Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 15 Researches
7.1
USERS' SCORE
Moderately Good
Based on 66 Reviews
7.9
Supplement Facts
Serving Size: 2 Veg Capsules
Amount Per Serving
%DV
Saccharomyces boulardii (10 Billion CFU)(Saccharomyces cerevisiae var. boulardii I-3799)
1,000 mg
**
Top Medical Research Studies
8
We analyzed data from two clinical trials involving 579 individuals with Irritable Bowel Syndrome (IBS) to determine how CNCM I-3856 affects symptoms like bloating.
Our findings revealed that during the second month of supplementation, participants experienced significant reductions in both abdominal pain and bloating—up to 14.9% compared to those taking a placebo.
While intestinal symptoms improved, there were no significant differences observed between groups at the end of treatment. However, stool consistency was notably better in those taking CNCM I-3856.
Our findings revealed that during the second month of supplementation, participants experienced significant reductions in both abdominal pain and bloating—up to 14.9% compared to those taking a placebo.
While intestinal symptoms improved, there were no significant differences observed between groups at the end of treatment. However, stool consistency was notably better in those taking CNCM I-3856.
9
We looked into how probiotics, like Saccharomyces boulardii, can help prevent antibiotic-associated diarrhea (AAD) in children. Involving 23 studies with nearly 4,000 participants, our findings indicate a significant benefit from probiotics, with AAD occurring in 8% of the probiotic group versus 19% in the control group.
It appears that probiotics, particularly certain strains, can help keep children's gut health intact during antibiotic treatments. While no serious side effects were recorded, some mild issues like bloating were noted. Overall, moderate evidence supports using these probiotics to ward off AAD.
It appears that probiotics, particularly certain strains, can help keep children's gut health intact during antibiotic treatments. While no serious side effects were recorded, some mild issues like bloating were noted. Overall, moderate evidence supports using these probiotics to ward off AAD.
8
Probiotic treatment resolved infection
We examined a case involving a 41-year-old man who suffered from cramps, bloating, and watery diarrhea after drinking non-potable water. While initial tests ruled out gluten intolerance and other infectious agents, a deeper analysis eventually identified the presence of Blastocystis hominis. This protozoan is known to be associated with chronic intestinal issues and can be waterborne. Remarkably, treatment with the probiotic Saccharomyces boulardii seemed to effectively resolve the infection. This suggests that Saccharomyces boulardii might offer a beneficial approach for managing similar cases.
Most Useful Reviews
9
Reduced bloating nicely
30 people found this helpful
I purchased this product to improve my stomach health. I have observed significant improvements, such as reduced sweetness cravings and no bloating or heaviness in my stomach. The effects were immediate, and I wholeheartedly recommend it.
9
Effective solution
11 people found this helpful
If your stomach feels like a hurricane, try sugar bicardi! Avoid Espumisan; it doesn't work.
9
Pain-free digestion
10 people found this helpful
No more stomach ache. Recommended for my bloating, I am Celiac and had damaging digestive issues for years. After taking this for the first time, my midriff pain disappeared. I hope this effect lasts! My bowels were regulated within a week; I can't imagine being without it now.
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 15 Researches
7.1
- All Researches
9
We looked into how probiotics, like Saccharomyces boulardii, can help prevent antibiotic-associated diarrhea (AAD) in children. Involving 23 studies with nearly 4,000 participants, our findings indicate a significant benefit from probiotics, with AAD occurring in 8% of the probiotic group versus 19% in the control group.
It appears that probiotics, particularly certain strains, can help keep children's gut health intact during antibiotic treatments. While no serious side effects were recorded, some mild issues like bloating were noted. Overall, moderate evidence supports using these probiotics to ward off AAD.
It appears that probiotics, particularly certain strains, can help keep children's gut health intact during antibiotic treatments. While no serious side effects were recorded, some mild issues like bloating were noted. Overall, moderate evidence supports using these probiotics to ward off AAD.
