We explored how vitamin A can influence acne treatment, focusing on the effectiveness of its derivatives. According to the findings, oral isotretinoin, a form of vitamin A, showed remarkable efficacy. Patients experienced a significant reduction in lesions—up to 90%—with complete remission in one-quarter of those involved in the study.
Moreover, more than half of the participants reported substantial improvement after treatment. This strong performance suggests that vitamin A plays a key role in managing acne symptoms effectively.
Overall, the evidence we examined indicates that incorporating vitamin A, particularly through isotretinoin, can lead to significant improvements for individuals struggling with acne.
Read More
9
Isotretinoin aids acne treatment
A review of isotretinoin in the treatment of frontal fibrosing alopecia.
We investigated the impact of vitamin A, specifically isotretinoin, on acne through its use in treating frontal fibrosing alopecia (FFA). Our exploration included a comprehensive review of the available research, focusing on its effectiveness in alleviating symptoms related to acne, especially in the context of hair loss and facial papules.
The analysis covered 15 relevant studies involving 232 FFA patients. Remarkably, nearly 90% of these individuals reported a significant reduction in symptoms after daily doses of 10-40 mg of isotretinoin. This indicates that vitamin A, in the form of isotretinoin, effectively addresses not only the physical manifestations of acne but also helps improve overall skin health.
Our findings suggest that isotretinoin holds promise as a treatment option, particularly for those struggling with the dual challenges of FFA and acne. While further research is warranted, the current evidence strongly supports its role in mitigating acne symptoms.
Read More
9
Viaminate significantly improves acne
Viaminate Inhibits Acnes-induced Abnormal Proliferation and Keratinization of HaCat Cells by Regulating the S100A8/S100A9- MAPK Cascade.
We explored how viaminate, a vitamin A acid treatment commonly used in acne therapy, impacts the skin. To investigate this, acne was induced in rat ears using a combination of acne bacteria and sebum. After 30 days of treatment, we saw a remarkable improvement in the thickening and keratin overproduction associated with acne.
Our analysis indicated that viaminate effectively modifies certain pathways related to skin cell behavior. Specifically, we observed a significant reduction in the expression of the S100A8 and S100A9 proteins, which are known to play a role in inflammation and skin proliferation. Furthermore, viaminate suppressed the activity of the MAPK pathway, which is vital for managing skin cell growth and differentiation.
Importantly, when we administered S100A8 and S100A9 proteins alongside viaminate, we found that this reversed its beneficial effects, highlighting the importance of these proteins in viaminate’s mechanism of action. Overall, our findings suggest that viaminate could serve as an effective option for treating acne by regulating cellular processes that contribute to its development.
Read More
Most Useful Reviews
9
Natural and effective
20 people found this helpful
GREAT alternative to synthetic Vitamin A. I’ve dealt with acne for years, and this has helped considerably without the negative side effects associated with synthetic options. It’s pure, natural, and I don’t want to be without it. A great brand too!
Read More
9
Effective acne treatment
2 people found this helpful
This is the best vitamin A! Just one capsule a day supports immunity, skin health, and vision. It has also cleared my facial acne, making it a great value.
Read More
7.5
Reduces acne spots
1 people found this helpful
A week after starting this, my persistent acne spots began to fade and overall breakouts decreased. It also improved my vision when combined with blueberries and lutein, making it easier to see without straining.
Laboratory investigations of liver function and lipid profiles tests before and after oral isotretinoin treatment among Acne valgaris clients at Ibri Polyclinic: A retrospective study.
We conducted a retrospective study to understand how vitamin A, particularly in the form of oral isotretinoin, impacts acne treatment. This powerful medication is often prescribed for severe cases of acne that don’t respond to other treatments.
Our research reviewed medical records of 50 patients aged between 13 and 40 years who received isotretinoin at Ibri Polyclinic from 2012 to 2022. Over the treatment period, we observed notable changes in liver function and lipid profiles among the patients.
Specifically, after treatment, there were increases in liver enzymes indicating changes in liver function, as well as fluctuations in cholesterol and triglyceride levels. These findings suggest potential risks associated with isotretinoin, highlighting the need for careful monitoring.
