Last update
5/21/2026
Reviewed By
Reviewed By
Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 10 Researches
7.7
USERS' SCORE
Good
Based on 2 Reviews
8.5
Supplement Facts
Serving Size: 1 Level Teaspoon (approx. 4 g)
Amount Per Serving
%DV
Calories
10
Total Carbohydrate
4 g
1%**
Dietary Fiber
4 g
14%*
Organic Inulin (FOS) (from Blue Agave)
3.3 g
†
Top Medical Research Studies
9.5
Inulin reduces anxiety in migraines
We conducted a fascinating study to understand how inulin supplementation might affect anxiety levels in women suffering from migraines. By design, this was a randomized, double-blind, placebo-controlled trial involving 80 women aged 20 to 50 years old. Participants received either 10 grams of inulin daily or a placebo for 12 weeks.
Our results showed promising findings regarding anxiety. Specifically, we observed a significant decrease in anxiety levels among those taking inulin, with a reduction of 4.37 points compared to the placebo group. This indicates that inulin may play a role in enhancing mental well-being in those experiencing migraine headaches.
It's worth noting that while we found improvements in anxiety and other mental health symptoms such as stress and depression, the quality of life scores did not show a significant difference between the two groups. This could suggest that while inulin helps with anxiety, it might not immediately influence overall quality of life in women with migraines.
Such findings are encouraging and suggest that inulin supplementation can provide a natural avenue to alleviate some mental health challenges associated with migraine episodes. We believe further research could shed more light on these effects.
Our results showed promising findings regarding anxiety. Specifically, we observed a significant decrease in anxiety levels among those taking inulin, with a reduction of 4.37 points compared to the placebo group. This indicates that inulin may play a role in enhancing mental well-being in those experiencing migraine headaches.
It's worth noting that while we found improvements in anxiety and other mental health symptoms such as stress and depression, the quality of life scores did not show a significant difference between the two groups. This could suggest that while inulin helps with anxiety, it might not immediately influence overall quality of life in women with migraines.
Such findings are encouraging and suggest that inulin supplementation can provide a natural avenue to alleviate some mental health challenges associated with migraine episodes. We believe further research could shed more light on these effects.
Read More
8
We investigated how inulin, a type of dietary fiber, can influence anxiety and depression, particularly through its interaction with the gut-brain axis. Our research showed that the timing of inulin consumption significantly affects its ability to alleviate anxiety and depression-like behaviors induced by chronic unpredictable mild stress (CUMS).
Through fecal microbiota transplantation, we confirmed that when inulin is taken at different times, it produces varying effects on anxiety levels. Notably, administering inulin in the evening had a more pronounced impact on reducing inflammation compared to taking it in the morning.
Moreover, metabolomic analysis revealed that certain metabolites, such as fenofibric acid and 4'-Hydroxyfenoprofen glucuronide, could play crucial roles in these effects. Overall, our findings suggest that evening inulin consumption not only improves inflammation but also enhances amino acid metabolism, highlighting the importance of timing in nutritional interventions for anxiety relief.
Through fecal microbiota transplantation, we confirmed that when inulin is taken at different times, it produces varying effects on anxiety levels. Notably, administering inulin in the evening had a more pronounced impact on reducing inflammation compared to taking it in the morning.
Moreover, metabolomic analysis revealed that certain metabolites, such as fenofibric acid and 4'-Hydroxyfenoprofen glucuronide, could play crucial roles in these effects. Overall, our findings suggest that evening inulin consumption not only improves inflammation but also enhances amino acid metabolism, highlighting the importance of timing in nutritional interventions for anxiety relief.
Read More
8
To understand how inulin, a prebiotic, affects anxiety, we investigated its potential benefits in mice undergoing alcohol withdrawal. We created a model of alcohol dependence and treated the mice with inulin, while also using fluvoxamine maleate—a common antidepressant—as a comparison. Over the course of four weeks, we monitored how the mice behaved in tests designed to measure anxiety and depression-like symptoms.
