Overview
SCIENTIFIC SCORE
Moderately Effective
Based on 16 Researches
8.2
USERS' SCORE
Good
Based on 42 Reviews
8.1
Supplement Facts
Serving Size: 1 Tablet
Amount Per Serving
%DV
Iodine (from Potassium Iodide)
225 mcg
150%
Sodium (from Sodium Alginate)
5 mg
<1%
Potassium (from Potassium Chloride and Iodide)
99 mg
2%
Sodium Alginate
100 mg
†
Top Medical Research Studies
9.5
We looked into the growing concern of iodine deficiency hypothyroidism among children in the United States. This condition, which can lead to cognitive and physical impairments, was thought to be largely eliminated thanks to universal salt iodization started in the 1920s. However, recent trends suggest that iodine deficiency could be reappearing due to increased use of noniodized salts, lower iodine levels in dairy, and dietary restrictions like veganism or food allergies.
Over an 18-month period, we documented a series of cases where three children were diagnosed with iodine deficiency hypothyroidism despite having no underlying thyroid dysfunction. Their clinical presentations varied significantly—some had large goiters while others showed mild or no goiter at all. The results of their biochemical tests also highlighted a range of thyroid-stimulating hormone elevations.
Importantly, all patients returned to normal thyroid function following iodine supplementation. We propose that measuring spot urine iodine levels alongside elevated serum thyroglobulin could serve as a simpler and effective diagnostic approach, moving away from the more complex 24-hour urinary iodine tests. Our findings shine a light on the necessity of addressing iodine deficiency in today’s dietary landscape.
Over an 18-month period, we documented a series of cases where three children were diagnosed with iodine deficiency hypothyroidism despite having no underlying thyroid dysfunction. Their clinical presentations varied significantly—some had large goiters while others showed mild or no goiter at all. The results of their biochemical tests also highlighted a range of thyroid-stimulating hormone elevations.
Importantly, all patients returned to normal thyroid function following iodine supplementation. We propose that measuring spot urine iodine levels alongside elevated serum thyroglobulin could serve as a simpler and effective diagnostic approach, moving away from the more complex 24-hour urinary iodine tests. Our findings shine a light on the necessity of addressing iodine deficiency in today’s dietary landscape.
Read More
9.5
We explored the impact of iodine treatment on hypothyroidism, particularly focusing on a unique case involving a patient who had undergone total entero-colectomy. In this situation, standard methods of administering iodine, such as oral supplements, proved ineffective due to absorption challenges. Our approach utilized ethiodized oil, an iodine-rich contrast agent, which we injected intramuscularly.
We observed that this method not only addressed the patient's goiter but also sustained normal thyroid function for more than five years. The long half-life of ethiodized oil made it an ideal option for patients reliant on parenteral nutrition, who often struggle with iodine deficiency.
This study highlights a promising alternative for individuals facing similar nutritional challenges due to severe digestive issues. Overall, our findings suggest that tailored iodine administration could offer a viable solution for hypothyroidism linked to dietary deficiencies.
We observed that this method not only addressed the patient's goiter but also sustained normal thyroid function for more than five years. The long half-life of ethiodized oil made it an ideal option for patients reliant on parenteral nutrition, who often struggle with iodine deficiency.
This study highlights a promising alternative for individuals facing similar nutritional challenges due to severe digestive issues. Overall, our findings suggest that tailored iodine administration could offer a viable solution for hypothyroidism linked to dietary deficiencies.
Read More
8
We explored a fascinating case involving hypokalemic periodic paralysis (hypo KPP), which is a rare condition where low potassium levels can lead to episodes of severe muscle weakness or paralysis. Our focus was on a young female patient who faced this issue as a complication of her hypothyroidism combined with distal renal tubular acidosis (DRTA).
During her hospital visit, the patient experienced weakness in all four limbs, and we noted absent reflexes, which are common signs associated with hypo KPP. Initial lab tests indicated that she was suffering from hypokalemia and metabolic acidosis related to her hypothyroid condition.
Treatment involved administering intravenous potassium chloride and bicarbonate, which led to quick improvements. While this case illustrates how managing potassium levels can alleviate symptoms, it's essential to note that we can't draw broad conclusions about potassium's overall effectiveness for hypothyroidism without further controlled studies.