While isotretinoin does show effectiveness in treating severe acne, there’s an evident impact on liver health and lipid metabolism that we must consider when prescribing this medication. More research is necessary to fully unravel these effects and guide future treatments.
We explored how vitamin A can influence acne treatment, focusing on the effectiveness of its derivatives. According to the findings, oral isotretinoin, a form of vitamin A, showed remarkable efficacy. Patients experienced a significant reduction in lesions—up to 90%—with complete remission in one-quarter of those involved in the study.
Moreover, more than half of the participants reported substantial improvement after treatment. This strong performance suggests that vitamin A plays a key role in managing acne symptoms effectively.
Overall, the evidence we examined indicates that incorporating vitamin A, particularly through isotretinoin, can lead to significant improvements for individuals struggling with acne.
Read More
9
Retinoic acid's enhanced acne treatment
Preparation and evaluation the effects of retinoic acid loaded proliposomal nanofibers on microbial biofilm inhibition.
We explored the effectiveness of retinoic acid, commonly known as vitamin A, for acne treatment using a unique delivery method that combines proliposomes and nanofibers. The goal was to assess how these specially formulated nanofibers, loaded with retinoic acid, could inhibit microbial biofilm formation, a common contributor to acne.
In our study, we created various formulations of blank and retinoic acid-loaded proliposomal nanofibers. By using different ratios of polyvinylpyrrolidone, phosphatidylcholine, and cholesterol, we aimed to optimize the delivery system. Our findings showed that these formulations were able to form liposomes rapidly after hydration and had appropriate characteristics such as vesicle size and stability.
Notably, the ATRA (all-trans retinoic acid) loaded nanofibers demonstrated greater bioadhesion than a commercial cream, suggesting they may adhere better to the skin. The results indicated these nanofibers offered superior antibacterial and anti-biofilm effects compared to retinoic acid alone. This suggests that this innovative delivery method could enhance the effectiveness of vitamin A in acne treatment.
Overall, the study highlights the promising potential of combining nanofibers and liposomes to improve acne treatment outcomes, showing that vitamin A can be more effective when delivered using this advanced method.
Read More
9
Isotretinoin aids acne treatment
A review of isotretinoin in the treatment of frontal fibrosing alopecia.
We investigated the impact of vitamin A, specifically isotretinoin, on acne through its use in treating frontal fibrosing alopecia (FFA). Our exploration included a comprehensive review of the available research, focusing on its effectiveness in alleviating symptoms related to acne, especially in the context of hair loss and facial papules.
The analysis covered 15 relevant studies involving 232 FFA patients. Remarkably, nearly 90% of these individuals reported a significant reduction in symptoms after daily doses of 10-40 mg of isotretinoin. This indicates that vitamin A, in the form of isotretinoin, effectively addresses not only the physical manifestations of acne but also helps improve overall skin health.
Our findings suggest that isotretinoin holds promise as a treatment option, particularly for those struggling with the dual challenges of FFA and acne. While further research is warranted, the current evidence strongly supports its role in mitigating acne symptoms.
Read More
9
Viaminate significantly improves acne
Viaminate Inhibits Acnes-induced Abnormal Proliferation and Keratinization of HaCat Cells by Regulating the S100A8/S100A9- MAPK Cascade.
We explored how viaminate, a vitamin A acid treatment commonly used in acne therapy, impacts the skin. To investigate this, acne was induced in rat ears using a combination of acne bacteria and sebum. After 30 days of treatment, we saw a remarkable improvement in the thickening and keratin overproduction associated with acne.
Our analysis indicated that viaminate effectively modifies certain pathways related to skin cell behavior. Specifically, we observed a significant reduction in the expression of the S100A8 and S100A9 proteins, which are known to play a role in inflammation and skin proliferation. Furthermore, viaminate suppressed the activity of the MAPK pathway, which is vital for managing skin cell growth and differentiation.