Our findings were promising. Mice treated with inulin showed significant improvements in anxiety-related behaviors. We observed notable changes in their gut microbiota and serotonin (5-HT) metabolism, which are often disrupted in individuals with alcohol dependence. Inulin increased the presence of beneficial bacteria like Faecalibacterium and Roseburia and enhanced the production of short-chain fatty acids (SCFAs), which play a crucial role in gut health.
These results suggest that inulin can offer a nutritional intervention for individuals suffering from anxiety and depression, particularly in the context of alcohol withdrawal. By influencing the delicate balance of gut microbiota and serotonin levels, inulin may help support mental health during recovery from alcohol dependence.
Our findings were promising. Mice treated with inulin showed significant improvements in anxiety-related behaviors. We observed notable changes in their gut microbiota and serotonin (5-HT) metabolism, which are often disrupted in individuals with alcohol dependence. Inulin increased the presence of beneficial bacteria like Faecalibacterium and Roseburia and enhanced the production of short-chain fatty acids (SCFAs), which play a crucial role in gut health.
These results suggest that inulin can offer a nutritional intervention for individuals suffering from anxiety and depression, particularly in the context of alcohol withdrawal. By influencing the delicate balance of gut microbiota and serotonin levels, inulin may help support mental health during recovery from alcohol dependence.
Read More
Most Useful Reviews
9
Brain clarity regained
9 people found this helpful
There is a noticeable result! I had colon issues and began taking a teaspoon of inulin each day with green tea, which was delightful—like childhood toffee. I soon increased it to two teaspoons, and the entire jar was gone within weeks. The effects were almost immediate: my stool improved, and bloating and flatulence vanished. As a bonus, my mental clarity improved, and my anxiety diminished. My mood has brightened significantly! I will certainly purchase more.
Read More
7.5
Anxiety relieved
Excellent! This product offers great calming effects and effectively relieves anxiety. It serves as a substitute for the pharmacy equivalent at a much more advantageous price. I take two capsules daily.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 10 Researches
7.7
- All Researches
9.5
Inulin reduces anxiety in migraines
We conducted a fascinating study to understand how inulin supplementation might affect anxiety levels in women suffering from migraines. By design, this was a randomized, double-blind, placebo-controlled trial involving 80 women aged 20 to 50 years old. Participants received either 10 grams of inulin daily or a placebo for 12 weeks.
Our results showed promising findings regarding anxiety. Specifically, we observed a significant decrease in anxiety levels among those taking inulin, with a reduction of 4.37 points compared to the placebo group. This indicates that inulin may play a role in enhancing mental well-being in those experiencing migraine headaches.
It's worth noting that while we found improvements in anxiety and other mental health symptoms such as stress and depression, the quality of life scores did not show a significant difference between the two groups. This could suggest that while inulin helps with anxiety, it might not immediately influence overall quality of life in women with migraines.
Such findings are encouraging and suggest that inulin supplementation can provide a natural avenue to alleviate some mental health challenges associated with migraine episodes. We believe further research could shed more light on these effects.
Our results showed promising findings regarding anxiety. Specifically, we observed a significant decrease in anxiety levels among those taking inulin, with a reduction of 4.37 points compared to the placebo group. This indicates that inulin may play a role in enhancing mental well-being in those experiencing migraine headaches.
It's worth noting that while we found improvements in anxiety and other mental health symptoms such as stress and depression, the quality of life scores did not show a significant difference between the two groups. This could suggest that while inulin helps with anxiety, it might not immediately influence overall quality of life in women with migraines.
Such findings are encouraging and suggest that inulin supplementation can provide a natural avenue to alleviate some mental health challenges associated with migraine episodes. We believe further research could shed more light on these effects.
Read More
9
Inulin reduces anxiety in stressed mice
We explored the impact of inulin supplementation on anxiety levels in mice subjected to chronic unpredictable mild stress (CUMS). The study looked at how natural prebiotics, such as topinambur powder and chicory root inulin, influence anxiety and cognitive functions.
