Overview
SCIENTIFIC SCORE
Questionable
Based on 31 Researches
6.9
USERS' SCORE
Good
Based on 9 Reviews
8.2
Supplement Facts
Serving Size: 2 Softgels
Amount Per Serving
%DV
Calories
20
Total Fat
2 g
3%**
Saturated Fat
0.5 g
3%**
Polyunsaturated Fat
1 g
†
Monounsaturated Fat
0.5 g
†
Fish Oil Concentrate
2 g (2,000 mg)
†
Eicosapentaenoic Acid (EPA)
360 mg
†
Docosahexaenoic Acid (DHA)
240 mg
†
Top Medical Research Studies
8
We investigated the link between omega-3 fatty acids and the timing of menopause. Using a Mendelian randomization approach, we analyzed data from thousands of women to assess how different fatty acids influenced reproductive longevity—specifically, the age at menopause.
Our findings revealed that higher plasma levels of DHA, a type of omega-3, were associated with a delayed onset of menopause. This suggests that increasing DHA could be a potential strategy for extending women's reproductive lifespan.
Our findings revealed that higher plasma levels of DHA, a type of omega-3, were associated with a delayed onset of menopause. This suggests that increasing DHA could be a potential strategy for extending women's reproductive lifespan.
Read More
9
We examined how omega-3 polyunsaturated fatty acids (n-3 PUFA) could protect against vascular issues linked to menopause using an ovariectomized rat model.
In our study, we found that n-3 PUFA supplementation helped maintain baroreflex sensitivity, which typically declines after ovariectomy.
Additionally, the central arterial pressure profile remained stable in treated rats, showing a potential protective effect against postmenopausal vascular issues. This suggests that omega-3 fish oil may offer therapeutic benefits during menopause.
In our study, we found that n-3 PUFA supplementation helped maintain baroreflex sensitivity, which typically declines after ovariectomy.
Additionally, the central arterial pressure profile remained stable in treated rats, showing a potential protective effect against postmenopausal vascular issues. This suggests that omega-3 fish oil may offer therapeutic benefits during menopause.
Read More
8
We investigated how DHA-enriched fish oil affects cognitive challenges associated with menopause, particularly in female mice carrying the APOE4 gene, known to increase Alzheimer's risk. Our findings suggest that while this fish oil improved recognition memory, it did not significantly enhance spatial working memory.
Furthermore, the fish oil raised levels of DHA and other beneficial compounds in the brain, hinting at its potential protective effects against menopause-related cognitive decline, especially for those at higher risk. Overall, our study indicates a promising role for DHA-rich fish oil in supporting brain health during menopause.
Furthermore, the fish oil raised levels of DHA and other beneficial compounds in the brain, hinting at its potential protective effects against menopause-related cognitive decline, especially for those at higher risk. Overall, our study indicates a promising role for DHA-rich fish oil in supporting brain health during menopause.
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Most Useful Reviews
9
Enhances health during menopause
These capsules are excellent and have made a noticeable difference in how I feel during menopause. My nails, skin, and hair have improved. I recommend purchasing them!
Read More
9
Necessary nutrition for menopause
DHA and EPA are vital for brain health and the body's function, especially during menopause. I ensure I get enough omega-3 fatty acids daily for my overall well-being, as they help regulate metabolism and improve health conditions associated with menopause.
Read More
7.5
Enhances emotional wellbeing
Omega-3 fatty acids improve brain function and relieve menopause symptoms, helping to stabilise my emotional state and reduce anxiety.
Read More
Medical Researches
SCIENTIFIC SCORE
Questionable
Based on 31 Researches
6.9
- All Researches
9
We examined the impact of omega 3 fish oil, paired with resistance exercise, on health in postmenopausal women. In our trial, 20 healthy older women took part in either a resistance training program with fish oil or a placebo for eight weeks.
Both groups showed improvements in physical function, but those taking fish oil experienced a notable boost in handgrip strength and lower blood pressure and inflammatory markers.
This suggests that fish oil could enhance muscle function and reduce health risks for women navigating menopause.
Both groups showed improvements in physical function, but those taking fish oil experienced a notable boost in handgrip strength and lower blood pressure and inflammatory markers.