This case suggests that potassium supplementation can play a vital role in treating specific complications related to hypothyroidism, especially when accompanied by DRTA.
During her hospital visit, the patient experienced weakness in all four limbs, and we noted absent reflexes, which are common signs associated with hypo KPP. Initial lab tests indicated that she was suffering from hypokalemia and metabolic acidosis related to her hypothyroid condition.
Treatment involved administering intravenous potassium chloride and bicarbonate, which led to quick improvements. While this case illustrates how managing potassium levels can alleviate symptoms, it's essential to note that we can't draw broad conclusions about potassium's overall effectiveness for hypothyroidism without further controlled studies.
This case suggests that potassium supplementation can play a vital role in treating specific complications related to hypothyroidism, especially when accompanied by DRTA.
Read More
Most Useful Reviews
9
Reduced thirst feelings
43 people found this helpful
I found this iodine supplement amazing as it contains calcium iodide rather than kelp, which can vary in iodine content. Since I have hypothyroidism, I often experienced dehydration despite drinking enough water, which left me feeling thirsty. This supplement supports my thyroid function and remarkably reduces my thirst. It's a very effective product, providing honest feedback without any embellishments. I appreciate it!
Read More
8
Increased energy levels
42 people found this helpful
I ordered the iodine after reading reviews on a Russian site and wanted to contribute my experience. During my pregnancy, I was diagnosed with hypothyroidism and treated with hormones. After a long period of homeopathy, although my diagnosis was ultimately removed, I felt significant fatigue and apathy during winter. After taking these pills for two weeks, I noticed a substantial burst of energy, which has been cumulative, allowing my efficiency to improve daily.
Read More
9
Combination advice
6 people found this helpful
Iodine is crucial for the body and should be taken with selenium for better absorption. If one has hypothyroidism or hyperthyroidism, taking iodine with selenium is essential, as hormone intake will no longer be feasible (referring to Eutherox). I also recommend combining Vitamin D 10,000 with iodine and omega for excellent results. 👍 I advise everyone to consider this.
Read More
Medical Researches
SCIENTIFIC SCORE
Moderately Effective
Based on 16 Researches
8.2
- All Researches
9.5
We looked into the growing concern of iodine deficiency hypothyroidism among children in the United States. This condition, which can lead to cognitive and physical impairments, was thought to be largely eliminated thanks to universal salt iodization started in the 1920s. However, recent trends suggest that iodine deficiency could be reappearing due to increased use of noniodized salts, lower iodine levels in dairy, and dietary restrictions like veganism or food allergies.
Over an 18-month period, we documented a series of cases where three children were diagnosed with iodine deficiency hypothyroidism despite having no underlying thyroid dysfunction. Their clinical presentations varied significantly—some had large goiters while others showed mild or no goiter at all. The results of their biochemical tests also highlighted a range of thyroid-stimulating hormone elevations.
Importantly, all patients returned to normal thyroid function following iodine supplementation. We propose that measuring spot urine iodine levels alongside elevated serum thyroglobulin could serve as a simpler and effective diagnostic approach, moving away from the more complex 24-hour urinary iodine tests. Our findings shine a light on the necessity of addressing iodine deficiency in today’s dietary landscape.
Over an 18-month period, we documented a series of cases where three children were diagnosed with iodine deficiency hypothyroidism despite having no underlying thyroid dysfunction. Their clinical presentations varied significantly—some had large goiters while others showed mild or no goiter at all. The results of their biochemical tests also highlighted a range of thyroid-stimulating hormone elevations.
Importantly, all patients returned to normal thyroid function following iodine supplementation. We propose that measuring spot urine iodine levels alongside elevated serum thyroglobulin could serve as a simpler and effective diagnostic approach, moving away from the more complex 24-hour urinary iodine tests. Our findings shine a light on the necessity of addressing iodine deficiency in today’s dietary landscape.
Read More
9.5
We explored the impact of iodine treatment on hypothyroidism, particularly focusing on a unique case involving a patient who had undergone total entero-colectomy. In this situation, standard methods of administering iodine, such as oral supplements, proved ineffective due to absorption challenges. Our approach utilized ethiodized oil, an iodine-rich contrast agent, which we injected intramuscularly.
