Beet
9
This study explored how beet leaf extract affects anemia in a laboratory model using albino rats. We induced hemolytic anemia and treated the rats with different doses of beet extract along with standard treatments. The results were promising, showing that beet leaf extract significantly boosted levels of red blood cells and hemoglobin over time. Additionally, it demonstrated antioxidant properties that may contribute to its effectiveness. Overall, these findings suggest beet leaf extract could be a natural option for treating anemia.
9.5
Improved hair growth
Most Useful Review
The quality is excellent, and I noticed a significant improvement in my anaemia after I started taking two pills daily on an empty stomach. Within two months, my hair became thicker, and my skin improved remarkably. I highly recommend these pills as they effectively raise iron levels and have a pleasant sweet taste reminiscent of beets.
Magnesium
8
We explored the case of a 10-year-old boy diagnosed with congenital sideroblastic anemia (CSA). This condition can lead to severe anemia due to the body’s ineffective production of red blood cells. As part of the investigation, we performed various blood tests and conducted gene mutation analysis to identify any underlying causes.
We identified a novel genetic variant (c.1102C > T:p. Arg368Trp) that seemed to play a significant role in this boy's anemia. Notably, the treatment regimen included vitamin B6, known to help in certain cases of sideroblastic anemia, along with another medication called deferasirox. After six months of treatment, the patient saw significant improvement; his hemoglobin levels rose significantly, and iron overload was managed effectively.
While our findings suggest that vitamin B6 can be beneficial for some patients with CSA, it was combined with deferasirox in this instance. Consequently, isolating the exact impact of vitamin B6 on the anemia proves challenging. Nevertheless, this case highlights the importance of mutational analysis and tailored treatments in managing inherited blood disorders.
We identified a novel genetic variant (c.1102C > T:p. Arg368Trp) that seemed to play a significant role in this boy's anemia. Notably, the treatment regimen included vitamin B6, known to help in certain cases of sideroblastic anemia, along with another medication called deferasirox. After six months of treatment, the patient saw significant improvement; his hemoglobin levels rose significantly, and iron overload was managed effectively.
While our findings suggest that vitamin B6 can be beneficial for some patients with CSA, it was combined with deferasirox in this instance. Consequently, isolating the exact impact of vitamin B6 on the anemia proves challenging. Nevertheless, this case highlights the importance of mutational analysis and tailored treatments in managing inherited blood disorders.
9.5
Life-changing relief
Most Useful Review
I suffer from VSD and a lack of magnesium B6, which caused issues like dizziness, heart palpitations, and anemia. Since taking magnesium B6, my life has greatly improved; all symptoms have nearly vanished! I now take 3-4 tablets an hour before bed and sleep wonderfully. This brand is among the best, and I always opt for quality!
Calcium Magnesium
9
We investigated how persistent hypercalcemia—elevated calcium levels—affects hemoglobin levels in kidney transplant recipients (KTRs). Through a retrospective study including 385 patients, we analyzed the trajectories of hemoglobin in those with and without hypercalcemia.
Our findings revealed a surprising link: KTRs with persistent hypercalcemia exhibited higher hemoglobin levels over time—an increase of about 0.76 g/dL per year. This was especially pronounced in men, who showed an increase of 0.80 g/dL per year, compared to a more modest rise of 0.36 g/dL per year in women.
Additionally, our data indicated that these patients had a greater risk of developing post-transplant erythrocytosis, a condition characterized by an elevated red blood cell count. This relationship invites further consideration about the role of calcium levels in blood health, suggesting that rather than causing anemia as might be expected, hypercalcemia may drive erythrocytosis in this unique patient population.
Overall, this study emphasizes the complexity of calcium’s role in post-transplant health and highlights the importance of monitoring hemoglobin levels in KTRs, especially those with persistent hypercalcemia.
Our findings revealed a surprising link: KTRs with persistent hypercalcemia exhibited higher hemoglobin levels over time—an increase of about 0.76 g/dL per year. This was especially pronounced in men, who showed an increase of 0.80 g/dL per year, compared to a more modest rise of 0.36 g/dL per year in women.
Additionally, our data indicated that these patients had a greater risk of developing post-transplant erythrocytosis, a condition characterized by an elevated red blood cell count. This relationship invites further consideration about the role of calcium levels in blood health, suggesting that rather than causing anemia as might be expected, hypercalcemia may drive erythrocytosis in this unique patient population.
Overall, this study emphasizes the complexity of calcium’s role in post-transplant health and highlights the importance of monitoring hemoglobin levels in KTRs, especially those with persistent hypercalcemia.
9
Condition improved
Most Useful Review
I took it when symptoms of anemia appeared and completed the course; my condition improved. I love this brand and would recommend it.
B12
8
This case explores the journey of a 40-year-old woman who suffered from various nonspecific symptoms, mistakenly attributed to other health issues, for ten years. Her vitamin B12 levels were critically low, ultimately diagnosed as pernicious anemia.
After starting parenteral B12 treatment, we observed significant neurological improvements, underscoring how vital it is to recognize vitamin B12 deficiency as a potential cause of anemia, even when classic symptoms aren't present. This case reminds us to maintain a broad perspective for accurate diagnosis.
