We conducted a double-blind, placebo-controlled clinical trial to investigate the effects of magnesium supplementation on insomnia in elderly individuals. Our study involved 46 participants who were assigned either to receive 500 mg of magnesium daily or a placebo for a duration of 8 weeks.
Throughout the study, we employed various questionnaires, including the Insomnia Severity Index (ISI), to evaluate the participants' sleep quality both before and after the treatment period. We also monitored the intake of other nutrients and performed blood tests to assess hormone levels related to sleep.
The results showed that magnesium supplementation led to significant improvements in areas such as sleep efficiency, sleep onset timing, and overall insomnia severity. We observed increases in serum levels of melatonin and changes in cortisol and renin levels, indicating a physiological response that could enhance sleep quality.
Overall, it seems that supplementing with magnesium has the potential to improve sleep for older adults struggling with insomnia. This finding could pave the way for new, accessible treatment options for those affected by sleep disorders.
Read More
4
Magnesium shows limited sleep benefits
Oral magnesium supplementation for insomnia in older adults: a Systematic Review & Meta-Analysis.
We explored the effects of magnesium supplementation on insomnia in older adults through a systematic review and meta-analysis. Our investigation included several studies that compared magnesium with a placebo or no treatment.
We found three randomized control trials involving 151 older adults across three countries. The pooled results indicated that individuals taking magnesium had a notable decrease in sleep onset latency, averaging a reduction of 17.36 minutes compared to those on placebo. However, the improvement in total sleep time, which increased by 16.06 minutes in the magnesium group, did not reach statistical significance.
Despite these findings, we must emphasize that the overall quality of the research is below standards necessary for making firm recommendations. All studies reviewed showed a moderate to high risk of bias, and the evidence quality ranged from low to very low. Nonetheless, magnesium is an affordable and widely accessible option for those struggling with insomnia symptoms, suggesting it may be a reasonable consideration for some older adults.
Read More
8
Magnesium may reduce daytime sleepiness
Magnesium Intake and Sleep Disorder Symptoms: Findings from the Jiangsu Nutrition Study of Chinese Adults at Five-Year Follow-Up.
We set out to explore how dietary magnesium might impact symptoms of insomnia, such as falling asleep during the day and snoring at night. Our study included a significant sample of 1,487 adults from the Jiangsu Nutrition Study, which allowed us to gather valuable information about their magnesium intake and sleep experiences. Over five years, we assessed participants' magnesium consumption through detailed food records and later examined their sleep patterns via a questionnaire.
Our findings revealed that the average magnesium intake among participants was 332.5 mg per day. Interestingly, we found that around 5.3% reported falling asleep during the day, 13.2% faced daytime sleepiness, and 35.7% experienced snoring at night. Rising through the quartiles of magnesium intake, we observed a promising decrease in the chance of women experiencing daytime falling asleep; however, this effect wasn’t mirrored in men. It’s crucial to note that we didn’t find significant associations between magnesium intake and daytime sleepiness or night snoring for either gender.
Overall, it seems that dietary magnesium might offer long-term benefits in reducing daytime sleepiness in women, while more research could clarify its effects on other symptoms. This makes magnesium an interesting dietary consideration for those seeking to improve their sleep quality.
Read More
Most Useful Reviews
9
Improved sleep quality
7 people found this helpful
Wonderful calcium! I began taking this regularly due to my physician's recommendation. It has no side effects and is well absorbed, which I can tell by the improvement in my nails. After years of dealing with insomnia, I've begun to sleep better and feel calmer, possibly thanks to the magnesium. My husband and son now use it too. I've learnt calcium should be taken daily, making this a regular purchase for our health.
Read More
7.5
Relieves stress
5 people found this helpful
I love magnesium! After using it for a long time, I find it really helps relax my muscles and eases cramps. I've recommended it to my sister and friends, and they swear by it too. Magnesium is vital for the nervous system, reducing anxiety and fatigue and helping with symptoms like insomnia and nervousness. It's crucial for maintaining a balanced mood during stressful times.