Importantly, when we administered S100A8 and S100A9 proteins alongside viaminate, we found that this reversed its beneficial effects, highlighting the importance of these proteins in viaminate’s mechanism of action. Overall, our findings suggest that viaminate could serve as an effective option for treating acne by regulating cellular processes that contribute to its development.
GREAT alternative to synthetic Vitamin A. I’ve dealt with acne for years, and this has helped considerably without the negative side effects associated with synthetic options. It’s pure, natural, and I don’t want to be without it. A great brand too!
Read More
9
Effective acne treatment
2 people found this helpful
This is the best vitamin A! Just one capsule a day supports immunity, skin health, and vision. It has also cleared my facial acne, making it a great value.
Read More
7.5
Reduces acne spots
1 people found this helpful
A week after starting this, my persistent acne spots began to fade and overall breakouts decreased. It also improved my vision when combined with blueberries and lutein, making it easier to see without straining.
Read More
9
Cleared acne effectively
I took this to improve my skin and reduce acne. I'm very pleased with the results! It works wonders!
Read More
9
Acne improvement
This beta carotene product is excellent. It's a clean supplement and superior to vitamin A since it's a natural precursor for the body. After beginning this, my acne cleared up almost immediately. I also took a quality vitamin E and vitamin K2 MK4 supplement. I believe I was deficient in fat-soluble vitamins, which caused my skin issues. I recommend increasing your intake of these vitamins if you're facing skin problems.
Acne is a common skin condition that affects people of all ages, though it's especially prevalent among teenagers and young adults. It occurs when hair follicles become clogged with oil and dead skin cells, leading to the formation of pimples, blackheads, and cysts. The main factors contributing to acne include excess oil production, hormonal changes, and the presence of bacteria on the skin. Acne can manifest in various forms, from mild cases with just a few breakouts to more severe forms that can cause significant inflammation and scarring.
Treatment for acne varies depending on its severity and can range from over-the-counter topical treatments like benzoyl peroxide and salicylic acid to prescription medications including retinoids and antibiotics. Lifestyle adjustments, such as maintaining a balanced diet and proper skin hygiene, may also contribute to managing and reducing breakouts. Despite being a common skin issue, the psychological impact of acne should not be underestimated, as it can affect self-esteem and overall quality of life.
Beta carotene is a natural pigment found in many fruits and vegetables, particularly those that are orange, yellow, and green. It is a type of carotenoid, which is a class of antioxidants that give plants their vibrant colors. The body converts beta carotene into vitamin A (retinol), which is essential for maintaining healthy vision, skin, and immune function. Foods rich in beta carotene include carrots, sweet potatoes, butternut squash, and leafy greens like spinach and kale.
In addition to its role in promoting overall health, beta carotene is attractive to those seeking to enhance their diets with antioxidant-rich foods. While supplementation can be beneficial for those with specific deficiencies, obtaining nutrients through whole foods is generally recommended. Most people can safely consume beta carotene through their diet, but it's worth noting that excessive intake from supplements can lead to skin discoloration and other health issues. Therefore, incorporating a variety of colorful fruits and vegetables into your daily meals is the best way to enjoy the benefits of beta carotene while ensuring a balanced intake of essential nutrients.
Beta carotene, a powerful antioxidant found in many fruits and vegetables, may contribute to skin health, but its direct effectiveness in treating acne is not well established. This carotenoid is known for its role in converting to vitamin A in the body, which is important for skin health and may assist in maintaining a clear complexion. Vitamin A is often touted in acne treatments as it helps regulate skin cell production and reduces inflammation. While a diet rich in beta carotene can support general skin health, it should not be solely relied upon as a remedy for acne.
If you are considering using beta carotene supplements specifically for acne treatment, it's essential to consult with a healthcare provider or dermatologist. They can provide tailored advice based on your specific skin type and needs. In sum, while beta carotene can be a beneficial part of a healthy diet and contribute to overall skin health, more research is needed to conclusively determine its effectiveness in treating acne specifically.