After starting parenteral B12 treatment, we observed significant neurological improvements, underscoring how vital it is to recognize vitamin B12 deficiency as a potential cause of anemia, even when classic symptoms aren't present. This case reminds us to maintain a broad perspective for accurate diagnosis.
9.5
Convenient anaemia solution
Most Useful Review
I have a positive impression of these vitamins. The vitamin B12 spray format is convenient for children, avoiding injections or pills. As someone with low hemoglobin and a restricted diet, I find these vitamins helpful. No side effects, and after a month, my hair stopped falling out, and chronic fatigue disappeared.
B6 Pyridoxine
8
We explored the case of a 10-year-old boy diagnosed with congenital sideroblastic anemia (CSA). This condition can lead to severe anemia due to the body’s ineffective production of red blood cells. As part of the investigation, we performed various blood tests and conducted gene mutation analysis to identify any underlying causes.
We identified a novel genetic variant (c.1102C > T:p. Arg368Trp) that seemed to play a significant role in this boy's anemia. Notably, the treatment regimen included vitamin B6, known to help in certain cases of sideroblastic anemia, along with another medication called deferasirox. After six months of treatment, the patient saw significant improvement; his hemoglobin levels rose significantly, and iron overload was managed effectively.
While our findings suggest that vitamin B6 can be beneficial for some patients with CSA, it was combined with deferasirox in this instance. Consequently, isolating the exact impact of vitamin B6 on the anemia proves challenging. Nevertheless, this case highlights the importance of mutational analysis and tailored treatments in managing inherited blood disorders.
We identified a novel genetic variant (c.1102C > T:p. Arg368Trp) that seemed to play a significant role in this boy's anemia. Notably, the treatment regimen included vitamin B6, known to help in certain cases of sideroblastic anemia, along with another medication called deferasirox. After six months of treatment, the patient saw significant improvement; his hemoglobin levels rose significantly, and iron overload was managed effectively.
While our findings suggest that vitamin B6 can be beneficial for some patients with CSA, it was combined with deferasirox in this instance. Consequently, isolating the exact impact of vitamin B6 on the anemia proves challenging. Nevertheless, this case highlights the importance of mutational analysis and tailored treatments in managing inherited blood disorders.
8.8
Increases energy levels
Most Useful Review
After taking vitamin B6, I noticed a significant boost in energy and less weakness. My gums also improved, which I attributed to previously unnoticed anaemia from a B vitamin deficiency. I had struggled with these issues for a long time.
Vitamin B Complex
8
We explored a compelling case of pernicious anemia in a 51-year-old Ugandan man presenting with lower limb weakness. Initially treated for vitamin B12 deficiency years earlier, he experienced similar symptoms once again.
Through careful testing, he was diagnosed with pernicious anemia, confirming that a lack of vitamin B12 affects many aspects of health. The patient showed improvement after receiving parenteral methylcobalamin therapy, indicating that vitamin B complex can be beneficial in treating anemia caused by deficiencies.
This case underlines the need for awareness and early diagnosis of vitamin B12 deficiency, especially in resource-limited settings.
Through careful testing, he was diagnosed with pernicious anemia, confirming that a lack of vitamin B12 affects many aspects of health. The patient showed improvement after receiving parenteral methylcobalamin therapy, indicating that vitamin B complex can be beneficial in treating anemia caused by deficiencies.
This case underlines the need for awareness and early diagnosis of vitamin B12 deficiency, especially in resource-limited settings.
8.8
Supports energy production
Most Useful Review
Excellent composition! I take these vitamins daily, finding them delicious and effective against anaemia. They support energy and biochemical processes. I highly recommend them, especially since they're hard to find elsewhere.
Spirulina
9
Spirulina shows promise in anemia
We explored the effects of a naturopathic approach on an infant diagnosed with hereditary spherocytosis, a form of inherited hemolytic anemia. After receiving multiple blood transfusions, the patient began treatment with spirulina and chlorophyll. Remarkably, he was able to maintain normal hemoglobin levels and has not required additional blood transfusions for over seven months following the start of this therapy. This case suggests that natural interventions could support hemoglobin levels in patients with this condition.
9.5
Positive changes noted
Most Useful Review
I started giving my 8-month-old daughter spirulina for her anaemia upon my nutritionist's advice. Within two weeks, I've noticed positive changes in her energy and activity levels, although I dislike the taste.
Lactoferrin
9
We explored an important question regarding anemia management in children with chronic kidney disease (CKD). In a randomized clinical trial, we compared the effectiveness of oral lactoferrin and intravenous iron dextran in treating anemia related to CKD in pediatrics.
The study involved 60 children who were divided into two groups: one received 100 mg of oral lactoferrin daily for three months, while the other group was treated with IV iron dextran three times a week. After the treatment period, we observed significant changes in several blood parameters among those taking oral lactoferrin, specifically in hemoglobin, red blood cells, and various other indicators related to anemia.
