' 
SCIENTIFIC SCORE
Questionable
Based on 5 Researches
6
USERS' SCORE
Good
Based on 2 Reviews
8.5
Supplement Facts
Serving Size: 2 Tablets
Amount Per Serving
%DV
Calcium (elemental) (from 2,775 mg complex of Calcium Carbonate, Calcium Citrate, Calcium Ascorbate)
1 g (1,000 mg)
77%
Magnesium (elemental) (from 928 mg complex of Magnesium Oxide, Magnesium Citrate, Magnesium Ascorbate)
500 mg
119%
Top Medical Research Studies
4
Magnesium shows promise in thyroid recovery
Proof of concept of the WOMED model of benign thyroid disease: Restitution of thyroid morphology after correction of physical and psychological stressors and magnesium supplementation.
Study highlights mixed effectiveness
We set out to investigate how magnesium, along with selenium and coenzyme Q10, could influence hypothyroidism in patients with benign thyroid diseases. Our approach included a small group of eight patients—five with hyperthyroidism and three with hypothyroidism—who received additional treatment aimed at addressing both their thyroid condition and related physical and psychological stresses.
Over a period of 2 to 4 years, we observed some significant changes. Initially, we focused on correcting musculoskeletal issues, followed by addressing stress. As a result, we noted that thyroid morphology normalized in many cases, which was confirmed through ultrasound examinations. Interestingly, we also saw a reduction in thyroid antibody levels for most patients.
However, we must be transparent about our findings. While magnesium and the other supplements showed promise, there were two cases of chronic thyroiditis that did not respond positively to treatment, possibly due to long-standing fibrosis. This indicates that while magnesium may play a role in thyroid health, its effectiveness can vary significantly based on individual circumstances and the duration of the thyroid condition.
Over a period of 2 to 4 years, we observed some significant changes. Initially, we focused on correcting musculoskeletal issues, followed by addressing stress. As a result, we noted that thyroid morphology normalized in many cases, which was confirmed through ultrasound examinations. Interestingly, we also saw a reduction in thyroid antibody levels for most patients.
However, we must be transparent about our findings. While magnesium and the other supplements showed promise, there were two cases of chronic thyroiditis that did not respond positively to treatment, possibly due to long-standing fibrosis. This indicates that while magnesium may play a role in thyroid health, its effectiveness can vary significantly based on individual circumstances and the duration of the thyroid condition.
Read More
9
Magnesium improves hypothyroid inflammation
Effect of magnesium sulfate and thyroxine on inflammatory markers in a rat model of hypothyroidism.
Combines treatments complicates results
We explored the interaction between magnesium sulfate and levothyroxine in managing inflammation related to hypothyroidism. In this study, we used 60 male rats, dividing them into six different groups. These included normals, those given magnesium, hypothyroid rats, and various combinations of treatments with levothyroxine and magnesium.
Our findings showed that hypothyroidism led to an increase in inflammatory markers such as C-reactive protein and interleukin-6, while decreasing vital thyroid hormones. When we treated hypothyroid rats with either levothyroxine or magnesium, these inflammatory markers significantly decreased.
Notably, the rats that received a combination of both treatments experienced the most significant reduction in inflammation. This suggests that chronic low-grade inflammation in hypothyroid conditions might elevate the risk of cardiovascular diseases. Overall, using magnesium and levothyroxine together seems to be more effective in reducing inflammation compared to either treatment alone.
Our findings showed that hypothyroidism led to an increase in inflammatory markers such as C-reactive protein and interleukin-6, while decreasing vital thyroid hormones. When we treated hypothyroid rats with either levothyroxine or magnesium, these inflammatory markers significantly decreased.
Notably, the rats that received a combination of both treatments experienced the most significant reduction in inflammation. This suggests that chronic low-grade inflammation in hypothyroid conditions might elevate the risk of cardiovascular diseases. Overall, using magnesium and levothyroxine together seems to be more effective in reducing inflammation compared to either treatment alone.
Read More
3
Calcium levels in hypothyroidism
Investigating salivary concentration of calcium ion in hypothyroidism.
Investigated calcium's link to hypothyroidism
We aimed to understand how calcium levels in saliva are affected in individuals with hypothyroidism. As one of the most common thyroid disorders, hypothyroidism can lead to various oral health issues, including a higher likelihood of dental caries and periodontal disease.
Our study measured the salivary calcium levels in patients diagnosed with hypothyroidism and found that these levels were significantly lower compared to healthy individuals. It's important to note, however, that we did not find any meaningful connections between the salivary calcium concentrations and the levels of thyroid hormones (TSH and T4) in the blood.
While a decrease in salivary calcium might explain the increased dental problems in hypothyroidism patients, the study did not explore any potential benefits of calcium treatment for this condition. Thus, it remains unclear whether calcium supplementation could effectively improve the overall health outcomes associated with hypothyroidism.
Our study measured the salivary calcium levels in patients diagnosed with hypothyroidism and found that these levels were significantly lower compared to healthy individuals. It's important to note, however, that we did not find any meaningful connections between the salivary calcium concentrations and the levels of thyroid hormones (TSH and T4) in the blood.
