Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 15 Researches
7.3
USERS' SCORE
Good
Based on 6 Reviews
8.6
Supplement Facts
Serving Size: 2 Veg Capsule
Amount Per Serving
%DV
Beta-1,3/1,6-D-Glucan Powder (from Saccharomyces cerevisiae)
500 mg
*
ImmunEnhancer [Arabinogalactan from Larch Tree (Larix occidentalis)]
400 mg
*
Top Medical Research Studies
8
Beta glucan shows anticancer potential
We examined how yeast-derived beta glucan could potentially assist in treating cervical cancer. Our study involved thorough testing to evaluate its effects on cancer cells, revealing that beta glucan generates reactive oxygen species, which can lead to cell apoptosis. We discovered that this substance effectively slows down the growth of cervical cancer cells at specific concentrations.
While these findings are promising, they indicate that further research is essential to fully understand its anticancer properties and potential as a safer alternative therapy alongside traditional treatments.
While these findings are promising, they indicate that further research is essential to fully understand its anticancer properties and potential as a safer alternative therapy alongside traditional treatments.
Read More
8
Beta-glucan enhances chemotherapy effects
We explored how beta-glucan from Ganoderma lucidum spores affects chemotherapy for triple-negative breast cancer, specifically looking at Gemcitabine treatment.
In our study with mice, we noticed that combining beta-glucan with chemotherapy reduced tumor sizes and helped counteract harmful changes in the tumor environment, like increased suppressor cells.
This treatment also helped boost immune responses by modifying how immune cells behave, offering a promising avenue to improve the efficacy of standard chemotherapy.
In our study with mice, we noticed that combining beta-glucan with chemotherapy reduced tumor sizes and helped counteract harmful changes in the tumor environment, like increased suppressor cells.
This treatment also helped boost immune responses by modifying how immune cells behave, offering a promising avenue to improve the efficacy of standard chemotherapy.
Read More
8
We explored the effectiveness of beta-glucan nanoparticles (NPs) in improving the oral delivery of gemcitabine, a cancer drug known for its poor bioavailability. Using a specific fabrication method, we created gemcitabine-loaded NPs that significantly enhanced drug absorption compared to the plain solution, achieving over five times greater bioavailability.
Our findings also revealed that these NPs could effectively reduce breast tumor growth in mice. This research suggests that beta-glucan NPs are a promising solution for enhancing chemotherapy options through oral administration.
Our findings also revealed that these NPs could effectively reduce breast tumor growth in mice. This research suggests that beta-glucan NPs are a promising solution for enhancing chemotherapy options through oral administration.
Read More
Most Useful Reviews
9
Stabilised sarcoma
87 people found this helpful
Helps me long-term in my battle against cancer. I wasn't aware of this product until my doctor recommended it after viewing my immune analysis, showing deficiencies in T-helpers and natural killers. Since I’m undergoing chemotherapy, I've needed support. I started taking this in 2018, and the effects are noticeable: stomatitis and skin fungi from chemotherapy have resolved. Most importantly, there is some stability in my underlying condition (sarcoma). I chose not to buy this last year, and within three months, I noticed a downturn. Hence, I’ve resolved to continue taking this for life, as it clearly has a positive effect!
Read More
9
Supports immune system
4 people found this helpful
This excellent product of Beta-glucans assists my daughter's immune system during and after chemotherapy! I find it a very effective product!
Read More
7.5
Shrunk tumour
2 people found this helpful
My husband underwent chemotherapy and radiotherapy for nasopharyngeal carcinoma at a late stage, and the tumour has since shrunk, which could be linked to this treatment.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 15 Researches
7.3
- All Researches
8
Beta glucans improve tumor targeting
We explored a novel oral delivery method for the chemotherapy drug paclitaxel (PTX) that incorporates beta glucans to improve absorption and effectiveness. During the study, we compared this new approach to traditional intravenous administration.
While intravenous PTX often leads to quick spikes and rapid elimination of the drug, our oral method offers a steadier release, potentially enhancing treatment effectiveness. The beta glucans act as smart transporters that help target tumors more precisely, ultimately improving the anti-cancer response without the drawbacks of conventional methods.
While intravenous PTX often leads to quick spikes and rapid elimination of the drug, our oral method offers a steadier release, potentially enhancing treatment effectiveness. The beta glucans act as smart transporters that help target tumors more precisely, ultimately improving the anti-cancer response without the drawbacks of conventional methods.
Read More
8
We investigated the effects of beta glucan when combined with IFNγ in treating metastatic ovarian cancer. This combination, known as BI, showed promising results by reducing tumor size and improving immune response.
Interestingly, beta glucan alone was able to clear excess fluid and target tumor cells effectively. The treatment not only helped enhance the action of chemotherapy in sensitive models, but it also assisted in extending survival in harder-to-treat cases.
Overall, this study points to beta glucan as a potential game changer for ovarian cancer therapies.
