Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 6 Researches
7.3
USERS' SCORE
Good
Based on 44 Reviews
8.3
Supplement Facts
Serving Size: 1/2 Level Teaspoon (approx. 1.9 g)
Amount Per Serving
%DV
Vitamin C (from Sodium Ascorbate)
1.67 g (1,670 mg
1856%
Sodium (from Sodium Ascorbate)
210 mg
9%
Top Medical Research Studies
8
We examined the effects of vitamin C on pneumonia caused by the influenza virus, specifically the H1N1 strain, in mice under stress. The study found that when exposed to restraint stress, the mice experienced increased mortality and more severe pneumonia symptoms.
However, by giving them oral vitamin C at doses of 125 and 250 mg/kg, we observed a significant reduction in these severe outcomes. Vitamin C seemed to modulate the expression of certain genes related to the immune response, such as MAVS and IRF3, and increased the expression of NF-κB, which plays a key role in the body's antiviral defense.
Our research suggested that vitamin C's protective effects might stem from its ability to inhibit excess cortisol production in the adrenal gland, which is often elevated due to stress. By lowering cortisol levels, vitamin C may help reduce susceptibility to influenza infections, making it a potential ally during the flu season, especially for those experiencing stress.
Through these findings, we highlighted a new mechanism for how vitamin C can be beneficial during influenza infections, particularly for those who are feeling overwhelmed.
However, by giving them oral vitamin C at doses of 125 and 250 mg/kg, we observed a significant reduction in these severe outcomes. Vitamin C seemed to modulate the expression of certain genes related to the immune response, such as MAVS and IRF3, and increased the expression of NF-κB, which plays a key role in the body's antiviral defense.
Our research suggested that vitamin C's protective effects might stem from its ability to inhibit excess cortisol production in the adrenal gland, which is often elevated due to stress. By lowering cortisol levels, vitamin C may help reduce susceptibility to influenza infections, making it a potential ally during the flu season, especially for those experiencing stress.
Through these findings, we highlighted a new mechanism for how vitamin C can be beneficial during influenza infections, particularly for those who are feeling overwhelmed.
Read More
8
We examined the effects of high doses of Vitamin C on preventing and alleviating cold and flu symptoms in a controlled study involving 715 students.
The test group received 1000 mg doses of Vitamin C when symptoms appeared, while the control group used standard pain relievers.
Our findings suggested that Vitamin C seemed to help relieve these symptoms better than the treatments used for the control group, showing potential benefits for managing flu and cold symptoms.
The test group received 1000 mg doses of Vitamin C when symptoms appeared, while the control group used standard pain relievers.
Our findings suggested that Vitamin C seemed to help relieve these symptoms better than the treatments used for the control group, showing potential benefits for managing flu and cold symptoms.
Read More
8
Vitamin C triterpene flu inhibitors
We recently explored the potential of novel compounds that are combinations of L-ascorbic acid, commonly known as vitamin C, and pentacyclic triterpenes in battling the flu. The study focused on compounds we created and tested against the influenza virus in MDCK cells, particularly looking at their effectiveness and any possible side effects.
Among all the compounds we evaluated, one stood out: the 2,3-O,O-dibenzyl-6-deoxy-L-ascorbic acid-betulinic acid conjugate. It displayed significant anti-influenza activity with an effective concentration (EC50) of just 8.7 μM and was not toxic to the cells used in our testing. This suggests that combining vitamin C with these triterpenes might enhance their ability to fight the flu virus, marking an exciting avenue for further research.
We also discovered that this particular compound acts early in the influenza lifecycle, interfering with the virus's ability to attach to cells. We confirmed this by observing that it inhibited the hemagglutination—a crucial step that allows the virus to spread. Our findings indicate that L-ascorbic acid-conjugated triterpenes hold promise as potential anti-influenza agents, specifically targeting viral entry and enhancing the effectiveness of treatment strategies.
Among all the compounds we evaluated, one stood out: the 2,3-O,O-dibenzyl-6-deoxy-L-ascorbic acid-betulinic acid conjugate. It displayed significant anti-influenza activity with an effective concentration (EC50) of just 8.7 μM and was not toxic to the cells used in our testing. This suggests that combining vitamin C with these triterpenes might enhance their ability to fight the flu virus, marking an exciting avenue for further research.
We also discovered that this particular compound acts early in the influenza lifecycle, interfering with the virus's ability to attach to cells. We confirmed this by observing that it inhibited the hemagglutination—a crucial step that allows the virus to spread. Our findings indicate that L-ascorbic acid-conjugated triterpenes hold promise as potential anti-influenza agents, specifically targeting viral entry and enhancing the effectiveness of treatment strategies.