We observed that this method not only addressed the patient's goiter but also sustained normal thyroid function for more than five years. The long half-life of ethiodized oil made it an ideal option for patients reliant on parenteral nutrition, who often struggle with iodine deficiency.
This study highlights a promising alternative for individuals facing similar nutritional challenges due to severe digestive issues. Overall, our findings suggest that tailored iodine administration could offer a viable solution for hypothyroidism linked to dietary deficiencies.
We observed that this method not only addressed the patient's goiter but also sustained normal thyroid function for more than five years. The long half-life of ethiodized oil made it an ideal option for patients reliant on parenteral nutrition, who often struggle with iodine deficiency.
This study highlights a promising alternative for individuals facing similar nutritional challenges due to severe digestive issues. Overall, our findings suggest that tailored iodine administration could offer a viable solution for hypothyroidism linked to dietary deficiencies.
Read More
9
We embarked on a study to understand the effects of potassium bromate on healing gastric ulcers in rats that underwent thyroidectomy, which models a state of hypothyroidism. By treating groups of rats with potassium bromate or thyroxine, we compared the healing process in both typical and thyroid-removed conditions.
The results revealed that potassium bromate appeared to enhance the healing of gastric ulcers in hypothyroid rats. We observed a decrease in gastric inflammation and swelling, suggesting improved recovery. Additionally, markers for organ health and blood conditions remained normal, and there was a notable reduction in harmful substances linked to cellular stress.
Our findings indicate that low doses of potassium bromate might mimic the effects of thyroid hormone treatment in promoting gastric healing. This is a promising insight into how potassium can potentially support recovery in conditions marked by low thyroid hormone levels, offering a unique perspective on treatment alternatives.
The results revealed that potassium bromate appeared to enhance the healing of gastric ulcers in hypothyroid rats. We observed a decrease in gastric inflammation and swelling, suggesting improved recovery. Additionally, markers for organ health and blood conditions remained normal, and there was a notable reduction in harmful substances linked to cellular stress.
Our findings indicate that low doses of potassium bromate might mimic the effects of thyroid hormone treatment in promoting gastric healing. This is a promising insight into how potassium can potentially support recovery in conditions marked by low thyroid hormone levels, offering a unique perspective on treatment alternatives.
Read More
9
Potassium enhances hypothyroidism treatment
We aimed to investigate how potassium iodide influences the treatment of hypothyroidism when combined with a salidroside-rich extract. Hypothyroidism is a prevalent condition that affects the thyroid gland, and finding effective low-toxicity treatments is essential.
In our study, we focused on an extract from particular roots known to contain salidroside, evaluating its effectiveness using a mercazolyl hypothyroidism model. We discovered that when this extract was used, it significantly lowered levels of thyroid-stimulating hormone and helped increase thyroid hormone levels as well.
The interesting part of our findings lies in the combination therapy. By adding potassium iodide to the salidroside extract, we observed that the therapeutic effect was enhanced by 1.3 times. This means that potassium iodide might work well with the extract, though we cannot separate the effects of potassium from salidroside in this context. Overall, this study suggests a promising approach to improve hypothyroidism treatment through this herbal preparation with the assistance of potassium iodide.
In our study, we focused on an extract from particular roots known to contain salidroside, evaluating its effectiveness using a mercazolyl hypothyroidism model. We discovered that when this extract was used, it significantly lowered levels of thyroid-stimulating hormone and helped increase thyroid hormone levels as well.
The interesting part of our findings lies in the combination therapy. By adding potassium iodide to the salidroside extract, we observed that the therapeutic effect was enhanced by 1.3 times. This means that potassium iodide might work well with the extract, though we cannot separate the effects of potassium from salidroside in this context. Overall, this study suggests a promising approach to improve hypothyroidism treatment through this herbal preparation with the assistance of potassium iodide.
Read More
9
We assessed how effective radioactive iodine (RAI) treatment is for inducing hypothyroidism in adolescents with Graves' disease (GD). This treatment is often considered when initial therapies, like antithyroid drugs, do not yield lasting results.
In our examination, we reviewed the medical records of teenagers under 18 years old who received RAI treatment from January 2007 to December 2022. We identified 14 cases and noted their ages ranged from 9.8 to 17.3 years, with I131 doses varying between 5.8 and 15.0 mCi.