While a decrease in salivary calcium might explain the increased dental problems in hypothyroidism patients, the study did not explore any potential benefits of calcium treatment for this condition. Thus, it remains unclear whether calcium supplementation could effectively improve the overall health outcomes associated with hypothyroidism.
Read More
Most Useful Reviews
8.8
Improving thyroid levels
On my endocrinologist's advice, I take it alongside vitamin D3 and Omega-3 for my hypothyroidism. My analyses are gradually approaching normal.
Read More
8
Calcium and magnesium aid
This supplement combines calcium and magnesium, which I need due to my hypothyroidism. I also took it while breastfeeding. The tablets are quite large, but I've gotten used to them.
Read More
Medical Researches
SCIENTIFIC SCORE
Questionable
Based on 5 Researches
6
9
Magnesium improves hypothyroid inflammation
Effect of magnesium sulfate and thyroxine on inflammatory markers in a rat model of hypothyroidism.
Combines treatments complicates results
We explored the interaction between magnesium sulfate and levothyroxine in managing inflammation related to hypothyroidism. In this study, we used 60 male rats, dividing them into six different groups. These included normals, those given magnesium, hypothyroid rats, and various combinations of treatments with levothyroxine and magnesium.
Our findings showed that hypothyroidism led to an increase in inflammatory markers such as C-reactive protein and interleukin-6, while decreasing vital thyroid hormones. When we treated hypothyroid rats with either levothyroxine or magnesium, these inflammatory markers significantly decreased.
Notably, the rats that received a combination of both treatments experienced the most significant reduction in inflammation. This suggests that chronic low-grade inflammation in hypothyroid conditions might elevate the risk of cardiovascular diseases. Overall, using magnesium and levothyroxine together seems to be more effective in reducing inflammation compared to either treatment alone.
Our findings showed that hypothyroidism led to an increase in inflammatory markers such as C-reactive protein and interleukin-6, while decreasing vital thyroid hormones. When we treated hypothyroid rats with either levothyroxine or magnesium, these inflammatory markers significantly decreased.
Notably, the rats that received a combination of both treatments experienced the most significant reduction in inflammation. This suggests that chronic low-grade inflammation in hypothyroid conditions might elevate the risk of cardiovascular diseases. Overall, using magnesium and levothyroxine together seems to be more effective in reducing inflammation compared to either treatment alone.
Read More
7
Calcium's role in thyroiditis
A case of reversible hypoparathyroidism in a patient with Riedel's thyroiditis treated with glucocorticoids.
Insight into hypoparathyroidism treatment
We explored the case of a 48-year-old woman who faced compressive symptoms due to a rapidly growing goiter, tied to her existing hypothyroidism. Despite her hypoparathyroidism being revealed through biological tests, she did not exhibit any signs of hypocalcemia initially.
The treatment she received included levothyroxine, calcium, and alfacalcidol, but a complete thyroidectomy was deemed unnecessary due to the tumor’s rigid adhesion to nearby structures. Upon histopathological examination, her condition was identified as Riedel’s thyroiditis. We watched as the introduction of glucocorticoids resulted in a significant reduction of symptoms and shrinkage of the thyroid gland.
Notably, after discontinuation of the vitamin and calcium supplementation, her serum calcium and parathyroid hormone levels normalized. This suggests that, in some instances, hypoparathyroidism can remain asymptomatic, especially under conditions like Riedel's thyroiditis. Furthermore, early glucocorticoid treatment seems valuable in addressing associated fibrosclerosis and restoring parathyroid function.
While calcium was part of the therapeutic strategy, it is challenging to ascertain its isolated effect due to the combination with other treatments in this specific case.
The treatment she received included levothyroxine, calcium, and alfacalcidol, but a complete thyroidectomy was deemed unnecessary due to the tumor’s rigid adhesion to nearby structures. Upon histopathological examination, her condition was identified as Riedel’s thyroiditis. We watched as the introduction of glucocorticoids resulted in a significant reduction of symptoms and shrinkage of the thyroid gland.
Notably, after discontinuation of the vitamin and calcium supplementation, her serum calcium and parathyroid hormone levels normalized. This suggests that, in some instances, hypoparathyroidism can remain asymptomatic, especially under conditions like Riedel's thyroiditis. Furthermore, early glucocorticoid treatment seems valuable in addressing associated fibrosclerosis and restoring parathyroid function.
While calcium was part of the therapeutic strategy, it is challenging to ascertain its isolated effect due to the combination with other treatments in this specific case.
Read More
7
Magnesium's role in hypothyroidism
The Effect of Some Micronutrients Multi-Supplementation on Thyroid Function, Metabolic Features and Quality of Life in Patients Treating With Levothyroxine and Vitamin D: A Double-blind, Randomized Controlled Trial.