This suggests that fish oil could enhance muscle function and reduce health risks for women navigating menopause.
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9
We explored how omega-3 polyunsaturated fatty acids (PUFA) affect mood changes associated with menopause in ovariectomized rats. Our study revealed that menopause led to anxiety and depression-like behaviors, driven by increased neuroinflammation in the brain.
However, we found that omega-3 supplementation helped shift the brain's inflammatory response towards a healthier balance. The omega-3s not only assisted in reducing the negative mood symptoms but also promoted protective effects against neuroinflammation.
Overall, while omega-3 fatty acids show promise, more research is needed to fully understand their benefits for menopause-related issues.
However, we found that omega-3 supplementation helped shift the brain's inflammatory response towards a healthier balance. The omega-3s not only assisted in reducing the negative mood symptoms but also promoted protective effects against neuroinflammation.
Overall, while omega-3 fatty acids show promise, more research is needed to fully understand their benefits for menopause-related issues.
Read More
9
We examined how omega-3 polyunsaturated fatty acids (n-3 PUFA) could protect against vascular issues linked to menopause using an ovariectomized rat model.
In our study, we found that n-3 PUFA supplementation helped maintain baroreflex sensitivity, which typically declines after ovariectomy.
Additionally, the central arterial pressure profile remained stable in treated rats, showing a potential protective effect against postmenopausal vascular issues. This suggests that omega-3 fish oil may offer therapeutic benefits during menopause.
In our study, we found that n-3 PUFA supplementation helped maintain baroreflex sensitivity, which typically declines after ovariectomy.
Additionally, the central arterial pressure profile remained stable in treated rats, showing a potential protective effect against postmenopausal vascular issues. This suggests that omega-3 fish oil may offer therapeutic benefits during menopause.
Read More
9
We explored the relationship between eicosapentaenoic acid (EPA) intake and estradiol levels in women, specifically focusing on its effects during menopause. The study utilized data from the National Health and Nutrition Examination Survey, which included dietary interviews and serum estradiol level measurements.
Our findings highlighted that higher intakes of EPA were associated with increased estradiol levels in both menopausal and non-menopausal women. Importantly, we noted that EPA intake above a certain threshold was linked to these hormonal changes.
This research suggests that incorporating more EPA into the diet could play a role in regulating estradiol levels, which is particularly beneficial for women's reproductive health during and after menopause. Understanding these connections helps emphasize the importance of nutrition in hormone regulation.
Our findings highlighted that higher intakes of EPA were associated with increased estradiol levels in both menopausal and non-menopausal women. Importantly, we noted that EPA intake above a certain threshold was linked to these hormonal changes.
This research suggests that incorporating more EPA into the diet could play a role in regulating estradiol levels, which is particularly beneficial for women's reproductive health during and after menopause. Understanding these connections helps emphasize the importance of nutrition in hormone regulation.
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9
We explored the relationship between docosahexaenoic acid (DHA), a type of omega-3 fatty acid, and breast density among postmenopausal women, particularly focusing on those who are obese. Our study aimed to understand how DHA might differentially affect breast density in obese versus nonobese women, using a method called iTRAQ to analyze plasma samples over two years.
During the study, we identified 173 proteins in the plasma samples. Some of these proteins showed different levels of expression based on whether women were obese or lean. Notably, proteins like the vitamin D binding protein and fibronectin were altered, which suggests a connection between DHA intake and reduced inflammation in obese women.
Our findings indicated that there is an inverse relationship between DHA levels and breast density specifically in postmenopausal obese women. This suggests that greater DHA intake could potentially reduce breast density and may decrease breast cancer risk in this demographic. However, it’s important to note that the effect was not observed in nonobese women.
Overall, this research highlights DHA's role in impacting breast health during menopause, particularly for those with obesity. It opens up further discussions on how dietary changes could play a role in cancer prevention strategies for women going through menopause.
During the study, we identified 173 proteins in the plasma samples. Some of these proteins showed different levels of expression based on whether women were obese or lean. Notably, proteins like the vitamin D binding protein and fibronectin were altered, which suggests a connection between DHA intake and reduced inflammation in obese women.