8
Probiotics significantly reduce bloating
We explored the effectiveness of the probiotic supplement Saccharomyces boulardii in reducing bloating and gastric pain among airline pilots suffering from chronic non-atrophic gastritis.
Over four weeks, participants were divided into groups receiving different doses of the probiotic or undergoing watchful waiting.
The results showed that both probiotic doses significantly improved symptoms compared to the control group, but only the high-dose led to notable changes in certain serum markers.
Overall, this suggests that Saccharomyces boulardii could help ease bloating and gastric discomfort in situations where these issues are common.
Over four weeks, participants were divided into groups receiving different doses of the probiotic or undergoing watchful waiting.
The results showed that both probiotic doses significantly improved symptoms compared to the control group, but only the high-dose led to notable changes in certain serum markers.
Overall, this suggests that Saccharomyces boulardii could help ease bloating and gastric discomfort in situations where these issues are common.
8
Saccharomyces boulardii aids bloating relief
In this clinical trial, we evaluated the impact of Saccharomyces boulardii on patients with small intestinal bacterial overgrowth (SIBO) related to systemic sclerosis (SSc).
We examined the effects of S. boulardii alone, with metronidazole, or in combination for two months.
Results showed that both S. boulardii and the combination treatment significantly reduced gastrointestinal symptoms, including bloating, while metronidazole alone had limited success.
Overall, S. boulardii proves beneficial, giving hope to those suffering from related discomfort.
We examined the effects of S. boulardii alone, with metronidazole, or in combination for two months.
Results showed that both S. boulardii and the combination treatment significantly reduced gastrointestinal symptoms, including bloating, while metronidazole alone had limited success.
Overall, S. boulardii proves beneficial, giving hope to those suffering from related discomfort.
8
Probiotic treatment resolved infection
We examined a case involving a 41-year-old man who suffered from cramps, bloating, and watery diarrhea after drinking non-potable water. While initial tests ruled out gluten intolerance and other infectious agents, a deeper analysis eventually identified the presence of Blastocystis hominis. This protozoan is known to be associated with chronic intestinal issues and can be waterborne. Remarkably, treatment with the probiotic Saccharomyces boulardii seemed to effectively resolve the infection. This suggests that Saccharomyces boulardii might offer a beneficial approach for managing similar cases.
8
We explored how probiotics might help prevent antibiotic-associated diarrhea (AAD) in children. By analyzing 23 studies involving almost 4,000 young participants, we found that probiotics significantly reduced AAD incidence compared to placebo or no treatment.
Specifically, AAD occurred in 8% of children receiving probiotics versus 19% in the control groups. We noted that Lactobacillus rhamnosus and Saccharomyces boulardii were among the most effective strains.
While adverse events were mild and rare, further research is needed regarding other probiotic strains, especially for at-risk children.
Specifically, AAD occurred in 8% of children receiving probiotics versus 19% in the control groups. We noted that Lactobacillus rhamnosus and Saccharomyces boulardii were among the most effective strains.
While adverse events were mild and rare, further research is needed regarding other probiotic strains, especially for at-risk children.
User Reviews
USERS' SCORE
Moderately Good
Based on 66 Reviews
7.9
- All Reviews
- Positive Reviews
- Negative Reviews
9
Reduced bloating nicely
30 people found this helpful
I purchased this product to improve my stomach health. I have observed significant improvements, such as reduced sweetness cravings and no bloating or heaviness in my stomach. The effects were immediate, and I wholeheartedly recommend it.
9
Effective solution
11 people found this helpful
If your stomach feels like a hurricane, try sugar bicardi! Avoid Espumisan; it doesn't work.
9
Pain-free digestion
10 people found this helpful
No more stomach ache. Recommended for my bloating, I am Celiac and had damaging digestive issues for years. After taking this for the first time, my midriff pain disappeared. I hope this effect lasts! My bowels were regulated within a week; I can't imagine being without it now.
9
Significant improvement
7 people found this helpful
I suffered from dysbiosis with constant bloating, gas, and mood swings. After trying these Saccharomyces while waiting for my gastroenterologist appointment, I experienced an uplifting change in mood within 15 minutes of taking one. Overall, there was a significant improvement in my bloating and related issues after completing the course.