Limited isolated magnesium assessment
We explored how magnesium, as part of a broader supplementation strategy, influences thyroid function and overall well-being in patients with hypothyroidism. In a well-structured study, 104 individuals receiving traditional treatment with levothyroxine and vitamin D were randomly divided into two groups. One group received a combination of essential micronutrients, including magnesium, while the other received placebos over an 8-week period.
Our observations highlighted changes in insulin resistance and quality of life after the intervention, suggesting that micronutrient supplementation could have a bearing on these aspects of health. However, the specifics regarding magnesium's isolated effect on thyroid function were less clear due to the multi-nutritional approach taken in this trial.
While we acknowledge promising results related to quality of life, we must clarify that the study does not provide concrete evidence that magnesium alone significantly improves thyroid function. Further, more focused clinical trials are necessary to ascertain the role of magnesium, allowing for a better understanding of its potential benefits in hypothyroid patients.
Our observations highlighted changes in insulin resistance and quality of life after the intervention, suggesting that micronutrient supplementation could have a bearing on these aspects of health. However, the specifics regarding magnesium's isolated effect on thyroid function were less clear due to the multi-nutritional approach taken in this trial.
While we acknowledge promising results related to quality of life, we must clarify that the study does not provide concrete evidence that magnesium alone significantly improves thyroid function. Further, more focused clinical trials are necessary to ascertain the role of magnesium, allowing for a better understanding of its potential benefits in hypothyroid patients.
Read More
4
Magnesium shows promise in thyroid recovery
Proof of concept of the WOMED model of benign thyroid disease: Restitution of thyroid morphology after correction of physical and psychological stressors and magnesium supplementation.
Study highlights mixed effectiveness
We set out to investigate how magnesium, along with selenium and coenzyme Q10, could influence hypothyroidism in patients with benign thyroid diseases. Our approach included a small group of eight patients—five with hyperthyroidism and three with hypothyroidism—who received additional treatment aimed at addressing both their thyroid condition and related physical and psychological stresses.
Over a period of 2 to 4 years, we observed some significant changes. Initially, we focused on correcting musculoskeletal issues, followed by addressing stress. As a result, we noted that thyroid morphology normalized in many cases, which was confirmed through ultrasound examinations. Interestingly, we also saw a reduction in thyroid antibody levels for most patients.
However, we must be transparent about our findings. While magnesium and the other supplements showed promise, there were two cases of chronic thyroiditis that did not respond positively to treatment, possibly due to long-standing fibrosis. This indicates that while magnesium may play a role in thyroid health, its effectiveness can vary significantly based on individual circumstances and the duration of the thyroid condition.
Over a period of 2 to 4 years, we observed some significant changes. Initially, we focused on correcting musculoskeletal issues, followed by addressing stress. As a result, we noted that thyroid morphology normalized in many cases, which was confirmed through ultrasound examinations. Interestingly, we also saw a reduction in thyroid antibody levels for most patients.
However, we must be transparent about our findings. While magnesium and the other supplements showed promise, there were two cases of chronic thyroiditis that did not respond positively to treatment, possibly due to long-standing fibrosis. This indicates that while magnesium may play a role in thyroid health, its effectiveness can vary significantly based on individual circumstances and the duration of the thyroid condition.
Read More
3
Calcium levels in hypothyroidism
Investigating salivary concentration of calcium ion in hypothyroidism.
Investigated calcium's link to hypothyroidism
We aimed to understand how calcium levels in saliva are affected in individuals with hypothyroidism. As one of the most common thyroid disorders, hypothyroidism can lead to various oral health issues, including a higher likelihood of dental caries and periodontal disease.
Our study measured the salivary calcium levels in patients diagnosed with hypothyroidism and found that these levels were significantly lower compared to healthy individuals. It's important to note, however, that we did not find any meaningful connections between the salivary calcium concentrations and the levels of thyroid hormones (TSH and T4) in the blood.
While a decrease in salivary calcium might explain the increased dental problems in hypothyroidism patients, the study did not explore any potential benefits of calcium treatment for this condition. Thus, it remains unclear whether calcium supplementation could effectively improve the overall health outcomes associated with hypothyroidism.
Our study measured the salivary calcium levels in patients diagnosed with hypothyroidism and found that these levels were significantly lower compared to healthy individuals. It's important to note, however, that we did not find any meaningful connections between the salivary calcium concentrations and the levels of thyroid hormones (TSH and T4) in the blood.
While a decrease in salivary calcium might explain the increased dental problems in hypothyroidism patients, the study did not explore any potential benefits of calcium treatment for this condition. Thus, it remains unclear whether calcium supplementation could effectively improve the overall health outcomes associated with hypothyroidism.
Read More
User Reviews
USERS' SCORE
Good
Based on 2 Reviews
8.5
8.8
Improving thyroid levels
On my endocrinologist's advice, I take it alongside vitamin D3 and Omega-3 for my hypothyroidism. My analyses are gradually approaching normal.
8
Calcium and magnesium aid
This supplement combines calcium and magnesium, which I need due to my hypothyroidism. I also took it while breastfeeding. The tablets are quite large, but I've gotten used to them.
