Overview
SCIENTIFIC SCORE
Moderately Effective
Based on 8 Researches
8.4
USERS' SCORE
Moderately Good
Based on 16 Reviews
7
Supplement Facts
Serving Size: 1 Veg Capsule
Amount Per Serving
%DV
Choline (from 630 mg Choline Bitartrate)
250 mg
45%
Inositol
250 mg
†
Top Medical Research Studies
9
We explored the effects of myo-inositol (MYO) on acne among young women diagnosed with polycystic ovary syndrome (PCOS). The study included 50 participants who underwent treatment with MYO for six months, focusing on its potential to improve the often frustrating skin issues linked to PCOS.
At the beginning and after the treatment period, we measured various factors including levels of hormones and insulin, as well as the severity of acne.
Remarkably, after three months of MYO therapy, we observed significant reductions in hormone levels associated with PCOS, particularly testosterone and insulin. After six months, both hirsutism and acne symptoms showed notable improvement among the participants.
This research highlights MYO as a promising, safe treatment option for alleviating acne symptoms in individuals with PCOS. Its ability to improve metabolic conditions while managing acne is a fascinating development for women seeking effective solutions for their skin concerns.
At the beginning and after the treatment period, we measured various factors including levels of hormones and insulin, as well as the severity of acne.
Remarkably, after three months of MYO therapy, we observed significant reductions in hormone levels associated with PCOS, particularly testosterone and insulin. After six months, both hirsutism and acne symptoms showed notable improvement among the participants.
This research highlights MYO as a promising, safe treatment option for alleviating acne symptoms in individuals with PCOS. Its ability to improve metabolic conditions while managing acne is a fascinating development for women seeking effective solutions for their skin concerns.
Read More
9.5
Myo-inositol improves adult acne
We conducted an open-label clinical study to explore how a peel-off facial mask containing myoinositol and trehalose-loaded liposomes could improve adult female acne (AFA). By applying the mask every other day for 60 days, we examined its effects on acne lesions, sebum production, and overall skin health.
During the study, we measured changes in the number of acne lesions and collected skin biopsy samples to analyze hormone levels and markers of autophagy—a process that helps the skin repair and rejuvenate itself. Our findings showed a significant reduction in various types of acne lesions, as well as a decrease in sebum production.
Notably, we observed a decrease in androgen levels in the skin, which is crucial since higher androgens can exacerbate acne. Additionally, levels of beclin-1, a marker associated with skin autophagy, increased, suggesting that the mask not only improved the appearance of acne but also encouraged healthier skin processes.
Overall, the peel-off mask with myoinositol effectively addresses some underlying factors contributing to acne in women, providing a promising option for those struggling with adult acne.
During the study, we measured changes in the number of acne lesions and collected skin biopsy samples to analyze hormone levels and markers of autophagy—a process that helps the skin repair and rejuvenate itself. Our findings showed a significant reduction in various types of acne lesions, as well as a decrease in sebum production.
Notably, we observed a decrease in androgen levels in the skin, which is crucial since higher androgens can exacerbate acne. Additionally, levels of beclin-1, a marker associated with skin autophagy, increased, suggesting that the mask not only improved the appearance of acne but also encouraged healthier skin processes.
Overall, the peel-off mask with myoinositol effectively addresses some underlying factors contributing to acne in women, providing a promising option for those struggling with adult acne.
Read More
8
We analyzed the effectiveness of myo-inositol supplementation on acne in women with polycystic ovary syndrome (PCOS). In a retrospective study involving 200 patients over six months, we found that the supplement significantly lowered levels of testosterone and DHEAS, leading to improvements in acne and hirsutism. The supplements not only enhanced clinical symptoms but also positively affected patients' quality of life. Encouragingly, there were no reported side effects, suggesting good compliance among participants. However, more long-term studies are necessary to validate these promising findings.
Read More
Most Useful Reviews
9
Period regularity
16 people found this helpful
For those suffering from polycystic ovaries, I highly recommend this treatment. After two months, my periods returned, chronic pain disappeared, and my acne has improved significantly. Using a higher dosage is more effective; I take two to three tablets daily.
