Last update
3/16/2026
Reviewed By
Overview
SCIENTIFIC SCORE
Very Likely Ineffective
Based on 1 Research
0
USERS' SCORE
Good
Based on 9 Reviews
8.3
Supplement Facts
Serving Size: 1 Veg Capsule
Amount Per Serving
%DV
5-HTP (5-hydroxytryptophan) (from Griffonia simplicifolia Extract) (seed)
50 mg
*
Top Medical Research Studies
0
5-HTP ineffective for hot flashes
We aimed to find out how effective 5-hydroxytryptophan (5-HTP) is for reducing hot flashes in menopausal women.
In a double-blind study involving 24 postmenopausal participants, we divided the group to receive either 5-HTP or a placebo.
Unfortunately, our results showed no significant difference in hot flash frequency between the two groups after treatment.
Thus, it appears that 5-HTP at the tested dose does not effectively alleviate hot flashes, making further research necessary.
In a double-blind study involving 24 postmenopausal participants, we divided the group to receive either 5-HTP or a placebo.
Unfortunately, our results showed no significant difference in hot flash frequency between the two groups after treatment.
Thus, it appears that 5-HTP at the tested dose does not effectively alleviate hot flashes, making further research necessary.
Read More
Most Useful Reviews
9
Calms nervousness
I recommend it! I purchased this dietary supplement and am very pleased; it is my salvation! I have menopause and increased nervousness. Taking 5-NTR together with magnesium has made me much calmer and helped eliminate the nervousness. The quality is excellent, and the size is convenient to take; there are definitely benefits!
Read More
9
Improves sleep quality
Thank you for the informative reviews! This supplement really helped with restless sleep, symptoms of menopause, and appetite reduction. The small capsules are tasteless and odourless, contributing positively to my health!
Read More
9
Enhances mood support
It positively affects sleep and mood swings, acting as a source of serotonin, the joy hormone. It helps me manage menopause. After taking it for two months, I am calmer, sleep well, and my anxiety has disappeared. An excellent tool!
Read More
Medical Researches
SCIENTIFIC SCORE
Very Likely Ineffective
Based on 1 Research
0
- All Researches
0
5-HTP ineffective for hot flashes
We aimed to find out how effective 5-hydroxytryptophan (5-HTP) is for reducing hot flashes in menopausal women.
In a double-blind study involving 24 postmenopausal participants, we divided the group to receive either 5-HTP or a placebo.
Unfortunately, our results showed no significant difference in hot flash frequency between the two groups after treatment.
Thus, it appears that 5-HTP at the tested dose does not effectively alleviate hot flashes, making further research necessary.
In a double-blind study involving 24 postmenopausal participants, we divided the group to receive either 5-HTP or a placebo.
Unfortunately, our results showed no significant difference in hot flash frequency between the two groups after treatment.
Thus, it appears that 5-HTP at the tested dose does not effectively alleviate hot flashes, making further research necessary.
Read More
User Reviews
USERS' SCORE
Good
Based on 9 Reviews
8.3
- All Reviews
- Positive Reviews
- Negative Reviews
9
Calms nervousness
I recommend it! I purchased this dietary supplement and am very pleased; it is my salvation! I have menopause and increased nervousness. Taking 5-NTR together with magnesium has made me much calmer and helped eliminate the nervousness. The quality is excellent, and the size is convenient to take; there are definitely benefits!
Read More
9
Improves sleep quality
Thank you for the informative reviews! This supplement really helped with restless sleep, symptoms of menopause, and appetite reduction. The small capsules are tasteless and odourless, contributing positively to my health!
Read More
9
Enhances mood support
It positively affects sleep and mood swings, acting as a source of serotonin, the joy hormone. It helps me manage menopause. After taking it for two months, I am calmer, sleep well, and my anxiety has disappeared. An excellent tool!
Read More
8
Eases anxiety and depression
Experiencing insomnia during peri-menopause triggered my anxiety and depression. My doctor prescribed 5-HTP to relieve these issues. I can now sleep better at night and feel happier most of the time.
Read More
7.5
Serotonin boost
This product helps increase serotonin, enhancing disposition, reducing anxiety, and alleviating symptoms of menopause.
Read More
Frequently Asked Questions
9
Enhances mood support
It positively affects sleep and mood swings, acting as a source of serotonin, the joy hormone. It helps me manage menopause. After taking it for two months, I am calmer, sleep well, and my anxiety has disappeared. An excellent tool!
8
Eases anxiety and depression
Experiencing insomnia during peri-menopause triggered my anxiety and depression. My doctor prescribed 5-HTP to relieve these issues. I can now sleep better at night and feel happier most of the time.
9
Calms nervousness
I recommend it! I purchased this dietary supplement and am very pleased; it is my salvation! I have menopause and increased nervousness. Taking 5-NTR together with magnesium has made me much calmer and helped eliminate the nervousness. The quality is excellent, and the size is convenient to take; there are definitely benefits!
7.5
Serotonin boost
This product helps increase serotonin, enhancing disposition, reducing anxiety, and alleviating symptoms of menopause.
7.5
Mood improvement
The gel caps are easy to swallow and work well alongside other supplements. I had to create my own menopause blend due to supply issues with my previous product, but I found everything needed at a great price on iherb.com!
0
5-HTP ineffective for hot flashes
We aimed to find out how effective 5-hydroxytryptophan (5-HTP) is for reducing hot flashes in menopausal women.
In a double-blind study involving 24 postmenopausal participants, we divided the group to receive either 5-HTP or a placebo.
Unfortunately, our results showed no significant difference in hot flash frequency between the two groups after treatment.
Thus, it appears that 5-HTP at the tested dose does not effectively alleviate hot flashes, making further research necessary.
In a double-blind study involving 24 postmenopausal participants, we divided the group to receive either 5-HTP or a placebo.
Unfortunately, our results showed no significant difference in hot flash frequency between the two groups after treatment.
Thus, it appears that 5-HTP at the tested dose does not effectively alleviate hot flashes, making further research necessary.
References
- Freedman RR. Treatment of menopausal hot flashes with 5-hydroxytryptophan. Maturitas. 2010;65:383. 10.1016/j.maturitas.2009.11.025
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