However, while both treatments proved effective, we found no significant differences between the two groups overall in improving anemia symptoms after three months. Ultimately, while oral lactoferrin showed promising results, it did not outperform IV iron dextran to a degree that would change treatment choices.
The study involved 60 children who were divided into two groups: one received 100 mg of oral lactoferrin daily for three months, while the other group was treated with IV iron dextran three times a week. After the treatment period, we observed significant changes in several blood parameters among those taking oral lactoferrin, specifically in hemoglobin, red blood cells, and various other indicators related to anemia.
However, while both treatments proved effective, we found no significant differences between the two groups overall in improving anemia symptoms after three months. Ultimately, while oral lactoferrin showed promising results, it did not outperform IV iron dextran to a degree that would change treatment choices.
9.5
Ferritin has risen
Most Useful Review
I am truly grateful that I discovered Lactoferrin! I have chronic anaemia and struggled to increase my ferritin levels. After ceasing iron supplements, my ferritin dropped to 3. Thankfully, Lactoferrin raised it to 56! My health has greatly improved; my depression has lifted, my sleep quality has enhanced, and I've gained warmth in my limbs. This supplement has remarkable properties against various viruses and aids in cell oxygenation, boosting stamina and recovery from illness.
Vitamin Bs
7
Factors influencing supplement adherence
We conducted an unmatched case-control study in Bule Hora district, Southern Ethiopia, aiming to understand what factors affect pregnant women’s compliance with iron and folic acid supplementation. This is crucial because these supplements are recommended to help prevent anemia during pregnancy, a common issue in many areas including Ethiopia.
Our research included 115 cases of women who adhered to supplementation and 230 controls who did not. We focused on various influencers such as health care interactions, knowledge about anemia, and support from partners. Interestingly, we found that the likelihood of compliance increased with factors like being a first-time mother, attending antenatal care at least four times, receiving support from husbands, and having solid knowledge about anemia.
From our findings, it’s clear that enhancing support from partners and improving the overall frequency of health care contacts can significantly boost compliance with iron and folic acid supplementation. Sharing information about anemia with expectant mothers also plays a vital role in increasing adherence to these important health recommendations.
Our research included 115 cases of women who adhered to supplementation and 230 controls who did not. We focused on various influencers such as health care interactions, knowledge about anemia, and support from partners. Interestingly, we found that the likelihood of compliance increased with factors like being a first-time mother, attending antenatal care at least four times, receiving support from husbands, and having solid knowledge about anemia.
From our findings, it’s clear that enhancing support from partners and improving the overall frequency of health care contacts can significantly boost compliance with iron and folic acid supplementation. Sharing information about anemia with expectant mothers also plays a vital role in increasing adherence to these important health recommendations.
9.5
Significant improvement
Most Useful Review
Helped me with anemia. Initially, my level was 104, but after a month it rose to 131. I am very happy and continue to drink it.
Vitamins
9
We examined the connection between vitamin A deficiency (VAD) and anemia, particularly how a lack of vitamin A can impact iron metabolism in our bodies. Through reviewing existing research, we discovered that VAD doesn't just lead to general anemia but may cause a specific type known as vitamin A deficiency anemia (VADA).
Our findings reveal that vitamin A plays an essential role in the production of red blood cells. When we lack vitamin A, our bodies struggle to utilize iron effectively. Instead of being available for red blood cell production, iron accumulates in our liver and spleen, leading to reduced levels of circulating iron.
We also saw that inflammation and systemic infections could further exacerbate this issue by triggering the liver to produce more hepcidin, a protein that regulates iron levels. The excess hepcidin can create a situation where there isn’t enough iron for the production of hemoglobin, ultimately causing anemia.
Interestingly, our review highlighted that VADA happens not because of a lack of iron, but due to how iron is managed within the body. By understanding these mechanisms, we can work towards creating better strategies to tackle anemia on a global scale.
Our findings reveal that vitamin A plays an essential role in the production of red blood cells. When we lack vitamin A, our bodies struggle to utilize iron effectively. Instead of being available for red blood cell production, iron accumulates in our liver and spleen, leading to reduced levels of circulating iron.
We also saw that inflammation and systemic infections could further exacerbate this issue by triggering the liver to produce more hepcidin, a protein that regulates iron levels. The excess hepcidin can create a situation where there isn’t enough iron for the production of hemoglobin, ultimately causing anemia.
Interestingly, our review highlighted that VADA happens not because of a lack of iron, but due to how iron is managed within the body. By understanding these mechanisms, we can work towards creating better strategies to tackle anemia on a global scale.
8.8
Improved hemoglobin levels
Most Useful Review
The syrup is palatable, does not cause constipation, and increases haemoglobin within a month. I noticed latent anaemia in my child, indicated by blood tests showing low erythrocyte levels and high platelets. I often see this in children whose mothers report poor sleep and fatigue. Monitoring every six months is essential, with an individual dosage usually between 10-15 mg.
Iron
8
We aimed to find a better way to manage anemia in pediatric patients undergoing hemodialysis. Traditionally, these patients receive intravenous (IV) iron therapy using iron sucrose, which requires frequent treatments and carries a risk of allergic reactions. Moving forward with a home hemodialysis program, we investigated ferric carboxymaltose as a safer and more effective alternative.