Read More
9
Acne improvement
3 people found this helpful
This product has greatly improved my facial acne and regulates my insulin levels, much more effectively than glucophage for cysts. I take it after meals, one or two pills, and the results are remarkable without needing a diet.
Read More
9
Cognitive support
1 people found this helpful
I take this daily and have noticed benefits such as improved cognitive function and a reduction in my acne. It feels perfect to have both elements combined in one capsule.
Read More
Medical Researches
SCIENTIFIC SCORE
Moderately Effective
Based on 8 Researches
8.4
- All Researches
9.5
Myo-inositol improves adult acne
We conducted an open-label clinical study to explore how a peel-off facial mask containing myoinositol and trehalose-loaded liposomes could improve adult female acne (AFA). By applying the mask every other day for 60 days, we examined its effects on acne lesions, sebum production, and overall skin health.
During the study, we measured changes in the number of acne lesions and collected skin biopsy samples to analyze hormone levels and markers of autophagy—a process that helps the skin repair and rejuvenate itself. Our findings showed a significant reduction in various types of acne lesions, as well as a decrease in sebum production.
Notably, we observed a decrease in androgen levels in the skin, which is crucial since higher androgens can exacerbate acne. Additionally, levels of beclin-1, a marker associated with skin autophagy, increased, suggesting that the mask not only improved the appearance of acne but also encouraged healthier skin processes.
Overall, the peel-off mask with myoinositol effectively addresses some underlying factors contributing to acne in women, providing a promising option for those struggling with adult acne.
During the study, we measured changes in the number of acne lesions and collected skin biopsy samples to analyze hormone levels and markers of autophagy—a process that helps the skin repair and rejuvenate itself. Our findings showed a significant reduction in various types of acne lesions, as well as a decrease in sebum production.
Notably, we observed a decrease in androgen levels in the skin, which is crucial since higher androgens can exacerbate acne. Additionally, levels of beclin-1, a marker associated with skin autophagy, increased, suggesting that the mask not only improved the appearance of acne but also encouraged healthier skin processes.
Overall, the peel-off mask with myoinositol effectively addresses some underlying factors contributing to acne in women, providing a promising option for those struggling with adult acne.
Read More
9
We explored the effectiveness of Tracnil™, a treatment that combines myo-inositol, folic acid, and vitamin D3, in managing acne for overweight women of menstruation age who display signs of polycystic ovary syndrome (PCOS). While these women had normal hormone levels, many experienced acne along with other symptoms like hirsutism and irregular menstrual cycles.
During our study, we assessed acne improvement through visible lesion counts and evaluated hirsutism using standardized scales. What we found was encouraging—Tracnil™ significantly reduced both inflammatory and non-inflammatory acne lesions within just eight weeks. Furthermore, we observed improvements in hirsutism and the regularization of menstrual cycles among the participants.
It’s worth noting that the treatment didn’t lead to major side effects, indicating that it is safe to use. While we cannot isolate the exact effect of inositol from the overall treatment, it appears to play a key role in modulating skin symptoms in this population, even without significant hormonal imbalances. We believe Tracnil™ could be a first-line option for addressing acne in women with PCOS in a straightforward, practical manner within a dermatologist's office.
During our study, we assessed acne improvement through visible lesion counts and evaluated hirsutism using standardized scales. What we found was encouraging—Tracnil™ significantly reduced both inflammatory and non-inflammatory acne lesions within just eight weeks. Furthermore, we observed improvements in hirsutism and the regularization of menstrual cycles among the participants.
It’s worth noting that the treatment didn’t lead to major side effects, indicating that it is safe to use. While we cannot isolate the exact effect of inositol from the overall treatment, it appears to play a key role in modulating skin symptoms in this population, even without significant hormonal imbalances. We believe Tracnil™ could be a first-line option for addressing acne in women with PCOS in a straightforward, practical manner within a dermatologist's office.
Read More
9
We explored the effects of myo-inositol (MYO) on acne among young women diagnosed with polycystic ovary syndrome (PCOS). The study included 50 participants who underwent treatment with MYO for six months, focusing on its potential to improve the often frustrating skin issues linked to PCOS.
At the beginning and after the treatment period, we measured various factors including levels of hormones and insulin, as well as the severity of acne.