Read More
9
Supports insomnia relief
4 people found this helpful
I recommend this! I’ve been taking it for a long time as it helps relax my muscles and alleviate insomnia. Magnesium serves as a natural stress reliever, which is crucial for my well-being.
We explored the potential benefits of a supplement containing magnesium, melatonin, and vitamin B complex in treating insomnia. The study involved 60 patients diagnosed with insomnia, who were divided into a study group and a control group. Over three months, the study group received a daily dose of the supplement, while the control group did not receive it.
At the start, both groups had similar levels of insomnia, indicated by their scores on the Athens insomnia scale. However, after three months of supplementation, the study group showed a significant improvement, with their insomnia scores decreasing, indicating mild insomnia. In contrast, the control group’s scores remained stable, suggesting they continued to experience moderate insomnia.
Although magnesium was part of the supplement, the study design makes it challenging to isolate its specific effects on insomnia. Nevertheless, we observed that combining magnesium with melatonin and vitamin B complex potentially enhances sleep quality for those struggling with insomnia.
Read More
9
Magnesium improves elderly insomnia
The effect of magnesium supplementation on primary insomnia in elderly: A double-blind placebo-controlled clinical trial.
We conducted a double-blind, placebo-controlled clinical trial to investigate the effects of magnesium supplementation on insomnia in elderly individuals. Our study involved 46 participants who were assigned either to receive 500 mg of magnesium daily or a placebo for a duration of 8 weeks.
Throughout the study, we employed various questionnaires, including the Insomnia Severity Index (ISI), to evaluate the participants' sleep quality both before and after the treatment period. We also monitored the intake of other nutrients and performed blood tests to assess hormone levels related to sleep.
The results showed that magnesium supplementation led to significant improvements in areas such as sleep efficiency, sleep onset timing, and overall insomnia severity. We observed increases in serum levels of melatonin and changes in cortisol and renin levels, indicating a physiological response that could enhance sleep quality.
Overall, it seems that supplementing with magnesium has the potential to improve sleep for older adults struggling with insomnia. This finding could pave the way for new, accessible treatment options for those affected by sleep disorders.
Read More
9
Magnesium may aid sleep quality
The effect of melatonin, magnesium, and zinc on primary insomnia in long-term care facility residents in Italy: a double-blind, placebo-controlled clinical trial.
We conducted a double-blind, placebo-controlled clinical trial in a long-term care facility in Italy to explore whether nightly doses of melatonin, magnesium, and zinc could benefit residents suffering from primary insomnia. Our study involved 43 participants, who were either given a combined supplement of these nutrients or a placebo for eight weeks.
The primary objective was to measure sleep quality using the Pittsburgh Sleep Quality Index, while we also considered secondary indicators like daytime sleepiness and overall quality of life. The results revealed that the combined approach of melatonin, magnesium, and zinc appeared to improve both sleep and quality of life for residents struggling with insomnia.
However, since magnesium was tested alongside two other supplements, we cannot clearly attribute the benefits directly to magnesium alone. Overall, the findings suggest a positive effect on sleep quality and well-being for long-term care residents dealing with insomnia, but we must be cautious in isolating each nutrient's individual effectiveness.
Read More
8
Magnesium improves insomnia in diabetes
Effects of magnesium and potassium supplementation on insomnia and sleep hormones in patients with diabetes mellitus.
We conducted a randomized controlled trial focusing on individuals with diabetes who struggle with insomnia. Over two months, we examined the effects of magnesium and potassium supplementation on sleep quality and hormone levels. Our study included 320 patients, and after follow-up, 290 patients completed the trial. We assessed insomnia severity using the Insomnia Severity Index and analyzed changes in melatonin and cortisol levels, which are key sleep hormones.
Our findings indicated that magnesium supplementation—whether alone or in combination with potassium—had a notable positive impact. Participants who received magnesium and potassium demonstrated significant improvements in both insomnia severity and sleep hormone levels. It was exciting to see how these supplements could enhance sleep duration and quality in those facing the dual challenges of insomnia and diabetes.
Although the combination of magnesium and potassium was effective, we recognize that this limits a clear assessment of magnesium's isolated effects. Nevertheless, our research adds valuable insights on how these minerals may play a role in managing insomnia among diabetic patients.
