'
NOW Supplements Inulin Prebiotic Powder
SCIENTIFIC SCORE
Possibly Effective
Based on 16 Researches
7.7
USERS' SCORE
Moderately Good
Based on 1 Review
7.7
Supplement Facts
Serving Size: 1 Level Teaspoon (approx. 4 g)
Amount Per Serving
%DV
Calories
10 
 
Total Carbohydrate
4 g
1%**
Dietary Fiber
4 g
14%*
Organic Inulin (FOS) (from Blue Agave)
3.3 g

Top Medical Research Studies

9.5
Inulin reduces neonatal diarrhea incidence
Dietary Inulin Regulated Gut Microbiota and Improved Neonatal Health in a Pregnant Sow Model.
Directly impacts piglet diarrhea
We explored the effect of inulin, a type of dietary fiber, on the health of piglets born to sows during pregnancy. In our study, multiparous sows were divided into two groups. One group received a diet without inulin, while the other group was fed a diet containing 1.6% inulin.

We observed that the inclusion of inulin in the diet significantly reduced the incidences of diarrhea in piglets. Specifically, the sows that consumed inulin had lower levels of urea nitrogen in their colostrum, which correlated with better health outcomes for their piglets. This led to increased survival rates and overall growth of the piglets, providing encouraging evidence that inulin can play an important role in enhancing neonatal health.

Overall, our findings suggest that maternal dietary fiber, particularly inulin, not only supports the health of the sows but also positively influences the wellbeing of their offspring, notably in reducing the risk of diarrhea in newborn piglets.
Read More
8
Maternal inulin reduces piglet diarrhea
Maternal dietary inulin intake during late gestation and lactation ameliorates intestinal oxidative stress in piglets with the involvements of gut microbiota and bile acids metabolism.
Study highlights inulin's effectiveness
We aimed to understand how inulin in a mother's diet affects diarrhea in piglets. In our study, we observed 40 sows divided into two groups; one received a standard diet, while the other had 2% of their wheat bran replaced with inulin during late gestation and lactation. The results were quite promising.

The piglets from the sows consuming inulin showed a lower rate of diarrhea, especially during the weaning period, compared to those whose mothers had the regular diet. This improvement suggests that inulin may have a protective role in enhancing gut health for piglets. Furthermore, we noted that the growth rate of these piglets was better during suckling.

Interestingly, those piglets also exhibited markers of reduced oxidative stress in their systems. In essence, incorporating inulin into the maternal diet seems to not only reduce diarrhea in piglets but also support their overall well-being. This research sheds light on the potential benefits of dietary inulin in livestock health management.
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9
Inulin aids vaccine stability
Preparation and preclinical evaluation of a freeze-dried formulation of a novel combined multivalent whole-cell/B-subunit oral vaccine against enterotoxigenic Escherichia coli diarrhea.
Moderate relevance to treatment.
We examined a novel approach to developing a more effective oral vaccine against enterotoxigenic Escherichia coli (ETEC), a leading cause of diarrhea, particularly in children from low-income countries. The research focused on using a freeze-dried formulation of the vaccine, which combines whole E. coli cells and a subunit of enterotoxin B. A key component of our study was the inclusion of inulin, a stabilizer, designed to enhance the viability and effectiveness of the vaccine.

During our assessments, we noted that while inulin successfully aided in maintaining the overall structure of the bacteria during the freeze-drying process, it did not completely eliminate aggregation. However, it was effective in recovering the important colonization factors and B subunit antigens crucial for generating an immune response.

When we administered the freeze-dried vaccine, alongside an adjuvant known as dmLT, to mice, we observed strong antibody responses in the intestinal and serum regions. These responses were promisingly on par with those achieved using the liquid version of the vaccine. This suggests that inulin's role as a stabilizer could be pivotal in formulating a stable, long-lasting oral vaccine that retains its immunogenic properties.

In summary, our findings indicate that while inulin contributes positively to the vaccine's stability, it doesn't specifically address diarrhea on its own. Instead, we made strides toward an innovative solution for a serious health issue with retained efficacy in a freeze-dried format.
Read More

Most Useful Reviews

0
Caused massive diarrhea
Horrible stuff caused diarrhoea. I started with a small amount and gradually increased to the recommended dose. However, upon taking one teaspoon daily, I suffered from massive, blowout, liquid diarrohea. I couldn’t leave the house without Imodium. Once I realised what caused the issue and stopped using it, the diarrhoea disappeared. Many others have suggested this product might be fake, as I have taken other inulin products without any problems.
Read More

Medical Researches

SCIENTIFIC SCORE
Possibly Effective
Based on 16 Researches
7.7
9.5
Inulin reduces neonatal diarrhea incidence
Dietary Inulin Regulated Gut Microbiota and Improved Neonatal Health in a Pregnant Sow Model.
Directly impacts piglet diarrhea
We explored the effect of inulin, a type of dietary fiber, on the health of piglets born to sows during pregnancy. In our study, multiparous sows were divided into two groups. One group received a diet without inulin, while the other group was fed a diet containing 1.6% inulin.

We observed that the inclusion of inulin in the diet significantly reduced the incidences of diarrhea in piglets. Specifically, the sows that consumed inulin had lower levels of urea nitrogen in their colostrum, which correlated with better health outcomes for their piglets. This led to increased survival rates and overall growth of the piglets, providing encouraging evidence that inulin can play an important role in enhancing neonatal health.