Remarkably, after three months of MYO therapy, we observed significant reductions in hormone levels associated with PCOS, particularly testosterone and insulin. After six months, both hirsutism and acne symptoms showed notable improvement among the participants.
This research highlights MYO as a promising, safe treatment option for alleviating acne symptoms in individuals with PCOS. Its ability to improve metabolic conditions while managing acne is a fascinating development for women seeking effective solutions for their skin concerns.
At the beginning and after the treatment period, we measured various factors including levels of hormones and insulin, as well as the severity of acne.
Remarkably, after three months of MYO therapy, we observed significant reductions in hormone levels associated with PCOS, particularly testosterone and insulin. After six months, both hirsutism and acne symptoms showed notable improvement among the participants.
This research highlights MYO as a promising, safe treatment option for alleviating acne symptoms in individuals with PCOS. Its ability to improve metabolic conditions while managing acne is a fascinating development for women seeking effective solutions for their skin concerns.
Read More
We embarked on a study to examine the effectiveness of inositol when used alongside metformin for women struggling with acne related to polycystic ovary syndrome (PCOS). Our research involved a randomized trial with two groups: one group received metformin alone, while the other combined metformin with myoinositol and D-chiro-inositol over a six-month period.
After analyzing the results, we observed that the group receiving the combined treatment showed a statistically significant improvement in their acne scores. Notably, the group taking both metformin and inositol experienced better skin outcomes compared to the group on metformin alone. Furthermore, additional metabolic and hormonal improvements were noted in this combined therapy group as well.
However, it’s essential to point out that our study did not isolate the effects of inositol alone on acne. So, while the combination showed promise for improving acne among women with PCOS, we're not claiming that inositol on its own is a guaranteed solution. Further research with a larger sample size and a focus on inositol's individual impact will be crucial for confirming these findings.
After analyzing the results, we observed that the group receiving the combined treatment showed a statistically significant improvement in their acne scores. Notably, the group taking both metformin and inositol experienced better skin outcomes compared to the group on metformin alone. Furthermore, additional metabolic and hormonal improvements were noted in this combined therapy group as well.
However, it’s essential to point out that our study did not isolate the effects of inositol alone on acne. So, while the combination showed promise for improving acne among women with PCOS, we're not claiming that inositol on its own is a guaranteed solution. Further research with a larger sample size and a focus on inositol's individual impact will be crucial for confirming these findings.
Read More
8
Inositol aids acne treatment efficacy
This study aimed to explore the effects of a combination therapy that includes myo-inositol, D-chiro-inositol, and other agents on acne in women with polycystic ovary syndrome (PCOS). Over a 12-week period, we observed significant improvements in acne symptoms not only in obese women but also in those who are lean.
The combination therapy also involved antioxidants and vitamins, creating a holistic approach to managing PCOS. While the focus was on the overall benefits for menstrual health and body weight, the positive effects on acne were quite notable.
Our findings suggest that those suffering from acne due to PCOS may benefit from including inositol in their treatment plan. This study reinforces the idea that a multi-faceted approach to PCOS management can lead to better outcomes in various symptoms, including skin issues like acne.
The combination therapy also involved antioxidants and vitamins, creating a holistic approach to managing PCOS. While the focus was on the overall benefits for menstrual health and body weight, the positive effects on acne were quite notable.
Our findings suggest that those suffering from acne due to PCOS may benefit from including inositol in their treatment plan. This study reinforces the idea that a multi-faceted approach to PCOS management can lead to better outcomes in various symptoms, including skin issues like acne.
Read More
User Reviews
USERS' SCORE
Moderately Good
Based on 16 Reviews
7
- All Reviews
- Positive Reviews
- Negative Reviews
9
Period regularity
16 people found this helpful
For those suffering from polycystic ovaries, I highly recommend this treatment. After two months, my periods returned, chronic pain disappeared, and my acne has improved significantly. Using a higher dosage is more effective; I take two to three tablets daily.
Read More
9
Acne improvement
3 people found this helpful
This product has greatly improved my facial acne and regulates my insulin levels, much more effectively than glucophage for cysts. I take it after meals, one or two pills, and the results are remarkable without needing a diet.
Read More
9
Cognitive support
1 people found this helpful
I take this daily and have noticed benefits such as improved cognitive function and a reduction in my acne. It feels perfect to have both elements combined in one capsule.
