Last update
3/30/2026
Reviewed By
Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 16 Researches
7.4
USERS' SCORE
Good
Based on 8 Reviews
8.7
Supplement Facts
Serving Size: 1 Capsule
Amount Per Serving
%DV
Turmeric ExtractCurcuma longa (Rhizome)(95% [475 mg] Total Curcuminoids)
500 mg
†
Top Medical Research Studies
9
Turmeric curcumin reduces mucositis symptoms
We examined how different forms of turmeric curcumin could help ease oral mucositis symptoms in patients undergoing chemotherapy and radiotherapy. This systematic review and meta-analysis included randomized clinical trials aligned with PRISMA guidelines, focusing on studies that measured severity and pain associated with oral mucositis against a placebo.
Our findings suggest that curcumin, in various formulations, does show effectiveness in reducing both the severity of symptoms and associated pain. Additionally, a curcumin mouthwash was found to lower the incidence of oral mucositis.
Our findings suggest that curcumin, in various formulations, does show effectiveness in reducing both the severity of symptoms and associated pain. Additionally, a curcumin mouthwash was found to lower the incidence of oral mucositis.
Read More
9
Tetrahydrocurcumin delivery enhancement study
We explored the potential of tetrahydrocurcumin as a cancer-fighting agent by improving its solubility through an innovative drug delivery system using β-cyclodextrin. This approach allowed us to achieve a remarkable increase in aqueous dispersion, which led to stronger anticancer effects in both lab tests and studies involving mice.
The results showed significant tumor regression and reduced systemic toxicity. Moreover, markers for tumor presence decreased notably with treatment, highlighting the value of this formulation in enhancing the effectiveness of cancer chemotherapy, particularly for colorectal cancer.
The results showed significant tumor regression and reduced systemic toxicity. Moreover, markers for tumor presence decreased notably with treatment, highlighting the value of this formulation in enhancing the effectiveness of cancer chemotherapy, particularly for colorectal cancer.
Read More
9
Curcumin shows promise against PIPN
We tested the effects of a dietary curcumin formulation on preventing nerve damage caused by the chemotherapy drug paclitaxel in mice. Our research showed that while a standard curcumin diet partially helped reduce nerve sensitivity, a specialized formulation called Meriva provided complete protection against nerve damage and inflammation.
The study revealed that Meriva not only prevented hypersensitivity from cold stimuli but also safeguarded nerve function more effectively than the standard diet. Our findings suggest that curcumin, particularly through its interaction with specific receptors, holds substantial promise in mitigating chemotherapy-induced nerve issues.
The study revealed that Meriva not only prevented hypersensitivity from cold stimuli but also safeguarded nerve function more effectively than the standard diet. Our findings suggest that curcumin, particularly through its interaction with specific receptors, holds substantial promise in mitigating chemotherapy-induced nerve issues.
Read More
Most Useful Reviews
9
Joint pain relief
641 people found this helpful
Good functions. I’m purchasing this product for the second time. I began taking this supplement after chemotherapy, as my finger joints started to swell. The rheumatologist prescribed a treatment course that I couldn’t follow due to liver constraints. A week after starting curcumin, I noticed my joints no longer swelled or ached. Since then, I’ve taken it consistently for three years. I hope my feedback is useful.
Read More
9
Effective for swelling
5 people found this helpful
Good features. I’m buying this product for the second time. I started taking this supplement after chemotherapy, and my finger joints began to swell. The rheumatologist prescribed a treatment that I couldn’t take due to liver issues. A week after starting curcumin, I realised my joints stopped swelling and hurting. I've now taken it continuously for three years. I hope my review helps.