Overall, our findings suggest that maternal dietary fiber, particularly inulin, not only supports the health of the sows but also positively influences the wellbeing of their offspring, notably in reducing the risk of diarrhea in newborn piglets.
Read More
9.5
Exploring inulin's protective effects
Probiotic/prebiotic correction for adverse effects of iron fortification on intestinal resistance to Salmonella infection in weaning mice.
Addressing iron fortification risks
We explored the impact of inulin on gut health, particularly its ability to combat diarrhea linked to iron fortification. In a study involving weaning mice, the introduction of iron through ferrous sulfate increased the diversity of gut bacteria but also led to a decline in beneficial bacteria, like Lactobacillus.

Notably, we observed that mice receiving a high dose of iron experienced heightened symptoms when infected with the pathogen Salmonella. These symptoms included significant weight and appetite loss, and decreased survival rates. However, when we supplemented the mice with inulin before exposure to the infection, these adverse effects were significantly reversed.

The research showed that inulin not only helped improve overall gut health but also alleviated the intestinal damage caused by iron fortification. This suggests that inulin could serve as a practical measure to mitigate the negative impacts of iron fortification on digestive health, particularly in populations vulnerable to diarrhea.
Read More
9
Inulin improves antibiotic-related diarrhea
New compound probiotic beverage protects against antibiotic-associated diarrhea in mice by modulating the microbiota.
Moderate relevance to topic
We examined how a specially designed probiotic beverage containing a higher level of inulin can help combat diarrhea caused by antibiotics. In our study, we utilized a group of mice that had been treated with three different antibiotics for two weeks. This allowed us to closely monitor the effects of the probiotics over time.

Among the groups tested, one group—referred to as S1—stood out due to its elevated inulin content. We observed that this group returned to normal gut health more quickly than those that did not receive the S1 formulation. Specifically, it was noted that the balance of beneficial bacteria in the gut improved significantly, with an increase in the Firmicutes phylum.

Ultimately, the introduction of this new probiotic combination not only aided in the recovery of gut health but also showcased that the S1 formula was the most effective in restoring the microbiota. Our findings suggest that incorporating inulin into probiotic beverages can offer substantial benefits in managing antibiotic-associated diarrhea.
Read More
9
Inulin improves gut health in giardiasis
Prophylactic Potential of Synbiotic (Lactobacillus casei and Inulin) in Malnourished Murine Giardiasis: an Immunological and Ultrastructural Study.
Limited isolation of inulin's effects
We explored the effects of a synbiotic treatment, which included Lactobacillus casei and inulin, on malnourished mice infected with Giardia, a parasite that causes diarrhea. The study aimed to establish whether this combination could reduce the severity of diarrhea and improve overall health in these vulnerable mice.

Our findings showed that prior administration of the synbiotic led to several positive outcomes. The treated mice gained body mass and improved their small intestine health, with higher counts of beneficial lactobacilli. The severity of giardiasis was notably reduced, evidenced by decreases in harmful cysts and trophozoites.

Additionally, we observed that this synbiotic treatment enhanced the immune response in the mice. Specifically, there was an increase in beneficial antibodies and cytokines, which are crucial for fighting infections. Histological and microscopic examinations revealed that the synbiotic helped maintain better gut structure, leading to reduced cellular damage compared to untreated infected mice.

While this study highlights the effectiveness of the synbiotic combination, it does not isolate the specific impact of inulin on diarrhea, making it challenging to attribute all benefits directly to inulin alone. However, the overall results suggest that incorporating inulin through a synbiotic approach could be promising for supporting gut health, especially in those at risk of malnutrition and related infections.
Read More
9
Inulin aids vaccine stability
Preparation and preclinical evaluation of a freeze-dried formulation of a novel combined multivalent whole-cell/B-subunit oral vaccine against enterotoxigenic Escherichia coli diarrhea.
Moderate relevance to treatment.
We examined a novel approach to developing a more effective oral vaccine against enterotoxigenic Escherichia coli (ETEC), a leading cause of diarrhea, particularly in children from low-income countries. The research focused on using a freeze-dried formulation of the vaccine, which combines whole E. coli cells and a subunit of enterotoxin B. A key component of our study was the inclusion of inulin, a stabilizer, designed to enhance the viability and effectiveness of the vaccine.

During our assessments, we noted that while inulin successfully aided in maintaining the overall structure of the bacteria during the freeze-drying process, it did not completely eliminate aggregation. However, it was effective in recovering the important colonization factors and B subunit antigens crucial for generating an immune response.

When we administered the freeze-dried vaccine, alongside an adjuvant known as dmLT, to mice, we observed strong antibody responses in the intestinal and serum regions. These responses were promisingly on par with those achieved using the liquid version of the vaccine. This suggests that inulin's role as a stabilizer could be pivotal in formulating a stable, long-lasting oral vaccine that retains its immunogenic properties.

In summary, our findings indicate that while inulin contributes positively to the vaccine's stability, it doesn't specifically address diarrhea on its own. Instead, we made strides toward an innovative solution for a serious health issue with retained efficacy in a freeze-dried format.
Read More

User Reviews

USERS' SCORE
Moderately Good
Based on 1 Review
7.7
0
Caused massive diarrhea
Horrible stuff caused diarrhoea. I started with a small amount and gradually increased to the recommended dose. However, upon taking one teaspoon daily, I suffered from massive, blowout, liquid diarrohea. I couldn’t leave the house without Imodium. Once I realised what caused the issue and stopped using it, the diarrhoea disappeared. Many others have suggested this product might be fake, as I have taken other inulin products without any problems.
Read More
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