Last update
5/12/2026
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Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 16 Researches
7.9
USERS' SCORE
Good
Based on 8 Reviews
8.3
Supplement Facts
Serving Size: 1 Chewable Tablet
Amount Per Serving
%DV
Top Medical Research Studies
9
Lactobacillus shows promise against flu
We explored the effects of heat-killed Lactobacillus gasseri TMC0356 on mice infected with the flu virus. After 19 days of treatment, we observed improved clinical symptoms, reduced viral loads, and enhanced immune responses in the treated mice compared to controls. This suggests that Lactobacillus could bolster both gut and respiratory immunity against influenza. However, these exciting results are limited to animal studies, and further research in humans is needed to fully understand its benefits.
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We explored the impact of the probiotic Bifidobacterium lactis Probio-M8 on young children hospitalized for acute respiratory infections.
Sixty children received the probiotic, while another sixty received a placebo under a carefully controlled, double-blind setup.
The study suggested that this probiotic could be a natural way to manage respiratory infections, potentially reducing antibiotic use and hospitalization duration.
However, results indicate that further research is needed to solidify these benefits.
Sixty children received the probiotic, while another sixty received a placebo under a carefully controlled, double-blind setup.
The study suggested that this probiotic could be a natural way to manage respiratory infections, potentially reducing antibiotic use and hospitalization duration.
However, results indicate that further research is needed to solidify these benefits.
Read More
8
We examined how probiotics affect our immune system and their potential to reduce the incidence of flu-like symptoms. In a carefully controlled, double-blind trial, adult participants who frequently caught colds were given either a probiotic drink or a placebo for 12 weeks.
The results showed that those consuming probiotics experienced fewer upper respiratory infections and flu-like symptoms. They also displayed higher immune markers in their blood and gut. While probiotics proved effective overall, no significant differences were noted for other immune-related markers.
This highlights the potential of probiotics as a safe way to combat the common cold and flu.
The results showed that those consuming probiotics experienced fewer upper respiratory infections and flu-like symptoms. They also displayed higher immune markers in their blood and gut. While probiotics proved effective overall, no significant differences were noted for other immune-related markers.
This highlights the potential of probiotics as a safe way to combat the common cold and flu.
Read More
Most Useful Reviews
7.5
Effective flu solution
5 people found this helpful
Better Not Found Bye! The Most Useful Bacteria! Although gastroenterologists have differing opinions, I was fortunate to find a knowledgeable one who praised the benefits of probiotics. I discovered Streptococcus to be particularly effective, as advised by my doctor. We have been consuming it for a month and were pleasantly surprised by the results! During flu season, my child had been free from illness for six weeks, while I caught the virus twice. My child only experienced minor symptoms. When he eventually developed a cough, I increased his dosage along with vitamin C, zinc, and vitamin D, and he showed significant improvement, nearly eliminating his cough! I have also ordered the adult version for myself due to its impressive effects.
Read More
9
Probiotic benefits
3 people found this helpful
A probiotic my kids enjoy. My children love these! Even my one-year-old begs for them. Since she started taking these, there's been no constipation. I suspect they truly help with immunity; we had guests who brought the flu, yet my family never caught it, and we didn't even get the flu shot—we just take probiotics regularly.
Read More
9
Flu and allergy relief
I am utterly amazed at this product. Ever since my little girl (5 years old) started using it, she no longer suffers from the flu, and her allergy symptoms have decreased significantly. I plan to purchase more and hope the "Now" company continues to deliver such high-quality products!
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 16 Researches
7.9
- All Researches
9
We examined the impact of EpiCor, a yeast-derived postbiotic, on flu symptoms in healthy children. In a study involving 256 kids aged 4-12, participants took either EpiCor or a placebo for 84 days during the flu season.
The results were promising! Kids receiving EpiCor experienced significantly reduced severity of cold/flu symptoms and relied less on cold medications compared to those on the placebo. Overall, EpiCor proved to be a safe option for bolstering immune function in young children.
The results were promising! Kids receiving EpiCor experienced significantly reduced severity of cold/flu symptoms and relied less on cold medications compared to those on the placebo. Overall, EpiCor proved to be a safe option for bolstering immune function in young children.
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9
We conducted a study to see if probiotics could make a difference for flu-vaccinated elderly individuals. Fifty participants in a double-blind, placebo-controlled trial took a multistrain probiotic for 28 days.
After this period, we noticed a decrease in both symptoms and incidence of common infections in those who received the probiotics. Additionally, we found promising changes in immune system markers and gut health. This indicates that probiotics might improve protection against infections by boosting immunity and positively influencing gut microbiota.
After this period, we noticed a decrease in both symptoms and incidence of common infections in those who received the probiotics. Additionally, we found promising changes in immune system markers and gut health. This indicates that probiotics might improve protection against infections by boosting immunity and positively influencing gut microbiota.