According to user reviews, the timeframe for seeing results from this acne supplement can vary. Many users report noticeable improvements within just a week. For instance, one reviewer mentioned that their persistent acne spots began to fade just a week after starting the product, along with a decrease in overall breakouts Read Review. Others have seen significant improvements in their skin condition after a few months of consistent use, with one user noting major improvements after three months Read Review.
Overall, most users indicate that consistent use of the supplement is key to achieving results, with many reporting a reduction in inflammatory acne and clearer skin within a relatively short period, though some may find it takes a few months for full effects to manifest. In general, patience and adherence to the recommended dosage appear crucial for optimal results, as noted by several reviewers who experienced reduced acne after maintaining a regular intake over time Read Review.
The use of vitamin A, particularly in the form of isotretinoin, is supported by a significant body of scientific research for the treatment of acne. Multiple studies have demonstrated its effectiveness in reducing acne lesions and achieving complete remission in severe cases, with some participants experiencing up to a 90% reduction in acne lesions after treatment with isotretinoin [7]. Additionally, isotretinoin is known to regulate skin cell growth and differentiation, helping to manage the underlying causes of acne [5]. Various alternative forms, like viaminate and topical retinoids, have also shown promise in alleviating acne symptoms by targeting inflammatory pathways and improving skin conditions [10][11].
However, it is essential to note that while vitamin A and its derivatives can be highly effective, they come with potential side effects and risks, necessitating careful monitoring during treatment. Studies indicate various systemic effects from isotretinoin, including impacts on liver function and lipid profiles, raising the need for thorough health assessments [2]. Furthermore, some patients may experience emotional fluctuations and anger levels due to the treatment [9]. Overall, while vitamin A supplementation in various forms is scientifically supported for acne treatment, individuals considering such options should consult healthcare professionals for personalized advice and monitoring.
According to user reviews, many individuals have reported marked improvements in their acne symptoms after taking this supplement. For instance, one user highlighted that their persistent acne spots began to fade within a week of starting the product, and overall breakouts decreased Read Review. Another reviewer noted significant clarity in their skin after just a few months, emphasizing that maintaining a regular intake was key to these results Read Review. Users have expressed satisfaction with the overall effectiveness, reporting experiences of clearer skin, smooth texture, and fewer inflamed spots Read Review.
Several reviewers praised the supplement for its compound nature, with one mentioning that beta-carotene, as a natural precursor to vitamin A, has worked wonders for their skin issues Read Review. Additionally, a user transitioning from isotretinoin to this supplement noted a significant reduction in acne without the drying effects commonly associated with other treatments Read Review. While results can differ from person to person, a large number of users appear to agree on the positive impact of this supplement on skin health, with improvements ranging from reduced breakouts to overall enhanced skin appearance.
Based on user reviews, many individuals have reported positive outcomes when combining this supplement with other nutrients for acne management. One reviewer noted significant improvements in their skin condition after incorporating vitamin B-6 and zinc alongside the beta-carotene, reporting a marked reduction in inflamed spots, which made their acne struggle more manageable Read Review. Another user, who transitioned from isotretinoin, mentioned observing substantial acne reduction while adding vitamin C to their regimen, finding it beneficial without the drying effects often tied to harsher treatments Read Review.
Users have also expressed that a holistic approach, including the intake of various fat-soluble vitamins, has led to clearer skin. For example, one reviewer indicated that taking vitamin E and vitamin K2 MK4 alongside beta-carotene was instrumental in addressing their skin issues, attributing their previous acne to deficiencies in these vitamins Read Review. Overall, the consensus among users appears to highlight that effective acne management might be best achieved through a combination of this supplement with other beneficial vitamins and minerals.
Users report varying dosages of Beta Carotene for treating acne, with many finding success with just one capsule per day. For instance, one user noted that a single daily capsule supports skin health while effectively clearing acne outbreaks Read Review. Some suggest taking one capsule every other day, which also yielded positive results in improving skin clarity Read Review.