Over a period of 10 weeks, we administered inulin alongside topinambur to observe any changes in behavior and neurogenesis compared to a control group. Excitingly, we found that both inulin and topinambur, just like fluoxetine—a known antidepressant—significantly reduced anxiety and depression-like behaviors.
Furthermore, we noted improvements in learning and memory skills for the mice receiving these supplements. Fecal microbiota analysis also revealed that inulin played a role in counteracting stress-induced intestinal disruptions, making it a potentially valuable addition to diets for improving mental health under stress.
Overall, our findings suggest that inulin not only helps mitigate anxiety but also supports cognitive functions during stressful conditions in mice. This shines a light on the potential benefits of prebiotics for mental health.
Over a period of 10 weeks, we administered inulin alongside topinambur to observe any changes in behavior and neurogenesis compared to a control group. Excitingly, we found that both inulin and topinambur, just like fluoxetine—a known antidepressant—significantly reduced anxiety and depression-like behaviors.
Furthermore, we noted improvements in learning and memory skills for the mice receiving these supplements. Fecal microbiota analysis also revealed that inulin played a role in counteracting stress-induced intestinal disruptions, making it a potentially valuable addition to diets for improving mental health under stress.
Overall, our findings suggest that inulin not only helps mitigate anxiety but also supports cognitive functions during stressful conditions in mice. This shines a light on the potential benefits of prebiotics for mental health.
Read More
8
We investigated how inulin, a type of dietary fiber, can influence anxiety and depression, particularly through its interaction with the gut-brain axis. Our research showed that the timing of inulin consumption significantly affects its ability to alleviate anxiety and depression-like behaviors induced by chronic unpredictable mild stress (CUMS).
Through fecal microbiota transplantation, we confirmed that when inulin is taken at different times, it produces varying effects on anxiety levels. Notably, administering inulin in the evening had a more pronounced impact on reducing inflammation compared to taking it in the morning.
Moreover, metabolomic analysis revealed that certain metabolites, such as fenofibric acid and 4'-Hydroxyfenoprofen glucuronide, could play crucial roles in these effects. Overall, our findings suggest that evening inulin consumption not only improves inflammation but also enhances amino acid metabolism, highlighting the importance of timing in nutritional interventions for anxiety relief.
Through fecal microbiota transplantation, we confirmed that when inulin is taken at different times, it produces varying effects on anxiety levels. Notably, administering inulin in the evening had a more pronounced impact on reducing inflammation compared to taking it in the morning.
Moreover, metabolomic analysis revealed that certain metabolites, such as fenofibric acid and 4'-Hydroxyfenoprofen glucuronide, could play crucial roles in these effects. Overall, our findings suggest that evening inulin consumption not only improves inflammation but also enhances amino acid metabolism, highlighting the importance of timing in nutritional interventions for anxiety relief.
Read More
8
To understand how inulin, a prebiotic, affects anxiety, we investigated its potential benefits in mice undergoing alcohol withdrawal. We created a model of alcohol dependence and treated the mice with inulin, while also using fluvoxamine maleate—a common antidepressant—as a comparison. Over the course of four weeks, we monitored how the mice behaved in tests designed to measure anxiety and depression-like symptoms.
Our findings were promising. Mice treated with inulin showed significant improvements in anxiety-related behaviors. We observed notable changes in their gut microbiota and serotonin (5-HT) metabolism, which are often disrupted in individuals with alcohol dependence. Inulin increased the presence of beneficial bacteria like Faecalibacterium and Roseburia and enhanced the production of short-chain fatty acids (SCFAs), which play a crucial role in gut health.
These results suggest that inulin can offer a nutritional intervention for individuals suffering from anxiety and depression, particularly in the context of alcohol withdrawal. By influencing the delicate balance of gut microbiota and serotonin levels, inulin may help support mental health during recovery from alcohol dependence.