Remarkably, almost all patients responded positively within six months after treatment, with a cure rate of 86%. Most experienced hypothyroidism within three months, reinforcing the necessity of monitoring thyroid function early on. We did observe one case of temporary salivary gland inflammation.
Throughout the follow-up period of up to 13 years, there were no relapses, which speaks to the effectiveness and safety of RAI as an option for these young patients with GD.
In our examination, we reviewed the medical records of teenagers under 18 years old who received RAI treatment from January 2007 to December 2022. We identified 14 cases and noted their ages ranged from 9.8 to 17.3 years, with I131 doses varying between 5.8 and 15.0 mCi.
Remarkably, almost all patients responded positively within six months after treatment, with a cure rate of 86%. Most experienced hypothyroidism within three months, reinforcing the necessity of monitoring thyroid function early on. We did observe one case of temporary salivary gland inflammation.
Throughout the follow-up period of up to 13 years, there were no relapses, which speaks to the effectiveness and safety of RAI as an option for these young patients with GD.
Read More
User Reviews
USERS' SCORE
Good
Based on 42 Reviews
8.1
- All Reviews
- Positive Reviews
- Negative Reviews
9
Reduced thirst feelings
43 people found this helpful
I found this iodine supplement amazing as it contains calcium iodide rather than kelp, which can vary in iodine content. Since I have hypothyroidism, I often experienced dehydration despite drinking enough water, which left me feeling thirsty. This supplement supports my thyroid function and remarkably reduces my thirst. It's a very effective product, providing honest feedback without any embellishments. I appreciate it!
Read More
8
Increased energy levels
42 people found this helpful
I ordered the iodine after reading reviews on a Russian site and wanted to contribute my experience. During my pregnancy, I was diagnosed with hypothyroidism and treated with hormones. After a long period of homeopathy, although my diagnosis was ultimately removed, I felt significant fatigue and apathy during winter. After taking these pills for two weeks, I noticed a substantial burst of energy, which has been cumulative, allowing my efficiency to improve daily.
Read More
9
Combination advice
6 people found this helpful
Iodine is crucial for the body and should be taken with selenium for better absorption. If one has hypothyroidism or hyperthyroidism, taking iodine with selenium is essential, as hormone intake will no longer be feasible (referring to Eutherox). I also recommend combining Vitamin D 10,000 with iodine and omega for excellent results. 👍 I advise everyone to consider this.
Read More
7.5
Weight loss observed
2 people found this helpful
With my hypothyroidism requiring iodine, I consistently take this supplement. I've noticed significant changes: weight loss, reduced puffiness, decreased fatigue, and cravings for sweets. I take it every morning after breakfast and highly recommend it!
Read More
10
Hormone levels normalised
1 people found this helpful
Following my doctor's advice for treating my hypothyroidism, I have taken this iodine supplement alongside L-tyrosine and selenium for two months. Remarkably, my hormone levels have returned to normal, and I wholeheartedly recommend it!
Read More
Frequently Asked Questions
8
Increased energy levels
42 people found this helpful
I ordered the iodine after reading reviews on a Russian site and wanted to contribute my experience. During my pregnancy, I was diagnosed with hypothyroidism and treated with hormones. After a long period of homeopathy, although my diagnosis was ultimately removed, I felt significant fatigue and apathy during winter. After taking these pills for two weeks, I noticed a substantial burst of energy, which has been cumulative, allowing my efficiency to improve daily.
7.5
Weight loss observed
2 people found this helpful
With my hypothyroidism requiring iodine, I consistently take this supplement. I've noticed significant changes: weight loss, reduced puffiness, decreased fatigue, and cravings for sweets. I take it every morning after breakfast and highly recommend it!
10
Hormone levels normalised
1 people found this helpful
Following my doctor's advice for treating my hypothyroidism, I have taken this iodine supplement alongside L-tyrosine and selenium for two months. Remarkably, my hormone levels have returned to normal, and I wholeheartedly recommend it!
7.5
Increased energy
1 people found this helpful
I take this drug to support my thyroid gland; my diagnosis is hypothyroidism. Along with selenium and 10,000 units of vitamin D from the same brand, I feel well and energised. I will continue purchasing these supplements.