Our findings indicated that there is an inverse relationship between DHA levels and breast density specifically in postmenopausal obese women. This suggests that greater DHA intake could potentially reduce breast density and may decrease breast cancer risk in this demographic. However, it’s important to note that the effect was not observed in nonobese women.
Overall, this research highlights DHA's role in impacting breast health during menopause, particularly for those with obesity. It opens up further discussions on how dietary changes could play a role in cancer prevention strategies for women going through menopause.
Read More
User Reviews
USERS' SCORE
Good
Based on 9 Reviews
8.2
- All Reviews
- Positive Reviews
- Negative Reviews
9
Enhances health during menopause
These capsules are excellent and have made a noticeable difference in how I feel during menopause. My nails, skin, and hair have improved. I recommend purchasing them!
Read More
9
Necessary nutrition for menopause
DHA and EPA are vital for brain health and the body's function, especially during menopause. I ensure I get enough omega-3 fatty acids daily for my overall well-being, as they help regulate metabolism and improve health conditions associated with menopause.
Read More
7.5
Enhances emotional wellbeing
Omega-3 fatty acids improve brain function and relieve menopause symptoms, helping to stabilise my emotional state and reduce anxiety.
Read More
7.5
Normal cholesterol achieved
7 people found this helpful
My LDL cholesterol levels have decreased. After hearing that my cholesterol was high post-menopause, I shifted to this supplement for a year and now my levels are within the normal range. I prefer not to take hospital medication and wish to continue this.
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7.5
Reduces menopause symptoms
5 people found this helpful
EPA is abundant in fish and helps reduce inflammation, unlike Omega products. It can alleviate depression and menopause symptoms in women.
Read More
Frequently Asked Questions
9
Enhances health during menopause
These capsules are excellent and have made a noticeable difference in how I feel during menopause. My nails, skin, and hair have improved. I recommend purchasing them!
7.5
Normal cholesterol achieved
7 people found this helpful
My LDL cholesterol levels have decreased. After hearing that my cholesterol was high post-menopause, I shifted to this supplement for a year and now my levels are within the normal range. I prefer not to take hospital medication and wish to continue this.
7.5
Improved menopause symptoms
Omega has a stabilising effect on insomnia, depression, and autonomic dysfunction, especially during menopause or old age. The natural quality ingredients help alleviate stress, enhance brain function, and normalise sleep and mood. The capsules are mid-sized, and GABA, a neurotransmitter, enhances sleep quality when growth hormone is released at night. This helps limit stress factors and promotes deeper, more effective sleep. The dosage is optimal.
7.5
Enhances emotional wellbeing
Omega-3 fatty acids improve brain function and relieve menopause symptoms, helping to stabilise my emotional state and reduce anxiety.
9
Necessary nutrition for menopause
DHA and EPA are vital for brain health and the body's function, especially during menopause. I ensure I get enough omega-3 fatty acids daily for my overall well-being, as they help regulate metabolism and improve health conditions associated with menopause.
7.5
Aids adults during menopause
I gave this to adults as it’s beneficial for menopause. The capsules are a decent size and very useful.
7.5
Supports menopause wellbeing
This product effectively supports me during menopause. It is well-made and beneficial.
8
We investigated the link between omega-3 fatty acids and the timing of menopause. Using a Mendelian randomization approach, we analyzed data from thousands of women to assess how different fatty acids influenced reproductive longevity—specifically, the age at menopause.
Our findings revealed that higher plasma levels of DHA, a type of omega-3, were associated with a delayed onset of menopause. This suggests that increasing DHA could be a potential strategy for extending women's reproductive lifespan.
Our findings revealed that higher plasma levels of DHA, a type of omega-3, were associated with a delayed onset of menopause. This suggests that increasing DHA could be a potential strategy for extending women's reproductive lifespan.
8
We examined how DHA, at a dose of 625 mg, influences menopausal symptoms, sexual function, and overall quality of life in perimenopausal women. Involving 42 participants, we measured multiple aspects of their well-being using reputable indices over six months. Results indicated significant improvements in menopause symptoms and psychological quality of life. Particularly, sexual function scores improved, suggesting benefits for arousal and lubrication. However, physical quality of life showed no meaningful change. Thus, DHA appears promising in alleviating specific menopausal challenges and enhancing the sexual experience.