Our findings were promising. Mice treated with inulin showed significant improvements in anxiety-related behaviors. We observed notable changes in their gut microbiota and serotonin (5-HT) metabolism, which are often disrupted in individuals with alcohol dependence. Inulin increased the presence of beneficial bacteria like Faecalibacterium and Roseburia and enhanced the production of short-chain fatty acids (SCFAs), which play a crucial role in gut health.
These results suggest that inulin can offer a nutritional intervention for individuals suffering from anxiety and depression, particularly in the context of alcohol withdrawal. By influencing the delicate balance of gut microbiota and serotonin levels, inulin may help support mental health during recovery from alcohol dependence.
Read More
In a recent study, we investigated the effects of a specific type of dietary fiber known as oligofructose and a compound called 2'fucosyllactose on anxiety and mood in a group of working adults. This was a well-designed trial, where 92 healthy participants dealing with mild to moderate anxiety were randomly assigned to receive different treatments over five weeks.
Participants were placed into four groups: some received oligofructose alone, others got 2'fucosyllactose, while a third group received a combination of both, and a control group took maltodextrin, which served as a placebo. We looked closely at how these treatments influenced not only the gut microbiome, which is known to play a role in mental health, but also the participants' mood states.
The findings were promising; we observed that both oligofructose and the combination with 2'fucosyllactose positively altered microbial composition. More importantly, these changes were associated with improvements in mood state among the participants. While more research is needed, especially to identify individual responses to 2'fucosyllactose, these results suggest that dietary interventions involving inulin-type fructans can be beneficial in managing anxiety.
Participants were placed into four groups: some received oligofructose alone, others got 2'fucosyllactose, while a third group received a combination of both, and a control group took maltodextrin, which served as a placebo. We looked closely at how these treatments influenced not only the gut microbiome, which is known to play a role in mental health, but also the participants' mood states.
The findings were promising; we observed that both oligofructose and the combination with 2'fucosyllactose positively altered microbial composition. More importantly, these changes were associated with improvements in mood state among the participants. While more research is needed, especially to identify individual responses to 2'fucosyllactose, these results suggest that dietary interventions involving inulin-type fructans can be beneficial in managing anxiety.
Read More
User Reviews
USERS' SCORE
Good
Based on 2 Reviews
8.5
- All Reviews
- Positive Reviews
- Negative Reviews
9
Brain clarity regained
9 people found this helpful
There is a noticeable result! I had colon issues and began taking a teaspoon of inulin each day with green tea, which was delightful—like childhood toffee. I soon increased it to two teaspoons, and the entire jar was gone within weeks. The effects were almost immediate: my stool improved, and bloating and flatulence vanished. As a bonus, my mental clarity improved, and my anxiety diminished. My mood has brightened significantly! I will certainly purchase more.
Read More
7.5
Anxiety relieved
Excellent! This product offers great calming effects and effectively relieves anxiety. It serves as a substitute for the pharmacy equivalent at a much more advantageous price. I take two capsules daily.
Read More
Frequently Asked Questions
7.5
Anxiety relieved
Excellent! This product offers great calming effects and effectively relieves anxiety. It serves as a substitute for the pharmacy equivalent at a much more advantageous price. I take two capsules daily.
9
Brain clarity regained
9 people found this helpful
There is a noticeable result! I had colon issues and began taking a teaspoon of inulin each day with green tea, which was delightful—like childhood toffee. I soon increased it to two teaspoons, and the entire jar was gone within weeks. The effects were almost immediate: my stool improved, and bloating and flatulence vanished. As a bonus, my mental clarity improved, and my anxiety diminished. My mood has brightened significantly! I will certainly purchase more.
8
To understand how inulin, a prebiotic, affects anxiety, we investigated its potential benefits in mice undergoing alcohol withdrawal. We created a model of alcohol dependence and treated the mice with inulin, while also using fluvoxamine maleate—a common antidepressant—as a comparison. Over the course of four weeks, we monitored how the mice behaved in tests designed to measure anxiety and depression-like symptoms.
