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NOW Supplements P-5-P
SCIENTIFIC SCORE
Moderately Effective
Based on 3 Researches
8
USERS' SCORE
Moderately Good
Based on 4 Reviews
7.7
Supplement Facts
Serving Size: 1 Veg Capsule
Amount Per Serving
%DV
Vitamin B-6 [from 50 mg Coenzyme Pyridoxal-5-Phosphate (P-5-P) Monohydrate]
33 mg
1941%
Magnesium (from Magnesium Bisglycinate) (TRAACS®)
25 mg
6%

Top Medical Research Studies

9
Vitamin B6 could aid insomnia
A combination of melatonin, vitamin B6 and medicinal plants in the treatment of mild-to-moderate insomnia: A prospective pilot study.
Moderate relevance due to combination
We set out to investigate how vitamin B6 contributes to improving sleep quality in individuals experiencing mild to moderate insomnia. Our study involved 40 participants who were given a combination treatment containing melatonin, vitamin B6, and extracts from various medicinal plants.

Over a period of two weeks, participants documented their sleep experiences using a daily electronic diary. We analyzed changes in sleep quality, total sleep duration, and how well our treatment reduced sleep-related daytime impairments. Encouragingly, participants reported a significant improvement in sleep quality, with an average score rise from 5.4 to 7.3 on a 10-point scale.

Although it is difficult to isolate the specific effects of vitamin B6 alone due to its use alongside other ingredients, our findings do suggest that this vitamin, when combined with melatonin and plant extracts, could support better sleep. Importantly, the treatment was well-tolerated, with no serious side effects reported.

Overall, while vitamin B6 on its own wasn’t examined, its inclusion in a combination treatment appears to play a role in enhancing sleep quality for those struggling with insomnia.
Read More
8
Assessing B6's insomnia effects
The Effects of Magnesium - Melatonin - Vit B Complex Supplementation in Treatment of Insomnia.
Combination treatment effectiveness noted
We investigated how a supplement containing magnesium, melatonin, and vitamin B6 impacts insomnia. The study involved 60 patients diagnosed with insomnia, who were split into a study group and a control group.

The study group received a daily dose of this supplement for three months, while both groups reported their insomnia severity using the Athens Insomnia Scale. Initially, the two groups showed similar scores, indicating mild to moderate insomnia.

After the three-month period, the results were telling. The study group reported a significant improvement, lowering their average insomnia score to mild levels, while the control group remained at moderate insomnia levels. However, it’s essential to note that while vitamin B6 was part of the supplement, we cannot conclusively state its isolated effect on insomnia treatment due to the combination with magnesium and melatonin.

Overall, the findings suggest that magnesium, melatonin, and vitamin B6 together can effectively alleviate insomnia symptoms, benefiting those struggling with sleep issues, regardless of the cause.
Read More
7
Vitamin B6's unclear insomnia effect
Kidney damage in acute intermittent porphyria.
Score indicates moderate relevance
We observed that vitamin B6 deficiency might contribute to insomnia in patients suffering from acute intermittent porphyria (AIP). In a study involving several patients, insomnia was one of the notable symptoms experienced during acute attacks. While vitamin B6 was included in the treatment plan, its isolated effectiveness on insomnia couldn't be precisely determined because it was part of a broader therapeutic approach.

Patients received various treatments, including glucose, sodium chloride, and even phenothiazines, making it difficult to pinpoint whether vitamin B6 alone helped alleviate insomnia. Additionally, the overall improvement seen in these patients suggests that their recovery may result from a combination of therapies rather than solely from vitamin B6 itself. It’s essential to recognize that while vitamin B6 was part of the treatment strategy, we cannot conclusively say it specifically addressed insomnia with the information available.
Read More

Most Useful Reviews

5.5
Boosts energy levels
I love this product; it makes me feel incredibly good and energised but it gives me dreadful insomnia. I take it first thing in the morning, which keeps me going throughout the day and night. I still rated it 5 stars since others seem to have no similar issues.
Read More
7.5
Mind stability improvement
This has been beneficial for my insomnia and has helped stabilise my mind. Along with other supplements and dietary care, I can now fall asleep swiftly and maintain an optimistic outlook, positively influencing my interactions during the day.
Read More
6.8
Relaxed tension slightly
This affordable B6 vitamin is of good quality. It helps manage stress and aids in addressing insomnia, especially when taken at night. However, I found it less effective compared to B6 from other brands.
Read More