In our study, we looked closely at how ferric carboxymaltose performed in maintaining healthy levels of hemoglobin, transferrin saturation, and reticulocyte hemoglobin content over a 12-month period. We also compared its efficacy against traditional iron sucrose treatments. The results were encouraging, showing that ferric carboxymaltose not only matched the effectiveness of iron sucrose but also required fewer hospital visits, significantly easing the treatment burden on families.
Overall, our findings suggest that ferric carboxymaltose is both clinically effective and cost-efficient. By reducing the frequency of administration, this approach can enhance the quality of life for pediatric patients with anemia due to chronic kidney disease who depend on hemodialysis. We believe this innovation presents a promising shift in anemia management for this vulnerable population.
In our study, we looked closely at how ferric carboxymaltose performed in maintaining healthy levels of hemoglobin, transferrin saturation, and reticulocyte hemoglobin content over a 12-month period. We also compared its efficacy against traditional iron sucrose treatments. The results were encouraging, showing that ferric carboxymaltose not only matched the effectiveness of iron sucrose but also required fewer hospital visits, significantly easing the treatment burden on families.
Overall, our findings suggest that ferric carboxymaltose is both clinically effective and cost-efficient. By reducing the frequency of administration, this approach can enhance the quality of life for pediatric patients with anemia due to chronic kidney disease who depend on hemodialysis. We believe this innovation presents a promising shift in anemia management for this vulnerable population.
9.5
Saved from anemia
Most Useful Review
Solgar's iron supplement was a lifesaver for my severe anemia. I was barely able to function, feeling exhausted and memory impaired. After months of taking various iron pills, I finally overcame anemia. Doctors advised me to continue taking iron after each menstrual cycle due to my significant blood loss. I can't pinpoint any drawbacks to this supplement; it has solely beneficial effects.
Pumpkin Seeds Pepitas
8
In our exploration of how protein treatments can improve anemia, we focused on the impact of romiplostim, a thrombopoietin receptor agonist, on patients suffering from aplastic anemia (AA) who were either refractory to or intolerant of eltrombopag (EPAG). We studied a group of 18 patients, most of whom had severe AA, who transitioned from EPAG to romiplostim for at least three months.
Remarkably, 72% of these patients responded positively to romiplostim, with many showing improvement in their blood cell counts within the first three months. Of these, half demonstrated a trilineage response, meaning their blood counts improved across multiple cell types. However, we noticed that those who initiated romiplostim a significant time after their initial AA diagnosis tended to struggle to respond effectively.
In instances where treatment with romiplostim was interrupted, we observed that some patients relapsed into thrombocytopenia, suggesting that romiplostim plays a critical role in maintaining blood counts. Overall, our findings indicate that romiplostim can be a valuable option for patients who do not benefit from other treatments, bringing renewed hope in the management of this challenging condition.
Remarkably, 72% of these patients responded positively to romiplostim, with many showing improvement in their blood cell counts within the first three months. Of these, half demonstrated a trilineage response, meaning their blood counts improved across multiple cell types. However, we noticed that those who initiated romiplostim a significant time after their initial AA diagnosis tended to struggle to respond effectively.
In instances where treatment with romiplostim was interrupted, we observed that some patients relapsed into thrombocytopenia, suggesting that romiplostim plays a critical role in maintaining blood counts. Overall, our findings indicate that romiplostim can be a valuable option for patients who do not benefit from other treatments, bringing renewed hope in the management of this challenging condition.
9.5
Helps iron deficiency
Most Useful Review
Amazing! It’s excellent for those who suffer from anaemia and iron deficiency. I always order it.
Ascorbic Acid
7
Vitamin C enhances iron absorption
We conducted a study to explore the impact of adding vitamin C-rich guava to a traditional meal of mungbean dal on children’s anemia in rural India. Our randomized controlled trial involved 200 school-aged children, many of whom were found to be anemic and iron-deficient. We aimed to see if this simple addition could improve their hemoglobin levels and overall iron status.
The children in our study were divided into two groups. One group enjoyed a meal of mungbean dal alone, while the other had the same meal but with fresh guava included. Our findings revealed that the addition of guava, packed with vitamin C, significantly increased hemoglobin levels and reduced anemia in the children consuming the fortified meal.
However, despite these positive outcomes in hemoglobin, we observed that body iron stores did not increase significantly. This suggests that while vitamin C can enhance iron absorption, the combination may not provide enough iron to boost overall iron storage in the body. Thus, enriching meals with vitamin C-rich foods like guava is a promising strategy to combat anemia among children.
The children in our study were divided into two groups. One group enjoyed a meal of mungbean dal alone, while the other had the same meal but with fresh guava included. Our findings revealed that the addition of guava, packed with vitamin C, significantly increased hemoglobin levels and reduced anemia in the children consuming the fortified meal.