Read More
9
Joint pain relief
1 people found this helpful
Excellent! Good features. I purchased this product again. After beginning this supplement post-chemotherapy, my finger joints began swelling. The rheumatologist prescribed a treatment which I couldn't take due to liver strain. A week after starting curcumin, I found my joints no longer swelled or hurt. I’ve taken it continuously for three years since then.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 16 Researches
7.4
- All Researches
9
Turmeric curcumin reduces mucositis symptoms
We examined how different forms of turmeric curcumin could help ease oral mucositis symptoms in patients undergoing chemotherapy and radiotherapy. This systematic review and meta-analysis included randomized clinical trials aligned with PRISMA guidelines, focusing on studies that measured severity and pain associated with oral mucositis against a placebo.
Our findings suggest that curcumin, in various formulations, does show effectiveness in reducing both the severity of symptoms and associated pain. Additionally, a curcumin mouthwash was found to lower the incidence of oral mucositis.
Our findings suggest that curcumin, in various formulations, does show effectiveness in reducing both the severity of symptoms and associated pain. Additionally, a curcumin mouthwash was found to lower the incidence of oral mucositis.
Read More
9
Tetrahydrocurcumin delivery enhancement study
We explored the potential of tetrahydrocurcumin as a cancer-fighting agent by improving its solubility through an innovative drug delivery system using β-cyclodextrin. This approach allowed us to achieve a remarkable increase in aqueous dispersion, which led to stronger anticancer effects in both lab tests and studies involving mice.
The results showed significant tumor regression and reduced systemic toxicity. Moreover, markers for tumor presence decreased notably with treatment, highlighting the value of this formulation in enhancing the effectiveness of cancer chemotherapy, particularly for colorectal cancer.
The results showed significant tumor regression and reduced systemic toxicity. Moreover, markers for tumor presence decreased notably with treatment, highlighting the value of this formulation in enhancing the effectiveness of cancer chemotherapy, particularly for colorectal cancer.
Read More
9
Curcumin shows promise against PIPN
We tested the effects of a dietary curcumin formulation on preventing nerve damage caused by the chemotherapy drug paclitaxel in mice. Our research showed that while a standard curcumin diet partially helped reduce nerve sensitivity, a specialized formulation called Meriva provided complete protection against nerve damage and inflammation.
The study revealed that Meriva not only prevented hypersensitivity from cold stimuli but also safeguarded nerve function more effectively than the standard diet. Our findings suggest that curcumin, particularly through its interaction with specific receptors, holds substantial promise in mitigating chemotherapy-induced nerve issues.
The study revealed that Meriva not only prevented hypersensitivity from cold stimuli but also safeguarded nerve function more effectively than the standard diet. Our findings suggest that curcumin, particularly through its interaction with specific receptors, holds substantial promise in mitigating chemotherapy-induced nerve issues.
Read More
8
We evaluated the effects of turmeric’s curcumin and its derivatives on triple-negative breast cancer (TNBC). By using a variety of synthetic compounds, we saw that certain derivatives, particularly TL3, showed strong potential against both TNBC cells and cancer stem-like cells.
Notably, when combined with chemotherapeutic agents such as doxorubicin and cisplatin, TL3 amplified their effectiveness, indicating a promising strategy for enhancing cancer treatment. This study highlights the potential for curcumin in addressing the challenges posed by aggressive tumors.
Notably, when combined with chemotherapeutic agents such as doxorubicin and cisplatin, TL3 amplified their effectiveness, indicating a promising strategy for enhancing cancer treatment. This study highlights the potential for curcumin in addressing the challenges posed by aggressive tumors.
Read More
8
We explored the effects of a novel surfactant-formulated curcumin on chemotherapy-resistant colorectal cancer. This formulation improved curcumin's water solubility, allowing it to show promising anti-cancer activities in resistant cancer cell lines.
We observed that this specialized curcumin induced cell death and disrupted cancer cell growth cycles effectively. It also appeared to impact immune responses related to gut cancer.
While the findings are encouraging, further research is needed to fully understand curcumin's potential in clinical settings.
We observed that this specialized curcumin induced cell death and disrupted cancer cell growth cycles effectively. It also appeared to impact immune responses related to gut cancer.
While the findings are encouraging, further research is needed to fully understand curcumin's potential in clinical settings.