Read More
Most Useful Reviews
9
Immune boost
24 people found this helpful
I've been taking this vitamin C daily for about a month and haven't fallen ill at all! Typically, I experience seasonal colds, yet this year I only faced a mild sniffle. Everyone around me caught various bugs, but I maintained my health even with a newborn needing care. It's remarkable how this easily absorbed vitamin C can bolster the immune system, helping to prevent illnesses like the flu.
Read More
9
Illness prevention
15 people found this helpful
I give this to myself, my husband, and our 4-month-old daily, and we have successfully avoided sickness throughout the cold and flu season thus far. It’s a reliable preventative measure that I highly recommend.
Read More
9
Universal prevention
2 people found this helpful
Vitamin C in sodium ascorbate form is universal for preventing viral infections. With a pH of 7.1, it's gentle on those with gastritis and can be taken by pregnant women and children. It is particularly effective for colds and respiratory diseases like SARS and flu.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 6 Researches
7.3
- All Researches
9
We set out to discover how red ginseng and vitamin C work together to enhance immune cell function and fight off viral infections like the flu. In our investigation, we treated human immune cells and specific types of mice unable to produce vitamin C, looking closely at their reaction to influenza A virus/H1N1.
Our findings were quite promising. We observed that both red ginseng and vitamin C elevated the activation levels of immune cells, particularly T-cells and natural killer (NK) cells, known for their vital role in combating viruses. This combination not only helped boost immune cell activity but also reduced lung inflammation caused by the influenza virus, which is crucial for better survival rates during infections.
In cases where vitamin C levels were low in a specific mouse model, we noted that the added nutrients significantly improved their condition. They experienced reduced viral load and inflammation in their lungs after receiving red ginseng and vitamin C, compared to those without this supplementation. These insights suggest that while red ginseng and vitamin C collectively support immune health, the interplay of these substances can be crucial in managing flu infections effectively.
Our findings were quite promising. We observed that both red ginseng and vitamin C elevated the activation levels of immune cells, particularly T-cells and natural killer (NK) cells, known for their vital role in combating viruses. This combination not only helped boost immune cell activity but also reduced lung inflammation caused by the influenza virus, which is crucial for better survival rates during infections.
In cases where vitamin C levels were low in a specific mouse model, we noted that the added nutrients significantly improved their condition. They experienced reduced viral load and inflammation in their lungs after receiving red ginseng and vitamin C, compared to those without this supplementation. These insights suggest that while red ginseng and vitamin C collectively support immune health, the interplay of these substances can be crucial in managing flu infections effectively.
Read More
8
We examined the effects of high doses of Vitamin C on preventing and alleviating cold and flu symptoms in a controlled study involving 715 students.
The test group received 1000 mg doses of Vitamin C when symptoms appeared, while the control group used standard pain relievers.
Our findings suggested that Vitamin C seemed to help relieve these symptoms better than the treatments used for the control group, showing potential benefits for managing flu and cold symptoms.
The test group received 1000 mg doses of Vitamin C when symptoms appeared, while the control group used standard pain relievers.
Our findings suggested that Vitamin C seemed to help relieve these symptoms better than the treatments used for the control group, showing potential benefits for managing flu and cold symptoms.
Read More
8
Vitamin C triterpene flu inhibitors
We recently explored the potential of novel compounds that are combinations of L-ascorbic acid, commonly known as vitamin C, and pentacyclic triterpenes in battling the flu. The study focused on compounds we created and tested against the influenza virus in MDCK cells, particularly looking at their effectiveness and any possible side effects.
Among all the compounds we evaluated, one stood out: the 2,3-O,O-dibenzyl-6-deoxy-L-ascorbic acid-betulinic acid conjugate. It displayed significant anti-influenza activity with an effective concentration (EC50) of just 8.7 μM and was not toxic to the cells used in our testing. This suggests that combining vitamin C with these triterpenes might enhance their ability to fight the flu virus, marking an exciting avenue for further research.
We also discovered that this particular compound acts early in the influenza lifecycle, interfering with the virus's ability to attach to cells. We confirmed this by observing that it inhibited the hemagglutination—a crucial step that allows the virus to spread. Our findings indicate that L-ascorbic acid-conjugated triterpenes hold promise as potential anti-influenza agents, specifically targeting viral entry and enhancing the effectiveness of treatment strategies.