However, despite these positive outcomes in hemoglobin, we observed that body iron stores did not increase significantly. This suggests that while vitamin C can enhance iron absorption, the combination may not provide enough iron to boost overall iron storage in the body. Thus, enriching meals with vitamin C-rich foods like guava is a promising strategy to combat anemia among children.
9.5
Increased iron levels
Most Useful Review
I purchased this to take alongside iron supplements as recommended by a professor, due to my lifelong struggle with anemia. Indeed, this method effectively and rapidly raises iron levels in the blood. Vitamin C helps oxidise iron for better absorption in the body. There’s plenty of powder in the jar to last a long time, and I sometimes add it to tea for a bit of tang. A quality product!
Vitamin C
7
Vitamin C enhances iron absorption
We conducted a study to explore the impact of adding vitamin C-rich guava to a traditional meal of mungbean dal on children’s anemia in rural India. Our randomized controlled trial involved 200 school-aged children, many of whom were found to be anemic and iron-deficient. We aimed to see if this simple addition could improve their hemoglobin levels and overall iron status.
The children in our study were divided into two groups. One group enjoyed a meal of mungbean dal alone, while the other had the same meal but with fresh guava included. Our findings revealed that the addition of guava, packed with vitamin C, significantly increased hemoglobin levels and reduced anemia in the children consuming the fortified meal.
However, despite these positive outcomes in hemoglobin, we observed that body iron stores did not increase significantly. This suggests that while vitamin C can enhance iron absorption, the combination may not provide enough iron to boost overall iron storage in the body. Thus, enriching meals with vitamin C-rich foods like guava is a promising strategy to combat anemia among children.
The children in our study were divided into two groups. One group enjoyed a meal of mungbean dal alone, while the other had the same meal but with fresh guava included. Our findings revealed that the addition of guava, packed with vitamin C, significantly increased hemoglobin levels and reduced anemia in the children consuming the fortified meal.
However, despite these positive outcomes in hemoglobin, we observed that body iron stores did not increase significantly. This suggests that while vitamin C can enhance iron absorption, the combination may not provide enough iron to boost overall iron storage in the body. Thus, enriching meals with vitamin C-rich foods like guava is a promising strategy to combat anemia among children.
9.5
Boosts immunity
Most Useful Review
Excellent quality vitamin C! I previously had anemia and felt tired; my doctor recommended vitamin C to enhance iron absorption. This product improved my immunity and overall health significantly!
Ester C
7
Vitamin C enhances iron absorption
We conducted a study to explore the impact of adding vitamin C-rich guava to a traditional meal of mungbean dal on children’s anemia in rural India. Our randomized controlled trial involved 200 school-aged children, many of whom were found to be anemic and iron-deficient. We aimed to see if this simple addition could improve their hemoglobin levels and overall iron status.
The children in our study were divided into two groups. One group enjoyed a meal of mungbean dal alone, while the other had the same meal but with fresh guava included. Our findings revealed that the addition of guava, packed with vitamin C, significantly increased hemoglobin levels and reduced anemia in the children consuming the fortified meal.
However, despite these positive outcomes in hemoglobin, we observed that body iron stores did not increase significantly. This suggests that while vitamin C can enhance iron absorption, the combination may not provide enough iron to boost overall iron storage in the body. Thus, enriching meals with vitamin C-rich foods like guava is a promising strategy to combat anemia among children.
The children in our study were divided into two groups. One group enjoyed a meal of mungbean dal alone, while the other had the same meal but with fresh guava included. Our findings revealed that the addition of guava, packed with vitamin C, significantly increased hemoglobin levels and reduced anemia in the children consuming the fortified meal.
However, despite these positive outcomes in hemoglobin, we observed that body iron stores did not increase significantly. This suggests that while vitamin C can enhance iron absorption, the combination may not provide enough iron to boost overall iron storage in the body. Thus, enriching meals with vitamin C-rich foods like guava is a promising strategy to combat anemia among children.
9.5
Indicators returned normal
Most Useful Review
I buy this vitamin C, as well as more than one jar, on my doctor's recommendation, alongside other medications such as iron and B complex for anemia. After retaking my tests, all indicators returned to normal, indicating that the treatment is effective. Henceforth, I've started taking it during the autumn-spring period to maintain my immunity.
Prenatal Multivitamins
9
We examined the connection between haptoglobin (Hp) gene variations and the risk of gestational iron-deficiency anemia (IDA) in pregnant women. Analyzing data from over 1,400 women, we found that those with the Hp 1-1 phenotype faced a notably higher risk of IDA, especially when their dietary iron intake fell short or if they didn’t use prenatal multivitamins.
Specifically, women not following recommended iron intake guidelines were four times more likely to develop IDA. This study highlights the importance of prenatal supplementation and proper dietary iron consumption for healthy pregnancies.
Specifically, women not following recommended iron intake guidelines were four times more likely to develop IDA. This study highlights the importance of prenatal supplementation and proper dietary iron consumption for healthy pregnancies.
