Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 8 Researches
7.9
USERS' SCORE
Good
Based on 2 Reviews
8.5
Supplement Facts
Serving Size: 2 Veg Capsules
Amount Per Serving
%DV
Calories
5
Total Carbohydrate
1 g
<1%**
Milk Thistle Extract (Silybum marianum)(Fruit/Seeds) (Standardized to 240 mg Silymarin Flavonoids - equivalent 80%)
300 mg
†
Turmeric (Curcuma longa) (Root)
700 mg
†
Top Medical Research Studies
8
We explored how silymarin helps with obesity and muscle atrophy in mice. In our study, we divided the mice into three groups: a control group on a normal diet, another group on a high-fat diet, and a third group receiving silymarin alongside the high-fat diet.
The results showed that the silymarin group had less weight gain and maintained better muscle mass compared to the high-fat diet group. Moreover, the grip strength of the mice on silymarin improved. Overall, silymarin seems beneficial for not only tackling obesity but also preserving muscle health.
The results showed that the silymarin group had less weight gain and maintained better muscle mass compared to the high-fat diet group. Moreover, the grip strength of the mice on silymarin improved. Overall, silymarin seems beneficial for not only tackling obesity but also preserving muscle health.
Read More
8
Our investigation focused on how dietary milk thistle seeds and seed oil impact obesity-related intestinal, liver, and lipid issues, specifically in genetically obese rats. After five weeks, we found that rats supplemented with milk thistle seeds showed more significant improvements in liver fat and cholesterol levels compared to those receiving seed oil.
Notably, the seed group experienced better outcomes in their cecal short-chain fatty acid (SCFA) levels, indicating enhanced gut fermentation. Overall, milk thistle seeds appear to be more effective than oil in tackling obesity-related health challenges in these rats.
Notably, the seed group experienced better outcomes in their cecal short-chain fatty acid (SCFA) levels, indicating enhanced gut fermentation. Overall, milk thistle seeds appear to be more effective than oil in tackling obesity-related health challenges in these rats.
Read More
8
Milk thistle extract may aid obesity
We explored the potential of a silymarin-enriched extract from milk thistle to aid in managing obesity and related inflammation. This study tested the extract's effect on activating thermogenesis in a model of obesity induced by a high-fat diet.
Our findings suggest that the extract helps enhance the body's ability to burn fat, which may be beneficial in preventing metabolic diseases and promoting healthy aging. However, the effectiveness of this treatment as a solution for obesity warrants further investigation.
Our findings suggest that the extract helps enhance the body's ability to burn fat, which may be beneficial in preventing metabolic diseases and promoting healthy aging. However, the effectiveness of this treatment as a solution for obesity warrants further investigation.
Read More
Most Useful Reviews
8
Positive liver results
I found this product very helpful for my family, as it has numerous benefits: it aids in the regeneration of liver cells and protects the liver from harmful substances like alcohol and cigarette smoke. It regulates bilirubin, enhances bile secretion, and improves skin conditions related to the liver. Unfortunately, I experienced an allergic reaction to turmeric in the formulation and opted for a different milk thistle product. However, my husband has had excellent results. He was diagnosed with liver obesity years ago and always felt overheated. After using this product for a month, he now feels comfortable and has become more even-tempered, which suggests a positive effect on his liver health.
Read More
8.8
Improved liver indicators
Using milk thistle extract has substantially improved my liver function. I've noticed better indicators, including an increase in platelets and leukocytes. This extract is particularly beneficial for fatty liver issues and is also advantageous for those dealing with obesity-related diabetes and metabolic syndrome.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 8 Researches
7.9
- All Researches
9
Silybum marianum shows potential benefits
We examined a new oral supplement that combines prebiotics, yeast β-glucans, minerals, and Silybum marianum to see how it impacts obesity. Using a controlled study with mice, we found that this combination significantly improved energy balance and reduced inflammation.
After 28 days of treatment, mice on a high-fat diet showed lower blood sugar and fat levels, along with reduced liver damage indicators. While these findings are promising, it's essential to continue research to confirm these effects in humans.
After 28 days of treatment, mice on a high-fat diet showed lower blood sugar and fat levels, along with reduced liver damage indicators. While these findings are promising, it's essential to continue research to confirm these effects in humans.
Read More
8
Milk thistle extract may aid obesity
We explored the potential of a silymarin-enriched extract from milk thistle to aid in managing obesity and related inflammation. This study tested the extract's effect on activating thermogenesis in a model of obesity induced by a high-fat diet.
Our findings suggest that the extract helps enhance the body's ability to burn fat, which may be beneficial in preventing metabolic diseases and promoting healthy aging. However, the effectiveness of this treatment as a solution for obesity warrants further investigation.
Our findings suggest that the extract helps enhance the body's ability to burn fat, which may be beneficial in preventing metabolic diseases and promoting healthy aging. However, the effectiveness of this treatment as a solution for obesity warrants further investigation.
Read More
8
We explored how silymarin helps with obesity and muscle atrophy in mice. In our study, we divided the mice into three groups: a control group on a normal diet, another group on a high-fat diet, and a third group receiving silymarin alongside the high-fat diet.
The results showed that the silymarin group had less weight gain and maintained better muscle mass compared to the high-fat diet group. Moreover, the grip strength of the mice on silymarin improved. Overall, silymarin seems beneficial for not only tackling obesity but also preserving muscle health.
