977-7
- Moti Wala S, AlEdani EM, Samuel EA, Ahmad K, Manongi NJ, et al. Exploring the Nexus: A Systematic Review on the Interplay of the Methylenetetrahydrofolate Reductase (MTHFR) Gene C677T Genotype, Hyperhomocysteinemia, and Spontaneous Cervical/Vertebral Artery Dissection in Young Adults. Cureus. 2024;16:e60878. doi:10.7759/cureus.60878
- Ge Y, Yang C, Zadeh M, Sprague SM, Lin YD, et al. Functional regulation of microglia by vitamin B12 alleviates ischemic stroke-induced neuroinflammation in mice. iScience. 2024;27:109480. doi:10.1016/j.isci.2024.109480
- Zhang N, Wu Z, Bai X, Song Y, Li P, et al. Dosage exploration of combined B-vitamin supplementation in stroke prevention: a meta-analysis and systematic review. Am J Clin Nutr. 2024;119:821. doi:10.1016/j.ajcnut.2023.12.021
- Reis da Silva T. Can supplementing vitamin B12 improve mental health outcomes?: a literature review. Br J Community Nurs. 2024;29:137. doi:10.12968/bjcn.2024.29.3.137
- Rafay A, Abdul Fatir C, Hiba HT, Jamil M, Talha Awan M. Hyperhomocysteinemia Presenting as Stroke in a Young Individual: A Case Report. Cureus. 2024;16:e52381. doi:10.7759/cureus.52381
- Zhou L, Wang J, Li M, Tan Y, Wu Y, et al. Low vitamin B levels may predict the risk of ischemic stroke: A cross-sectional study. J Clin Neurosci. 2023;117:125. doi:10.1016/j.jocn.2023.09.024
- Zhang P, Xie X, Zhang Y. Associations between homocysteine and B vitamins and stroke: a cross-sectional study. Front Neurol. 2023;14:1184141. doi:10.3389/fneur.2023.1184141
- Liang Z, Fan F, Liu B, Li K, Chen H, et al. Association Between Serum Folate Concentrations and 10-Year Stroke Risk in a Prospective Community Cohort: Mediation and Interaction Analyses. Nutrients. 2024;17. doi:10.3390/nu17010159
- Chen X, Bishai D. Revisiting cost-effectiveness of folic acid supplementation in primary stroke prevention in China: considering vitamin B12 deficiency masking issue. BMC Public Health. 2024;24:3540. doi:10.1186/s12889-024-21005-7
- Gonçalves-Pereira J, Mergulhão P, Froes F. Medications to Modify Aspiration Risk: Those That Add to Risk and Those That May Reduce Risk. Semin Respir Crit Care Med. 2024;45:694. doi:10.1055/s-0044-1791827
- Shi M, Zheng J, Liu Y, Mao X, Wu X, et al. Folate, Homocysteine, and Adverse Outcomes After Ischemic Stroke. J Am Heart Assoc. 2024;13:e036527. doi:10.1161/JAHA.124.036527
- Yaldiko A, Coonrod S, Marella P, Hurley L, Jadavji NM. Maternal dietary deficiencies in folic acid or choline reduce primary neuron viability after exposure to hypoxia through increased levels of apoptosis. Nutr Neurosci. 2024. doi:10.1080/1028415X.2024.2398365
- Yang J, Wang J, Li B, Zhang Y. Folic acid for the primary prevention of stroke: a systematic review and meta-analysis. Front Nutr. 2024;11:1288417. doi:10.3389/fnut.2024.1288417
- Zhang N, Zhou Z, Chi X, Fan F, Li S, et al. Folic acid supplementation for stroke prevention: A systematic review and meta-analysis of 21 randomized clinical trials worldwide. Clin Nutr. 2024;43:1706. doi:10.1016/j.clnu.2024.05.034
- Zhang X, Zhang Q, Zhang Q, Wang H, Yin Y, et al. Tetrahydrofolate Attenuates Cognitive Impairment after Hemorrhagic Stroke by Promoting Hippocampal Neurogenesis via PTEN Signaling. eNeuro. 2024;11. doi:10.1523/ENEURO.0021-24.2024
- Shi Y, Zhang Z, Wang B, Wang Y, Kong X, et al. Effect of plateletcrit and methylenetetrahydrofolate reductase (MTHFR) C677T genotypes on folic acid efficacy in stroke prevention. Signal Transduct Target Ther. 2024;9:110. doi:10.1038/s41392-024-01817-0
- Hu X, Jiang Y. The impact of SLCO1B1 polymorphisms on homocysteine concentrations: evidence for a stronger association in men. Front Nephrol. 2024;4:1465380. doi:10.3389/fneph.2024.1465380
- Zhang J, Liao Q, Chen H, Liu F, Sun D, et al. Association of Vitamin B12 and Polymorphism of with Early-Onset Post-Stroke Depression. Neuropsychiatr Dis Treat. 2024;20:2289. doi:10.2147/NDT.S480417
- Park EJ. Association between vitamin B12 status and heart rate variability in patients with ischemic stroke. Medicine (Baltimore). 2023;102:e33428. doi:10.1097/MD.0000000000033428
- Rasyid A, Mesiano T, Kurniawan M, Hidayat R, Eddy Yunus R, et al. Comprehensive Management of Acute Ischemic Stroke in Psoriatic Patient. Case Rep Dermatol Med. 2023;2023:6580971. doi:10.1155/2023/6580971
