Overview
SCIENTIFIC SCORE
Likely Very Effective
Based on 1 Research
9
USERS' SCORE
Good
Based on 3 Reviews
8.6
Supplement Facts
Serving Size: 2 Veg Capsules
Amount Per Serving
%DV
Quercetin
800 mg
**
Bromelain (2,400 GDU/g)
165 mg
**
Top Medical Research Studies
9
Isoquercitrin shows anxiety relief potential
We investigated how isoquercitrin, a major compound from the pequi fruit, may help reduce anxiety, especially during alcohol withdrawal. Our findings showed that both ethanolic extracts from the leaves and pulp of Caryocar coriaceum, as well as isoquercitrin itself, did not have a sedative effect on adult zebrafish, suggesting that they are safe options for potential anxiety treatment.
Throughout our experiments, we administered these treatments to the zebrafish and observed their behavior during periods of alcohol withdrawal. The study indicates that these extracts and isoquercitrin may interact with the GABAergic system, which is known for its role in anxiety regulation. The molecular docking studies we conducted confirmed that isoquercitrin could form a stable complex with GABA, offering insights into how it may provide anxiety relief.
In summary, our research suggests that isoquercitrin and pequi extracts have promising anxiolytic properties that could serve as alternative treatments for anxiety linked to alcohol withdrawal.
Throughout our experiments, we administered these treatments to the zebrafish and observed their behavior during periods of alcohol withdrawal. The study indicates that these extracts and isoquercitrin may interact with the GABAergic system, which is known for its role in anxiety regulation. The molecular docking studies we conducted confirmed that isoquercitrin could form a stable complex with GABA, offering insights into how it may provide anxiety relief.
In summary, our research suggests that isoquercitrin and pequi extracts have promising anxiolytic properties that could serve as alternative treatments for anxiety linked to alcohol withdrawal.
Read More
Most Useful Reviews
9
Minimises anxiety
It has been incredibly useful in minimising my anxiety and inflammation. For me, this is essential.
Read More
7.5
Soothing anxiety
This product really helps to calm and soothe my anxiety.
Read More
9
Anxiety improvement
42 people found this helpful
This product is as effective as Benadryl when taken in sufficient doses! I have chronic hives and anxiety/jitters, and while it took a few days to adjust, I noticed marked improvement in my anxiety symptoms. By increasing the dosage, I found it alleviated my physical anxiety significantly without causing drowsiness.
Read More
Medical Researches
SCIENTIFIC SCORE
Likely Very Effective
Based on 1 Research
9
- All Researches
9
Isoquercitrin shows anxiety relief potential
We investigated how isoquercitrin, a major compound from the pequi fruit, may help reduce anxiety, especially during alcohol withdrawal. Our findings showed that both ethanolic extracts from the leaves and pulp of Caryocar coriaceum, as well as isoquercitrin itself, did not have a sedative effect on adult zebrafish, suggesting that they are safe options for potential anxiety treatment.
Throughout our experiments, we administered these treatments to the zebrafish and observed their behavior during periods of alcohol withdrawal. The study indicates that these extracts and isoquercitrin may interact with the GABAergic system, which is known for its role in anxiety regulation. The molecular docking studies we conducted confirmed that isoquercitrin could form a stable complex with GABA, offering insights into how it may provide anxiety relief.
In summary, our research suggests that isoquercitrin and pequi extracts have promising anxiolytic properties that could serve as alternative treatments for anxiety linked to alcohol withdrawal.
Throughout our experiments, we administered these treatments to the zebrafish and observed their behavior during periods of alcohol withdrawal. The study indicates that these extracts and isoquercitrin may interact with the GABAergic system, which is known for its role in anxiety regulation. The molecular docking studies we conducted confirmed that isoquercitrin could form a stable complex with GABA, offering insights into how it may provide anxiety relief.
In summary, our research suggests that isoquercitrin and pequi extracts have promising anxiolytic properties that could serve as alternative treatments for anxiety linked to alcohol withdrawal.
Read More
User Reviews
USERS' SCORE
Good
Based on 3 Reviews
8.6
- All Reviews
- Positive Reviews
- Negative Reviews
9
Minimises anxiety
It has been incredibly useful in minimising my anxiety and inflammation. For me, this is essential.
Read More
7.5
Soothing anxiety
This product really helps to calm and soothe my anxiety.
Read More
9
Anxiety improvement
42 people found this helpful
This product is as effective as Benadryl when taken in sufficient doses! I have chronic hives and anxiety/jitters, and while it took a few days to adjust, I noticed marked improvement in my anxiety symptoms. By increasing the dosage, I found it alleviated my physical anxiety significantly without causing drowsiness.
Read More
Frequently Asked Questions
7.5
Soothing anxiety
This product really helps to calm and soothe my anxiety.
9
Minimises anxiety
It has been incredibly useful in minimising my anxiety and inflammation. For me, this is essential.
9
Isoquercitrin shows anxiety relief potential
We investigated how isoquercitrin, a major compound from the pequi fruit, may help reduce anxiety, especially during alcohol withdrawal. Our findings showed that both ethanolic extracts from the leaves and pulp of Caryocar coriaceum, as well as isoquercitrin itself, did not have a sedative effect on adult zebrafish, suggesting that they are safe options for potential anxiety treatment.
Throughout our experiments, we administered these treatments to the zebrafish and observed their behavior during periods of alcohol withdrawal. The study indicates that these extracts and isoquercitrin may interact with the GABAergic system, which is known for its role in anxiety regulation. The molecular docking studies we conducted confirmed that isoquercitrin could form a stable complex with GABA, offering insights into how it may provide anxiety relief.
In summary, our research suggests that isoquercitrin and pequi extracts have promising anxiolytic properties that could serve as alternative treatments for anxiety linked to alcohol withdrawal.
Throughout our experiments, we administered these treatments to the zebrafish and observed their behavior during periods of alcohol withdrawal. The study indicates that these extracts and isoquercitrin may interact with the GABAergic system, which is known for its role in anxiety regulation. The molecular docking studies we conducted confirmed that isoquercitrin could form a stable complex with GABA, offering insights into how it may provide anxiety relief.
In summary, our research suggests that isoquercitrin and pequi extracts have promising anxiolytic properties that could serve as alternative treatments for anxiety linked to alcohol withdrawal.
References
- da Rocha YM, Marques LDS, do Nascimento GA, de Oliveira MRC, Moura LFWG, et al. Phytoceutical isoquercitrin and ethanolic extracts from pequi (Caryocar coriaceum Wittm) reverse alcohol withdrawal-induced anxiety in adult zebrafish (Danio rerio). Behav Brain Res. 2025;482:115439. doi:10.1016/j.bbr.2025.115439