The results showed that the silymarin group had less weight gain and maintained better muscle mass compared to the high-fat diet group. Moreover, the grip strength of the mice on silymarin improved. Overall, silymarin seems beneficial for not only tackling obesity but also preserving muscle health.
Read More
8
Our investigation focused on how dietary milk thistle seeds and seed oil impact obesity-related intestinal, liver, and lipid issues, specifically in genetically obese rats. After five weeks, we found that rats supplemented with milk thistle seeds showed more significant improvements in liver fat and cholesterol levels compared to those receiving seed oil.
Notably, the seed group experienced better outcomes in their cecal short-chain fatty acid (SCFA) levels, indicating enhanced gut fermentation. Overall, milk thistle seeds appear to be more effective than oil in tackling obesity-related health challenges in these rats.
Notably, the seed group experienced better outcomes in their cecal short-chain fatty acid (SCFA) levels, indicating enhanced gut fermentation. Overall, milk thistle seeds appear to be more effective than oil in tackling obesity-related health challenges in these rats.
Read More
8
We investigated how milk thistle cold press oil (MTO) influences obesity and related health problems. In a study with mice on a high-fat diet, MTO was given for the last eight weeks. We found that MTO effectively reduced obesity, high blood sugar, and hypertension, while promoting healthier fat cell functions.
Additionally, MTO helped lower inflammation in both fat and liver tissues, and improved liver health as well. These positive outcomes suggest that MTO may be a valuable addition to the diets of those dealing with obesity and its complications.
Additionally, MTO helped lower inflammation in both fat and liver tissues, and improved liver health as well. These positive outcomes suggest that MTO may be a valuable addition to the diets of those dealing with obesity and its complications.
Read More
User Reviews
USERS' SCORE
Good
Based on 2 Reviews
8.5
- All Reviews
- Positive Reviews
- Negative Reviews
8
Positive liver results
I found this product very helpful for my family, as it has numerous benefits: it aids in the regeneration of liver cells and protects the liver from harmful substances like alcohol and cigarette smoke. It regulates bilirubin, enhances bile secretion, and improves skin conditions related to the liver. Unfortunately, I experienced an allergic reaction to turmeric in the formulation and opted for a different milk thistle product. However, my husband has had excellent results. He was diagnosed with liver obesity years ago and always felt overheated. After using this product for a month, he now feels comfortable and has become more even-tempered, which suggests a positive effect on his liver health.
Read More
8.8
Improved liver indicators
Using milk thistle extract has substantially improved my liver function. I've noticed better indicators, including an increase in platelets and leukocytes. This extract is particularly beneficial for fatty liver issues and is also advantageous for those dealing with obesity-related diabetes and metabolic syndrome.
Read More
Frequently Asked Questions
No FAQs are available for this product and symptom.
References
- Reguero M, Reglero G, Quintela JC, Ramos-Ruiz R, Ramírez de Molina A, et al. Silymarin-Enriched Extract from Milk Thistle Activates Thermogenesis in a Preclinical Model of High-Fat-Diet-Induced Obesity to Relieve Systemic Meta-Inflammation. Nutrients. 2024;16. doi:10.3390/nu16234166
- Santamarina AB, de Freitas JA, Franco LAM, Nehmi-Filho V, Fonseca JV, et al. Nutraceutical blends predict enhanced health via microbiota reshaping improving cytokines and life quality: a Brazilian double-blind randomized trial. Sci Rep. 2024;14:11127. doi:10.1038/s41598-024-61909-3
- Nehmi-Filho V, Santamarina AB, de Freitas JA, Trarbach EB, de Oliveira DR, et al. Novel nutraceutical supplements with yeast β-glucan, prebiotics, minerals, and (silymarin) ameliorate obesity-related metabolic and clinical parameters: A double-blind randomized trial. Front Endocrinol (Lausanne). 2022;13:1089938. doi:10.3389/fendo.2022.1089938
- Kim S, You Y, Kim OK, Lee J, Chung JW, et al. Silymarin Prevents High-Fat Diet-Induced Muscle Atrophy by Regulating Protein Degradation and Synthesis in Mice. J Med Food. 2022;25:793. doi:10.1089/jmf.2021.K.0175
- Opyd PM, Jurgoński A. Intestinal, liver and lipid disorders in genetically obese rats are more efficiently reduced by dietary milk thistle seeds than their oil. Sci Rep. 2021;11:20895. doi:10.1038/s41598-021-00397-1
- Nehmi VA, Murata GM, Moraes RCM, Lima GCA, De Miranda DA, et al. A novel supplement with yeast β-glucan, prebiotic, minerals and Silybum marianum synergistically modulates metabolic and inflammatory pathways and improves steatosis in obese mice. J Integr Med. 2021;19:439. doi:10.1016/j.joim.2021.05.002
- Shen HH, Alex R, Bellner L, Raffaele M, Licari M, et al. Milk thistle seed cold press oil attenuates markers of the metabolic syndrome in a mouse model of dietary-induced obesity. J Food Biochem. 2020;44:e13522. doi:10.1111/jfbc.13522
- Guarino G, Strollo F, Carbone L, Della Corte T, Letizia M, et al. Bioimpedance analysis, metabolic effects and safety of the association Berberis aristata/Bilybum marianum: a 52-week double-blind, placebo-controlled study in obese patients with type 2 diabetes. J Biol Regul Homeost Agents. 2017;31:495.