2
We examined the effects of eicosapentaenoic acid, a type of omega-3 fatty acid, on menopausal symptoms, particularly those pesky vasomotor symptoms (VMS) like hot flashes. In our 12-week study, we conducted a well-structured trial with 355 women, randomly assigning them to receive either eicosapentaenoic acid or a placebo.
Each participant in the omega-3 group received 1.8 grams daily, while keeping some additional participants engaged in yoga, aerobic exercise, or their usual activities. Our main goal was to see whether the omega-3 treatment could lessen the frequency and discomfort of VMS, along with looking at sleep quality, depression, and anxiety levels.
After analyzing the results, we found no substantial differences in VMS frequency or bother when comparing the omega-3 group to the placebo group. In fact, the average reduction in the number of hot flashes per day was quite similar for both groups. Additionally, there were no significant changes reported in sleep quality or mood among those taking omega-3s.
In conclusion, while omega-3s like eicosapentaenoic acid are popular for various health benefits, this study revealed that they do not provide relief from menopause symptoms for sedentary women. We hope our findings can guide future discussions about effective treatments for menopausal discomfort.
Each participant in the omega-3 group received 1.8 grams daily, while keeping some additional participants engaged in yoga, aerobic exercise, or their usual activities. Our main goal was to see whether the omega-3 treatment could lessen the frequency and discomfort of VMS, along with looking at sleep quality, depression, and anxiety levels.
After analyzing the results, we found no substantial differences in VMS frequency or bother when comparing the omega-3 group to the placebo group. In fact, the average reduction in the number of hot flashes per day was quite similar for both groups. Additionally, there were no significant changes reported in sleep quality or mood among those taking omega-3s.
In conclusion, while omega-3s like eicosapentaenoic acid are popular for various health benefits, this study revealed that they do not provide relief from menopause symptoms for sedentary women. We hope our findings can guide future discussions about effective treatments for menopausal discomfort.
7
We examined the impact of a specialized low-lactose milk drink enriched with omega-3 fatty acids, oleic acid, and vitamins on postmenopausal women at moderate cardiovascular risk.
Over 12 months, the women consuming the enriched milk experienced significant improvements in their cholesterol levels and inflammation indicators, while those in the control group showed no changes.
However, we found no substantial effects on bone metabolism markers. This suggests that such dietary inclusions could support cardiovascular health in postmenopausal women.
Over 12 months, the women consuming the enriched milk experienced significant improvements in their cholesterol levels and inflammation indicators, while those in the control group showed no changes.
However, we found no substantial effects on bone metabolism markers. This suggests that such dietary inclusions could support cardiovascular health in postmenopausal women.
7
We examined the potential benefits of omega-3 long chain polyunsaturated fatty acids (LCPUFA) on bone health in post-menopausal women, a group at high risk for osteoporosis.
Using advanced imaging and blood tests, we assessed bone density and markers of bone turnover in 300 women.
While we found some positive associations between a healthier omega-6 to omega-3 ratio and higher bone density in the femur, overall, omega-3 LCPUFA did not show significant benefits across all measures.
Using advanced imaging and blood tests, we assessed bone density and markers of bone turnover in 300 women.
While we found some positive associations between a healthier omega-6 to omega-3 ratio and higher bone density in the femur, overall, omega-3 LCPUFA did not show significant benefits across all measures.