Medical Researches

SCIENTIFIC SCORE
Moderately Effective
Based on 3 Researches
8
  • All Researches
9
Vitamin B6 could aid insomnia
A combination of melatonin, vitamin B6 and medicinal plants in the treatment of mild-to-moderate insomnia: A prospective pilot study.
Moderate relevance due to combination
We set out to investigate how vitamin B6 contributes to improving sleep quality in individuals experiencing mild to moderate insomnia. Our study involved 40 participants who were given a combination treatment containing melatonin, vitamin B6, and extracts from various medicinal plants.

Over a period of two weeks, participants documented their sleep experiences using a daily electronic diary. We analyzed changes in sleep quality, total sleep duration, and how well our treatment reduced sleep-related daytime impairments. Encouragingly, participants reported a significant improvement in sleep quality, with an average score rise from 5.4 to 7.3 on a 10-point scale.

Although it is difficult to isolate the specific effects of vitamin B6 alone due to its use alongside other ingredients, our findings do suggest that this vitamin, when combined with melatonin and plant extracts, could support better sleep. Importantly, the treatment was well-tolerated, with no serious side effects reported.

Overall, while vitamin B6 on its own wasn’t examined, its inclusion in a combination treatment appears to play a role in enhancing sleep quality for those struggling with insomnia.
Read More
8
Assessing B6's insomnia effects
The Effects of Magnesium - Melatonin - Vit B Complex Supplementation in Treatment of Insomnia.
Combination treatment effectiveness noted
We investigated how a supplement containing magnesium, melatonin, and vitamin B6 impacts insomnia. The study involved 60 patients diagnosed with insomnia, who were split into a study group and a control group.

The study group received a daily dose of this supplement for three months, while both groups reported their insomnia severity using the Athens Insomnia Scale. Initially, the two groups showed similar scores, indicating mild to moderate insomnia.

After the three-month period, the results were telling. The study group reported a significant improvement, lowering their average insomnia score to mild levels, while the control group remained at moderate insomnia levels. However, it’s essential to note that while vitamin B6 was part of the supplement, we cannot conclusively state its isolated effect on insomnia treatment due to the combination with magnesium and melatonin.

Overall, the findings suggest that magnesium, melatonin, and vitamin B6 together can effectively alleviate insomnia symptoms, benefiting those struggling with sleep issues, regardless of the cause.
Read More
7
Vitamin B6's unclear insomnia effect
Kidney damage in acute intermittent porphyria.
Score indicates moderate relevance
We observed that vitamin B6 deficiency might contribute to insomnia in patients suffering from acute intermittent porphyria (AIP). In a study involving several patients, insomnia was one of the notable symptoms experienced during acute attacks. While vitamin B6 was included in the treatment plan, its isolated effectiveness on insomnia couldn't be precisely determined because it was part of a broader therapeutic approach.

Patients received various treatments, including glucose, sodium chloride, and even phenothiazines, making it difficult to pinpoint whether vitamin B6 alone helped alleviate insomnia. Additionally, the overall improvement seen in these patients suggests that their recovery may result from a combination of therapies rather than solely from vitamin B6 itself. It’s essential to recognize that while vitamin B6 was part of the treatment strategy, we cannot conclusively say it specifically addressed insomnia with the information available.
Read More

User Reviews

USERS' SCORE
Moderately Good
Based on 4 Reviews
7.7
  • All Reviews
  • Positive Reviews
  • Negative Reviews
5.5
Boosts energy levels
I love this product; it makes me feel incredibly good and energised but it gives me dreadful insomnia. I take it first thing in the morning, which keeps me going throughout the day and night. I still rated it 5 stars since others seem to have no similar issues.
7.5
Mind stability improvement
This has been beneficial for my insomnia and has helped stabilise my mind. Along with other supplements and dietary care, I can now fall asleep swiftly and maintain an optimistic outlook, positively influencing my interactions during the day.
6.8
Relaxed tension slightly
This affordable B6 vitamin is of good quality. It helps manage stress and aids in addressing insomnia, especially when taken at night. However, I found it less effective compared to B6 from other brands.
2.5
No improvement observed
I have insomnia and had hoped this would help, but I noticed no effect at all. It’s quite disappointing.
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