9
Combination advice
6 people found this helpful
Iodine is crucial for the body and should be taken with selenium for better absorption. If one has hypothyroidism or hyperthyroidism, taking iodine with selenium is essential, as hormone intake will no longer be feasible (referring to Eutherox). I also recommend combining Vitamin D 10,000 with iodine and omega for excellent results. 👍 I advise everyone to consider this.
8.5
Feeling much better
I use it together with selenium on the recommendation of my endocrinologist for hypothyroidism. I feel much better.
8
Long-term use
I have purchased several products from this brand and am pleased that it is beneficial for hypothyroidism. I intend to use it long-term and repurchase. I hope to know the dosage and precautions for this brand; having such instructions would be ideal.
9
Quality ingredients noted
Good day. I bought this supplement for my mother upon my endocrinologist’s advice due to iodine deficiency and thyroid issues. The chosen ingredients effectively aid individuals with hypothyroidism, as iodine needs to be paired with potassium. The packaging is cost-effective, quality is excellent, and the tablet size is average with visible benefits.
9
Potassium enhances hypothyroidism treatment
We aimed to investigate how potassium iodide influences the treatment of hypothyroidism when combined with a salidroside-rich extract. Hypothyroidism is a prevalent condition that affects the thyroid gland, and finding effective low-toxicity treatments is essential.
In our study, we focused on an extract from particular roots known to contain salidroside, evaluating its effectiveness using a mercazolyl hypothyroidism model. We discovered that when this extract was used, it significantly lowered levels of thyroid-stimulating hormone and helped increase thyroid hormone levels as well.
The interesting part of our findings lies in the combination therapy. By adding potassium iodide to the salidroside extract, we observed that the therapeutic effect was enhanced by 1.3 times. This means that potassium iodide might work well with the extract, though we cannot separate the effects of potassium from salidroside in this context. Overall, this study suggests a promising approach to improve hypothyroidism treatment through this herbal preparation with the assistance of potassium iodide.
In our study, we focused on an extract from particular roots known to contain salidroside, evaluating its effectiveness using a mercazolyl hypothyroidism model. We discovered that when this extract was used, it significantly lowered levels of thyroid-stimulating hormone and helped increase thyroid hormone levels as well.
The interesting part of our findings lies in the combination therapy. By adding potassium iodide to the salidroside extract, we observed that the therapeutic effect was enhanced by 1.3 times. This means that potassium iodide might work well with the extract, though we cannot separate the effects of potassium from salidroside in this context. Overall, this study suggests a promising approach to improve hypothyroidism treatment through this herbal preparation with the assistance of potassium iodide.
8
Potassium treatment in hypothyroidism
We explored an unusual link between potassium levels and hypothyroidism through the cases of two middle-aged individuals who experienced recurrent episodes of hypokalemic paralysis. This form of paralysis, typically associated with low potassium, can sometimes signal underlying thyroid issues, such as hypothyroidism, which can be confusing to diagnose.
Both patients showed significant drops in their potassium levels, at 1.4 and 1.9 mEq/L, and their tests confirmed autoimmune hypothyroidism due to elevated thyroid-stimulating hormone and thyroid antibodies. Treating them with both intravenous and oral potassium helped alleviate their paralysis.
Although potassium treatment was effective in addressing their hypokalemia, we must note that follow-up care included thyroxine supplementation for their thyroid condition. For a year after treatment, there were no further reports of weakness. While potassium played a key role in their immediate recovery, thyroid hormone replacement was also critical in managing their condition long-term.
Both patients showed significant drops in their potassium levels, at 1.4 and 1.9 mEq/L, and their tests confirmed autoimmune hypothyroidism due to elevated thyroid-stimulating hormone and thyroid antibodies. Treating them with both intravenous and oral potassium helped alleviate their paralysis.
Although potassium treatment was effective in addressing their hypokalemia, we must note that follow-up care included thyroxine supplementation for their thyroid condition. For a year after treatment, there were no further reports of weakness. While potassium played a key role in their immediate recovery, thyroid hormone replacement was also critical in managing their condition long-term.