Others highlighted the importance of not exceeding safe doses, as excessive vitamin A can produce adverse effects. One review emphasized the difference in how they managed their intake with the recommendation to take it morning and evening, leading to significant improvements over three months Read Review. Generally, users have found that moderate doses of Beta Carotene, either alone or in combination with other vitamins, can effectively enhance skin condition and combat acne without the harsh side effects often experienced with traditional acne treatments.
7.5
Reduces acne spots
1 people found this helpful
A week after starting this, my persistent acne spots began to fade and overall breakouts decreased. It also improved my vision when combined with blueberries and lutein, making it easier to see without straining.
7.5
Reduce acne
18 people found this helpful
Safe doses of vitamin A are crucial since excessive intake can have side effects. I take it morning and evening to combat acne and have noticed significant improvement after three months. My skin has cleared up considerably.
7.5
Decreases inflammation
6 people found this helpful
I bought this beta-carotene alongside vitamin B-6 and zinc for acne treatment. The capsules are easy to swallow, and I've noticed a marked improvement in my overall condition. While acne hasn’t completely cleared, major inflamed spots have reduced significantly, making the struggle more manageable. Most importantly, the results are positive!
9
Acne improvement
This beta carotene product is excellent. It's a clean supplement and superior to vitamin A since it's a natural precursor for the body. After beginning this, my acne cleared up almost immediately. I also took a quality vitamin E and vitamin K2 MK4 supplement. I believe I was deficient in fat-soluble vitamins, which caused my skin issues. I recommend increasing your intake of these vitamins if you're facing skin problems.
7.5
Fewer acne outbreaks
2 people found this helpful
I initially took isotretinoin but switched to this product alongside vitamin C. I've noticed a significant reduction in acne without drying out my skin. While I'm not certain about continuing, the results have been promising.
9
Effective acne treatment
2 people found this helpful
This is the best vitamin A! Just one capsule a day supports immunity, skin health, and vision. It has also cleared my facial acne, making it a great value.
7.5
Skin clarity boost
I started taking one capsule every other day to help with acne and oily skin, and I've seen a marked improvement in my skin clarity. This supplement is excellent.
We explored how vitamin A can influence acne treatment, focusing on the effectiveness of its derivatives. According to the findings, oral isotretinoin, a form of vitamin A, showed remarkable efficacy. Patients experienced a significant reduction in lesions—up to 90%—with complete remission in one-quarter of those involved in the study.
Moreover, more than half of the participants reported substantial improvement after treatment. This strong performance suggests that vitamin A plays a key role in managing acne symptoms effectively.
Overall, the evidence we examined indicates that incorporating vitamin A, particularly through isotretinoin, can lead to significant improvements for individuals struggling with acne.
4
Vitamin A's variable impact on acne
Molecular Interactions of Selective Agonists and Antagonists with the Retinoic Acid Receptor γ.
We explored the role of vitamin A, specifically its active form, all-trans retinoic acid (ATRA), in the treatment of acne. Retinoids like ATRA are known for their ability to influence skin cell growth and differentiation, which is important when it comes to managing acne.
Our findings suggest that ATRA interacts with specific receptors in the body, helping to regulate acne-related processes. By binding to retinoic acid receptors, ATRA may assist in controlling the factors that lead to acne breakouts.
It's worth noting that while retinoids show potential, effective treatments depend on various factors, including individual responses. We observed that newer modifications to retinoid compounds may enhance their efficacy in treating acne.
Overall, while vitamin A does have a role in acne treatment, the effectiveness can vary, and more research is necessary to determine the best approaches for different individuals.
9
Viaminate significantly improves acne
Viaminate Inhibits Acnes-induced Abnormal Proliferation and Keratinization of HaCat Cells by Regulating the S100A8/S100A9- MAPK Cascade.
We explored how viaminate, a vitamin A acid treatment commonly used in acne therapy, impacts the skin. To investigate this, acne was induced in rat ears using a combination of acne bacteria and sebum. After 30 days of treatment, we saw a remarkable improvement in the thickening and keratin overproduction associated with acne.