Read More
8
Magnesium may aid post-surgery insomnia
Effect of intra-operative Magnesium sulphate on the occurrence of post-operative delirium and insomnia in patients undergoing lumbar fixation: a randomized controlled trial.
We conducted a study to explore how magnesium affects insomnia in patients undergoing lumbar fixation surgery. Our research involved 80 participants, divided into two groups: one received conventional general anesthesia supplemented with magnesium sulfate, while the other had standard anesthesia without magnesium.
We assessed various factors, including insomnia severity using the Insomnia Severity Index and post-operative delirium through the Memorial Delirium Assessment Scale. Interestingly, our findings indicated a significant relationship between the administration of magnesium and reduced instances of post-operative insomnia.
This suggests that magnesium may be beneficial in easing sleep disturbances experienced by some patients after surgery. However, we also noted variations due to other factors like pain and depression, which could influence the overall results.
While the relationship is promising, it’s essential to recognize that there may be multiple factors at play that contribute to insomnia post-surgery. Overall, our evaluation presents magnesium as a potentially helpful option for enhancing sleep quality in these patients.
Wonderful calcium! I began taking this regularly due to my physician's recommendation. It has no side effects and is well absorbed, which I can tell by the improvement in my nails. After years of dealing with insomnia, I've begun to sleep better and feel calmer, possibly thanks to the magnesium. My husband and son now use it too. I've learnt calcium should be taken daily, making this a regular purchase for our health.
Read More
7.5
Relieves stress
5 people found this helpful
I love magnesium! After using it for a long time, I find it really helps relax my muscles and eases cramps. I've recommended it to my sister and friends, and they swear by it too. Magnesium is vital for the nervous system, reducing anxiety and fatigue and helping with symptoms like insomnia and nervousness. It's crucial for maintaining a balanced mood during stressful times.
Read More
9
Supports insomnia relief
4 people found this helpful
I recommend this! I’ve been taking it for a long time as it helps relax my muscles and alleviate insomnia. Magnesium serves as a natural stress reliever, which is crucial for my well-being.
Read More
9
Enhanced sleep quality
2 people found this helpful
I've dealt with insomnia and read that magnesium and calcium might help. After buying this second bottle, I’ve found my sleep quality has really improved, and I've been able to relieve myself better too. Good sleep has even positively impacted my metabolism!
Read More
9
Insomnia relief
2 people found this helpful
This supplement also serves as a good skin care product! I've struggled with poor sleep quality and decided to try magnesium for my insomnia. I'm happy to report a significant improvement!
Insomnia is a common sleep disorder characterized by the inability to fall asleep, stay asleep, or wake up too early and not be able to go back to sleep. Individuals experiencing insomnia may find that it affects their daytime functioning, leading to issues such as fatigue, mood disturbances, and difficulty concentrating. Insomnia can be classified into two main types: acute insomnia, which lasts for a short period often triggered by stress or life changes, and chronic insomnia, which occurs at least three times a week for three months or longer, and may require more in-depth evaluation and treatment.
Numerous factors can contribute to insomnia, including stress, anxiety, poor sleep habits, medical conditions, and the use of certain medications. Treatment for insomnia typically involves a combination of lifestyle changes, cognitive behavioral therapy for insomnia (CBT-I), and sometimes medication. Establishing a consistent sleep routine, creating a comfortable sleep environment, and practicing relaxation techniques can help improve sleep quality. If insomnia persists, it is advisable to consult a healthcare professional for proper diagnosis and customized treatment options.
Calcium magnesium refers to a dietary supplement that combines two essential minerals, calcium and magnesium, which play critical roles in maintaining various bodily functions. Calcium is vital for building and maintaining strong bones and teeth, while magnesium supports muscle function, energy production, and the regulation of calcium levels in the body. Together, these minerals work synergistically to promote overall health, particularly in areas such as bone density, cardiovascular health, and muscle function.