Read More
User Reviews
USERS' SCORE
Good
Based on 8 Reviews
8.7
- All Reviews
- Positive Reviews
- Negative Reviews
9
Joint pain relief
641 people found this helpful
Good functions. I’m purchasing this product for the second time. I began taking this supplement after chemotherapy, as my finger joints started to swell. The rheumatologist prescribed a treatment course that I couldn’t follow due to liver constraints. A week after starting curcumin, I noticed my joints no longer swelled or ached. Since then, I’ve taken it consistently for three years. I hope my feedback is useful.
Read More
9
Effective for swelling
5 people found this helpful
Good features. I’m buying this product for the second time. I started taking this supplement after chemotherapy, and my finger joints began to swell. The rheumatologist prescribed a treatment that I couldn’t take due to liver issues. A week after starting curcumin, I realised my joints stopped swelling and hurting. I've now taken it continuously for three years. I hope my review helps.
Read More
9
Joint pain relief
1 people found this helpful
Excellent! Good features. I purchased this product again. After beginning this supplement post-chemotherapy, my finger joints began swelling. The rheumatologist prescribed a treatment which I couldn't take due to liver strain. A week after starting curcumin, I found my joints no longer swelled or hurt. I’ve taken it continuously for three years since then.
Read More
9
Improved appetite
I lost my appetite after chemotherapy, making it hard to eat. A week into taking Curcumin, I felt a desire to eat again and my health improved.
Read More
7.5
Doctor's recommendation
1 people found this helpful
Excellent product; my doctor recommended it to me after chemotherapy.
Read More
Frequently Asked Questions
9
Joint pain relief
641 people found this helpful
Good functions. I’m purchasing this product for the second time. I began taking this supplement after chemotherapy, as my finger joints started to swell. The rheumatologist prescribed a treatment course that I couldn’t follow due to liver constraints. A week after starting curcumin, I noticed my joints no longer swelled or ached. Since then, I’ve taken it consistently for three years. I hope my feedback is useful.
9
Joint pain relief
1 people found this helpful
Excellent! Good features. I purchased this product again. After beginning this supplement post-chemotherapy, my finger joints began swelling. The rheumatologist prescribed a treatment which I couldn't take due to liver strain. A week after starting curcumin, I found my joints no longer swelled or hurt. I’ve taken it continuously for three years since then.
9
Improved appetite
I lost my appetite after chemotherapy, making it hard to eat. A week into taking Curcumin, I felt a desire to eat again and my health improved.
7.5
Supports chemotherapy
At Oncology, I give my son chemotherapy throughout treatment. Of course, I don’t give it on those days, but between sessions, we’ve been taking it for a year. It’s a wonderful product that helps counteract the impacts of chemotherapy and supports joint health.
9
Effective for swelling
5 people found this helpful
Good features. I’m buying this product for the second time. I started taking this supplement after chemotherapy, and my finger joints began to swell. The rheumatologist prescribed a treatment that I couldn’t take due to liver issues. A week after starting curcumin, I realised my joints stopped swelling and hurting. I've now taken it continuously for three years. I hope my review helps.