References
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- Gao H, Ying Y, Sun J, Huang Y, Li X, et al. Genetically Determined Plasma Docosahexaenoic Acid Showed a Causal Association with Female Reproductive Longevity-Related Phenotype: A Mendelian Randomization Study. Nutrients. 2024;16. doi:10.3390/nu16234103
- Lee SR, Directo D. Fish Oil Supplementation with Resistance Exercise Training Enhances Physical Function and Cardiometabolic Health in Postmenopausal Women. Nutrients. 2023;15. doi:10.3390/nu15214516
- Feehan O, Magee PJ, Pourshahidi LK, Armstrong DJ, Slevin MM, et al. Associations of long chain polyunsaturated fatty acids with bone mineral density and bone turnover in postmenopausal women. Eur J Nutr. 2023;62:95. doi:10.1007/s00394-022-02933-9
- Decandia D, Landolfo E, Sacchetti S, Gelfo F, Petrosini L, et al. n-3 PUFA Improve Emotion and Cognition during Menopause: A Systematic Review. Nutrients. 2022;14. doi:10.3390/nu14091982
- Pontifex MG, Martinsen A, Saleh RNM, Harden G, Fox C, et al. DHA-Enriched Fish Oil Ameliorates Deficits in Cognition Associated with Menopause and the Genotype in Rodents. Nutrients. 2022;14. doi:10.3390/nu14091698
- Félix-Soriano E, Martínez-Gayo A, Cobo MJ, Pérez-Chávez A, Ibáñez-Santos J, et al. Effects of DHA-Rich n-3 Fatty Acid Supplementation and/or Resistance Training on Body Composition and Cardiometabolic Biomarkers in Overweight and Obese Post-Menopausal Women. Nutrients. 2021;13. doi:10.3390/nu13072465
- Purzand B, Rokhgireh S, Shabani Zanjani M, Eshraghi N, Mohamadianamiri M, et al. The comparison of the effect of soybean and fish oil on supplementation on menopausal symptoms in postmenopausal women: A randomized, double-blind, placebo-controlled trial. Complement Ther Clin Pract. 2020;41:101239. doi:10.1016/j.ctcp.2020.101239
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- Cianci A, Maiolino L, Giunta G, Rapisarda AMC, Di Mauro P, et al. Neurovegetative disorders of perimenopausal women treated with docosahexaenoic acid (DHA, 625 mg). Gynecol Endocrinol. 2017;33:980. doi:10.1080/09513590.2017.1334200
- Fonolla-Joya J, Reyes-García R, García-Martín A, López-Huertas E, Muñoz-Torres M. Daily Intake of Milk Enriched with n-3 Fatty Acids, Oleic Acid, and Calcium Improves Metabolic and Bone Biomarkers in Postmenopausal Women. J Am Coll Nutr. 2016;35:529.
- Alves Luzia L, Mendes Aldrighi J, Teixeira Damasceno NR, Rodrigues Sampaio G, Aparecida Manólio Soares R, et al. FISH OIL AND VITAMIN E CHANGE LIPID PROFILES AND ANTI-LDL-ANTIBODIES IN TWO DIFFERENT ETHNIC GROUPS OF WOMEN TRANSITIONING THROUGH MENOPAUSE. Nutr Hosp. 2015;32:165. doi:10.3305/nh.2015.32.1.9079
- Losurdo P, Grillo A, Panizon E, Zanetti M, Bardelli M, et al. Baroreflex sensitivity and central hemodynamics after omega-3 polyunsaturated fatty acids supplementation in an animal model of menopause. Vascul Pharmacol. 2015;71:65. doi:10.1016/j.vph.2014.12.005
- Tardivo AP, Nahas-Neto J, Orsatti CL, Dias FB, Poloni PF, et al. Effects of omega-3 on metabolic markers in postmenopausal women with metabolic syndrome. Climacteric. 2015;18:290. doi:10.3109/13697137.2014.981521
- Reed SD, Guthrie KA, Newton KM, Anderson GL, Booth-LaForce C, et al. Menopausal quality of life: RCT of yoga, exercise, and omega-3 supplements. Am J Obstet Gynecol. 2014;210:244.e1. doi:10.1016/j.ajog.2013.11.016
- Guo L, Nan Y, Liang K, Yao L, Li J. Association between polyunsaturated fatty acid intake and estradiol levels among U.S. women. Front Nutr. 2024;11:1500705. doi:10.3389/fnut.2024.1500705