Among all the compounds we evaluated, one stood out: the 2,3-O,O-dibenzyl-6-deoxy-L-ascorbic acid-betulinic acid conjugate. It displayed significant anti-influenza activity with an effective concentration (EC50) of just 8.7 μM and was not toxic to the cells used in our testing. This suggests that combining vitamin C with these triterpenes might enhance their ability to fight the flu virus, marking an exciting avenue for further research.
We also discovered that this particular compound acts early in the influenza lifecycle, interfering with the virus's ability to attach to cells. We confirmed this by observing that it inhibited the hemagglutination—a crucial step that allows the virus to spread. Our findings indicate that L-ascorbic acid-conjugated triterpenes hold promise as potential anti-influenza agents, specifically targeting viral entry and enhancing the effectiveness of treatment strategies.
Read More
8
We examined the effects of vitamin C on pneumonia caused by the influenza virus, specifically the H1N1 strain, in mice under stress. The study found that when exposed to restraint stress, the mice experienced increased mortality and more severe pneumonia symptoms.
However, by giving them oral vitamin C at doses of 125 and 250 mg/kg, we observed a significant reduction in these severe outcomes. Vitamin C seemed to modulate the expression of certain genes related to the immune response, such as MAVS and IRF3, and increased the expression of NF-κB, which plays a key role in the body's antiviral defense.
Our research suggested that vitamin C's protective effects might stem from its ability to inhibit excess cortisol production in the adrenal gland, which is often elevated due to stress. By lowering cortisol levels, vitamin C may help reduce susceptibility to influenza infections, making it a potential ally during the flu season, especially for those experiencing stress.
Through these findings, we highlighted a new mechanism for how vitamin C can be beneficial during influenza infections, particularly for those who are feeling overwhelmed.
However, by giving them oral vitamin C at doses of 125 and 250 mg/kg, we observed a significant reduction in these severe outcomes. Vitamin C seemed to modulate the expression of certain genes related to the immune response, such as MAVS and IRF3, and increased the expression of NF-κB, which plays a key role in the body's antiviral defense.
Our research suggested that vitamin C's protective effects might stem from its ability to inhibit excess cortisol production in the adrenal gland, which is often elevated due to stress. By lowering cortisol levels, vitamin C may help reduce susceptibility to influenza infections, making it a potential ally during the flu season, especially for those experiencing stress.
Through these findings, we highlighted a new mechanism for how vitamin C can be beneficial during influenza infections, particularly for those who are feeling overwhelmed.
Read More
7
We examined how vitamin C supplementation can impact flu incidence and symptom duration. Our analysis of clinical studies indicated that vitamin C does show promise in reducing the risk of acute respiratory infections, including flu. Specifically, vitamin C reduced the likelihood of catching an acute respiratory infection by approximately 4% (risk ratio of 0.96).
Additionally, we observed that vitamin C also helps shorten the duration of flu symptoms by around 9%. This effect seemed to be more pronounced in men and people from middle-income countries, highlighting the complexity of health factors influenced by gender and socio-economic status.
Overall, while the findings suggest vitamin C can be a modicum of hope in managing flu symptoms, it isn't a standalone solution. Our results advocate for more research to fully understand the impact of vitamin C, especially in the context of the ongoing challenges posed by various respiratory viruses, including influenza.
Additionally, we observed that vitamin C also helps shorten the duration of flu symptoms by around 9%. This effect seemed to be more pronounced in men and people from middle-income countries, highlighting the complexity of health factors influenced by gender and socio-economic status.
Overall, while the findings suggest vitamin C can be a modicum of hope in managing flu symptoms, it isn't a standalone solution. Our results advocate for more research to fully understand the impact of vitamin C, especially in the context of the ongoing challenges posed by various respiratory viruses, including influenza.
Read More
User Reviews
USERS' SCORE
Good
Based on 44 Reviews
8.3
- All Reviews
- Positive Reviews
- Negative Reviews
9
Immune boost
24 people found this helpful
I've been taking this vitamin C daily for about a month and haven't fallen ill at all! Typically, I experience seasonal colds, yet this year I only faced a mild sniffle. Everyone around me caught various bugs, but I maintained my health even with a newborn needing care. It's remarkable how this easily absorbed vitamin C can bolster the immune system, helping to prevent illnesses like the flu.
Read More
9
Illness prevention
15 people found this helpful
I give this to myself, my husband, and our 4-month-old daily, and we have successfully avoided sickness throughout the cold and flu season thus far. It’s a reliable preventative measure that I highly recommend.
