Last update
5/5/2026
Reviewed By
Overview
SCIENTIFIC SCORE
Very Likely Ineffective
Based on 1 Research
0
USERS' SCORE
Good
Based on 11 Reviews
8.1
Supplement Facts
Serving Size: 1 Veg Capsule
Amount Per Serving
%DV
5-HTP (5-hydroxytryptophan) (from Griffonia simplicifolia Extract) (Seed)
100 mg
*
Top Medical Research Studies
0
5-HTP ineffective for hot flashes
We aimed to find out how effective 5-hydroxytryptophan (5-HTP) is for reducing hot flashes in menopausal women.
In a double-blind study involving 24 postmenopausal participants, we divided the group to receive either 5-HTP or a placebo.
Unfortunately, our results showed no significant difference in hot flash frequency between the two groups after treatment.
Thus, it appears that 5-HTP at the tested dose does not effectively alleviate hot flashes, making further research necessary.
In a double-blind study involving 24 postmenopausal participants, we divided the group to receive either 5-HTP or a placebo.
Unfortunately, our results showed no significant difference in hot flash frequency between the two groups after treatment.
Thus, it appears that 5-HTP at the tested dose does not effectively alleviate hot flashes, making further research necessary.
Read More
Most Useful Reviews
9
Normal sleep restored
1 people found this helpful
It greatly alleviates anxious sleep; I used to awaken several times during the night due to menopause. With 5-HTP, my sleep has gradually returned to normal, and now I rest undisturbed until morning.
Read More
9
Effective for edge
1 people found this helpful
The combined use of 5-HTP and GABA effectively smooths the impact of menopause. Without it, I would surely be overwhelmed. Give it a try; it truly works wonders.
Read More
9
Stable mood
1 people found this helpful
This product has been excellent during menopause. I have been using it for several months and will continue to do so. My mood has stabilised significantly, and I no longer feel irritable. I take two capsules daily and have no sleep issues.
Read More
Medical Researches
SCIENTIFIC SCORE
Very Likely Ineffective
Based on 1 Research
0
- All Researches
0
5-HTP ineffective for hot flashes
We aimed to find out how effective 5-hydroxytryptophan (5-HTP) is for reducing hot flashes in menopausal women.
In a double-blind study involving 24 postmenopausal participants, we divided the group to receive either 5-HTP or a placebo.
Unfortunately, our results showed no significant difference in hot flash frequency between the two groups after treatment.
Thus, it appears that 5-HTP at the tested dose does not effectively alleviate hot flashes, making further research necessary.
In a double-blind study involving 24 postmenopausal participants, we divided the group to receive either 5-HTP or a placebo.
Unfortunately, our results showed no significant difference in hot flash frequency between the two groups after treatment.
Thus, it appears that 5-HTP at the tested dose does not effectively alleviate hot flashes, making further research necessary.
Read More
User Reviews
USERS' SCORE
Good
Based on 11 Reviews
8.1
- All Reviews
- Positive Reviews
- Negative Reviews
9
Normal sleep restored
1 people found this helpful
It greatly alleviates anxious sleep; I used to awaken several times during the night due to menopause. With 5-HTP, my sleep has gradually returned to normal, and now I rest undisturbed until morning.
Read More
9
Effective for edge
1 people found this helpful
The combined use of 5-HTP and GABA effectively smooths the impact of menopause. Without it, I would surely be overwhelmed. Give it a try; it truly works wonders.
Read More
9
Stable mood
1 people found this helpful
This product has been excellent during menopause. I have been using it for several months and will continue to do so. My mood has stabilised significantly, and I no longer feel irritable. I take two capsules daily and have no sleep issues.
Read More
9
Improved mood
I am 47 years old and experiencing menopause. I've had mood swings, nervousness, and insomnia. Since taking these vitamins, I've begun to feel more normal. Initially, I took them twice daily—morning on an empty stomach and evening before bed. Now, I only take them in the evening, which helps my mood and calmness. If I take them in the morning, I'm in a great mood with no nerves. In the evening, I sleep peacefully without racing thoughts. I also noticed my hair dye appears darker, likely due to melatonin. I find I’m not craving food, smoking, or drinking as I used to. I've also sent two packages to my sister in Ukraine.