References
- Salami AT, Chukwukaeme C, Olagoke O, Olaleye SB. Low-dose Potassium bromate enhances ischemia-reperfusion-induced gastric ulcer healing in Thyroidectomised Rats. Niger J Physiol Sci. 2023;38:171. doi:10.54548/njps.v38i2.6
- Singh J, Dinkar A, Kumar N, Kumar K. Recurrent hypokalemic paralysis in hypothyroidism. Am J Med Sci. 2023;365:462. doi:10.1016/j.amjms.2023.01.009
- Korbozova NK, Kudrina NO, Zhukova NA, Grazhdannikov AE, Blavachinskaya IV, et al. Antihypothyroid Effect of Salidroside. Molecules. 2022;27. doi:10.3390/molecules27217487
- Achakzai H, Khan S, Amin QK, Ahmed N, Anwar S. Hypokalemic Periodic Paralysis: An Atypical Presentation of Non-autoimmune Hypothyroidism With Distal Renal Tubular Acidosis. Cureus. 2022;14:e24046. doi:10.7759/cureus.24046
- Hamada K, Mizokami T, Maruta T, Higashi K, Konishi K, et al. Thyroid Function of Infants Breastfed by Mothers with Graves Disease Treated with Inorganic Iodine: A Study of 100 Cases. J Endocr Soc. 2021;5:bvaa187. doi:10.1210/jendso/bvaa187
- Sharma R, Mahajan VK, Singh Chauhan P, Mehta KS, Sharma A, et al. The clinico-epidemiological characteristics and therapeutic experience of 152 patients with cutaneous sporotrichosis: a 10-year retrospective study from India. Int J Dermatol. 2021;60:99. doi:10.1111/ijd.15299
- Waśniowska J, Piątkowska E, Pawlicki P, Smoleń S, Kopeć A, et al. Comparative Analysis of Iodine Levels, Biochemical Responses, and Thyroid Gene Expression in Rats Fed Diets with Kale Biofortified with 5,7-Diiodo-8-Quinolinol. Int J Mol Sci. 2025;26. doi:10.3390/ijms26020822
- Cox SE, Wakeling J, Hall T, Williams TL. Survival of radioiodine treated hyperthyroid cats that are euthyroid and hypothyroid after treatment, and effect of levothyroxine supplementation on survival time of cats with iatrogenic hypothyroidism. J Vet Intern Med. 2025;39:e17295. doi:10.1111/jvim.17295
- He J, Dong Y, Chen X, Wang S, Shen Z, et al. Hypothyroidism induced by excessive-iodine is associated in humans with altered hsa-miR-199a-5p/HIF-1α axis and thyroglobulin. J Nutr Biochem. 2025;138:109841. doi:10.1016/j.jnutbio.2025.109841
- Seetharaman S, Sasidharan Pillai S, Ganta A, Millington K, Quintos JB, et al. Iodine Deficiency Hypothyroidism Among Children in the United States - 21st Century Resurgence?. AACE Clin Case Rep. 2024;10:236. doi:10.1016/j.aace.2024.08.003
- Chielens L, Nauwynck E, Bourgeois S, Staels W, Vanbesien J, et al. A Belgian single centre outcome study of radioiodine treatment in adolescents with Graves' disease. Sci Rep. 2024;14:31063. doi:10.1038/s41598-024-82052-z
- Belaid S, Raghu V, Alissa F, Rudolph J. Long lasting effect of intramuscular iodine injection in the treatment of goiter in an intestinal failure patient with complete entero-colectomy. JPGN Rep. 2024;5:561. doi:10.1002/jpr3.12117
- Kasuga Y, Murayama N. Scales in a dog after levothyroxine sodium treatment: A case report. Open Vet J. 2024;14:2707. doi:10.5455/OVJ.2024.v14.i10.21
- Zhang Y, Li X, Wang XJ, Yang JP, Li JM, et al. A case report on congenital hypothyroidism and alpha thalassemia in children with anemia and muscle damage as the main manifestation. Medicine (Baltimore). 2024;103:e39446. doi:10.1097/MD.0000000000039446
- Li X, Cao C. Levothyroxine sodium tablets reversed Hashimoto thyroiditis-induced kidney injury, muscle injury, and lipid metabolism disorder: A case report and literature review. Medicine (Baltimore). 2024;103:e39190. doi:10.1097/MD.0000000000039190
- Li X, Liang K, Dong Y, Li S, Gao Z, et al. Effects and Action Mode of Oleic Acid and Azone on Release and Penetration Process of Levothyroxine Sodium Patches. AAPS PharmSciTech. 2024;25:180. doi:10.1208/s12249-024-02875-x