- So J, Yao JH, Magadmi R, Matthan NR, Lamon-Fava S. Sex differences in lipid mediators derived from omega-3 fatty acids in older individuals with low-grade chronic inflammation. Prostaglandins Leukot Essent Fatty Acids. 2024;203:102655. doi:10.1016/j.plefa.2024.102655
- Putti JS, Engers VK, Heemann FM, Salomon TB, Benfato MS, et al. Effects of lipoic acid and ω-3 long-chain polyunsaturated fatty acids on the kidney in the ovariectomized rat model of menopause. Nutrition. 2019;66:173. doi:10.1016/j.nut.2019.05.003
- Marinho PM, Salomon TB, Andrade AS, Behling CS, Putti JS, et al. The effect of n-3 long-chain polyunsaturated fatty acids and lipoic acid on the heart in the ovariectomized rat model of menopause. Free Radic Res. 2019;53:669. doi:10.1080/10715762.2019.1620938
- Abshirini M, Siassi F, Koohdani F, Qorbani M, Khosravi S, et al. Higher intake of dietary n-3 PUFA and lower MUFA are associated with fewer menopausal symptoms. Climacteric. 2019;22:195. doi:10.1080/13697137.2018.1547700
- Schüller ÁK, Mena Canata DA, Hackenhaar FS, Engers VK, Heemann FM, et al. Effects of lipoic acid and n-3 long-chain polyunsaturated fatty acid on the liver ovariectomized rat model of menopause. Pharmacol Rep. 2018;70:263. doi:10.1016/j.pharep.2017.10.006
- Dong H, Hutchins-Wiese H, Kleppinger A, Annis K, Liva E, et al. Effects of Omega-3 Polyunsaturated Fatty Acid Supplementation on Bone Turnover in Older Women. Int J Vitam Nutr Res. 2014;84:124. doi:10.1024/0300-9831/a000199
- Cohen LS, Joffe H, Guthrie KA, Ensrud KE, Freeman M, et al. Efficacy of omega-3 for vasomotor symptoms treatment: a randomized controlled trial. Menopause. 2014;21:347. doi:10.1097/GME.0b013e31829e40b8
- Hutchins-Wiese HL, Kleppinger A, Annis K, Liva E, Lammi-Keefe CJ, et al. The impact of supplemental n-3 long chain polyunsaturated fatty acids and dietary antioxidants on physical performance in postmenopausal women. J Nutr Health Aging. 2013;17:76. doi:10.1007/s12603-012-0415-3
- Scuderi G, Contestabile MT, Gagliano C, Iacovello D, Scuderi L, et al. Effects of phytoestrogen supplementation in postmenopausal women with dry eye syndrome: a randomized clinical trial. Can J Ophthalmol. 2012;47:489. doi:10.1016/j.jcjo.2012.08.019
- Wattanathorn J, Thukham-Mee W. Omega-3-Rich Tuna Oil Derived from By-Products of the Canned Tuna Industry Enhances Memory in an Ovariectomized Rat Model of Menopause. Antioxidants (Basel). 2024;13. doi:10.3390/antiox13060637
- Konuri A, Bhat KMR, Rai KS, Gourishetti K, Phaneendra M YS. Supplementation of fenugreek with choline-docosahexaenoic acid attenuates menopause induced memory loss, BDNF and dendritic arborization in ovariectomized rats. Anat Sci Int. 2021;96:197. doi:10.1007/s12565-020-00574-8
- Sun YW, Xu H, Benitez G, Chen KM, Stanley A, et al. Omega-3 Fatty Acids Responsive Proteins and Reduction in Breast Density in Obese Postmenopausal Women. J Proteome Res. 2019;18:3461. doi:10.1021/acs.jproteome.9b00356
- Sparkes C, Gibson R, Sinclair A, Else PL, Meyer BJ. Effect of Low Dose Docosahexaenoic Acid-Rich Fish Oil on Plasma Lipids and Lipoproteins in Pre-Menopausal Women: A Dose⁻Response Randomized Placebo-Controlled Trial. Nutrients. 2018;10. doi:10.3390/nu10101460
- Jin Y, Kim TH, Park Y. Association between erythrocyte levels of n-3 polyunsaturated fatty acids and depression in postmenopausal women using or not using hormone therapy. Menopause. 2016;23:1012. doi:10.1097/GME.0000000000000667
