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The results were telling. We discovered that nattokinase has protective effects against acute ischemic strokes and plays a significant role in promoting neurogenesis, which is the process of generating new brain cells. Through experiments conducted on rat models, we observed that nattokinase notably increases irisin levels in peripheral blood. Irisin is a protein that has emerged as an interesting player in enhancing cognitive functions.
By linking the increased levels of irisin to improved cognitive abilities, our findings suggest that nattokinase could be a promising therapy for those suffering from PSCI, positioning irisin as a potential target for treatment. Overall, our research highlights the exciting possibilities that nattokinase offers in the realm of stroke recovery and brain health.
Our observations revealed that NK treatment significantly reduced the size of brain injury and enhanced recovery from neurological issues. It also helped lower levels of harmful pro-inflammatory and coagulation substances while reducing oxidative stress markers in the affected brain area. These findings show NK’s potential in protecting the brain from the damaging effects of stroke.
Furthermore, we explored NK's protective properties in laboratory tests simulating neuron injury due to lack of oxygen and glucose. We found that it was effective in countering cell death across these models, working through various biological pathways. However, when we blocked NK's activity with a specific inhibitor, we noticed that its protective effects vanished, demonstrating that NK's enzymatic activity is crucial for its benefits.
Overall, this study highlights the multi-faceted protective role of nattokinase in brain injuries caused by ischemic events, confirming its potential as a therapeutic agent in stroke treatment.
After 60 days, both the Nattospes and control groups showed significant improvements in physical activities, blood pressure, and quality of life. While Nattospes demonstrated beneficial effects on stroke symptoms, it’s important to note that no adverse effects were reported.
The results suggest that Nattospes can safely support stroke recovery. These findings encourage further research into Nattospes as a potential supplement in cardiovascular disease management.
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Our observations revealed that NK treatment significantly reduced the size of brain injury and enhanced recovery from neurological issues. It also helped lower levels of harmful pro-inflammatory and coagulation substances while reducing oxidative stress markers in the affected brain area. These findings show NK’s potential in protecting the brain from the damaging effects of stroke.
Furthermore, we explored NK's protective properties in laboratory tests simulating neuron injury due to lack of oxygen and glucose. We found that it was effective in countering cell death across these models, working through various biological pathways. However, when we blocked NK's activity with a specific inhibitor, we noticed that its protective effects vanished, demonstrating that NK's enzymatic activity is crucial for its benefits.
Overall, this study highlights the multi-faceted protective role of nattokinase in brain injuries caused by ischemic events, confirming its potential as a therapeutic agent in stroke treatment.
While both treatments lowered cholesterol and triglyceride levels, statins achieved greater reductions. Interestingly, nattokinase raised good cholesterol levels, unlike statins. Our study suggests that nattokinase could be a promising alternative in managing atherosclerosis and reducing stroke risk.
The results were telling. We discovered that nattokinase has protective effects against acute ischemic strokes and plays a significant role in promoting neurogenesis, which is the process of generating new brain cells. Through experiments conducted on rat models, we observed that nattokinase notably increases irisin levels in peripheral blood. Irisin is a protein that has emerged as an interesting player in enhancing cognitive functions.
By linking the increased levels of irisin to improved cognitive abilities, our findings suggest that nattokinase could be a promising therapy for those suffering from PSCI, positioning irisin as a potential target for treatment. Overall, our research highlights the exciting possibilities that nattokinase offers in the realm of stroke recovery and brain health.
After 60 days, both the Nattospes and control groups showed significant improvements in physical activities, blood pressure, and quality of life. While Nattospes demonstrated beneficial effects on stroke symptoms, it’s important to note that no adverse effects were reported.
The results suggest that Nattospes can safely support stroke recovery. These findings encourage further research into Nattospes as a potential supplement in cardiovascular disease management.
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Frequently Asked Questions
A stroke occurs when the blood supply to a part of the brain is interrupted or reduced, preventing brain tissue from getting oxygen and nutrients. This can happen in two primary ways: an ischemic stroke, which occurs when a blood vessel supplying blood to the brain is obstructed, often due to a blood clot; and a hemorrhagic stroke, which occurs when a blood vessel in the brain bursts, leading to bleeding in or around the brain. The severity and outcome of a stroke can vary widely depending on the type, location, and amount of brain tissue affected, as well as the speed with which medical treatment is received.