Read More
9
Probiotics reduce flu-related costs
We explored how probiotics can reduce the health care costs and societal impacts of flu-like respiratory infections. By using a state-transition microsimulation model, we investigated various scenarios to estimate the economic benefits of probiotics in 2017-2018.
Our findings revealed potential savings of $4.6 million to $1.4 billion, depending on the source of data analyzed. Overall, fewer RTI episodes led to less medical intervention and fewer missed workdays.
While the results suggest probiotics could alleviate some burden on health systems, this study focuses mainly on economic modeling rather than direct clinical effectiveness.
Our findings revealed potential savings of $4.6 million to $1.4 billion, depending on the source of data analyzed. Overall, fewer RTI episodes led to less medical intervention and fewer missed workdays.
While the results suggest probiotics could alleviate some burden on health systems, this study focuses mainly on economic modeling rather than direct clinical effectiveness.
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9
Probiotics show promise against influenza
We investigated the potential of two recombinant probiotics, Lactobacillus plantarum NC8-409-1 and NC8-409-2, in preventing influenza in mice. These vaccines successfully triggered immune responses, notably increasing specific antibodies in both the intestine and serum.
Notably, NC8-409-2 demonstrated substantial protection against H9N2—up to 80%—while NC8-409-1 showed about 60% protection against H1N1. Although these results hint at exciting possibilities for developing oral vaccines against avian flu, the overall effectiveness against human flu is uncertain.
Notably, NC8-409-2 demonstrated substantial protection against H9N2—up to 80%—while NC8-409-1 showed about 60% protection against H1N1. Although these results hint at exciting possibilities for developing oral vaccines against avian flu, the overall effectiveness against human flu is uncertain.
Read More
9
Lactobacillus shows promise against flu
We explored the effects of heat-killed Lactobacillus gasseri TMC0356 on mice infected with the flu virus. After 19 days of treatment, we observed improved clinical symptoms, reduced viral loads, and enhanced immune responses in the treated mice compared to controls. This suggests that Lactobacillus could bolster both gut and respiratory immunity against influenza. However, these exciting results are limited to animal studies, and further research in humans is needed to fully understand its benefits.
Read More
User Reviews
USERS' SCORE
Good
Based on 8 Reviews
8.3
- All Reviews
- Positive Reviews
- Negative Reviews
7.5
Effective flu solution
5 people found this helpful
Better Not Found Bye! The Most Useful Bacteria! Although gastroenterologists have differing opinions, I was fortunate to find a knowledgeable one who praised the benefits of probiotics. I discovered Streptococcus to be particularly effective, as advised by my doctor. We have been consuming it for a month and were pleasantly surprised by the results! During flu season, my child had been free from illness for six weeks, while I caught the virus twice. My child only experienced minor symptoms. When he eventually developed a cough, I increased his dosage along with vitamin C, zinc, and vitamin D, and he showed significant improvement, nearly eliminating his cough! I have also ordered the adult version for myself due to its impressive effects.
Read More
9
Probiotic benefits
3 people found this helpful
A probiotic my kids enjoy. My children love these! Even my one-year-old begs for them. Since she started taking these, there's been no constipation. I suspect they truly help with immunity; we had guests who brought the flu, yet my family never caught it, and we didn't even get the flu shot—we just take probiotics regularly.
Read More
9
Flu and allergy relief
I am utterly amazed at this product. Ever since my little girl (5 years old) started using it, she no longer suffers from the flu, and her allergy symptoms have decreased significantly. I plan to purchase more and hope the "Now" company continues to deliver such high-quality products!
Read More
9
Resolves intestinal flu
My son has had intestinal issues since infancy, and this year he also suffered from intestinal flu. He took a long time to recover, and I was concerned it would never end. However, after using this probiotic, his intestinal problems disappeared, which I am incredibly pleased about. Thank you for this quality product!
Read More
9
Immunity building
1 people found this helpful
This product is excellent for children’s immunity. My child has not caught the flu since I started giving it. He has been healthier, and I will definitely repurchase it. Probiotics have significantly benefitted our children.
Read More
Frequently Asked Questions
7.5
Effective flu solution
5 people found this helpful
Better Not Found Bye! The Most Useful Bacteria! Although gastroenterologists have differing opinions, I was fortunate to find a knowledgeable one who praised the benefits of probiotics. I discovered Streptococcus to be particularly effective, as advised by my doctor. We have been consuming it for a month and were pleasantly surprised by the results! During flu season, my child had been free from illness for six weeks, while I caught the virus twice. My child only experienced minor symptoms. When he eventually developed a cough, I increased his dosage along with vitamin C, zinc, and vitamin D, and he showed significant improvement, nearly eliminating his cough! I have also ordered the adult version for myself due to its impressive effects.
9
Flu and allergy relief
I am utterly amazed at this product. Ever since my little girl (5 years old) started using it, she no longer suffers from the flu, and her allergy symptoms have decreased significantly. I plan to purchase more and hope the "Now" company continues to deliver such high-quality products!