Our findings were promising. Mice treated with inulin showed significant improvements in anxiety-related behaviors. We observed notable changes in their gut microbiota and serotonin (5-HT) metabolism, which are often disrupted in individuals with alcohol dependence. Inulin increased the presence of beneficial bacteria like Faecalibacterium and Roseburia and enhanced the production of short-chain fatty acids (SCFAs), which play a crucial role in gut health.
These results suggest that inulin can offer a nutritional intervention for individuals suffering from anxiety and depression, particularly in the context of alcohol withdrawal. By influencing the delicate balance of gut microbiota and serotonin levels, inulin may help support mental health during recovery from alcohol dependence.
Our findings were promising. Mice treated with inulin showed significant improvements in anxiety-related behaviors. We observed notable changes in their gut microbiota and serotonin (5-HT) metabolism, which are often disrupted in individuals with alcohol dependence. Inulin increased the presence of beneficial bacteria like Faecalibacterium and Roseburia and enhanced the production of short-chain fatty acids (SCFAs), which play a crucial role in gut health.
These results suggest that inulin can offer a nutritional intervention for individuals suffering from anxiety and depression, particularly in the context of alcohol withdrawal. By influencing the delicate balance of gut microbiota and serotonin levels, inulin may help support mental health during recovery from alcohol dependence.
9.5
Inulin reduces anxiety in migraines
We conducted a fascinating study to understand how inulin supplementation might affect anxiety levels in women suffering from migraines. By design, this was a randomized, double-blind, placebo-controlled trial involving 80 women aged 20 to 50 years old. Participants received either 10 grams of inulin daily or a placebo for 12 weeks.
Our results showed promising findings regarding anxiety. Specifically, we observed a significant decrease in anxiety levels among those taking inulin, with a reduction of 4.37 points compared to the placebo group. This indicates that inulin may play a role in enhancing mental well-being in those experiencing migraine headaches.
It's worth noting that while we found improvements in anxiety and other mental health symptoms such as stress and depression, the quality of life scores did not show a significant difference between the two groups. This could suggest that while inulin helps with anxiety, it might not immediately influence overall quality of life in women with migraines.
Such findings are encouraging and suggest that inulin supplementation can provide a natural avenue to alleviate some mental health challenges associated with migraine episodes. We believe further research could shed more light on these effects.
Our results showed promising findings regarding anxiety. Specifically, we observed a significant decrease in anxiety levels among those taking inulin, with a reduction of 4.37 points compared to the placebo group. This indicates that inulin may play a role in enhancing mental well-being in those experiencing migraine headaches.
It's worth noting that while we found improvements in anxiety and other mental health symptoms such as stress and depression, the quality of life scores did not show a significant difference between the two groups. This could suggest that while inulin helps with anxiety, it might not immediately influence overall quality of life in women with migraines.
Such findings are encouraging and suggest that inulin supplementation can provide a natural avenue to alleviate some mental health challenges associated with migraine episodes. We believe further research could shed more light on these effects.
We explored the potential benefits of combining probiotics and inulin on anxiety levels in patients with coronary artery disease (CAD). In a well-structured study, 96 participants were randomly divided into four groups—one receiving only the probiotic strain, another taking inulin, a third group receiving both, and a fourth group as a placebo. They consumed these supplements for two months while their anxiety and depression levels were regularly assessed.
Our findings revealed that co-supplementation, particularly combining inulin with the probiotic, led to significant improvements in anxiety levels and overall well-being. This combination appeared to provide greater benefits than taking either supplement alone, showing promise for managing psychological symptoms linked to chronic conditions like CAD. However, since all the investigated participants were under chronic stress due to their health issues, we should remain cautious and consider more extensive studies to confirm these positive results for a broader population.
