Our study aimed to explore how a prebiotic called fructooligosaccharide (FOS)-inulin affects chickens' ability to combat food poisoning caused by Salmonella Enteritidis (SE). We focused on chicken macrophages, which are important immune cells that help eliminate this pathogen. Using an in vitro model, we treated the HD11 macrophage cell line with FOS-inulin and assessed its ability to phagocytose and kill SE, as well as the production of inflammatory markers.
The results were quite revealing. After treatment with FOS-inulin, we found that the HD11 cells contained significantly fewer viable SE compared to those that were untreated, suggesting that this prebiotic supports macrophage function in eliminating the bacteria. However, it’s worth noting that FOS-inulin did not appear to influence the overall phagocytosis process or the production of nitric oxide, a key player in the immune response.
Additionally, we observed that levels of IL-1β, an important inflammatory cytokine, were significantly reduced in macrophages treated with FOS-inulin. This indicates that FOS-inulin can help modulate the innate immune response, making it potentially beneficial for enhancing the body's defense against foodborne pathogens while also reducing excessive inflammation.
Read More
9
Inulin aids gut health during infection
Probiotic/prebiotic correction for adverse effects of iron fortification on intestinal resistance to Salmonella infection in weaning mice.
We investigated how inulin, a popular prebiotic, affects gut health during instances of food poisoning, particularly following iron fortification. In our study, we observed that iron fortification can increase diarrhea risk in weaning mice and, unfortunately, make them more susceptible to infections like Salmonella.
Mice given a diet with 500 ppm of iron showed more severe symptoms when infected, including weight loss and reduced appetite. However, we found that supplementing their diet with inulin for just seven days before infection significantly improved their health outcomes. The presence of inulin helped reduce the abundance of the harmful pathogen, Salmonella, in their intestines and alleviated gut damage caused by iron.
Our results suggest that inulin acts as a protective barrier, improving gut health by fostering a balance in gut microbiota during challenging times. This research highlights the potential of using inulin to mitigate the harmful side effects of iron supplementation, offering valuable insights for dietary considerations, particularly among vulnerable populations like children.
Read More
Most Useful Reviews
9
Long-term relief
8 people found this helpful
This product has improved my constipation, which I have struggled with for 20-30 years. Having only one bowel movement every two to three days, I was in search of effective remedies. Prebiotics are crucial for gut health, and this one pairs well with probiotics, enhancing results. I recommend taking 2-4 teaspoons daily; you’ll notice clear improvements after one or two days!
Read More
9
Effective for constipation
6 people found this helpful
I found this effective for constipation! Usually, I wouldn't notice it for about three days, so I tried various remedies. However, when I drank it, everything came out daily. It's tasteless and odourless, so I sometimes add it to my morning coffee or even to udon or ramen, though it may not be as effective if mixed with cold food. Mixing it with warm food is better! I like using three transparent spoons from a dessert shop, but four cups work as well, so it's best to find the amount that suits you. That amount lasted me about six weeks!
Read More
7.5
Supports gut health
5 people found this helpful
Inulin supports my intestinal health and function excellently. Its pleasant taste slightly sweetens foods and drinks without negatively impacting blood glucose levels. It aids my metabolism, alleviates constipation, and works even better when combined with a probiotic, boosting my immune system. I appreciate the large packaging and the product's quality.
We investigated how inulin, a popular prebiotic, affects gut health during instances of food poisoning, particularly following iron fortification. In our study, we observed that iron fortification can increase diarrhea risk in weaning mice and, unfortunately, make them more susceptible to infections like Salmonella.
Mice given a diet with 500 ppm of iron showed more severe symptoms when infected, including weight loss and reduced appetite. However, we found that supplementing their diet with inulin for just seven days before infection significantly improved their health outcomes. The presence of inulin helped reduce the abundance of the harmful pathogen, Salmonella, in their intestines and alleviated gut damage caused by iron.
Our results suggest that inulin acts as a protective barrier, improving gut health by fostering a balance in gut microbiota during challenging times. This research highlights the potential of using inulin to mitigate the harmful side effects of iron supplementation, offering valuable insights for dietary considerations, particularly among vulnerable populations like children.
Read More
8
FOS-inulin aids Salmonella defense
Effects of fructooligosaccharide-inulin on Salmonella-killing and inflammatory gene expression in chicken macrophages.
Our study aimed to explore how a prebiotic called fructooligosaccharide (FOS)-inulin affects chickens' ability to combat food poisoning caused by Salmonella Enteritidis (SE). We focused on chicken macrophages, which are important immune cells that help eliminate this pathogen. Using an in vitro model, we treated the HD11 macrophage cell line with FOS-inulin and assessed its ability to phagocytose and kill SE, as well as the production of inflammatory markers.
The results were quite revealing. After treatment with FOS-inulin, we found that the HD11 cells contained significantly fewer viable SE compared to those that were untreated, suggesting that this prebiotic supports macrophage function in eliminating the bacteria. However, it’s worth noting that FOS-inulin did not appear to influence the overall phagocytosis process or the production of nitric oxide, a key player in the immune response.
Additionally, we observed that levels of IL-1β, an important inflammatory cytokine, were significantly reduced in macrophages treated with FOS-inulin. This indicates that FOS-inulin can help modulate the innate immune response, making it potentially beneficial for enhancing the body's defense against foodborne pathogens while also reducing excessive inflammation.
Read More
User Reviews
USERS' SCORE
Moderately Good
Based on 33 Reviews
7.7
All Reviews
Positive Reviews
Negative Reviews
9
Long-term relief
8 people found this helpful
This product has improved my constipation, which I have struggled with for 20-30 years. Having only one bowel movement every two to three days, I was in search of effective remedies. Prebiotics are crucial for gut health, and this one pairs well with probiotics, enhancing results. I recommend taking 2-4 teaspoons daily; you’ll notice clear improvements after one or two days!
Read More
9
Effective for constipation
6 people found this helpful
I found this effective for constipation! Usually, I wouldn't notice it for about three days, so I tried various remedies. However, when I drank it, everything came out daily. It's tasteless and odourless, so I sometimes add it to my morning coffee or even to udon or ramen, though it may not be as effective if mixed with cold food. Mixing it with warm food is better! I like using three transparent spoons from a dessert shop, but four cups work as well, so it's best to find the amount that suits you. That amount lasted me about six weeks!
Read More
7.5
Supports gut health
5 people found this helpful
Inulin supports my intestinal health and function excellently. Its pleasant taste slightly sweetens foods and drinks without negatively impacting blood glucose levels. It aids my metabolism, alleviates constipation, and works even better when combined with a probiotic, boosting my immune system. I appreciate the large packaging and the product's quality.
Read More
7.5
Light stomach feeling
3 people found this helpful
Inulin works like a charm! I take it with probiotics at night. After using inulin, my stomach feels light, and food is digested much better. I'm very pleased with the results.
Read More
9
Natural remedy
2 people found this helpful
Very effective in easing constipation, inulin is a natural food for beneficial gut bacteria, supporting easy excretion.
Food poisoning, also known as foodborne illness, occurs when you consume contaminated food or beverages. This contamination can result from bacteria, viruses, parasites, or chemical substances that have infected the food. Common symptoms of food poisoning include nausea, vomiting, diarrhea, abdominal cramps, and fever, which usually appear within hours or days following the consumption of contaminated food. While most cases resolve on their own within a few days, some can lead to severe complications, especially in vulnerable populations such as young children, the elderly, and individuals with weakened immune systems.
To prevent food poisoning, it's essential to practice safe food handling techniques such as washing hands, cooking food to the appropriate temperatures, and avoiding cross-contamination between raw and cooked foods. Keeping your refrigerator at the correct temperature and being mindful of expiration dates can also help reduce the risk of foodborne illnesses. If you suspect that you have food poisoning, particularly if symptoms are severe or persistent, it's important to seek medical attention.
Prebiotic fiber inulin is a naturally occurring carbohydrate found in a variety of plants, particularly in roots and tubers such as chicory, garlic, leeks, and onions. As a soluble fiber, it is not digested in the small intestine but rather fermented by beneficial gut bacteria in the large intestine. This fermentation process helps promote the growth of beneficial bacteria, which can support gut health, improve digestion, and enhance the absorption of certain nutrients. Increasing dietary intake of prebiotic fibers like inulin can contribute to a healthier microbiome.
In addition to its benefits for gut health, inulin can also help to enhance feelings of fullness and reduce appetite, making it a popular ingredient in weight management products. It is often added to food and beverage items as a texturizer or sweetener because it offers a mildly sweet flavor without contributing significant calories. Given its numerous health benefits, inulin is frequently emphasized in discussions about dietary fiber and overall nutrition, making it a valuable component of a balanced diet.
Based on user reviews, the time it typically takes to see results from taking this supplement for food poisoning can vary, but many users report noticeable improvements relatively quickly. For instance, some users have mentioned experiencing significant relief from constipation and overall digestive issues within a day or two of starting the supplement, indicating that effectiveness can be quite rapid. One reviewer noted that they noticed improvements after just one or two days of consistent use Read Review. Another user mentioned feeling refreshed within about three hours of consumption Read Review.
However, results can depend on individual circumstances and the specific gastrointestinal issues experienced, as some users might take longer to see the full benefits. Overall, if you're considering this supplement for food poisoning, you may find that within a few days to a week, you should start to notice improvements in your digestive comfort and regularity, especially when combined with probiotics as highlighted by several users Read Review.
The scientific research indicates potential benefits of certain prebiotics, specifically inulin and fructooligosaccharides (FOS), in managing food poisoning related to pathogens like Salmonella. One study demonstrated that inulin can mitigate adverse effects associated with iron supplementation, which can make individuals more susceptible to infections like Salmonella. In this study, mice supplemented with inulin showed improved health outcomes and reduced pathogen abundance in the gut during food poisoning challenges [1]. This suggests that inulin acts as a protective barrier that promotes gut health during such distressing times, particularly in populations that may be more vulnerable, such as children.
Similarly, another study focused on the impact of FOS-inulin on chickens provided compelling data. It was found that FOS-inulin enhanced the ability of chicken macrophages to combat Salmonella Enteritidis, indicating that it aids the immune system in eliminating this foodborne pathogen. Macrophages treated with FOS-inulin contained fewer viable bacteria, hinting at its supportive role in immune defense [2]. While the current data is specific to animal models, these findings suggest that prebiotics like inulin and FOS could be valuable allies in the fight against foodborne illnesses, especially as research continues to explore their effects in human populations.
Based on user reviews, many individuals have reported notable improvements in their gastrointestinal symptoms, particularly constipation, after incorporating this supplement into their routine. Users frequently mention beginning to experience relief within just a day or two of initial use. For example, one reviewer shared that after struggling with constipation for decades, the product allowed them to have regular bowel movements after just one or two days of consistent use Read Review. Multiple users support this claim, indicating that they have found success with daily intake, leading to improved digestive health and overall comfort Read Review.
Moreover, those who combined the supplement with probiotics reported even greater effects, as it not only alleviated constipation but also supported better digestion and gut health Read Review. Some users noted that it was particularly beneficial in softening stools and improving the regularity of bowel movements, with one testimonial highlighting significant improvement in stool formation and digestion for their son after using the product Read Review. However, it is important to note that individual results can vary; while many users see positive results quickly, others may require a longer period to experience the full benefits of this supplement.
Users frequently report enhanced effectiveness when combining this supplement, inulin, with probiotics for managing gastrointestinal issues, including those stemming from food poisoning. Several reviewers noted that taking inulin alongside probiotics significantly improves digestive health and overall intestinal function. For example, one user emphasized the positive results they experienced when consuming inulin at night paired with probiotics, stating their stomach felt lighter and digestion improved markedly Read Review. Another reviewer echoed these sentiments, claiming that inulin is an excellent food source for probiotics, which can dramatically enhance outcomes Read Review.
Moreover, individuals who have experienced food poisoning reported positive results after using inulin in conjunction with Lactofiltrum probiotics, suggesting that this combination may expedite recovery and improve gut health Read Review. Many users highlighted these benefits, indicating that the synergistic effects of inulin and probiotics offer significant relief while supporting proper digestive function and regularity. Overall, if you are considering inulin for food-related gastrointestinal issues, pairing it with probiotics appears to be a highly recommended strategy among users Read Review.
9
Long-term relief
8 people found this helpful
This product has improved my constipation, which I have struggled with for 20-30 years. Having only one bowel movement every two to three days, I was in search of effective remedies. Prebiotics are crucial for gut health, and this one pairs well with probiotics, enhancing results. I recommend taking 2-4 teaspoons daily; you’ll notice clear improvements after one or two days!
9
Refreshing experience
1 people found this helpful
I’ve tried various supplements and fermented foods to enhance my intestinal environment, but this has been the most effective. After consuming it, I felt a refreshing effect within about three hours. I plan to continue buying it. I took between 5g and 10g at a time, mixing it with herbal tea. Its sweetness makes it a great addition to juice, and it pairs well with cocoa and hot beverages.
7.5
Effective supplement
1 people found this helpful
I combined inulin with probiotics and found the quality and packaging excellent. It effectively eliminates constipation and enhances gastrointestinal movement, making it suitable for all ages on specific diets.
7.5
Light stomach feeling
3 people found this helpful
Inulin works like a charm! I take it with probiotics at night. After using inulin, my stomach feels light, and food is digested much better. I'm very pleased with the results.
9
Improved digestion
1 people found this helpful
Great product! I bought it for my mother, who has had issues with her intestines and food digestion. After starting inulin along with Betaine, her digestion has improved significantly. The brand is reliable, and the website is easy to use for purchasing and delivery.
9
Regulated digestion
2 people found this helpful
I became acquainted with this prebiotic when introducing the Nemecheka protocol for my son. It is recommended for this protocol! He has experienced improved stool and digestion, and his microflora is now normal. The stool is more formed, and I've noticed all the changes necessary for the protocol!
9
Excellent results
1 people found this helpful
Inulin enhances the action of probiotics! When purchasing probiotics, consider their food to ensure at least 10% survive. Inulin is the favourite food for beneficial bacteria! I take a teaspoon with each probiotic, and the results are superb, as expected.
7.5
Quick recovery
86 people found this helpful
The large jar has a sweet, sticky gum-like taste. I purchased it hoping to improve my digestive system. I had taken Lactofiltrum probiotics after experiencing food poisoning, which helped me recover quickly. I believe these prebiotics will provide similar benefits. However, I find that in room temperature water, it coagulates and does not dissolve completely.
9
Inulin aids gut health during infection
Probiotic/prebiotic correction for adverse effects of iron fortification on intestinal resistance to Salmonella infection in weaning mice.
We investigated how inulin, a popular prebiotic, affects gut health during instances of food poisoning, particularly following iron fortification. In our study, we observed that iron fortification can increase diarrhea risk in weaning mice and, unfortunately, make them more susceptible to infections like Salmonella.
Mice given a diet with 500 ppm of iron showed more severe symptoms when infected, including weight loss and reduced appetite. However, we found that supplementing their diet with inulin for just seven days before infection significantly improved their health outcomes. The presence of inulin helped reduce the abundance of the harmful pathogen, Salmonella, in their intestines and alleviated gut damage caused by iron.
Our results suggest that inulin acts as a protective barrier, improving gut health by fostering a balance in gut microbiota during challenging times. This research highlights the potential of using inulin to mitigate the harmful side effects of iron supplementation, offering valuable insights for dietary considerations, particularly among vulnerable populations like children.
8
FOS-inulin aids Salmonella defense
Effects of fructooligosaccharide-inulin on Salmonella-killing and inflammatory gene expression in chicken macrophages.
Our study aimed to explore how a prebiotic called fructooligosaccharide (FOS)-inulin affects chickens' ability to combat food poisoning caused by Salmonella Enteritidis (SE). We focused on chicken macrophages, which are important immune cells that help eliminate this pathogen. Using an in vitro model, we treated the HD11 macrophage cell line with FOS-inulin and assessed its ability to phagocytose and kill SE, as well as the production of inflammatory markers.
The results were quite revealing. After treatment with FOS-inulin, we found that the HD11 cells contained significantly fewer viable SE compared to those that were untreated, suggesting that this prebiotic supports macrophage function in eliminating the bacteria. However, it’s worth noting that FOS-inulin did not appear to influence the overall phagocytosis process or the production of nitric oxide, a key player in the immune response.
Additionally, we observed that levels of IL-1β, an important inflammatory cytokine, were significantly reduced in macrophages treated with FOS-inulin. This indicates that FOS-inulin can help modulate the innate immune response, making it potentially beneficial for enhancing the body's defense against foodborne pathogens while also reducing excessive inflammation.
References
Lin F, Wu H, Zeng M, Yu G, Dong S, et al. Probiotic/prebiotic correction for adverse effects of iron fortification on intestinal resistance to Salmonella infection in weaning mice. Food Funct. 2018;9:1070. doi:10.1039/c7fo00990a
Babu US, Sommers K, Harrison LM, Balan KV. Effects of fructooligosaccharide-inulin on Salmonella-killing and inflammatory gene expression in chicken macrophages. Vet Immunol Immunopathol. 2012;149:92. doi:10.1016/j.vetimm.2012.05.003