Our analysis indicated that viaminate effectively modifies certain pathways related to skin cell behavior. Specifically, we observed a significant reduction in the expression of the S100A8 and S100A9 proteins, which are known to play a role in inflammation and skin proliferation. Furthermore, viaminate suppressed the activity of the MAPK pathway, which is vital for managing skin cell growth and differentiation.
Importantly, when we administered S100A8 and S100A9 proteins alongside viaminate, we found that this reversed its beneficial effects, highlighting the importance of these proteins in viaminate’s mechanism of action. Overall, our findings suggest that viaminate could serve as an effective option for treating acne by regulating cellular processes that contribute to its development.
7
Vitamin A enhances acne treatment
Proteinase K/Retinoic Acid-Loaded Cationic Liposomes as Multifunctional Anti-Acne Therapy to Disorganize Biofilm and Regulate Keratinocyte Proliferation.
We investigated how vitamin A, in the form of retinoic acid (RA), impacts acne treatment when combined with other agents. The study utilized innovative liposomes that encapsulate both proteinase K and RA alongside soyaethyl morpholinium ethosulfate (SME), aiming for a dual action against acne by targeting both bacterial infection and inflammation.
Our findings showed that these multifunctional liposomes not only demonstrated significant antimicrobial effects, reducing bacterial colonies by 62%, but also effectively restrained the hyperproliferation of keratinocytes, the skin cells that can contribute to acne development. Unlike free forms of RA, which could enhance skin irritation, the liposomal version proved to have better skin tolerability.
Additionally, we noted that RA-loaded nanovesicles outperformed traditional free RA in improving skin barrier function. Overall, this study provides promising evidence that using RA within these specialized liposomes could potentially revolutionize acne treatments by effectively managing both the causes and symptoms of this condition.
9.5
Impact of Isotretinoin on Liver Function
Laboratory investigations of liver function and lipid profiles tests before and after oral isotretinoin treatment among Acne valgaris clients at Ibri Polyclinic: A retrospective study.
We conducted a retrospective study to understand how vitamin A, particularly in the form of oral isotretinoin, impacts acne treatment. This powerful medication is often prescribed for severe cases of acne that don’t respond to other treatments.
Our research reviewed medical records of 50 patients aged between 13 and 40 years who received isotretinoin at Ibri Polyclinic from 2012 to 2022. Over the treatment period, we observed notable changes in liver function and lipid profiles among the patients.
Specifically, after treatment, there were increases in liver enzymes indicating changes in liver function, as well as fluctuations in cholesterol and triglyceride levels. These findings suggest potential risks associated with isotretinoin, highlighting the need for careful monitoring.
While isotretinoin does show effectiveness in treating severe acne, there’s an evident impact on liver health and lipid metabolism that we must consider when prescribing this medication. More research is necessary to fully unravel these effects and guide future treatments.
7
Isotretinoin increases anger levels
Effects of oral isotretinoin treatment for acne vulgaris patients on anger responses and the relationship with temperament.
In our exploration of the effects of isotretinoin, a high-dose vitamin A treatment for acne vulgaris, we focused on how it might influence anger levels in patients. We analyzed a group of 100 individuals, half receiving isotretinoin for their acne and half acting as a control group without any medication. This structure allowed us to assess the emotional responses more effectively.
Our findings revealed an interesting connection: patients taking isotretinoin showed increased levels of anger compared to those who weren’t. We particularly noted a correlation between certain temperament traits—like being cyclothymic or hyperthymic—and different anger responses. For instance, individuals with a cyclothymic temperament exhibited anxiety-related behaviors, while those with a hyperthymic temperament had a greater tendency towards certain anger-related thoughts.
Although we delved into how acne treatment can be linked with emotional well-being, it’s important to clarify that while isotretinoin addresses acne effectively, it can also create emotional fluctuations for some individuals. Our study adds a unique perspective by highlighting the psychological dimensions associated with acne treatment, which haven’t been deeply explored in previous research.