References
- Amatto PPG, Chaves L, França SC, Carvalho JCT, Carmona F, et al. Efficacy of different pharmaceutical forms of or curcumin in reducing oral mucositis severity and incidence in cancer patients: a systematic review and meta-analysis. Front Pharmacol. 2025;16:1560729. 10.3389/fphar.2025.1560729
- Poma P, Massaro M, Rigogliuso S, Condorelli L, Sánchez-Espejo R, et al. Curcumin and doxorubicin encapsulated in biocompatible clay-based nanomaterial: A strategy to overcome multidrug resistance. Arch Pharm (Weinheim). 2025;358:e2400702. 10.1002/ardp.202400702
- Dipalma G, Inchingolo AM, Latini G, Ferrante L, Nardelli P, et al. The Effectiveness of Curcumin in Treating Oral Mucositis Related to Radiation and Chemotherapy: A Systematic Review. Antioxidants (Basel). 2024;13. 10.3390/antiox13101160
- Low ZX, Teo MYM, Juliana Nordin F, Palanirajan VK, Morak-Młodawska B, et al. Enhancing the solubility and potency of tetrahydrocurcumin as an anti-cancer agent using a β-cyclodextrin inclusion complex approach. PLoS One. 2024;19:e0305171. 10.1371/journal.pone.0305171
- Ros M, Riesco-Llach G, Polonio-Alcalá E, Morla-Barcelo PM, Ruiz-Martínez S, et al. Inhibition of Cancer Stem-like Cells by Curcumin and Other Polyphenol Derivatives in MDA-MB-231 TNBC Cells. Int J Mol Sci. 2024;25. 10.3390/ijms25137446
- Shnaikat SG, Shakya AK, Bardaweel SK. Formulation, development and evaluation of hyaluronic acid-conjugated liposomal nanoparticles loaded with regorafenib and curcumin and their in vitro evaluation on colorectal cancer cell lines. Saudi Pharm J. 2024;32:102099. 10.1016/j.jsps.2024.102099
- Wan C, Ma Q, Anderson S, Zhang QH, Zhang CF, et al. Effects of Curcuminoids and Surfactant-Formulated Curcumin on Chemo-Resistant Colorectal Cancer. Am J Chin Med. 2023;51:1577. 10.1142/S0192415X23500714
- de Waure C, Bertola C, Baccarini G, Chiavarini M, Mancuso C. Exploring the Contribution of Curcumin to Cancer Therapy: A Systematic Review of Randomized Controlled Trials. Pharmaceutics. 2023;15. 10.3390/pharmaceutics15041275
- Liu X, Qi M, Li X, Wang J, Wang M. Curcumin: a natural organic component that plays a multi-faceted role in ovarian cancer. J Ovarian Res. 2023;16:47. 10.1186/s13048-023-01120-6
- Brockmueller A, Samuel SM, Mazurakova A, Büsselberg D, Kubatka P, et al. Curcumin, calebin A and chemosensitization: How are they linked to colorectal cancer?. Life Sci. 2023;318:121504. 10.1016/j.lfs.2023.121504
- Yang J, He C, Liu N. Proteomic analysis of the chemosensitizing effect of curcumin on CRC cells treated with 5-FU. Front Med (Lausanne). 2022;9:1032256. 10.3389/fmed.2022.1032256
- Gor R, Ramachandran I, Ramalingam S. Targeting the Cancer Stem Cells in Endocrine Cancers with Phytochemicals. Curr Top Med Chem. 2022;22:2589. 10.2174/1567205020666221114112814
- Caillaud M, Thompson D, Toma W, White A, Mann J, et al. Formulated Curcumin Prevents Paclitaxel-Induced Peripheral Neuropathy through Reduction in Neuroinflammation by Modulation of α7 Nicotinic Acetylcholine Receptors. Pharmaceutics. 2022;14. 10.3390/pharmaceutics14061296
- Armandeh M, Bameri B, Samadi M, Heidari S, Foroumadi R, et al. A Systematic Review of Nonclinical Studies on the Effect of Curcumin in Chemotherapy- induced Cardiotoxicity. Curr Pharm Des. 2022;28:1843. 10.2174/1381612828666220513125312
- Barinda AJ, Arozal W, Sandhiutami NMD, Louisa M, Arfian N, et al. Curcumin Prevents Epithelial-to Mesenchymal Transition-Mediated Ovarian Cancer Progression through NRF2/ETBR/ET-1 Axis and Preserves Mitochondria Biogenesis in Kidney after Cisplatin Administration. Adv Pharm Bull. 2022;12:128. 10.34172/apb.2022.014
- Karaboga Arslan AK, Uzunhisarcıklı E, Yerer MB, Bishayee A. The golden spice curcumin in cancer: A perspective on finalized clinical trials during the last 10 years. J Cancer Res Ther. 2022;18:19. 10.4103/jcrt.JCRT_1017_20
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