Overall, it looks like inulin, especially when paired with probiotics, contributes positively to reducing anxiety among CAD patients, which could ultimately enhance their quality of life.
Our findings revealed that co-supplementation, particularly combining inulin with the probiotic, led to significant improvements in anxiety levels and overall well-being. This combination appeared to provide greater benefits than taking either supplement alone, showing promise for managing psychological symptoms linked to chronic conditions like CAD. However, since all the investigated participants were under chronic stress due to their health issues, we should remain cautious and consider more extensive studies to confirm these positive results for a broader population.
Overall, it looks like inulin, especially when paired with probiotics, contributes positively to reducing anxiety among CAD patients, which could ultimately enhance their quality of life.
References
- Chen P, Chen F, Hou T, Hu X, Xia C, et al. Administration time modify the anxiolytic and antidepressant effects of inulin via gut-brain axis. Int J Biol Macromol. 2025;288:138698. 10.1016/j.ijbiomac.2024.138698
- Li K, Wei W, Xu C, Lian X, Bao J, et al. Prebiotic inulin alleviates anxiety and depression-like behavior in alcohol withdrawal mice by modulating the gut microbiota and 5-HT metabolism. Phytomedicine. 2024;135:156181. 10.1016/j.phymed.2024.156181
- Vajdi M, Khorvash F, Askari G. A randomized, double-blind, placebo-controlled parallel trial to test the effect of inulin supplementation on migraine headache characteristics, quality of life and mental health symptoms in women with migraine. Food Funct. 2024;15:10088. 10.1039/d4fo02796e
- Jackson PP, Wijeyesekera A, Williams CM, Theis S, van Harsselaar J, et al. Inulin-type fructans and 2'fucosyllactose alter both microbial composition and appear to alleviate stress-induced mood state in a working population compared to placebo (maltodextrin): the EFFICAD Trial, a randomized, controlled trial. Am J Clin Nutr. 2023;118:938. 10.1016/j.ajcnut.2023.08.016
- Szala-Rycaj J, Szewczyk A, Zagaja M, Kaczmarczyk-Ziemba A, Maj M, et al. The Influence of Topinambur and Inulin Preventive Supplementation on Microbiota, Anxious Behavior, Cognitive Functions and Neurogenesis in Mice Exposed to the Chronic Unpredictable Mild Stress. Nutrients. 2023;15. 10.3390/nu15092041
- Amadieu C, Coste V, Neyrinck AM, Thijssen V, Leyrolle Q, et al. Restoring an adequate dietary fiber intake by inulin supplementation: a pilot study showing an impact on gut microbiota and sociability in alcohol use disorder patients. Gut Microbes. 2022;14:2007042. 10.1080/19490976.2021.2007042
- Moludi J, Khedmatgozar H, Nachvak SM, Abdollahzad H, Moradinazar M, et al. The effects of co-administration of probiotics and prebiotics on chronic inflammation, and depression symptoms in patients with coronary artery diseases: a randomized clinical trial. Nutr Neurosci. 2022;25:1659. 10.1080/1028415X.2021.1889451
- Guo L, Xiao P, Zhang X, Yang Y, Yang M, et al. Inulin ameliorates schizophrenia modulation of the gut microbiota and anti-inflammation in mice. Food Funct. 2021;12:1156. 10.1039/d0fo02778b
- Morshedi M, Valenlia KB, Hosseinifard ES, Shahabi P, Abbasi MM, et al. Beneficial psychological effects of novel psychobiotics in diabetic rats: the interaction among the gut, blood and amygdala. J Nutr Biochem. 2018;57:145. 10.1016/j.jnutbio.2018.03.022
- Barrera-Bugueño C, Realini O, Escobar-Luna J, Sotomayor-Zárate R, Gotteland M, et al. Anxiogenic effects of a Lactobacillus, inulin and the synbiotic on healthy juvenile rats. Neuroscience. 2017;359:18. 10.1016/j.neuroscience.2017.06.064
