Overview

SCIENTIFIC SCORE
Moderately Effective
Based on 12 Researches
8
USERS' SCORE
Good
Based on 8 Reviews
8.6
Supplement Facts
Serving Size: 1 Level Teaspoon (approx. 4 g)
Amount Per Serving
%DV
Calories
10 
 
Total Carbohydrate
4 g
1%**
Dietary Fiber
4 g
14%*
Organic Inulin (FOS) (from Blue Agave)
3.3 g
†

Top Medical Research Studies

9
We explored the potential of an inulin gel designed to improve oral immunotherapy for food allergies. The research investigated how this gel, formulated with allergens, positively influenced gut microbiota in allergic mice.

Our findings revealed that the inulin gel not only helped normalize harmful gut bacteria but also established a specific tolerance to allergens. This means that the mice showed lasting unresponsiveness to food that previously triggered their allergies.

The success of this treatment was linked to increased allergen absorption and a decrease in harmful immune responses, making it a promising option for future food allergy therapies. Moreover, we noted a restoration of beneficial bacterial populations in the gut, pointing to a comprehensive approach to allergy treatment that also considers the microbiome.

Overall, this study emphasizes the potential of using engineered inulin gel as a way to modulate gut bacteria while effectively treating food allergies and possibly other allergic conditions.
9
Inulin may reduce food allergies
We investigated whether supplementing pregnant mice with inulin and galacto-oligosaccharides could help their offspring avoid developing food allergies, specifically wheat allergy. Through this study, we found that such prebiotic supplementation during gestation resulted in beneficial changes in the mother’s gut microbiota, which were passed down to the offspring.

The adjusted microbiota in the mothers fostered an increase in protective immune cell types in their young, leading to a more tolerant immune system in the offspring. This supportive environment contributed to reducing the severity of allergy symptoms related to wheat.

Our findings suggest that introducing prebiotics like inulin during pregnancy can create a healthier gut balance and potentially shield children from developing certain food allergies as they grow.
8
Inulin offers allergy protection
We explored how inulin, a natural fiber, might help in managing food allergies by looking at changes in intestinal health and gut bacteria. In our study, we created a mouse model of food allergies by sensitizing them with ovalbumin (OVA), a common allergen. The mice were then divided into groups, receiving either water, high-dose inulin, or low-dose inulin before exposure to OVA.

After subjecting the mice to the allergen, we monitored allergic reactions and took note of several bodily responses. We found that inulin didn't seem to change the mice's weight. However, it did reduce allergic reactions and inflammation in the intestines. Notably, levels of immunoglobulin E (IgE), which is linked to allergic responses, were lower in mice treated with inulin compared to those that weren't treated. Additionally, IgA levels, an important factor for gut health, were higher in the mucus of inulin-treated mice, indicating improved intestinal defense.

To gain insights into how inulin impacted gut bacteria, we analyzed the mice's fecal samples. We discovered that inulin treatment altered the composition of gut bacteria, decreasing certain groups known to be associated with allergic reactions while increasing beneficial strains. This shift may play a role in reducing allergy symptoms and promoting a healthier gut environment.

Overall, our findings suggest that inulin can effectively protect against food allergies, partially by reshaping the gut microbiome. This exciting research points to inulin as a promising dietary intervention for managing food allergies.

Most Useful Reviews

9
Boosts microflora
88 people found this helpful
Good for your health! After drinking inulin for over a month with probiotics, I feel lighter, and my allergies have disappeared. My skin shines, and everything functions well, especially after antibiotics. I mix one measuring spoon in a glass of room temperature water; one is enough for me, but everyone varies, so listen to your body. The sweet, pleasant taste makes it enjoyable. I will take it on a course basis and am pleased with my purchase. Wishing good health to all!
9
Effective for pets
49 people found this helpful
Helped wonders for my dog! My three-year-old pit bull had severe allergies and skin infections. After trying all kinds of treatments, I added this Inulin powder with probiotics to her diet. It's a lifesaver! No more itching or infections.
9
Child's chair improved
2 people found this helpful
Great product! I give it to my child, and it has improved their bowel movements. There are no allergies or side effects reported. I plan to continue using it indefinitely.

Medical Researches

SCIENTIFIC SCORE
Moderately Effective
Based on 12 Researches
8
  • All Researches
9
We explored the potential of an inulin gel designed to improve oral immunotherapy for food allergies. The research investigated how this gel, formulated with allergens, positively influenced gut microbiota in allergic mice.

Our findings revealed that the inulin gel not only helped normalize harmful gut bacteria but also established a specific tolerance to allergens. This means that the mice showed lasting unresponsiveness to food that previously triggered their allergies.

The success of this treatment was linked to increased allergen absorption and a decrease in harmful immune responses, making it a promising option for future food allergy therapies. Moreover, we noted a restoration of beneficial bacterial populations in the gut, pointing to a comprehensive approach to allergy treatment that also considers the microbiome.

Overall, this study emphasizes the potential of using engineered inulin gel as a way to modulate gut bacteria while effectively treating food allergies and possibly other allergic conditions.
9
Fructans show promise for allergy prevention
We set out to explore the impact of inulin, along with a short fructan called 1-kestose (Kes), on food allergies. To do this, we used a mouse model that mimicked allergic reactions triggered by ovalbumin (OVA), a common allergen. The goal was to see if combining these two types of fructans could provide enhanced protective effects against allergies.

Our findings were promising. The combination of Kes and inulin showed a greater ability to reduce allergy symptoms compared to when each was taken alone. We observed improvement in various measures related to allergic reactions, including reduced total IgA levels and less OVA-specific IgE. Notably, the combination also helped balance the levels of important immune proteins, like increasing the anti-inflammatory cytokine IL-10, which is vital for managing allergic responses.

Further analysis revealed that taking these fructans together not only improved symptoms but also influenced the gut microbiota in a beneficial way. Certain beneficial bacteria that were reduced during allergy sensitization were restored following fructan intake. This suggests that the combination may help train the gut flora to resist allergic reactions better instead of merely restoring a previous state.

While our study indicates active mechanisms at play with combined intake, it should be noted that isolating the effects of inulin on allergies alone remains difficult based on our current results. Overall, the findings suggest that combining short and long fructans may offer a helpful strategy in reducing the risk of food allergies.
9
Inulin may reduce food allergies
We investigated whether supplementing pregnant mice with inulin and galacto-oligosaccharides could help their offspring avoid developing food allergies, specifically wheat allergy. Through this study, we found that such prebiotic supplementation during gestation resulted in beneficial changes in the mother’s gut microbiota, which were passed down to the offspring.

The adjusted microbiota in the mothers fostered an increase in protective immune cell types in their young, leading to a more tolerant immune system in the offspring. This supportive environment contributed to reducing the severity of allergy symptoms related to wheat.

Our findings suggest that introducing prebiotics like inulin during pregnancy can create a healthier gut balance and potentially shield children from developing certain food allergies as they grow.
9
Cow's milk allergy treatment explored
We examined the effectiveness of an amino acid formula that includes prebiotics like inulin and probiotics in infants suffering from cow's milk protein allergy (CMPA). This study, which analyzed data from 148 infants, aimed to see if using this synbiotic formula (AAF-Syn) could improve clinical outcomes compared to a standard amino acid formula without synbiotics.

Our findings revealed that infants on the AAF-Syn formula experienced fewer symptoms, infections, and medication prescriptions. Specifically, there was a significant reduction in symptoms by 37% and a decrease in infections by 35%. Moreover, babies using the synbiotic formula had a better chance of managing their symptoms without needing more hypoallergenic formulas.

Interestingly, those on AAF-Syn could reach a state of being symptom-free sooner, usually around 1.35 years, compared to 1.95 years for those on the standard formula. Additionally, there seemed to be potential cost savings associated with AAF-Syn, amounting to about ÂŁ452 per infant over the course of treatment.

Although the study highlights the benefits of the entire synbiotic formulation, it didn't isolate inulin’s specific effects on allergies. This means we can see positive trends with the whole formula, but we cannot definitively say how much inulin alone contributes to these benefits. Further research could help clarify this connection, especially since the benefits observed align with previous clinical trials.
Our exploration focused on the potential of Advax adjuvant in enhancing Jack Jumper ant venom immunotherapy, aiming to improve outcomes for allergy sufferers with limited venom supplies. This study assessed the stability and immune response generated by low-dose Jack Jumper ant venom (JJAV) when combined with the Advax polysaccharide adjuvant.

We found that the JJAV mixed with Advax maintained its integrity and effectiveness over time, showing promising results in laboratory conditions. Remarkably, mice that received the low-dose JJAV with Advax had higher levels of specific antibodies compared to those who received a much larger dose of JJAV alone.

This suggests that Advax could potentially reduce the amount of venom needed for effective treatment, which is a significant development given the challenges associated with harvesting venom from wild ants. As we move forward, this study sets the stage for a future clinical trial to further test the benefits of Advax in human patients suffering from Jack Jumper ant allergies.

User Reviews

USERS' SCORE
Good
Based on 8 Reviews
8.6
  • All Reviews
  • Positive Reviews
  • Negative Reviews
9
Boosts microflora
88 people found this helpful
Good for your health! After drinking inulin for over a month with probiotics, I feel lighter, and my allergies have disappeared. My skin shines, and everything functions well, especially after antibiotics. I mix one measuring spoon in a glass of room temperature water; one is enough for me, but everyone varies, so listen to your body. The sweet, pleasant taste makes it enjoyable. I will take it on a course basis and am pleased with my purchase. Wishing good health to all!
9
Effective for pets
49 people found this helpful
Helped wonders for my dog! My three-year-old pit bull had severe allergies and skin infections. After trying all kinds of treatments, I added this Inulin powder with probiotics to her diet. It's a lifesaver! No more itching or infections.
9
Child's chair improved
2 people found this helpful
Great product! I give it to my child, and it has improved their bowel movements. There are no allergies or side effects reported. I plan to continue using it indefinitely.
9
Helps clear allergies
1 people found this helpful
This helps with allergies! It contains clean ingredients too. We've just discovered its benefits based on our doctor's recommendation.
10
Brightens skin
For developing beneficial microflora, I’ve been giving my child inulin for over a month along with probiotics. It’s taken during the day, while the probiotic is for bedtime. The allergies are gone, my child's skin is radiant, and everything runs smoothly. I dilute half a measuring spoon in a glass of water; it’s sweet and pleasant. There's no resistance to inulin; I’m satisfied with the purchase. Wishing everyone good health!

Frequently Asked Questions

9
Boosts microflora
88 people found this helpful
Good for your health! After drinking inulin for over a month with probiotics, I feel lighter, and my allergies have disappeared. My skin shines, and everything functions well, especially after antibiotics. I mix one measuring spoon in a glass of room temperature water; one is enough for me, but everyone varies, so listen to your body. The sweet, pleasant taste makes it enjoyable. I will take it on a course basis and am pleased with my purchase. Wishing good health to all!
10
Brightens skin
For developing beneficial microflora, I’ve been giving my child inulin for over a month along with probiotics. It’s taken during the day, while the probiotic is for bedtime. The allergies are gone, my child's skin is radiant, and everything runs smoothly. I dilute half a measuring spoon in a glass of water; it’s sweet and pleasant. There's no resistance to inulin; I’m satisfied with the purchase. Wishing everyone good health!
8
Effective against fungus
1 people found this helpful
Good! I started taking inulin based on my doctor’s advice to eliminate fungus from sunspots. Initially, it caused flatulence, but I began dissolving it in water, helping clear the gas. The fungus has decreased, and my allergies have passed (particularly those to milk). This effective remedy is reasonably priced!
9
Helps clear allergies
1 people found this helpful
This helps with allergies! It contains clean ingredients too. We've just discovered its benefits based on our doctor's recommendation.
2
Limited effects
1 people found this helpful
The effect is average; the taste differs from my usual probiotics, and my gastrointestinal allergies have not improved, so I will not purchase it again.
8
Inulin offers allergy protection
We explored how inulin, a natural fiber, might help in managing food allergies by looking at changes in intestinal health and gut bacteria. In our study, we created a mouse model of food allergies by sensitizing them with ovalbumin (OVA), a common allergen. The mice were then divided into groups, receiving either water, high-dose inulin, or low-dose inulin before exposure to OVA.

After subjecting the mice to the allergen, we monitored allergic reactions and took note of several bodily responses. We found that inulin didn't seem to change the mice's weight. However, it did reduce allergic reactions and inflammation in the intestines. Notably, levels of immunoglobulin E (IgE), which is linked to allergic responses, were lower in mice treated with inulin compared to those that weren't treated. Additionally, IgA levels, an important factor for gut health, were higher in the mucus of inulin-treated mice, indicating improved intestinal defense.

To gain insights into how inulin impacted gut bacteria, we analyzed the mice's fecal samples. We discovered that inulin treatment altered the composition of gut bacteria, decreasing certain groups known to be associated with allergic reactions while increasing beneficial strains. This shift may play a role in reducing allergy symptoms and promoting a healthier gut environment.

Overall, our findings suggest that inulin can effectively protect against food allergies, partially by reshaping the gut microbiome. This exciting research points to inulin as a promising dietary intervention for managing food allergies.
7
Inulin shows promise for allergy relief
We explored how a combination of prebiotics, including inulin, affects allergy symptoms in a mouse model of atopic dermatitis (AD). The study involved treating 1-chloro-2,4-dinitrobenzene (DNCB)-exposed NC/Nga mice with inulin as well as other prebiotics and assessing the results.

Mice were divided into several groups: some received no treatment, others were given Zyrtec (a known allergy remedy), and the remaining groups received different prebiotics, including inulin. Notably, those receiving the prebiotic treatments showed a reduction in allergy symptoms and a positive shift in immune responses.

Specifically, we observed that inulin—and the other prebiotics—helped balance immune responses, resulting in less severe skin lesions linked to allergies. Furthermore, the prebiotics appeared to influence beneficial gut bacteria, which might play a role in alleviating allergy symptoms.

Although it’s challenging to isolate the effects of inulin alone since it was used in conjunction with other prebiotics, our findings suggest that it may still be beneficial for managing allergic reactions, particularly in the context of atopic dermatitis.
4
We explored how different doses of inulin, a common dietary supplement known for supporting gut health, influence food allergies in a BALB/c mouse model. Our focus was on understanding how inulin affects allergies, particularly food allergies induced by ovalbumin (OVA).

Upon investigation, we found that a moderate dose of 50 mg of inulin resulted in the best therapeutic outcomes, effectively alleviating allergy symptoms. However, when we increased the dosage to 80 mg, it led to severe allergic reactions and signs of intestinal inflammation. This high level of inulin intake contributed to various negative changes, such as an imbalance in gut bacteria, compromised gut barrier function, and an excess of short-chain fatty acids (SCFAs), which are linked to immune system issues.

By analyzing the bacterial profiles in the mice, we noticed that certain bacteria, like Ruminococcaceae and Bifidobacterium, increased due to the high inulin levels. Unfortunately, these bacteria were connected to worsening allergy symptoms rather than improving gut health.

Overall, our findings highlight that while inulin can be beneficial in moderate amounts, high doses may exacerbate allergies, stressing the importance of personalized approaches when using inulin supplements.
9
Cow's milk allergy treatment explored
We examined the effectiveness of an amino acid formula that includes prebiotics like inulin and probiotics in infants suffering from cow's milk protein allergy (CMPA). This study, which analyzed data from 148 infants, aimed to see if using this synbiotic formula (AAF-Syn) could improve clinical outcomes compared to a standard amino acid formula without synbiotics.

Our findings revealed that infants on the AAF-Syn formula experienced fewer symptoms, infections, and medication prescriptions. Specifically, there was a significant reduction in symptoms by 37% and a decrease in infections by 35%. Moreover, babies using the synbiotic formula had a better chance of managing their symptoms without needing more hypoallergenic formulas.

Interestingly, those on AAF-Syn could reach a state of being symptom-free sooner, usually around 1.35 years, compared to 1.95 years for those on the standard formula. Additionally, there seemed to be potential cost savings associated with AAF-Syn, amounting to about ÂŁ452 per infant over the course of treatment.

Although the study highlights the benefits of the entire synbiotic formulation, it didn't isolate inulin’s specific effects on allergies. This means we can see positive trends with the whole formula, but we cannot definitively say how much inulin alone contributes to these benefits. Further research could help clarify this connection, especially since the benefits observed align with previous clinical trials.

References

  1. Guo X, Luo Y, Fan X, Simpson BK, Li W, et al. Effects of Polysaccharide Supplementation on Lactic Acid Bacteria-Fermented Soy Protein Gel: Structural Characteristics, Allergenicity, and Epitope Analysis. Foods. 2025;14. 10.3390/foods14040701
  2. Han K, Xie F, Animasahun O, Nenwani M, Kitamoto S, et al. Inulin-gel-based oral immunotherapy remodels the small intestinal microbiome and suppresses food allergy. Nat Mater. 2024;23:1444. 10.1038/s41563-024-01909-w
  3. Zhu Z, Hu C, Liu Y, Wang F, Zhu B. Inulin has a beneficial effect by modulating the intestinal microbiome in a BALB/c mouse model. Benef Microbes. 2023;14:371. 10.1163/18762891-20220094
  4. Takahashi H, Fujii T, Yamakawa S, Yamada C, Fujiki K, et al. Combined oral intake of short and long fructans alters the gut microbiota in food allergy model mice and contributes to food allergy prevention. BMC Microbiol. 2023;23:266. 10.1186/s12866-023-03021-6
  5. Kang M, Jung JH, Kim JY, Hong SH, Her Y. Therapeutic and Preventive Effect of Orally Administered Prebiotics on Atopic Dermatitis in a Mouse Model. Allergy Asthma Immunol Res. 2023;15:303. 10.4168/aair.2023.15.3.303
  6. Xie Q, Mu K, Chen C, Gu S, Luo D, et al. The high dose of inulin exacerbated food allergy through the excess accumulation of short-chain fatty acids in a BABL/c mouse model. Int J Biol Macromol. 2023;230:123234. 10.1016/j.ijbiomac.2023.123234
  7. Selle A, Brosseau C, Dijk W, Duval A, Bouchaud G, et al. Prebiotic Supplementation During Gestation Induces a Tolerogenic Environment and a Protective Microbiota in Offspring Mitigating Food Allergy. Front Immunol. 2021;12:745535. 10.3389/fimmu.2021.745535
  8. Sorensen K, Cawood AL, Cooke LH, Acosta-Mena D, Stratton RJ. The Use of an Amino Acid Formula Containing Synbiotics in Infants with Cow's Milk Protein Allergy-Effect on Clinical Outcomes. Nutrients. 2021;13. 10.3390/nu13072205
  9. Kim JA, Kim SH, Kim IS, Yu DY, Kim GI, et al. Galectin-9 Induced by Dietary Prebiotics Regulates Immunomodulation to Reduce Atopic Dermatitis Symptoms in 1-Chloro-2,4-Dinitrobenzene (DNCB)-Treated NC/Nga Mice. J Microbiol Biotechnol. 2020;30:1343. 10.4014/jmb.2005.05017
  10. Wanandy T, Honda-Okubo Y, Davies NW, Rose HE, Heddle RJ, et al. Pharmaceutical and preclinical evaluation of Advax adjuvant as a dose-sparing strategy for ant venom immunotherapy. J Pharm Biomed Anal. 2019;172:1. 10.1016/j.jpba.2019.04.017
  11. Bouchaud G, Castan L, Chesné J, Braza F, Aubert P, et al. Maternal exposure to GOS/inulin mixture prevents food allergies and promotes tolerance in offspring in mice. Allergy. 2016;71:68. 10.1111/all.12777
  12. Burks AW, Harthoorn LF, Van Ampting MT, Oude Nijhuis MM, Langford JE, et al. Synbiotics-supplemented amino acid-based formula supports adequate growth in cow's milk allergic infants. Pediatr Allergy Immunol. 2015;26:316. 10.1111/pai.12390
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