Supplements that contain both calcium and magnesium can be particularly beneficial for individuals who may be deficient in these minerals due to dietary restrictions or health conditions. They are available in various forms, including tablets, capsules, and powders. When considering a calcium magnesium supplement, it's essential to choose a product with the right ratio of these minerals, as well as other supporting vitamins and minerals like vitamin D, which enhances calcium absorption. Always consult with a healthcare provider before starting any new supplement regimen to ensure it aligns with your health needs and goals.
Calcium and magnesium are essential minerals that play crucial roles in various bodily functions, including muscle and nerve function, and they may have an impact on sleep quality. Some studies suggest that magnesium, in particular, is effective in promoting relaxation and improving sleep patterns. Magnesium helps regulate neurotransmitters that send signals to the brain, which may help in easing anxiety and improving sleep. Similarly, calcium is involved in the body's production of melatonin, the hormone that regulates sleep-wake cycles. Thus, a balanced intake of both minerals might contribute to better sleep.
However, while some users report improvements with supplementation, scientific evidence is mixed, and it is important to approach sleep issues holistically. Factors like sleep hygiene, stress management, and overall lifestyle play significant roles in insomnia. If you are considering calcium and magnesium supplements for insomnia, it is wise to consult with a healthcare provider to determine the appropriate dosage and whether these minerals are right for your specific situation.
Based on user reviews, individuals taking this supplement for insomnia typically report noticing improvements in their sleep quality within a few days to a month. For instance, one user noted a "slight improvement" in sleep quality after a few days of use Read Review. Others mentioned a more gradual improvement, with one user stating that they felt a gradual enhancement after incorporating magnesium into their routine, which ultimately helped stabilize their sleep Read Review.
Additionally, several users have reported significant benefits after consistent use over a few weeks, with longer-term effects resulting in improved restfulness and overall health Read Review. The variability in the reports suggests that individual experiences may depend on factors such as existing sleep issues, lifestyle, and overall health. However, many users seem to feel positive effects from this supplement within the first month of use.
Several studies indicate that magnesium supplementation may assist in alleviating insomnia, particularly in specific populations. For instance, a randomized controlled trial found that magnesium positively impacted both sleep quality and insomnia severity among diabetic patients, which suggests its potential benefits [1]. Similarly, research involving older adults revealed that magnesium supplementation led to significant improvements in sleep efficacy and overall insomnia severity [8]. A meta-analysis also noted that a number of trials showed participants receiving magnesium experienced enhancements in sleep quality compared to those who did not [3].
However, while the general trend leans towards magnesium being beneficial, there are studies with mixed results, and the evidence quality varies. For example, other studies that included magnesium alongside additional supplements do not allow for conclusive evidence regarding magnesium's isolated effects on insomnia [5]. Overall, while magnesium may be a promising supplement for improving sleep quality, especially in specific groups like older adults or those with insomnia linked to underlying health conditions, more targeted and larger studies are necessary to fully establish its effectiveness [4].
Users have reported a variety of improvements in symptoms related to insomnia after incorporating this supplement into their routines. Many reviews highlight a noticeable enhancement in sleep quality, with one user sharing that their insomnia symptoms improved significantly and they now experience better and calmer sleep Read Review. Others, like a user who initially sought help for muscle cramps, noted that the magnesium also alleviated their insomnia, showcasing its multi-functional benefits Read Review. The consistency of these positive outcomes suggests that regular use may enhance overall health and sleep patterns.
While individual experiences differ, common threads among users include reduced anxiety and improved mood, contributing to overall better sleep experiences. For instance, a user shared that their sleep quality improved after taking the supplement for just a few days, indicating that benefits can be observed relatively quickly Read Review. Others have reported long-term improvements, noting stabilization in their sleep quality and reduction in insomnia-related symptoms Read Review. As always, results can vary due to personal health factors, but a significant number of users seem to find relief from their insomnia through this product.
Users have reported that combining this supplement with other supplements can enhance its effectiveness in managing insomnia. For example, one user noted that after initially using the supplement for muscle cramps, they found it also alleviated their insomnia, highlighting its multifaceted benefits Read Review. Another user stated that after incorporating magnesium into their routine, they experienced a significant improvement in sleep quality, suggesting that the combination of magnesium with calcium can stabilize and enhance sleep quality Read Review.