References
- Al-Akel FC, Chiperi LE, Eszter VK, Bacârea A. Role as a Probiotic in Children's Health and Disease Prophylaxis-A Systematic Review. Life (Basel). 2024;14. 10.3390/life14121613
- Singh RG, Garcia-Campayo V, Green JB, Paton N, Saunders JD, et al. Efficacy of a yeast postbiotic on cold/flu symptoms in healthy children: A randomized-controlled trial. Pediatr Res. 2024;96:1739. 10.1038/s41390-024-03331-z
- Zhao Y, Dong BR, Hao Q. Probiotics for preventing acute upper respiratory tract infections. Cochrane Database Syst Rev. 2022;8:CD006895. 10.1002/14651858.CD006895.pub4
- Sandionigi A, De Giani A, Tursi F, Michelotti A, Cestone E, et al. Effectiveness of Multistrain Probiotic Formulation on Common Infectious Disease Symptoms and Gut Microbiota Modulation in Flu-Vaccinated Healthy Elderly Subjects. Biomed Res Int. 2022;2022:3860896. 10.1155/2022/3860896
- Mageswary MU, Ang XY, Lee BK, Chung YF, Azhar SNA, et al. Probiotic Bifidobacterium lactis Probio-M8 treated and prevented acute RTI, reduced antibiotic use and hospital stay in hospitalized young children: a randomized, double-blind, placebo-controlled study. Eur J Nutr. 2022;61:1679. 10.1007/s00394-021-02689-8
- Lenoir-Wijnkoop I, Merenstein D, Korchagina D, Broholm C, Sanders ME, et al. Probiotics Reduce Health Care Cost and Societal Impact of Flu-Like Respiratory Tract Infections in the USA: An Economic Modeling Study. Front Pharmacol. 2019;10:980. 10.3389/fphar.2019.00980
- Bo F, Yang WT, Shonyela SM, Jin YB, Huang KY, et al. Immune responses of mice inoculated with recombinant Lactobacillus plantarum NC8 expressing the fusion gene HA2 and 3M2e of the influenza virus and protection against different subtypes of influenza virus. Virus Res. 2019;263:64. 10.1016/j.virusres.2019.01.001
- Zhang H, Yeh C, Jin Z, Ding L, Liu BY, et al. Prospective study of probiotic supplementation results in immune stimulation and improvement of upper respiratory infection rate. Synth Syst Biotechnol. 2018;3:113. 10.1016/j.synbio.2018.03.001
- Belkacem N, Bourdet-Sicard R, Taha MK. Lactobacillus paracasei feeding improves the control of secondary experimental meningococcal infection in flu-infected mice. BMC Infect Dis. 2018;18:167. 10.1186/s12879-018-3086-9
- Belkacem N, Serafini N, Wheeler R, Derrien M, Boucinha L, et al. Lactobacillus paracasei feeding improves immune control of influenza infection in mice. PLoS One. 2017;12:e0184976. 10.1371/journal.pone.0184976
- Di Pierro F, Colombo M, Zanvit A, Rottoli AS. Positive clinical outcomes derived from using K12 to prevent streptococcal pharyngotonsillitis in children: a pilot investigation. Drug Healthc Patient Saf. 2016;8:77. PubMed
- Meng H, Lee Y, Ba Z, Peng J, Lin J, et al. Consumption of Bifidobacterium animalis subsp. lactis BB-12 impacts upper respiratory tract infection and the function of NK and T cells in healthy adults. Mol Nutr Food Res. 2016;60:1161. 10.1002/mnfr.201500665
- Lenoir-Wijnkoop I, Gerlier L, Bresson JL, Le Pen C, Berdeaux G. Public health and budget impact of probiotics on common respiratory tract infections: a modelling study. PLoS One. 2015;10:e0122765. 10.1371/journal.pone.0122765
- Langkamp-Henken B, Rowe CC, Ford AL, Christman MC, Nieves C, et al. Bifidobacterium bifidum R0071 results in a greater proportion of healthy days and a lower percentage of academically stressed students reporting a day of cold/flu: a randomised, double-blind, placebo-controlled study. Br J Nutr. 2015;113:426. 10.1017/S0007114514003997
- Kawase M, He F, Kubota A, Yoda K, Miyazawa K, et al. Heat-killed Lactobacillus gasseri TMC0356 protects mice against influenza virus infection by stimulating gut and respiratory immune responses. FEMS Immunol Med Microbiol. 2012;64:280. 10.1111/j.1574-695X.2011.00903.x
- Bieuvelet S, Seyrig C, Leclerc C. [A preliminary survey on the interest of eating probiotics, cypress and echinacea to prevent the apparition of winter infections]. Phytotherapie (Paris). 2011;9:120. 10.1007/s10298-011-0613-x