Read More
7.5
Positive mood shift
40 people found this helpful
Pretty good! During menopause, I was feeling stressed and depressed, so I tried it hesitantly. It has truly helped—I don’t feel down or particularly up, but my body feels lighter. I was previously lazy and struggled with housework, but now I can manage it effortlessly. Most importantly, my negative thoughts seem to have vanished. I would like to continue using it.
Read More
Frequently Asked Questions
9
Stable mood
1 people found this helpful
This product has been excellent during menopause. I have been using it for several months and will continue to do so. My mood has stabilised significantly, and I no longer feel irritable. I take two capsules daily and have no sleep issues.
9
Improved mood
I am 47 years old and experiencing menopause. I've had mood swings, nervousness, and insomnia. Since taking these vitamins, I've begun to feel more normal. Initially, I took them twice daily—morning on an empty stomach and evening before bed. Now, I only take them in the evening, which helps my mood and calmness. If I take them in the morning, I'm in a great mood with no nerves. In the evening, I sleep peacefully without racing thoughts. I also noticed my hair dye appears darker, likely due to melatonin. I find I’m not craving food, smoking, or drinking as I used to. I've also sent two packages to my sister in Ukraine.
7.5
Insolvable insomnia
A fantastic remedy for insomnia linked to hormonal changes during menopause. Everyone's experience is different, but through my use, I’ve found it to be truly beneficial. Highly recommend giving it a go!
9
Normal sleep restored
1 people found this helpful
It greatly alleviates anxious sleep; I used to awaken several times during the night due to menopause. With 5-HTP, my sleep has gradually returned to normal, and now I rest undisturbed until morning.
7.5
Positive mood shift
40 people found this helpful
Pretty good! During menopause, I was feeling stressed and depressed, so I tried it hesitantly. It has truly helped—I don’t feel down or particularly up, but my body feels lighter. I was previously lazy and struggled with housework, but now I can manage it effortlessly. Most importantly, my negative thoughts seem to have vanished. I would like to continue using it.
9
Effective for edge
1 people found this helpful
The combined use of 5-HTP and GABA effectively smooths the impact of menopause. Without it, I would surely be overwhelmed. Give it a try; it truly works wonders.
7.5
Improved sleep quality
2 people found this helpful
I’m 45 and have been dealing with menopause for 7 years, experiencing mood swings and poor sleep. This medicine has really helped me establish a good sleep pattern. I take it every three days in the afternoon, which is sufficient for me. Now, I fall asleep well and wake up refreshed, with a stable mood. This medication has truly benefitted me, and I wish the same for you.
6
Helped with moods
2 people found this helpful
I take one pill every night before bed. It significantly aids my mood during menopause. I once forgot a dose and felt extremely anxious the next morning. Since then, I ensure I never skip it.
0
5-HTP ineffective for hot flashes
We aimed to find out how effective 5-hydroxytryptophan (5-HTP) is for reducing hot flashes in menopausal women.
In a double-blind study involving 24 postmenopausal participants, we divided the group to receive either 5-HTP or a placebo.
Unfortunately, our results showed no significant difference in hot flash frequency between the two groups after treatment.
Thus, it appears that 5-HTP at the tested dose does not effectively alleviate hot flashes, making further research necessary.
In a double-blind study involving 24 postmenopausal participants, we divided the group to receive either 5-HTP or a placebo.
Unfortunately, our results showed no significant difference in hot flash frequency between the two groups after treatment.
Thus, it appears that 5-HTP at the tested dose does not effectively alleviate hot flashes, making further research necessary.
References
- Freedman RR. Treatment of menopausal hot flashes with 5-hydroxytryptophan. Maturitas. 2010;65:383. 10.1016/j.maturitas.2009.11.025