References
Abuallut II, Dibaji MQ, Assiri A, Mawkili W, Najmi AY, et al. Oral Isotretinoin-Associated Ocular Effects and Risk Factors: A Cross-Sectional Study. Clin Ophthalmol. 2024;18:4041. 10.2147/OPTH.S491757
Yaqoubi WSAA, Touby SSJA, Hossain MA. Laboratory investigations of liver function and lipid profiles tests before and after oral isotretinoin treatment among Acne valgaris clients at Ibri Polyclinic: A retrospective study. Toxicol Rep. 2024;13:101799. 10.1016/j.toxrep.2024.101799
Tort S, Öztürk ZC, Kaynak-Onurdağ F, Mutlu-Ağardan NB. Preparation and evaluation the effects of retinoic acid loaded proliposomal nanofibers on microbial biofilm inhibition. Pharm Dev Technol. 2024;29:955. 10.1080/10837450.2024.2411034
Kulaklı S, Elmas Telli AC, Sarı İF, Oğuz ID, Kulaklı F. Increased femoral cartilage thickness in acne patients using isotretinoin: could it be a sign of early osteoarthritis?. Arch Dermatol Res. 2024;316:512. 10.1007/s00403-024-03264-x
Powała K, Żołek T, Brown G, Kutner A. Molecular Interactions of Selective Agonists and Antagonists with the Retinoic Acid Receptor γ. Int J Mol Sci. 2024;25. 10.3390/ijms25126568
Hussein RS, Dayel SB, Abahussein O. Prospective study of the effects of isotretinoin and vitamin D levels on severe acne vulgaris. Turk J Med Sci. 2023;53:1732. 10.55730/1300-0144.5742
Algarin YA, Pulumati A, Jaalouk D, Tan J, Nouri K. The role of vitamins and nutrients in rosacea. Arch Dermatol Res. 2024;316:142. 10.1007/s00403-024-02895-4
Shahpar A, Nezhad NZ, Sahaf AS, Ahramiyanpour N. A review of isotretinoin in the treatment of frontal fibrosing alopecia. J Cosmet Dermatol. 2024;23:1956. 10.1111/jocd.16245
Demir EY, Köse ÖK. Effects of oral isotretinoin treatment for acne vulgaris patients on anger responses and the relationship with temperament. Rev Assoc Med Bras (1992). 2023;70:e20230592. 10.1590/1806-9282.20230592
Cao J, Xu M, Zhu L, Xiao S. Viaminate Inhibits Acnes-induced Abnormal Proliferation and Keratinization of HaCat Cells by Regulating the S100A8/S100A9- MAPK Cascade. Curr Drug Targets. 2023;24:1055. 10.2174/0113894501243867230928115205
Tsai MJ, Lin CY, Trousil J, Sung CT, Lee MH, et al. Proteinase K/Retinoic Acid-Loaded Cationic Liposomes as Multifunctional Anti-Acne Therapy to Disorganize Biofilm and Regulate Keratinocyte Proliferation. Int J Nanomedicine. 2023;18:3879. 10.2147/IJN.S416966
Gurel A, Gurel G, Fırat F, Ozgul E, Turkoglu IND, et al. Effect of systemic isotretinoin therapy on semen parameters. Ann Med. 2023;55:2207038. 10.1080/07853890.2023.2207038
Cook MK, Perche PO, Feldman SR. The use of oral vitamin A in acne management: a review. Dermatol Online J. 2022;28. 10.5070/D328559239
Cao J, Xu M, Zhu L, Xiao S. Viaminate ameliorates Propionibacterium acnes-induced acne via inhibition of the TLR2/NF-κB and MAPK pathways in rats. Naunyn Schmiedebergs Arch Pharmacol. 2023;396:1487. 10.1007/s00210-022-02379-0
Kontzias C, Zaino M, Feldman SR. Tretinoin 0.1% and Benzoyl Peroxide 3% Cream for the Treatment of Facial Acne Vulgaris. Ann Pharmacother. 2023;57:1088. 10.1177/10600280221147338
Kosmoski G, Miller D, Coret C, Atillasoy E. A Topical Combination Regimen of Benzoyl Peroxide and Retinol Moisturizer for Mild to Moderate Acne. J Drugs Dermatol. 2022;21:1340. 10.36849/JDD.6845