10
Stomach improvement
6 people found this helpful
No more bloating! My stomach and gas issues persisted until I tried this probiotic yeast. Since then, the bloating has disappeared and my stomach has improved. I've continued taking it; the capsules are easy to swallow, and the quality control is impressive.
Frequently Asked Questions
9
Significant improvement
7 people found this helpful
I suffered from dysbiosis with constant bloating, gas, and mood swings. After trying these Saccharomyces while waiting for my gastroenterologist appointment, I experienced an uplifting change in mood within 15 minutes of taking one. Overall, there was a significant improvement in my bloating and related issues after completing the course.
9
Reduced cravings
5 people found this helpful
Digestive tract: This bacteria is excellent for your gut! My doctor advised taking 10 billion of these twice a day, which I did. After two weeks, my cravings ceased, and bloating along with those strange noises from my stomach disappeared! I wholeheartedly recommend this product. The quality is outstanding as I truly felt the difference.
10
Relieves gas symptoms
2 people found this helpful
It worked incredibly well! I suffer from gas-type irritable bowel syndrome, and this is the first supplement that has worked effectively for me. I had tried various probiotics with little success, and at my worst, I experienced bloating, gas, and diarrhoea. After a month on Saccharomyces, I've been free of bloating and gas, allowing me to eat foods like wheat and beans without issue. Taking one pill before bed is perfect; two causes me bloating and diarrhoea. I am keen to keep using it.
9
Digestive solution
5 people found this helpful
It was a game-changer post-antibiotics for my stomach issues. Taking it daily made a significant difference. The mix helped resolve my digestion issues and bloating. I no longer suffer stomach troubles; this probiotic genuinely works!
9
Candida control successful
3 people found this helpful
This product is incredible for managing candida in my intimate area. The burning and itching sensations have disappeared, and I’ve seen over 50% reduction in discharge—no unpleasant smell or bloating either. I’m combining it with digestive enzymes for great results.
10
Enhanced digestion
3 people found this helpful
I ordered this for my husband based on a doctor's recommendation to restore his intestines post-antibiotics. The benefits for his microbiome are apparent; his bloating has disappeared and bowel movements have improved. He took 2 tablets before meals and experienced noticeable advantages without constipation. He is very pleased with the results.
9
Helps with bloating
1 people found this helpful
The capsule size is medium and easy to swallow. It definitely provides benefits, particularly in helping me cope with bloating. Saccharomyces boulardii is a yeast from the genus Saccharomycetes, named after the French scientist Henry Boulardi who bred it from lychee and mangosteen peels. It normalises stool consistency and microbiological balance in the intestines, reducing the duration and frequency of bowel movements while tackling digestive issues and stopping diarrhoea without causing constipation.
8
Probiotics significantly reduce bloating
We explored the effectiveness of the probiotic supplement Saccharomyces boulardii in reducing bloating and gastric pain among airline pilots suffering from chronic non-atrophic gastritis.
Over four weeks, participants were divided into groups receiving different doses of the probiotic or undergoing watchful waiting.
The results showed that both probiotic doses significantly improved symptoms compared to the control group, but only the high-dose led to notable changes in certain serum markers.
Overall, this suggests that Saccharomyces boulardii could help ease bloating and gastric discomfort in situations where these issues are common.
Over four weeks, participants were divided into groups receiving different doses of the probiotic or undergoing watchful waiting.
The results showed that both probiotic doses significantly improved symptoms compared to the control group, but only the high-dose led to notable changes in certain serum markers.
Overall, this suggests that Saccharomyces boulardii could help ease bloating and gastric discomfort in situations where these issues are common.
8
Saccharomyces boulardii aids bloating relief
In this clinical trial, we evaluated the impact of Saccharomyces boulardii on patients with small intestinal bacterial overgrowth (SIBO) related to systemic sclerosis (SSc).
We examined the effects of S. boulardii alone, with metronidazole, or in combination for two months.