9.5
Improved hemoglobin
Most Useful Review
I found these vitamins wonderful during my pregnancy and breastfeeding. I read the reviews while expecting and started taking them at seven months pregnant. My doctor approved the composition, and my hemoglobin returned to normal. The size of the tablet is manageable, and I appreciate the inclusion of iodine. Now, three months into breastfeeding, I continue to take these vitamins, and my hair is healthy and growing well. I feel energetic and less fatigued.
Omega 3 Fish Oil
We explored the effectiveness of adding omega-3 fish oil, specifically its components eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), along with Manuka honey, to conventional therapies in treating oxidative stress in children with β-thalassemia major. In this study, 165 pediatric patients were involved in a randomized, double-blind trial. They were divided into three groups: one received a combination of omega-3 and Manuka honey, while another group got just Manuka honey, and a third group followed standard treatment alone.
Throughout the ten-month study period, we measured various markers of oxidative stress and overall health in these children. Our findings revealed that the combination of omega-3 and Manuka honey showed more effectiveness in managing oxidative stress than either Manuka honey alone or the conventional treatment. This suggests that integrating omega-3 into their treatment plan could offer better outcomes for managing the health challenges associated with β-thalassemia.
Ultimately, our research highlights the potential role of omega-3 as a beneficial component in the treatment of anemia related to oxidative stress in pediatric patients. By addressing both oxidative stress and iron overload, we hope this approach leads to improved management strategies for young individuals dealing with this inherited condition.
Throughout the ten-month study period, we measured various markers of oxidative stress and overall health in these children. Our findings revealed that the combination of omega-3 and Manuka honey showed more effectiveness in managing oxidative stress than either Manuka honey alone or the conventional treatment. This suggests that integrating omega-3 into their treatment plan could offer better outcomes for managing the health challenges associated with β-thalassemia.
Ultimately, our research highlights the potential role of omega-3 as a beneficial component in the treatment of anemia related to oxidative stress in pediatric patients. By addressing both oxidative stress and iron overload, we hope this approach leads to improved management strategies for young individuals dealing with this inherited condition.
10
Excellent results
Most Useful Review
My daughter took it as prescribed for her anemia, starting with 2 tonnes per day for four months, followed by a month’s break, then continuing with 1 tonne per day for another four months. The result has been excellent.
Coenzyme Q10 Coq10
8
We explored the effects of coenzyme Q10 on anemia, particularly in the context ofDiamond-Blackfan anemia, a disorder linked to issues with red blood cell production. In our investigation, we examined how mitochondrial energy metabolism plays a critical role in the health of red blood cell progenitors.
Through a primary cell model, we suppressed the mitochondrial oxidative phosphorylation (OXPHOS) pathway, which led to complications in the differentiation of erythroid cells and disrupted ribosome production. Notably, the mutated genes associated with OXPHOS in patients with Diamond-Blackfan anemia contributed to this malfunction.
When we applied coenzyme Q10—known to activate the OXPHOS pathway—we observed significant improvements in the erythroid defects that arose from the suppression. This compound not only helped in rescuing the erythroid development but also boosted the expression of a crucial protein involved in ribosome biogenesis.
Overall, our study points to coenzyme Q10 as a promising candidate for addressing anemia arising from mitochondrial issues, emphasizing its potential therapeutic impact in conditions like Diamond-Blackfan anemia.
Through a primary cell model, we suppressed the mitochondrial oxidative phosphorylation (OXPHOS) pathway, which led to complications in the differentiation of erythroid cells and disrupted ribosome production. Notably, the mutated genes associated with OXPHOS in patients with Diamond-Blackfan anemia contributed to this malfunction.
When we applied coenzyme Q10—known to activate the OXPHOS pathway—we observed significant improvements in the erythroid defects that arose from the suppression. This compound not only helped in rescuing the erythroid development but also boosted the expression of a crucial protein involved in ribosome biogenesis.
Overall, our study points to coenzyme Q10 as a promising candidate for addressing anemia arising from mitochondrial issues, emphasizing its potential therapeutic impact in conditions like Diamond-Blackfan anemia.
8.8
Increased energy
Most Useful Review
Doctors Best High Absorption coQ10 has significantly boosted my energy levels. I have thalassemia anemia, which isn't treatable with medications, but this product is quite affordable and helps me a great deal.
Folic Acid
2
Folic acid plus micronutrients ineffective
We conducted a trial in rural India to see if adding multiple micronutrients to iron-folic acid improves anemia in young children. Over 1,300 children with mild-to-moderate anemia were divided into two groups: one received iron-folic acid alone, while the other got iron-folic acid plus micronutrients.
After 90 days, both groups showed no significant differences in hemoglobin levels or anemia cure rates. While compliance was high in both groups, our findings suggest that focusing on iron-folic acid alone may be sufficient for effective anemia recovery in these children.
After 90 days, both groups showed no significant differences in hemoglobin levels or anemia cure rates. While compliance was high in both groups, our findings suggest that focusing on iron-folic acid alone may be sufficient for effective anemia recovery in these children.
9.5
Combatting folate deficiency
Most Useful Review
After being diagnosed with folate anaemia, my doctor recommended this methylfolate, which has excellent digestibility and performance.