Read More
9
Universal prevention
2 people found this helpful
Vitamin C in sodium ascorbate form is universal for preventing viral infections. With a pH of 7.1, it's gentle on those with gastritis and can be taken by pregnant women and children. It is particularly effective for colds and respiratory diseases like SARS and flu.
Read More
10
Saviour during sickness
This powder has saved my family during colds, flu, and SARS time and again! A mere half a teaspoon transforms your morning; the only downside is its taste, which is manageable when mixed with juice. I highly recommend it!
Read More
10
Improved immune health
WIN WIN! I’ve taken this daily for about a month. Previously, I would frequently get sick, but now I haven't fallen ill at all! This year, I've only had a minor sniffle while those around me caught various bugs. Build your immune system with this easily absorbed Vitamin C!
Read More
Frequently Asked Questions
9
Lifesaver for colds
An excellent helper for colds! This isn’t my first order; it’s a lifesaver. On many occasions, when I’ve sensed a cold coming on, I've pulled through in just 1-2 days. If taken on time, you won’t fall ill at all. I also recommend pairing it with zinc and vitamin D for better effects during cold and flu season.
9
Highly effective remedy
This powder has saved my family during colds, flu, and SARS! It's irreplaceable! A half teaspoon of magic powder and I feel as good as new by morning! The only minor downside is its taste, which is tolerable. Even children enjoy it with juice or compote! I recommend it—stay healthy!
9
No more colds
Since consistently using this vitamin C product, I haven't truly suffered from any significant colds or flu. It outperforms other over-the-counter options.
10
Improved immune health
WIN WIN! I’ve taken this daily for about a month. Previously, I would frequently get sick, but now I haven't fallen ill at all! This year, I've only had a minor sniffle while those around me caught various bugs. Build your immune system with this easily absorbed Vitamin C!
9
Natural immunity booster
This buffered vitamin C is effective for colds and flu, improves immunity, and does not irritate the stomach. We use it as a family during colds and find it improves our health significantly. The quality is excellent, and it comes in convenient packaging.
7.5
Family health support
Sodium ascorbate is the buffered form of vitamin C and highly effective. At the first signs of a cold or flu, my whole family starts taking it. We increase the dose to 5-6 grams per day for maximum effect, taking it every 2-3 hours. Diluting it in juice makes it easier for the children to drink, and it's economical enough for six months. This form is safe for the stomach; I recommend it to everyone.
9
Promotes recovery
This is my go-to when I require extra vitamin C. When I have the flu, I take 2 tablespoons in water every 2-4 hours to foster recovery.
10
Saviour during sickness
This powder has saved my family during colds, flu, and SARS time and again! A mere half a teaspoon transforms your morning; the only downside is its taste, which is manageable when mixed with juice. I highly recommend it!
References
- Gorton HC, Jarvis K. The effectiveness of vitamin C in preventing and relieving the symptoms of virus-induced respiratory infections. J Manipulative Physiol Ther. 1999;22:530.
- Abioye AI, Bromage S, Fawzi W. Effect of micronutrient supplements on influenza and other respiratory tract infections among adults: a systematic review and meta-analysis. BMJ Glob Health. 2021;6. doi:10.1136/bmjgh-2020-003176
- Márquez-Domínguez L, Reyes-Leyva J, Herrera-Camacho I, Santos-López G, Scior T. Five Novel Non-Sialic Acid-Like Scaffolds Inhibit In Vitro H1N1 and H5N2 Neuraminidase Activity of Influenza a Virus. Molecules. 2020;25. doi:10.3390/molecules25184248
- Kim H, Jang M, Kim Y, Choi J, Jeon J, et al. Red ginseng and vitamin C increase immune cell activity and decrease lung inflammation induced by influenza A virus/H1N1 infection. J Pharm Pharmacol. 2016;68:406. doi:10.1111/jphp.12529
- Wang H, Xu R, Shi Y, Si L, Jiao P, et al. Design, synthesis and biological evaluation of novel L-ascorbic acid-conjugated pentacyclic triterpene derivatives as potential influenza virus entry inhibitors. Eur J Med Chem. 2016;110:376. doi:10.1016/j.ejmech.2016.01.005
- Cai Y, Li YF, Tang LP, Tsoi B, Chen M, et al. A new mechanism of vitamin C effects on A/FM/1/47(H1N1) virus-induced pneumonia in restraint-stressed mice. Biomed Res Int. 2015;2015:675149. doi:10.1155/2015/675149
