Last update
3/26/2026
Reviewed By
Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 1 Research
7
USERS' SCORE
Good
Based on 10 Reviews
8.2
Supplement Facts
Serving Size: 2 Tablets
Amount Per Serving
%DV
Calcium (elemental) (from 2,775 mg complex of Calcium Carbonate, Calcium Citrate, Calcium Ascorbate)
1 g (1,000 mg)
77%
Magnesium (elemental) (from 928 mg complex of Magnesium Oxide, Magnesium Citrate, Magnesium Ascorbate)
500 mg
119%
Top Medical Research Studies
7
We explored how magnesium affects our immune response, particularly in relation to fighting off influenza. By examining how magnesium levels influence T cell function, we noticed that lower levels of magnesium in the body could hinder the T cell receptor (TCR) activation process. This is significant because TCR activation is crucial for mounting an effective immune response against viruses like influenza.
Our findings revealed that insufficient magnesium decreases the activation of important immune cells, specifically CD8 T cells, which are vital for responding to infections. This was further demonstrated in mice where reduced serum magnesium concentrations led to weaker immune responses and more severe illness from influenza A virus.
Overall, we observed that magnesium not only serves as an essential cofactor in cellular processes but also plays a direct role in maintaining strong immune function. Ensuring an adequate intake of magnesium is therefore important for enhancing our ability to combat viral infections effectively.
Our findings revealed that insufficient magnesium decreases the activation of important immune cells, specifically CD8 T cells, which are vital for responding to infections. This was further demonstrated in mice where reduced serum magnesium concentrations led to weaker immune responses and more severe illness from influenza A virus.
Overall, we observed that magnesium not only serves as an essential cofactor in cellular processes but also plays a direct role in maintaining strong immune function. Ensuring an adequate intake of magnesium is therefore important for enhancing our ability to combat viral infections effectively.
Read More
Most Useful Reviews
9
Improved digestion
The vitamins arrived quickly and are of excellent quality. The tablets are large, containing two doses each, which can be split if needed. I learned that calcium can be taken during the day, but magnesium is better at night. Since I began taking this combination, I have noticed improvements in digestion and a reduction in heartburn. Overall, I feel my bones and immunity have greatly benefited.
Read More
7.5
Flu recovery helped
I've been using this for months and love it. It was particularly beneficial when I contracted the flu that spread through my family. Both my spouse and child had severe cases, and while my child is still recovering, I was feeling unwell with chills, fever, and aches on Tuesday.
Read More
9
Cramps eliminated
Good day. I'm sharing my feedback on this product, which I have recommended to family. I suffer from calcium deficiency confirmed by tests and experience leg cramps. NOW® Calcium and Magnesium supports essential physiological functions. Since taking this, my teeth have improved significantly, and the convulsions have ceased. The price is excellent for the large quantity, and it caused no side effects. The minerals are easy to digest.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 1 Research
7
- All Researches
7
We explored how magnesium affects our immune response, particularly in relation to fighting off influenza. By examining how magnesium levels influence T cell function, we noticed that lower levels of magnesium in the body could hinder the T cell receptor (TCR) activation process. This is significant because TCR activation is crucial for mounting an effective immune response against viruses like influenza.
Our findings revealed that insufficient magnesium decreases the activation of important immune cells, specifically CD8 T cells, which are vital for responding to infections. This was further demonstrated in mice where reduced serum magnesium concentrations led to weaker immune responses and more severe illness from influenza A virus.
Overall, we observed that magnesium not only serves as an essential cofactor in cellular processes but also plays a direct role in maintaining strong immune function. Ensuring an adequate intake of magnesium is therefore important for enhancing our ability to combat viral infections effectively.
Our findings revealed that insufficient magnesium decreases the activation of important immune cells, specifically CD8 T cells, which are vital for responding to infections. This was further demonstrated in mice where reduced serum magnesium concentrations led to weaker immune responses and more severe illness from influenza A virus.
Overall, we observed that magnesium not only serves as an essential cofactor in cellular processes but also plays a direct role in maintaining strong immune function. Ensuring an adequate intake of magnesium is therefore important for enhancing our ability to combat viral infections effectively.
Read More
User Reviews
USERS' SCORE
Good
Based on 10 Reviews
8.2
- All Reviews
- Positive Reviews
- Negative Reviews
9
Improved digestion
The vitamins arrived quickly and are of excellent quality. The tablets are large, containing two doses each, which can be split if needed. I learned that calcium can be taken during the day, but magnesium is better at night. Since I began taking this combination, I have noticed improvements in digestion and a reduction in heartburn. Overall, I feel my bones and immunity have greatly benefited.
Read More
7.5
Flu recovery helped
I've been using this for months and love it. It was particularly beneficial when I contracted the flu that spread through my family. Both my spouse and child had severe cases, and while my child is still recovering, I was feeling unwell with chills, fever, and aches on Tuesday.
