We explored the effects of the CNCM I-745 probiotic on cholesterol levels and gut bacteria in hamsters with high cholesterol. This controlled study revealed that daily doses significantly lowered total plasma cholesterol and altered gut microbiota. Specifically, we noted that the abundance of certain gut microbes was linked to changes in cholesterol levels and liver gene expression. These findings suggest that this probiotic not only benefits cholesterol levels but also supports gut health, offering potential for safe treatments in managing hypercholesterolemia.
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S. boulardii reduces lung injuryProbiotic Saccharomyces boulardii Alleviates Lung Injury by Reduction of Oxidative Stress and Cytokine Response Induced by Supraceliac Aortic Ischemia-Reperfusion Injury in Rats.
High relevance to heart surgery
We explored the effects of the probiotic Saccharomyces boulardii on lung injury caused by aortic ischemia-reperfusion in rats. Twenty-one rats were divided into three groups, one receiving the probiotic and others receiving saline.
After the aorta was clamped, we noticed that those treated with S. boulardii experienced significantly less lung damage and reduced oxidative stress. This suggests the probiotic helps lower inflammation and oxidative stress markers, potentially leading to better outcomes in cardiovascular procedures.
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We explored the role of selenium and zinc enriched postbiotic yeast in addressing gut dysbiosis linked to cardiovascular disease. This study involved analyzing the effects of these postbiotics on microbial populations in the digestive system using various scientific methods.
We found that treatment with the enriched postbiotics led to a notable increase in beneficial bacteria and acetic acid levels. These results suggest that selenium and zinc postbiotics may hold therapeutic potential as adjuncts in treating cardiovascular diseases by improving gut health.
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Probiotic yeast improves heart-healthy fatsFatty acids profile, atherogenic and thrombogenic health lipid indices of lyophilized buckwheat sprouts modified with the addition of Saccharomyces cerevisiae var. boulardii.
Moderate relevance for cardiovascular research
This innovative study evaluated how adding the probiotic yeast Saccharomyces boulardii to buckwheat sprouts affects their fatty acid composition. Through careful analysis, we found that this modification leads to noteworthy changes in fatty acids, including palmitic and oleic acids.
These changes may enhance the nutritional value of buckwheat sprouts, potentially contributing to a reduced risk of cardiovascular disease. Overall, our findings suggest that probiotic-rich buckwheat sprouts could serve as a functional dietary option for heart health.
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Reduced remnant lipoprotein observedEffect of the Probiotic Saccharomyces boulardii on Cholesterol and Lipoprotein Particles in Hypercholesterolemic Adults: A Single-Arm, Open-Label Pilot Study.
Moderate relevance to cardiovascular health
We investigated how the probiotic yeast Saccharomyces boulardii affects blood cholesterol levels in adults with high cholesterol. In this single-arm, open-label pilot study, twelve participants took a specified dose of S. boulardii for eight weeks. While we monitored various cholesterol levels and cardiovascular health markers, results showed a noteworthy reduction in remnant lipoprotein, which could play a role in preventing coronary artery disease. However, overall cholesterol levels did not significantly change during the study.
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