Furthermore, some users have emphasized the importance of balancing magnesium with calcium for optimal effectiveness. One mentioned that the balanced content of these minerals in the supplement helped alleviate insomnia-related issues Read Review. Users also noted improvements in mood and stress relief when combining this supplement with a proper diet and exercise, suggesting that a holistic approach may yield even greater benefits for sleep Read Review. Overall, many individuals seem to find that the synergy between supplements can lead to a notable enhancement in sleep quality and overall well-being.
Based on user reviews, there seems to be a consensus that Calcium and Magnesium supplements can significantly aid in improving sleep quality and alleviating insomnia. Users often noted the calming effects of Magnesium, with one reviewer reporting a marked reduction in insomnia after incorporating it into their routine, indicating a beneficial synergy with Calcium for sleep improvement Read Review. Many users advocated for regular use, mentioning the importance of consistent dosing for optimal results Read Review. Additionally, some users mention taking it before bedtime, noting that even one tablet can be effective in relieving insomnia Read Review.
However, specific dosage recommendations were not frequently detailed in the reviews. Several users emphasized improvements after a month of consistent use, suggesting that a sustained regimen may be beneficial Read Review. Many found it helpful for managing muscle cramps and general relaxation in the evenings, which contributed to better sleep quality Read Review. Overall, while individual experiences may vary, consistent intake of Calcium and Magnesium appears to be widely recognized as an effective approach for managing insomnia.
6
Better sleep
4 people found this helpful
Suffering from insomnia, I tried magnesium tablets recently on advice from others. The pills are a bit large, making them hard to swallow, but I’ve noticed a slight improvement in my sleep quality after taking them for a few days.
7.5
Insomnia improvement
1 people found this helpful
I’ve suffered from long-term insomnia and started taking this calcium supplement after my doctor’s recommendation. I felt a gradual improvement in my sleep quality and later added magnesium to my routine, which further stabilised my sleep.
9
Supports insomnia relief
4 people found this helpful
I recommend this! I’ve been taking it for a long time as it helps relax my muscles and alleviate insomnia. Magnesium serves as a natural stress reliever, which is crucial for my well-being.
9
Improved sleep quality
7 people found this helpful
Wonderful calcium! I began taking this regularly due to my physician's recommendation. It has no side effects and is well absorbed, which I can tell by the improvement in my nails. After years of dealing with insomnia, I've begun to sleep better and feel calmer, possibly thanks to the magnesium. My husband and son now use it too. I've learnt calcium should be taken daily, making this a regular purchase for our health.
9
Calmer nights
1 people found this helpful
This supplement has dramatically improved my insomnia. I initially took it for better nail growth but found that my sleep quality is now normalised. My headaches have decreased, and I feel calmer overall.
9
Strengthened sleep quality
The calcium and magnesium in this complex are optimally balanced. They help strengthen bones and alleviate insomnia-related issues like muscle cramps. I've experienced fatigue and general weakness due to a calcium deficiency, which has affected my sleep. I've taken this for a month in spring and autumn with noticeable improvement, especially regarding my knee and back pain.
7.5
Lowered blood pressure
2 people found this helpful
At 33, with 39% body fat and high blood pressure, I found myself battling insomnia alongside my temper issues. After using magnesium and potassium iodine from IHERB, my blood pressure has dropped significantly, and my insomnia has improved. I combine this with low-intensity exercise and a proper diet.
9
Calms insomnia
1 people found this helpful
It’s rich in content. Even taking one tablet before bedtime can help with calcium and magnesium levels to relieve insomnia and constipation. I highly recommend it to others in need.
8
Magnesium improves insomnia in diabetes
Effects of magnesium and potassium supplementation on insomnia and sleep hormones in patients with diabetes mellitus.
We conducted a randomized controlled trial focusing on individuals with diabetes who struggle with insomnia. Over two months, we examined the effects of magnesium and potassium supplementation on sleep quality and hormone levels. Our study included 320 patients, and after follow-up, 290 patients completed the trial. We assessed insomnia severity using the Insomnia Severity Index and analyzed changes in melatonin and cortisol levels, which are key sleep hormones.