Recognizing the symptoms of a stroke is crucial for prompt treatment and recovery. Common signs include sudden numbness or weakness in the face, arm, or leg, especially on one side of the body, confusion, trouble speaking or understanding speech, vision problems in one or both eyes, and difficulty walking, which may include dizziness or loss of balance coordination. The acronym FAST can help remember the key signs: Face drooping, Arm weakness, Speech difficulty, and Time to call emergency services. If you or someone you know exhibits these symptoms, it's vital to seek immediate medical attention, as timely intervention can significantly improve outcomes.
Nattokinase is an enzyme extracted from a traditional Japanese food called natto, which is made from fermented soybeans. This enzyme is thought to have potential health benefits, primarily for cardiovascular health. Nattokinase is believed to support the breakdown of fibrin in the blood, which can help improve circulation and reduce the risk of blood clot formation. As a dietary supplement, it is often marketed for its possible ability to promote healthy blood flow and cardiovascular function.
While some studies suggest that nattokinase may help reduce blood pressure and enhance overall heart health, research is still ongoing. As with any supplement, it is essential to consult with a healthcare professional before adding nattokinase to your regimen, especially if you are on blood-thinning medications or have underlying health conditions. Overall, while nattokinase might offer some intriguing health benefits, more comprehensive studies are needed to fully understand its efficacy and safety profile.
Based on user reviews, the timeframe for seeing results from this supplement can vary significantly. One user noted that after two months of use, their father's swollen veins improved greatly, and fibrinogen levels dropped noticeably within just 20 days of starting the supplement (Read Review). Another reviewer reported observing improvement in symptoms related to a mini-stroke after only two weeks of use, indicating that earlier benefits might be felt soon after starting the regimen (Read Review).
Overall, users emphasize the importance of consistency and time in achieving the best outcomes, particularly for post-stroke recovery and preventing complications. Following their recommendations, it appears that while some may experience preliminary benefits within a matter of weeks, more substantial results might take a couple of months to fully materialize. Maintaining regular use, as highlighted by several reviewers, appears essential for maximizing the benefits of the supplement for stroke recovery and prevention (Read Review).
Nattokinase, an enzyme derived from the traditional food natto, has gained attention for its potential in stroke treatment and recovery. Recent studies suggest that nattokinase can significantly reduce brain damage associated with ischemic strokes and promote recovery by lowering harmful inflammatory substances and oxidative stress markers [1]. Additionally, research indicates that it may influence neurogenesis and cognitive recovery, enhancing the production of irisin, a protein linked to improved brain functions in those experiencing post-stroke cognitive impairment [2].
Moreover, a randomized controlled trial involving patients recovering from ischemic stroke indicated that a product containing nattokinase, known as Nattospes, resulted in significant improvements in physical activities and overall quality of life, further supporting its role in stroke recovery [3]. The accumulating evidence positions nattokinase as a promising supplement for those affected by stroke, suggesting its multifaceted protective roles and therapeutic potential. However, as with any supplement, individuals should consult healthcare professionals before starting new treatments.
Users have reported a variety of improvements in their symptoms after taking this supplement, particularly in relation to stroke recovery and overall cardiovascular health. One user noted significant improvement in their father's swollen veins and a marked decrease in fibrinogen levels after just 20 days, highlighting the supplement's effectiveness in addressing post-stroke symptoms (Read Review). Another reviewer, who had recently experienced a mini-stroke, observed a noticeable reduction in the thick and slow sensation on one side of their jaw and tongue within two weeks of starting the supplement (Read Review).
Additional reviews support the narrative that this supplement not only thins the blood but may also prevent blood clots, thereby reducing the risk of further strokes. Multiple users emphasized the supplement's function in clearing blood vessels and promoting healthy blood flow as instrumental in their stroke recovery journeys (Read Review). While many have reported favorable outcomes, it is important to note that individual experiences can vary, and consistent use is often cited as crucial for achieving optimal benefits.
Based on user reviews, many individuals have reported positive experiences when combining this supplement with other treatments for stroke management. The supplement appears to effectively promote blood thinning and support blood vessel health, making it a sought-after alternative to traditional options like aspirin (Read Review). Users have noted significant benefits, such as a decrease in swollen veins and improved fibrinogen levels, contributing to better overall cardiovascular health (Read Review). Furthermore, several reviewers emphasized the supplement's effectiveness in clearing blood clots and preventing additional strokes, which many find reassuring during their recovery (Read Review).