Results showed that both S. boulardii and the combination treatment significantly reduced gastrointestinal symptoms, including bloating, while metronidazole alone had limited success.
Overall, S. boulardii proves beneficial, giving hope to those suffering from related discomfort.
We examined the effects of S. boulardii alone, with metronidazole, or in combination for two months.
Results showed that both S. boulardii and the combination treatment significantly reduced gastrointestinal symptoms, including bloating, while metronidazole alone had limited success.
Overall, S. boulardii proves beneficial, giving hope to those suffering from related discomfort.
4
Pediatric probiotics enhance treatment
We examined the effectiveness of various probiotic supplements in traditional triple therapy for children suffering from Helicobacter pylori infections.
Our analysis included 29 trials and over 3000 participants. The results indicated that adding probiotics, like Saccharomyces boulardii, significantly improved H. pylori eradication rates and reduced side effects.
Specifically, Saccharomyces boulardii was found to be beneficial for managing bloating during treatment. Therefore, using targeted probiotics alongside standard therapy could enhance overall treatment outcomes for young patients.
Our analysis included 29 trials and over 3000 participants. The results indicated that adding probiotics, like Saccharomyces boulardii, significantly improved H. pylori eradication rates and reduced side effects.
Specifically, Saccharomyces boulardii was found to be beneficial for managing bloating during treatment. Therefore, using targeted probiotics alongside standard therapy could enhance overall treatment outcomes for young patients.
7
Saccharomyces boulardii reduces bloating effects
We evaluated the effects of the probiotic Saccharomyces boulardii on bloating in patients undergoing treatment for H. pylori infection. In a randomized controlled trial, 160 adults were divided into two groups: one received standard antibiotics along with Saccharomyces boulardii, while the other was treated with antibiotics alone.
Although the addition of the probiotic resulted in significantly fewer side effects, including bloating, it did not lead to a notable improvement in eradicating H. pylori. This suggests that while Saccharomyces boulardii may help with discomfort, it doesn't enhance the overall success of H. pylori treatment.
Although the addition of the probiotic resulted in significantly fewer side effects, including bloating, it did not lead to a notable improvement in eradicating H. pylori. This suggests that while Saccharomyces boulardii may help with discomfort, it doesn't enhance the overall success of H. pylori treatment.
8
We analyzed data from two clinical trials involving 579 individuals with Irritable Bowel Syndrome (IBS) to determine how CNCM I-3856 affects symptoms like bloating.
Our findings revealed that during the second month of supplementation, participants experienced significant reductions in both abdominal pain and bloating—up to 14.9% compared to those taking a placebo.
While intestinal symptoms improved, there were no significant differences observed between groups at the end of treatment. However, stool consistency was notably better in those taking CNCM I-3856.
Our findings revealed that during the second month of supplementation, participants experienced significant reductions in both abdominal pain and bloating—up to 14.9% compared to those taking a placebo.
While intestinal symptoms improved, there were no significant differences observed between groups at the end of treatment. However, stool consistency was notably better in those taking CNCM I-3856.
7
Yeast treatment shows mixed results
We investigated the effects of EpiCor fermentate on gastrointestinal discomfort and constipation, focusing on bloating. In a randomized double-blind trial, eighty participants tracked their symptoms over six weeks, comparing a yeast-based treatment to a placebo. While the results showed that EpiCor could positively influence gut microbiome composition and improve constipation symptoms, there was no significant direct benefit reported for bloating relief. So, while EpiCor can help with certain bowel issues, its effectiveness may not extend to all gastrointestinal discomforts.