Our findings indicated that magnesium supplementation—whether alone or in combination with potassium—had a notable positive impact. Participants who received magnesium and potassium demonstrated significant improvements in both insomnia severity and sleep hormone levels. It was exciting to see how these supplements could enhance sleep duration and quality in those facing the dual challenges of insomnia and diabetes.
Although the combination of magnesium and potassium was effective, we recognize that this limits a clear assessment of magnesium's isolated effects. Nevertheless, our research adds valuable insights on how these minerals may play a role in managing insomnia among diabetic patients.
9
Magnesium improves elderly insomnia
The effect of magnesium supplementation on primary insomnia in elderly: A double-blind placebo-controlled clinical trial.
We conducted a double-blind, placebo-controlled clinical trial to investigate the effects of magnesium supplementation on insomnia in elderly individuals. Our study involved 46 participants who were assigned either to receive 500 mg of magnesium daily or a placebo for a duration of 8 weeks.
Throughout the study, we employed various questionnaires, including the Insomnia Severity Index (ISI), to evaluate the participants' sleep quality both before and after the treatment period. We also monitored the intake of other nutrients and performed blood tests to assess hormone levels related to sleep.
The results showed that magnesium supplementation led to significant improvements in areas such as sleep efficiency, sleep onset timing, and overall insomnia severity. We observed increases in serum levels of melatonin and changes in cortisol and renin levels, indicating a physiological response that could enhance sleep quality.
Overall, it seems that supplementing with magnesium has the potential to improve sleep for older adults struggling with insomnia. This finding could pave the way for new, accessible treatment options for those affected by sleep disorders.
7
Magnesium may improve insomnia
Examining the Effects of Supplemental Magnesium on Self-Reported Anxiety and Sleep Quality: A Systematic Review.
We examined the potential benefits of magnesium supplements for improving sleep quality through a detailed analysis of existing clinical studies. Our systematic review focused specifically on trials investigating how magnesium affects insomnia, which have gained popularity among people seeking natural remedies for sleep problems.
A total of 15 relevant studies were reviewed. Among these, eight studies looked specifically at sleep-related outcomes, often employing the Pittsburgh Sleep Quality Index (PSQI) to measure improvements. The results were promising—five out of the eight studies indicated that magnesium supplementation led to better sleep quality.
However, it's important to note that not all studies observed benefits; two showed no significant improvements, and one provided mixed results. Many of these studies varied in the dosage, type of magnesium used, and overall participant numbers, which made it challenging to draw firm conclusions. Still, the general trend suggests that magnesium could indeed be helpful, especially for those who start with low magnesium levels.
Ultimately, while the findings lean towards positive, further large-scale, randomized trials are necessary to confirm the effectiveness of specific magnesium formulations and dosages in treating insomnia. We take these outcomes seriously, considering them a first step towards understanding how this mineral can help those struggling with sleep issues.
9
Magnesium shows potential insomnia benefits
The Effects of Magnesium - Melatonin - Vit B Complex Supplementation in Treatment of Insomnia.
We explored the potential benefits of a supplement containing magnesium, melatonin, and vitamin B complex in treating insomnia. The study involved 60 patients diagnosed with insomnia, who were divided into a study group and a control group. Over three months, the study group received a daily dose of the supplement, while the control group did not receive it.
At the start, both groups had similar levels of insomnia, indicated by their scores on the Athens insomnia scale. However, after three months of supplementation, the study group showed a significant improvement, with their insomnia scores decreasing, indicating mild insomnia. In contrast, the control group’s scores remained stable, suggesting they continued to experience moderate insomnia.
Although magnesium was part of the supplement, the study design makes it challenging to isolate its specific effects on insomnia. Nevertheless, we observed that combining magnesium with melatonin and vitamin B complex potentially enhances sleep quality for those struggling with insomnia.
4
Magnesium shows limited sleep benefits
Oral magnesium supplementation for insomnia in older adults: a Systematic Review & Meta-Analysis.
We explored the effects of magnesium supplementation on insomnia in older adults through a systematic review and meta-analysis. Our investigation included several studies that compared magnesium with a placebo or no treatment.