Zinc
8
Zinc improves anaemia outcomes
We set out to explore how zinc, through micronutrient powders (MNPs), influences anaemia in young children, particularly in Bangladesh, where high rates of anaemia persist. In a well-structured trial, we observed children aged 9-11 months receiving daily doses of MNPs for 24 weeks. Initially, a staggering 54.1% of these children had anaemia, characterized by low hemoglobin levels.
At the end of the study, anaemia prevalence decreased to 32.6%, indicating some positive effects of the MNPs, which included zinc as one of their components. However, while we found various factors associated with anaemia—like underweight status and frequent illness—it's crucial to note that we could not isolate the specific impact of zinc on anaemia from other nutritional interventions included in the powders.
Overall, we acknowledged that while MNPs contribute to addressing anaemia, they should be part of a broader strategy that encompasses other factors impacting health and nutrition. This comprehensive approach ensures effective prevention and control of anaemia in vulnerable populations.
At the end of the study, anaemia prevalence decreased to 32.6%, indicating some positive effects of the MNPs, which included zinc as one of their components. However, while we found various factors associated with anaemia—like underweight status and frequent illness—it's crucial to note that we could not isolate the specific impact of zinc on anaemia from other nutritional interventions included in the powders.
Overall, we acknowledged that while MNPs contribute to addressing anaemia, they should be part of a broader strategy that encompasses other factors impacting health and nutrition. This comprehensive approach ensures effective prevention and control of anaemia in vulnerable populations.
9.5
Improved anemia treatment
Most Useful Review
Top product! This zinc is an excellent form of assimilation and does not upset my stomach. I decided to try it after reading about its benefits, and it's now an essential supplement for me, especially in combination with copper. I take it with meals to address my anemia. The capsules are small, and the packaging is lovely.
Vitamin D
9
Our investigation centered on whether vitamin D levels play a significant role in iron deficiency anemia (IDA). We examined data from the National Health and Nutrition Examination Survey, which included over 3,700 participants, to explore the relationship between vitamin D and IDA.
Our findings indicated that higher levels of serum vitamin D are linked to a lower risk of developing IDA. Specifically, those in the highest quartile of vitamin D levels had a significantly reduced risk compared to those in the lowest quartile. Interestingly, this protective effect appeared to be more pronounced in women.
We also found a non-linear relationship, suggesting that the effects of vitamin D on anemia become more complex at different levels. This was further supported by a Mendelian randomization analysis, which provided genetic evidence for a causal connection between vitamin D and IDA.
Overall, our results suggest that adequate vitamin D levels could be important for preventing anemia, especially among women. However, further research is certainly needed to confirm these findings and to investigate the potential for vitamin D treatment in managing IDA directly.
Our findings indicated that higher levels of serum vitamin D are linked to a lower risk of developing IDA. Specifically, those in the highest quartile of vitamin D levels had a significantly reduced risk compared to those in the lowest quartile. Interestingly, this protective effect appeared to be more pronounced in women.
We also found a non-linear relationship, suggesting that the effects of vitamin D on anemia become more complex at different levels. This was further supported by a Mendelian randomization analysis, which provided genetic evidence for a causal connection between vitamin D and IDA.
Overall, our results suggest that adequate vitamin D levels could be important for preventing anemia, especially among women. However, further research is certainly needed to confirm these findings and to investigate the potential for vitamin D treatment in managing IDA directly.
9.5
Significant vitamin increase
Most Useful Review
My vitamin D rose from 14.2 to 45.3 ng/ml in 8 months, after I started taking 5000 IU alongside Omega-3. I noticed improvements in bone pain, hair loss, and energy levels after starting the supplement. Following my endocrinologist's advice, I adjusted the timing of my intake for better absorption. Vitamin D likely aided my recovery from coronavirus, and I aim to increase my levels further to enhance my health alongside managing my anaemia.
L Glutathione
9
Silymarin reduces iron overload effectively
We examined how silymarin, derived from silybum marianum, impacts iron overload in patients with β-thalassemia major undergoing treatment with desferrioxamine. Over nine months, patients who received silymarin alongside desferrioxamine saw marked reductions in ferritin, iron, and total iron-binding capacity compared to those taking a placebo.
Additionally, participants using silymarin experienced improved liver function and lowered hepcidin levels. This suggests that silymarin could effectively alleviate body iron burden, enhancing treatment outcomes for anemia in thalassemia patients.
Additionally, participants using silymarin experienced improved liver function and lowered hepcidin levels. This suggests that silymarin could effectively alleviate body iron burden, enhancing treatment outcomes for anemia in thalassemia patients.
9.5
Improved health overall
Most Useful Review
Glutathione is a powerful antioxidant and a very effective product. It supports liver health and prevents cell oxidation. The vegetarian capsule contains glutathione, milk thistle, and alpha lipoic acid. After two months of use, I've noticed significant benefits in skin brightness, reduced pigmentation, fewer wrinkles, and a resolution of my anemia, all while following a low-carb diet and avoiding sugar.
Fiber
9.5
Improves absorption rates
Most Useful Review
This is a good quality product. The combination of Methylfolate and B12 in active forms tastes great and is effective. I find that taking it sublingually helps with the absorption of B12, supporting my recovery from anaemia. I recommend it.