References
- Li M, Xie Y. Efficacy and safety of as an adjuvant therapy for the eradication of : a meta-analysis. Front Cell Infect Microbiol. 2025;15:1441185. doi:10.3389/fcimb.2025.1441185
- Minoretti P, Liaño Riera M, Santiago Sáez A, Gómez Serrano M, García Martín Á. Probiotic Supplementation With Saccharomyces boulardii and Enterococcus faecium Improves Gastric Pain and Bloating in Airline Pilots With Chronic Non-atrophic Gastritis: An Open-Label Study. Cureus. 2024;16:e52502. doi:10.7759/cureus.52502
- García-Collinot G, Madrigal-Santillán EO, Martínez-Bencomo MA, Carranza-Muleiro RA, Jara LJ, et al. Effectiveness of Saccharomyces boulardii and Metronidazole for Small Intestinal Bacterial Overgrowth in Systemic Sclerosis. Dig Dis Sci. 2020;65:1134. doi:10.1007/s10620-019-05830-0
- Angelici MC, Nardis C, Scarpelli R, Ade P. Blastocystis hominis transmission by non-potable water: a case report in Italy. New Microbiol. 2018;41:173.
- Feng JR, Wang F, Qiu X, McFarland LV, Chen PF, et al. Efficacy and safety of probiotic-supplemented triple therapy for eradication of Helicobacter pylori in children: a systematic review and network meta-analysis. Eur J Clin Pharmacol. 2017;73:1199. doi:10.1007/s00228-017-2291-6
- Hayes SR, Vargas AJ. Probiotics for the Prevention of Pediatric Antibiotic-Associated Diarrhea. Explore (NY). 2016;12:463. doi:10.1016/j.explore.2016.08.015
- Goldenberg JZ, Lytvyn L, Steurich J, Parkin P, Mahant S, et al. Probiotics for the prevention of pediatric antibiotic-associated diarrhea. Cochrane Database Syst Rev. 2015. doi:10.1002/14651858.CD004827.pub4
- Zojaji H, Ghobakhlou M, Rajabalinia H, Ataei E, Jahani Sherafat S, et al. The efficacy and safety of adding the probiotic Saccharomyces boulardiito standard triple therapy for eradication of H.pylori: a randomized controlled trial. Gastroenterol Hepatol Bed Bench. 2013;6:S99.
- Polese B, Nicolai E, Genovese D, Verlezza V, La Sala CN, et al. Postprandial Gastrointestinal Function Differs after Acute Administration of Sourdough Compared with Brewer's Yeast Bakery Products in Healthy Adults. J Nutr. 2018;148:202. doi:10.1093/jn/nxx049
- Pinheiro I, Robinson L, Verhelst A, Marzorati M, Winkens B, et al. A yeast fermentate improves gastrointestinal discomfort and constipation by modulation of the gut microbiome: results from a randomized double-blind placebo-controlled pilot trial. BMC Complement Altern Med. 2017;17:441. doi:10.1186/s12906-017-1948-0
- Cayzeele-Decherf A, Pélerin F, Leuillet S, Douillard B, Housez B, et al. CNCM I-3856 in irritable bowel syndrome: An individual subject meta-analysis. World J Gastroenterol. 2017;23:336. doi:10.3748/wjg.v23.i2.336
- Spiller R, Pélerin F, Cayzeele Decherf A, Maudet C, Housez B, et al. Randomized double blind placebo-controlled trial of Saccharomyces cerevisiae CNCM I-3856 in irritable bowel syndrome: improvement in abdominal pain and bloating in those with predominant constipation. United European Gastroenterol J. 2016;4:353. doi:10.1177/2050640615602571
- Pineton de Chambrun G, Neut C, Chau A, Cazaubiel M, Pelerin F, et al. A randomized clinical trial of Saccharomyces cerevisiae versus placebo in the irritable bowel syndrome. Dig Liver Dis. 2015;47:119. doi:10.1016/j.dld.2014.11.007
- Moya D, Calsamiglia S, Ferret A, Blanch M, Fandiño JI, et al. Effects of dietary changes and yeast culture (Saccharomyces cerevisiae) on rumen microbial fermentation of Holstein heifers. J Anim Sci. 2009;87:2874. doi:10.2527/jas.2008-1446
- Treem WR, McAdams L, Stanford L, Kastoff G, Justinich C, et al. Sacrosidase therapy for congenital sucrase-isomaltase deficiency. J Pediatr Gastroenterol Nutr. 1999;28:137.