We found three randomized control trials involving 151 older adults across three countries. The pooled results indicated that individuals taking magnesium had a notable decrease in sleep onset latency, averaging a reduction of 17.36 minutes compared to those on placebo. However, the improvement in total sleep time, which increased by 16.06 minutes in the magnesium group, did not reach statistical significance.
Despite these findings, we must emphasize that the overall quality of the research is below standards necessary for making firm recommendations. All studies reviewed showed a moderate to high risk of bias, and the evidence quality ranged from low to very low. Nonetheless, magnesium is an affordable and widely accessible option for those struggling with insomnia symptoms, suggesting it may be a reasonable consideration for some older adults.
References
Khalid S, Bashir S, Mehboob R, Anwar T, Ali M, et al. Effects of magnesium and potassium supplementation on insomnia and sleep hormones in patients with diabetes mellitus. Front Endocrinol (Lausanne). 2024;15:1370733. doi:10.3389/fendo.2024.1370733
Fathy W, Hussein M, Elanwar R, Elmoutaz H, Abdelsadek DA, et al. Effect of intra-operative Magnesium sulphate on the occurrence of post-operative delirium and insomnia in patients undergoing lumbar fixation: a randomized controlled trial. BMC Anesthesiol. 2024;24:289. doi:10.1186/s12871-024-02579-6
Rawji A, Peltier MR, Mourtzanakis K, Awan S, Rana J, et al. Examining the Effects of Supplemental Magnesium on Self-Reported Anxiety and Sleep Quality: A Systematic Review. Cureus. 2024;16:e59317. doi:10.7759/cureus.59317
Mah J, Pitre T. Oral magnesium supplementation for insomnia in older adults: a Systematic Review & Meta-Analysis. BMC Complement Med Ther. 2021;21:125. doi:10.1186/s12906-021-03297-z
Djokic G, Vojvodić P, Korcok D, Agic A, Rankovic A, et al. The Effects of Magnesium - Melatonin - Vit B Complex Supplementation in Treatment of Insomnia. Open Access Maced J Med Sci. 2019;7:3101. doi:10.3889/oamjms.2019.771
Cao Y, Zhen S, Taylor AW, Appleton S, Atlantis E, et al. Magnesium Intake and Sleep Disorder Symptoms: Findings from the Jiangsu Nutrition Study of Chinese Adults at Five-Year Follow-Up. Nutrients. 2018;10. doi:10.3390/nu10101354
Scholey A, Benson S, Gibbs A, Perry N, Sarris J, et al. Exploring the Effect of Lactium™ and Zizyphus Complex on Sleep Quality: A Double-Blind, Randomized Placebo-Controlled Trial. Nutrients. 2017;9. doi:10.3390/nu9020154
Abbasi B, Kimiagar M, Sadeghniiat K, Shirazi MM, Hedayati M, et al. The effect of magnesium supplementation on primary insomnia in elderly: A double-blind placebo-controlled clinical trial. J Res Med Sci. 2012;17:1161.
Rondanelli M, Opizzi A, Monteferrario F, Antoniello N, Manni R, et al. The effect of melatonin, magnesium, and zinc on primary insomnia in long-term care facility residents in Italy: a double-blind, placebo-controlled clinical trial. J Am Geriatr Soc. 2011;59:82. doi:10.1111/j.1532-5415.2010.03232.x
Mucci M, Carraro C, Mancino P, Monti M, Papadia LS, et al. Soy isoflavones, lactobacilli, Magnolia bark extract, vitamin D3 and calcium. Controlled clinical study in menopause. Minerva Ginecol. 2006;58:323.
Hornyak M, Haas P, Veit J, Gann H, Riemann D. Magnesium treatment of primary alcohol-dependent patients during subacute withdrawal: an open pilot study with polysomnography. Alcohol Clin Exp Res. 2004;28:1702.
Hornyak M, Voderholzer U, Hohagen F, Berger M, Riemann D. Magnesium therapy for periodic leg movements-related insomnia and restless legs syndrome: an open pilot study. Sleep. 1998;21:501.