Read More
9
Cramps eliminated
Good day. I'm sharing my feedback on this product, which I have recommended to family. I suffer from calcium deficiency confirmed by tests and experience leg cramps. NOW® Calcium and Magnesium supports essential physiological functions. Since taking this, my teeth have improved significantly, and the convulsions have ceased. The price is excellent for the large quantity, and it caused no side effects. The minerals are easy to digest.
Read More
7.5
Improved health
The supplement is quite large, making it difficult for me to swallow. However, it's beneficial as I can take calcium and magnesium together. I have heard that excessive calcium intake isn't advisable, so I've focused on magnesium. Since I started taking this, my dizziness has improved significantly, and I no longer require medication. I aim to continue for my health.
Read More
7.5
Teeth health improved
NOW® Calcium and Magnesium combine two essential minerals that support various physiological processes. Both are necessary for proper nerve, muscle, and circulatory system function. Initially, my family struggled with swallowing the tablets, so I crushed them for the kids. Since starting this supplement, their dental issues have considerably improved, and persistent problems have resolved.
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Frequently Asked Questions
7.5
Reduced muscle spasms
Calcium and magnesium form the foundation of bone tissue, significantly impacting its mineralisation and density. I experience muscle spasms, and this combination has substantially reduced the cramps in my calf muscles.
7.5
Cramps alleviated
6 people found this helpful
Calcium is vital for bone and heart health, with a recommended daily dose of 1000 mg. For optimal absorption, I also take vitamin D3 or magnesium with pyridoxine (vitamin B6). Both calcium and magnesium are crucial for the normal functioning of nerves, muscles, and blood vessels. After a few weeks of this vitamin complex, I’ve noticed significant improvements, particularly in reducing night-time calf muscle cramps and twitching.
7.5
Convulsions reduced
The packaging is high quality, and the tablets are larger than average. The calcium to magnesium ratio is optimal. I began this specific magnesium for my husband to aid his convulsions. After a month, significant improvement was apparent; his convulsions almost disappeared, and his sleep quality improved. Additionally, calcium intake is crucial for someone like him, who rarely consumes calcium-rich foods.
9
Cramps eliminated
Good day. I'm sharing my feedback on this product, which I have recommended to family. I suffer from calcium deficiency confirmed by tests and experience leg cramps. NOW® Calcium and Magnesium supports essential physiological functions. Since taking this, my teeth have improved significantly, and the convulsions have ceased. The price is excellent for the large quantity, and it caused no side effects. The minerals are easy to digest.
7.5
Improved health
The supplement is quite large, making it difficult for me to swallow. However, it's beneficial as I can take calcium and magnesium together. I have heard that excessive calcium intake isn't advisable, so I've focused on magnesium. Since I started taking this, my dizziness has improved significantly, and I no longer require medication. I aim to continue for my health.
7.5
Joint pain relief
Calcium and magnesium support bone health. This manufacturer's Calcium and Magnesium combines two essential minerals that work together to support various important physiological processes. Both minerals are vital for the normal functioning of the body's nervous, muscular, and circulatory systems, as well as maintaining proper fluid balance. I took two tablets a day for three months. My joint pain has reduced, and I've begun to sleep better. There were no side effects, although the tablets were large for me - I crushed them and took them with meals.
7
We explored how magnesium affects our immune response, particularly in relation to fighting off influenza. By examining how magnesium levels influence T cell function, we noticed that lower levels of magnesium in the body could hinder the T cell receptor (TCR) activation process. This is significant because TCR activation is crucial for mounting an effective immune response against viruses like influenza.
Our findings revealed that insufficient magnesium decreases the activation of important immune cells, specifically CD8 T cells, which are vital for responding to infections. This was further demonstrated in mice where reduced serum magnesium concentrations led to weaker immune responses and more severe illness from influenza A virus.
Overall, we observed that magnesium not only serves as an essential cofactor in cellular processes but also plays a direct role in maintaining strong immune function. Ensuring an adequate intake of magnesium is therefore important for enhancing our ability to combat viral infections effectively.
Our findings revealed that insufficient magnesium decreases the activation of important immune cells, specifically CD8 T cells, which are vital for responding to infections. This was further demonstrated in mice where reduced serum magnesium concentrations led to weaker immune responses and more severe illness from influenza A virus.
Overall, we observed that magnesium not only serves as an essential cofactor in cellular processes but also plays a direct role in maintaining strong immune function. Ensuring an adequate intake of magnesium is therefore important for enhancing our ability to combat viral infections effectively.
References
- Kanellopoulou C, George AB, Masutani E, Cannons JL, Ravell JC, et al. Mg regulation of kinase signaling and immune function. J Exp Med. 2019;216:1828. 10.1084/jem.20181970
Data last updated:
