' 
SCIENTIFIC SCORE
Moderately Effective
Based on 12 Researches
8
USERS' SCORE
Good
Based on 1 Review
8.6
Supplement Facts
Serving Size: 1 Level Teaspoon (approx. 4 g)
Amount Per Serving
%DV
Calories
10
Total Carbohydrate
4 g
1%**
Dietary Fiber
4 g
14%*
Organic Inulin (FOS) (from Blue Agave)
3.3 g
†
Top Medical Research Studies
9
Inulin gel shows promise for allergies
Inulin-gel-based oral immunotherapy remodels the small intestinal microbiome and suppresses food allergy.
High relevance to allergy treatment
We explored the potential of an inulin gel designed to improve oral immunotherapy for food allergies. The research investigated how this gel, formulated with allergens, positively influenced gut microbiota in allergic mice.
Our findings revealed that the inulin gel not only helped normalize harmful gut bacteria but also established a specific tolerance to allergens. This means that the mice showed lasting unresponsiveness to food that previously triggered their allergies.
The success of this treatment was linked to increased allergen absorption and a decrease in harmful immune responses, making it a promising option for future food allergy therapies. Moreover, we noted a restoration of beneficial bacterial populations in the gut, pointing to a comprehensive approach to allergy treatment that also considers the microbiome.
Overall, this study emphasizes the potential of using engineered inulin gel as a way to modulate gut bacteria while effectively treating food allergies and possibly other allergic conditions.
Our findings revealed that the inulin gel not only helped normalize harmful gut bacteria but also established a specific tolerance to allergens. This means that the mice showed lasting unresponsiveness to food that previously triggered their allergies.
The success of this treatment was linked to increased allergen absorption and a decrease in harmful immune responses, making it a promising option for future food allergy therapies. Moreover, we noted a restoration of beneficial bacterial populations in the gut, pointing to a comprehensive approach to allergy treatment that also considers the microbiome.
Overall, this study emphasizes the potential of using engineered inulin gel as a way to modulate gut bacteria while effectively treating food allergies and possibly other allergic conditions.
Read More
9
Inulin may reduce food allergies
Prebiotic Supplementation During Gestation Induces a Tolerogenic Environment and a Protective Microbiota in Offspring Mitigating Food Allergy.
Strong relevance to allergy treatment.
We investigated whether supplementing pregnant mice with inulin and galacto-oligosaccharides could help their offspring avoid developing food allergies, specifically wheat allergy. Through this study, we found that such prebiotic supplementation during gestation resulted in beneficial changes in the mother’s gut microbiota, which were passed down to the offspring.
The adjusted microbiota in the mothers fostered an increase in protective immune cell types in their young, leading to a more tolerant immune system in the offspring. This supportive environment contributed to reducing the severity of allergy symptoms related to wheat.
Our findings suggest that introducing prebiotics like inulin during pregnancy can create a healthier gut balance and potentially shield children from developing certain food allergies as they grow.
The adjusted microbiota in the mothers fostered an increase in protective immune cell types in their young, leading to a more tolerant immune system in the offspring. This supportive environment contributed to reducing the severity of allergy symptoms related to wheat.
Our findings suggest that introducing prebiotics like inulin during pregnancy can create a healthier gut balance and potentially shield children from developing certain food allergies as they grow.
Read More
8
Inulin offers allergy protection
Inulin has a beneficial effect by modulating the intestinal microbiome in a BALB/c mouse model.
Directly addresses inulin's effects.
We explored how inulin, a natural fiber, might help in managing food allergies by looking at changes in intestinal health and gut bacteria. In our study, we created a mouse model of food allergies by sensitizing them with ovalbumin (OVA), a common allergen. The mice were then divided into groups, receiving either water, high-dose inulin, or low-dose inulin before exposure to OVA.
After subjecting the mice to the allergen, we monitored allergic reactions and took note of several bodily responses. We found that inulin didn't seem to change the mice's weight. However, it did reduce allergic reactions and inflammation in the intestines. Notably, levels of immunoglobulin E (IgE), which is linked to allergic responses, were lower in mice treated with inulin compared to those that weren't treated. Additionally, IgA levels, an important factor for gut health, were higher in the mucus of inulin-treated mice, indicating improved intestinal defense.
To gain insights into how inulin impacted gut bacteria, we analyzed the mice's fecal samples. We discovered that inulin treatment altered the composition of gut bacteria, decreasing certain groups known to be associated with allergic reactions while increasing beneficial strains. This shift may play a role in reducing allergy symptoms and promoting a healthier gut environment.
Overall, our findings suggest that inulin can effectively protect against food allergies, partially by reshaping the gut microbiome. This exciting research points to inulin as a promising dietary intervention for managing food allergies.
After subjecting the mice to the allergen, we monitored allergic reactions and took note of several bodily responses. We found that inulin didn't seem to change the mice's weight. However, it did reduce allergic reactions and inflammation in the intestines. Notably, levels of immunoglobulin E (IgE), which is linked to allergic responses, were lower in mice treated with inulin compared to those that weren't treated. Additionally, IgA levels, an important factor for gut health, were higher in the mucus of inulin-treated mice, indicating improved intestinal defense.
To gain insights into how inulin impacted gut bacteria, we analyzed the mice's fecal samples. We discovered that inulin treatment altered the composition of gut bacteria, decreasing certain groups known to be associated with allergic reactions while increasing beneficial strains. This shift may play a role in reducing allergy symptoms and promoting a healthier gut environment.
Overall, our findings suggest that inulin can effectively protect against food allergies, partially by reshaping the gut microbiome. This exciting research points to inulin as a promising dietary intervention for managing food allergies.
Read More
Most Useful Reviews
9.5
Effective for pets
Helped wonders for my dog! My three-year-old pit bull had severe allergies and skin infections. After trying all kinds of treatments, I added this Inulin powder with probiotics to her diet. It's a lifesaver! No more itching or infections.
Read More
Medical Researches
SCIENTIFIC SCORE
Moderately Effective
Based on 12 Researches
8
9
Inulin gel shows promise for allergies
Inulin-gel-based oral immunotherapy remodels the small intestinal microbiome and suppresses food allergy.
High relevance to allergy treatment
We explored the potential of an inulin gel designed to improve oral immunotherapy for food allergies. The research investigated how this gel, formulated with allergens, positively influenced gut microbiota in allergic mice.
Our findings revealed that the inulin gel not only helped normalize harmful gut bacteria but also established a specific tolerance to allergens. This means that the mice showed lasting unresponsiveness to food that previously triggered their allergies.
The success of this treatment was linked to increased allergen absorption and a decrease in harmful immune responses, making it a promising option for future food allergy therapies. Moreover, we noted a restoration of beneficial bacterial populations in the gut, pointing to a comprehensive approach to allergy treatment that also considers the microbiome.
Overall, this study emphasizes the potential of using engineered inulin gel as a way to modulate gut bacteria while effectively treating food allergies and possibly other allergic conditions.
Our findings revealed that the inulin gel not only helped normalize harmful gut bacteria but also established a specific tolerance to allergens. This means that the mice showed lasting unresponsiveness to food that previously triggered their allergies.
The success of this treatment was linked to increased allergen absorption and a decrease in harmful immune responses, making it a promising option for future food allergy therapies. Moreover, we noted a restoration of beneficial bacterial populations in the gut, pointing to a comprehensive approach to allergy treatment that also considers the microbiome.
Overall, this study emphasizes the potential of using engineered inulin gel as a way to modulate gut bacteria while effectively treating food allergies and possibly other allergic conditions.
Read More
9
Fructans show promise for allergy prevention
Combined oral intake of short and long fructans alters the gut microbiota in food allergy model mice and contributes to food allergy prevention.
Limited isolated effect of inulin.
We set out to explore the impact of inulin, along with a short fructan called 1-kestose (Kes), on food allergies. To do this, we used a mouse model that mimicked allergic reactions triggered by ovalbumin (OVA), a common allergen. The goal was to see if combining these two types of fructans could provide enhanced protective effects against allergies.
Our findings were promising. The combination of Kes and inulin showed a greater ability to reduce allergy symptoms compared to when each was taken alone. We observed improvement in various measures related to allergic reactions, including reduced total IgA levels and less OVA-specific IgE. Notably, the combination also helped balance the levels of important immune proteins, like increasing the anti-inflammatory cytokine IL-10, which is vital for managing allergic responses.
Further analysis revealed that taking these fructans together not only improved symptoms but also influenced the gut microbiota in a beneficial way. Certain beneficial bacteria that were reduced during allergy sensitization were restored following fructan intake. This suggests that the combination may help train the gut flora to resist allergic reactions better instead of merely restoring a previous state.
While our study indicates active mechanisms at play with combined intake, it should be noted that isolating the effects of inulin on allergies alone remains difficult based on our current results. Overall, the findings suggest that combining short and long fructans may offer a helpful strategy in reducing the risk of food allergies.
Our findings were promising. The combination of Kes and inulin showed a greater ability to reduce allergy symptoms compared to when each was taken alone. We observed improvement in various measures related to allergic reactions, including reduced total IgA levels and less OVA-specific IgE. Notably, the combination also helped balance the levels of important immune proteins, like increasing the anti-inflammatory cytokine IL-10, which is vital for managing allergic responses.
Further analysis revealed that taking these fructans together not only improved symptoms but also influenced the gut microbiota in a beneficial way. Certain beneficial bacteria that were reduced during allergy sensitization were restored following fructan intake. This suggests that the combination may help train the gut flora to resist allergic reactions better instead of merely restoring a previous state.
While our study indicates active mechanisms at play with combined intake, it should be noted that isolating the effects of inulin on allergies alone remains difficult based on our current results. Overall, the findings suggest that combining short and long fructans may offer a helpful strategy in reducing the risk of food allergies.
Read More
9
Inulin may reduce food allergies
Prebiotic Supplementation During Gestation Induces a Tolerogenic Environment and a Protective Microbiota in Offspring Mitigating Food Allergy.
Strong relevance to allergy treatment.
We investigated whether supplementing pregnant mice with inulin and galacto-oligosaccharides could help their offspring avoid developing food allergies, specifically wheat allergy. Through this study, we found that such prebiotic supplementation during gestation resulted in beneficial changes in the mother’s gut microbiota, which were passed down to the offspring.
The adjusted microbiota in the mothers fostered an increase in protective immune cell types in their young, leading to a more tolerant immune system in the offspring. This supportive environment contributed to reducing the severity of allergy symptoms related to wheat.
Our findings suggest that introducing prebiotics like inulin during pregnancy can create a healthier gut balance and potentially shield children from developing certain food allergies as they grow.
The adjusted microbiota in the mothers fostered an increase in protective immune cell types in their young, leading to a more tolerant immune system in the offspring. This supportive environment contributed to reducing the severity of allergy symptoms related to wheat.
Our findings suggest that introducing prebiotics like inulin during pregnancy can create a healthier gut balance and potentially shield children from developing certain food allergies as they grow.
Read More
9
Cow's milk allergy treatment explored
The Use of an Amino Acid Formula Containing Synbiotics in Infants with Cow's Milk Protein Allergy-Effect on Clinical Outcomes.
Highlights need for specific research
We examined the effectiveness of an amino acid formula that includes prebiotics like inulin and probiotics in infants suffering from cow's milk protein allergy (CMPA). This study, which analyzed data from 148 infants, aimed to see if using this synbiotic formula (AAF-Syn) could improve clinical outcomes compared to a standard amino acid formula without synbiotics.
Our findings revealed that infants on the AAF-Syn formula experienced fewer symptoms, infections, and medication prescriptions. Specifically, there was a significant reduction in symptoms by 37% and a decrease in infections by 35%. Moreover, babies using the synbiotic formula had a better chance of managing their symptoms without needing more hypoallergenic formulas.
Interestingly, those on AAF-Syn could reach a state of being symptom-free sooner, usually around 1.35 years, compared to 1.95 years for those on the standard formula. Additionally, there seemed to be potential cost savings associated with AAF-Syn, amounting to about £452 per infant over the course of treatment.
Although the study highlights the benefits of the entire synbiotic formulation, it didn't isolate inulin’s specific effects on allergies. This means we can see positive trends with the whole formula, but we cannot definitively say how much inulin alone contributes to these benefits. Further research could help clarify this connection, especially since the benefits observed align with previous clinical trials.
Our findings revealed that infants on the AAF-Syn formula experienced fewer symptoms, infections, and medication prescriptions. Specifically, there was a significant reduction in symptoms by 37% and a decrease in infections by 35%. Moreover, babies using the synbiotic formula had a better chance of managing their symptoms without needing more hypoallergenic formulas.
Interestingly, those on AAF-Syn could reach a state of being symptom-free sooner, usually around 1.35 years, compared to 1.95 years for those on the standard formula. Additionally, there seemed to be potential cost savings associated with AAF-Syn, amounting to about £452 per infant over the course of treatment.
Although the study highlights the benefits of the entire synbiotic formulation, it didn't isolate inulin’s specific effects on allergies. This means we can see positive trends with the whole formula, but we cannot definitively say how much inulin alone contributes to these benefits. Further research could help clarify this connection, especially since the benefits observed align with previous clinical trials.
Read More
9
Advax enhances ant venom therapy
Pharmaceutical and preclinical evaluation of Advax adjuvant as a dose-sparing strategy for ant venom immunotherapy.
High relevance to allergy treatment
Our exploration focused on the potential of Advax adjuvant in enhancing Jack Jumper ant venom immunotherapy, aiming to improve outcomes for allergy sufferers with limited venom supplies. This study assessed the stability and immune response generated by low-dose Jack Jumper ant venom (JJAV) when combined with the Advax polysaccharide adjuvant.
We found that the JJAV mixed with Advax maintained its integrity and effectiveness over time, showing promising results in laboratory conditions. Remarkably, mice that received the low-dose JJAV with Advax had higher levels of specific antibodies compared to those who received a much larger dose of JJAV alone.
This suggests that Advax could potentially reduce the amount of venom needed for effective treatment, which is a significant development given the challenges associated with harvesting venom from wild ants. As we move forward, this study sets the stage for a future clinical trial to further test the benefits of Advax in human patients suffering from Jack Jumper ant allergies.
We found that the JJAV mixed with Advax maintained its integrity and effectiveness over time, showing promising results in laboratory conditions. Remarkably, mice that received the low-dose JJAV with Advax had higher levels of specific antibodies compared to those who received a much larger dose of JJAV alone.
This suggests that Advax could potentially reduce the amount of venom needed for effective treatment, which is a significant development given the challenges associated with harvesting venom from wild ants. As we move forward, this study sets the stage for a future clinical trial to further test the benefits of Advax in human patients suffering from Jack Jumper ant allergies.
Read More
User Reviews
USERS' SCORE
Good
Based on 1 Review
8.6
9.5
Effective for pets
Helped wonders for my dog! My three-year-old pit bull had severe allergies and skin infections. After trying all kinds of treatments, I added this Inulin powder with probiotics to her diet. It's a lifesaver! No more itching or infections.