Interestingly, beta glucan alone was able to clear excess fluid and target tumor cells effectively. The treatment not only helped enhance the action of chemotherapy in sensitive models, but it also assisted in extending survival in harder-to-treat cases.
Overall, this study points to beta glucan as a potential game changer for ovarian cancer therapies.
Read More
8
Beta-glucan enhances chemotherapy effects
We explored how beta-glucan from Ganoderma lucidum spores affects chemotherapy for triple-negative breast cancer, specifically looking at Gemcitabine treatment.
In our study with mice, we noticed that combining beta-glucan with chemotherapy reduced tumor sizes and helped counteract harmful changes in the tumor environment, like increased suppressor cells.
This treatment also helped boost immune responses by modifying how immune cells behave, offering a promising avenue to improve the efficacy of standard chemotherapy.
In our study with mice, we noticed that combining beta-glucan with chemotherapy reduced tumor sizes and helped counteract harmful changes in the tumor environment, like increased suppressor cells.
This treatment also helped boost immune responses by modifying how immune cells behave, offering a promising avenue to improve the efficacy of standard chemotherapy.
Read More
8
We explored the effectiveness of beta-glucan nanoparticles (NPs) in improving the oral delivery of gemcitabine, a cancer drug known for its poor bioavailability. Using a specific fabrication method, we created gemcitabine-loaded NPs that significantly enhanced drug absorption compared to the plain solution, achieving over five times greater bioavailability.
Our findings also revealed that these NPs could effectively reduce breast tumor growth in mice. This research suggests that beta-glucan NPs are a promising solution for enhancing chemotherapy options through oral administration.
Our findings also revealed that these NPs could effectively reduce breast tumor growth in mice. This research suggests that beta-glucan NPs are a promising solution for enhancing chemotherapy options through oral administration.
Read More
8
β-Glucan shows potential against cancer
We looked into whether β-Glucan particles from Agaricus bisporus could aid in treating cervical cancer. Through our research, we observed that these particles showed promising antimicrobial and antioxidant effects while also targeting cancer cells.
The β-Glucan caused significant oxidative stress that led to apoptosis, effectively killing HeLa cancer cells. However, while the results are compelling, β-Glucan may not replace conventional treatments like chemotherapy at this point. Its role as a supportive therapy is noteworthy and deserves further exploration.
The β-Glucan caused significant oxidative stress that led to apoptosis, effectively killing HeLa cancer cells. However, while the results are compelling, β-Glucan may not replace conventional treatments like chemotherapy at this point. Its role as a supportive therapy is noteworthy and deserves further exploration.
Read More
User Reviews
USERS' SCORE
Good
Based on 6 Reviews
8.6
- All Reviews
- Positive Reviews
- Negative Reviews
9
Stabilised sarcoma
87 people found this helpful
Helps me long-term in my battle against cancer. I wasn't aware of this product until my doctor recommended it after viewing my immune analysis, showing deficiencies in T-helpers and natural killers. Since I’m undergoing chemotherapy, I've needed support. I started taking this in 2018, and the effects are noticeable: stomatitis and skin fungi from chemotherapy have resolved. Most importantly, there is some stability in my underlying condition (sarcoma). I chose not to buy this last year, and within three months, I noticed a downturn. Hence, I’ve resolved to continue taking this for life, as it clearly has a positive effect!
Read More
9
Supports immune system
4 people found this helpful
This excellent product of Beta-glucans assists my daughter's immune system during and after chemotherapy! I find it a very effective product!
Read More
7.5
Shrunk tumour
2 people found this helpful
My husband underwent chemotherapy and radiotherapy for nasopharyngeal carcinoma at a late stage, and the tumour has since shrunk, which could be linked to this treatment.
Read More
7.5
Less side effects
1 people found this helpful
I have repurchased this, taking it alongside AHCC fucoidan during chemotherapy. The side effects were less than anticipated—how wonderful!
Read More
7.5
Mitigated damage
Beta-glucans have been shown to assist with chemotherapy and radiation treatments, mitigating the damage caused by these therapies. It's a superb product!
Read More
Frequently Asked Questions
9
Stabilised sarcoma
87 people found this helpful
Helps me long-term in my battle against cancer. I wasn't aware of this product until my doctor recommended it after viewing my immune analysis, showing deficiencies in T-helpers and natural killers. Since I’m undergoing chemotherapy, I've needed support. I started taking this in 2018, and the effects are noticeable: stomatitis and skin fungi from chemotherapy have resolved. Most importantly, there is some stability in my underlying condition (sarcoma). I chose not to buy this last year, and within three months, I noticed a downturn. Hence, I’ve resolved to continue taking this for life, as it clearly has a positive effect!
9
Supports immune system
4 people found this helpful
This excellent product of Beta-glucans assists my daughter's immune system during and after chemotherapy! I find it a very effective product!
7.5
Less side effects
1 people found this helpful
I have repurchased this, taking it alongside AHCC fucoidan during chemotherapy. The side effects were less than anticipated—how wonderful!