9.5
Perfectly suited
Most Useful Review
For years, I suffered from anaemia and struggled to find a suitable medication. This product worked perfectly for me with no side effects. I trust this brand for its quality and effectiveness.
Multivitamins
9.5
Easily digestible
Most Useful Review
This multivitamin is tailored for pregnant and breastfeeding mothers, chosen to supplement essential nutrients like iron, folic acid, and vitamin B. Being based on natural ingredients, it is easy to digest without any stomach discomfort, even in the morning. Once I began taking it, my energy became more stable and I felt less fatigued. I noticed a marked alleviation of my anemia symptoms, attributed to the appropriate iron content. One pill suffices for sufficient nutrition, making it easy to incorporate into my busy routine. I highly recommend it to mothers aiming to maintain their physical strength during pregnancy or post-birth.
10
Healed anemia
Most Useful Review
After many years of suffering from anemia, I have finally been healed. Gradually drinking supplements over a prolonged period has made all the difference.
Probiotics
9.5
Impressive results
Most Useful Review
For those suffering from anemia, this product is a remedy. I gave it to my sister, and the results were impressive after years of distress. We used two bottles, and if you find my comment helpful, please do not hesitate to try it. May God bless you with peace.
10
Highly effective
Most Useful Review
Best iron tablets ever! These are the only supplements that don’t upset my stomach and actually work! I was very anaemic and, after six weeks on these, my iron levels improved significantly. I simply added these to my routine, and now I feel fantastic. I've even avoided transfusions. I hope this helps!
Ginkgo Biloba
8.8
Sleep improvement
Most Useful Review
The strength of these capsules has greatly improved my blood circulation and energy. The pain in my veins ceased, and my hand numbness reduced significantly. I now fall asleep within 45 minutes, whereas I previously struggled for two hours due to insomnia. Ginkgo pills are essential for managing diabetes and hypertension, plus they're beneficial for the elderly and anyone suffering from anemia.
8.8
Enhanced sleep
Most Useful Review
These capsules are excellent! They have improved my blood circulation and energy immensely, making the pain in my veins disappear. Also, my hand numbness has reduced. I can now sleep within 45 minutes instead of two hours due to my insomnia. I highly recommend Ginkgo for those with diabetes and hypertension, as well as for the elderly and those with anemia.
Selenium
8.8
Increased energy levels
Most Useful Review
Selenium is a vital mineral for our body's full functioning and must be taken as prescribed by a doctor, as high doses can be toxic! I experienced general weakness, including muscle weakness, anemia, and frequent colds. My doctor advised me to take selenium for three months, a tablet each morning. After a month, I felt energised and could engage in sports comfortably, as my muscles responded well to the effort. This progress brought me immense joy! Wishing all good health and enthusiasm for sports!
8.8
Improved sports performance
Most Useful Review
In one word—selenium! This essential mineral must be taken under a doctor’s direction as it can be toxic in high doses! I experienced general weakness, muscle weakness, anemia, and frequent colds. After consulting my doctor, I took selenium for three months, one tablet each morning. After a month of usage, I felt invigorated and comfortable during sports, with my muscles responding well to the effort. This made me very happy! Here’s to health and delight from sports!
L Lysine
7.8
Positive trend
Most Useful Review
I am using it as part of my treatment for anemia, as I have low hemoglobin and ferritin. Besides iron supplements and vitamin C, my doctor advised lysine, as I seem to lack protein, crucial for iron absorption. I've been using all these supplements for two months, and while I have not experienced side effects, my iron levels have returned to normal. Healing takes time, but I see a positive trend, and while I don’t believe lysine alone is responsible, it certainly helps.
9.5
Improved blood markers
Most Useful Review
I took it to enhance iron absorption, and in just a month, my results showed significant improvement. It appears this product is effective; I would recommend it to anyone undergoing treatment for their anemia.
Childrens Herbs
9.5
Improved hemoglobin
Most Useful Review
Excellent tool for enhancing immunity. I tried this product due to my child's anemia, and within a month, their hemoglobin returned to normal. They caught a virus twice, but the illness was less severe and free of complications. I’m very pleased and plan to continue using it regularly during the autumn-winter period.
9.5
Iron deficiency addressed
Most Useful Review
I was diagnosed with iron deficiency anaemia. After taking one tablet daily during breakfast for a month, in addition to a multivitamin, my deficiencies were filled. This product comes highly recommended by friends, and I’m very grateful for its quality and effectiveness. The sealed packaging ensures freshness and reliability.
Alpha Lipoic Acid
9.5
Helps with anemia
Most Useful Review
Excellent product! It effectively helps with my anemia, and the tablets are small and easy to swallow.
8
Caution for anemia
Most Useful Review
While I found this product enjoyable and effective, I became aware of a crucial detail. Alpha lipoic acid can eliminate not only harmful metals but also beneficial ones like iron, which is significant for those prone to anemia like me. After two and a half months, my iron levels dropped. Use it cautiously if you have anemia!