Interestingly, users reported that they often use the supplement in conjunction with other forms of treatment, which they believe enhances its efficacy. One reviewer mentioned their positive experience following a mini-stroke, noting improvements in symptoms after starting the supplement alongside their ongoing recovery efforts (Read Review). Overall, these reviews suggest a strong consensus that combining this supplement with other health protocols can be beneficial for those managing stroke recovery and reducing future risks.
Based on user reviews, Nattokinase is often regarded as an effective supplement for those recovering from strokes or trying to prevent them. Users have reported significant improvements in their health after using Nattokinase, with one user saying their father’s fibrinogen levels dropped considerably in just 20 days of use. Another user mentioned taking one capsule daily to maintain normal blood density, implying that they found this dosage effective for their needs (Read Review) (Read Review).
The general consensus among users is that Nattokinase serves as an excellent blood-thinning agent, helping to tackle existing blood clots and reducing the risk of further strokes. Reviews indicate that daily use can enhance blood flow and is considered a safe alternative to traditional medications like aspirin. While specific dosage recommendations are not explicitly mentioned, the recurring theme of daily capsule intake suggests that users find this method beneficial for stroke management and prevention (Read Review) (Read Review).
Our observations revealed that NK treatment significantly reduced the size of brain injury and enhanced recovery from neurological issues. It also helped lower levels of harmful pro-inflammatory and coagulation substances while reducing oxidative stress markers in the affected brain area. These findings show NK’s potential in protecting the brain from the damaging effects of stroke.
Furthermore, we explored NK's protective properties in laboratory tests simulating neuron injury due to lack of oxygen and glucose. We found that it was effective in countering cell death across these models, working through various biological pathways. However, when we blocked NK's activity with a specific inhibitor, we noticed that its protective effects vanished, demonstrating that NK's enzymatic activity is crucial for its benefits.
Overall, this study highlights the multi-faceted protective role of nattokinase in brain injuries caused by ischemic events, confirming its potential as a therapeutic agent in stroke treatment.
The results were telling. We discovered that nattokinase has protective effects against acute ischemic strokes and plays a significant role in promoting neurogenesis, which is the process of generating new brain cells. Through experiments conducted on rat models, we observed that nattokinase notably increases irisin levels in peripheral blood. Irisin is a protein that has emerged as an interesting player in enhancing cognitive functions.
By linking the increased levels of irisin to improved cognitive abilities, our findings suggest that nattokinase could be a promising therapy for those suffering from PSCI, positioning irisin as a potential target for treatment. Overall, our research highlights the exciting possibilities that nattokinase offers in the realm of stroke recovery and brain health.
After 60 days, both the Nattospes and control groups showed significant improvements in physical activities, blood pressure, and quality of life. While Nattospes demonstrated beneficial effects on stroke symptoms, it’s important to note that no adverse effects were reported.
The results suggest that Nattospes can safely support stroke recovery. These findings encourage further research into Nattospes as a potential supplement in cardiovascular disease management.
References
- Yang XY, Wang SL, Xue WC, Zhang YP, Li LL, et al. Nattokinase's Neuroprotective Mechanisms in Ischemic Stroke: Targeting Inflammation, Oxidative Stress, and Coagulation. Antioxid Redox Signal. 2025;42:228. doi:10.1089/ars.2023.0527
- Wu H, Zhang Q, Xu P, Chen J, Duan L, et al. Nattokinase Promotes Post-stroke Neurogenesis and Cognition Recovery via Increasing Circulating Irisin. J Agric Food Chem. 2023;71:11418. doi:10.1021/acs.jafc.2c08718
- Pham PT, Han B, Hoang BX. Nattospes as Effective and Safe Functional Supplements in Management of Stroke. J Med Food. 2020;23:879. doi:10.1089/jmf.2019.0183
- Ren NN, Chen HJ, Li Y, Mcgowan GW, Lin YG. [A clinical study on the effect of nattokinase on carotid artery atherosclerosis and hyperlipidaemia]. Zhonghua Yi Xue Za Zhi. 2017;97:2038. doi:10.3760/cma.j.issn.0376-2491.2017.26.005