7.5
Mitigated damage
Beta-glucans have been shown to assist with chemotherapy and radiation treatments, mitigating the damage caused by these therapies. It's a superb product!
References
- Nguyen N, Hoang TM, Huang TY, Nguyen LD, Chang HH, et al. Macrophage-hitchhiked, effervescence-induced nanoemulsions for enhanced oral chemotherapy and immunotherapy: Impact on absorption route. Biomaterials. 2025;316:123019. doi:10.1016/j.biomaterials.2024.123019
- Murphy B, Miyamoto T, Manning BS, Mirji G, Ugolini A, et al. Myeloid activation clears ascites and reveals IL27-dependent regression of metastatic ovarian cancer. J Exp Med. 2024;221. doi:10.1084/jem.20231967
- Geng Q, Lu Y, Li D, Qin L, Qi C, et al. β-glucan combined with Envafolimab and Endostar as immune rechallenge for metastatic non-small cell lung cancer. BMC Immunol. 2024;25:60. doi:10.1186/s12865-024-00651-x
- Chu Y, He X, Xue Y, Jiang H, Zhu C, et al. An exploratory clinical study of β-glucan combined with camrelizumab and SOX chemotherapy as first-line treatment for advanced gastric adenocarcinoma. Front Immunol. 2024;15:1448485. doi:10.3389/fimmu.2024.1448485
- Murphy B, Miyamoto T, Manning BS, Mirji G, Ugolini A, et al. Intraperitoneal activation of myeloid cells clears ascites and reveals IL27-dependent regression of metastatic ovarian cancer. bioRxiv. 2024. doi:10.1101/2024.06.25.600597
- Ostadrahimi A, Ahmadikhatir S, Amirazad H, EivaziZiaei J, AsghariJafarabadi M, et al. Effect of combination of Beta Glucan and Lactobacillus rhamnosus HerizI on white blood cell counts and serum levels of IL-4 and IL-12 in women with breast cancer undergoing chemotherapy: A randomized double-blind placebo-controlled clinical trial. Clin Nutr ESPEN. 2024;61:281. doi:10.1016/j.clnesp.2024.03.035
- Bu Y, Liu Q, Shang Y, Zhao Z, Sun H, et al. Ganoderma lucidum spores-derived particulate β-glucan treatment improves antitumor response by regulating myeloid-derived suppressor cells in triple-negative breast cancer. Int J Biol Macromol. 2024;270:131949. doi:10.1016/j.ijbiomac.2024.131949
- Chen G, Liu Y, Svirskis D, Li H, Ying M, et al. Cryo-Milled β-Glucan Nanoparticles for Oral Drug Delivery. Pharmaceutics. 2024;16. doi:10.3390/pharmaceutics16040546
- Zhou G, Liu H, Yuan Y, Wang Q, Wang L, et al. Lentinan progress in inflammatory diseases and tumor diseases. Eur J Med Res. 2024;29:8. doi:10.1186/s40001-023-01585-7
- Zeyaullah M, Alam MS, Al-Najjar MAA. Investigation on Antimicrobial, Antioxidant, and Anti-cancerous activity of Agaricus bisporus derived β-Glucan particles against cervical cancer cell line. Cell Mol Biol (Noisy-le-grand). 2022;68:150. doi:10.14715/cmb/2022.68.9.24
- Upadhyay TK, Trivedi R, Khan F, Al-Keridis LA, Pandey P, et al. elucidation of antioxidant, antiproliferative, and apoptotic potential of yeast-derived β-1,3-glucan particles against cervical cancer cells. Front Oncol. 2022;12:942075. doi:10.3389/fonc.2022.942075
- Song Y, Shin H, Sianipar HGJ, Park JY, Lee M, et al. Oral administration of Euglena gracilis paramylon ameliorates chemotherapy-induced leukocytopenia and gut dysbiosis in mice. Int J Biol Macromol. 2022;211:47. doi:10.1016/j.ijbiomac.2022.04.168
- Yehia RS. Evaluation of the biological activities of β-glucan isolated from Lentinula edodes. Lett Appl Microbiol. 2022;75:317. doi:10.1111/lam.13727
- Fujiike AY, Lee CYAL, Rodrigues FST, Oliveira LCB, Barbosa-Dekker AM, et al. Anticancer effects of carboxymethylated (1→3)(1→6)-β-D-glucan (botryosphaeran) on multicellular tumor spheroids of MCF-7 cells as a model of breast cancer. J Toxicol Environ Health A. 2022;85:521. doi:10.1080/15287394.2022.2048153
- Rutckeviski R, Corso CR, Román-Ochoa Y, Cipriani TR, Centa A, et al. Agaricus bisporus β-(1 → 6)-d-glucan induces M1 phenotype on macrophages and increases sensitivity to doxorubicin of triple negative breast cancer cells. Carbohydr Polym. 2022;278:118917. doi:10.1016/j.carbpol.2021.118917