Read More
9
No side effects
1 people found this helpful
Inositol has been remarkably effective for my severe acne and irregular menstruation due to PCOS. Unlike birth control pills that caused side effects, inositol is well-tolerated without any noticeable drawbacks.
Read More
9
Cycle stabilised
1 people found this helpful
I recommend inositol as a supplement for PCOS. It has helped restore my menstrual cycle, which is now consistently 28-30 days, and my acne has disappeared. I'm grateful for the positive impact inositol has made!
Read More
Frequently Asked Questions
9
Period regularity
16 people found this helpful
For those suffering from polycystic ovaries, I highly recommend this treatment. After two months, my periods returned, chronic pain disappeared, and my acne has improved significantly. Using a higher dosage is more effective; I take two to three tablets daily.
7.5
Energy levels improved
I have been taking this for my PCOS for two months and noticed improved energy levels. My acne has reduced, although I experience vivid dreams if I take it close to bedtime.
7.5
Regular use
4 people found this helpful
I started taking this at least six months ago for my polycystic ovaries, and it has effectively helped with my adult acne and menstrual cycle. I consistently take it daily, even after indulgent meals, and it's become essential for my health.
2
Limited effect on acne
I purchased it due to my chin acne and took it for around two months. Unfortunately, I haven't noticed much of an effect. What should I do about the acne on my chin?
9
Acne improvement
3 people found this helpful
This product has greatly improved my facial acne and regulates my insulin levels, much more effectively than glucophage for cysts. I take it after meals, one or two pills, and the results are remarkable without needing a diet.
6
Improved acne condition
1 people found this helpful
I purchased it after reading that it helps with adult acne. I've been taking 2 tablets daily and have noticed an improvement in my acne, although I'm unsure if it's due to choline inositol or my new exfoliation routine. However, I experienced a month-long delay in my period, which made me anxious. After researching, I found many others had similar experiences. I've dealt with endometriosis and will continue using it.
6
Cyst treatment
57 people found this helpful
I had been using contraceptive pills for over ten years to manage my acne and for protection. After stopping them to conceive, acne reappeared, along with complications from a ruptured cyst. My gynecologist recommended inositol and folic acid. Although acne flared initially, it has become less severe and heals quicker. I’ve noticed improvements while taking inositol powder regularly.
0
Weight reduction
9 people found this helpful
I bought this after discovering its ability to help with adult acne. I take two tablets daily, and my acne has improved. I'm concerned about delayed menstruation, but I plan to continue taking it due to my endometriosis condition.
We embarked on a study to examine the effectiveness of inositol when used alongside metformin for women struggling with acne related to polycystic ovary syndrome (PCOS). Our research involved a randomized trial with two groups: one group received metformin alone, while the other combined metformin with myoinositol and D-chiro-inositol over a six-month period.
After analyzing the results, we observed that the group receiving the combined treatment showed a statistically significant improvement in their acne scores. Notably, the group taking both metformin and inositol experienced better skin outcomes compared to the group on metformin alone. Furthermore, additional metabolic and hormonal improvements were noted in this combined therapy group as well.
However, it’s essential to point out that our study did not isolate the effects of inositol alone on acne. So, while the combination showed promise for improving acne among women with PCOS, we're not claiming that inositol on its own is a guaranteed solution. Further research with a larger sample size and a focus on inositol's individual impact will be crucial for confirming these findings.
After analyzing the results, we observed that the group receiving the combined treatment showed a statistically significant improvement in their acne scores. Notably, the group taking both metformin and inositol experienced better skin outcomes compared to the group on metformin alone. Furthermore, additional metabolic and hormonal improvements were noted in this combined therapy group as well.
However, it’s essential to point out that our study did not isolate the effects of inositol alone on acne. So, while the combination showed promise for improving acne among women with PCOS, we're not claiming that inositol on its own is a guaranteed solution. Further research with a larger sample size and a focus on inositol's individual impact will be crucial for confirming these findings.
9
We explored the effectiveness of Tracnil™, a treatment that combines myo-inositol, folic acid, and vitamin D3, in managing acne for overweight women of menstruation age who display signs of polycystic ovary syndrome (PCOS). While these women had normal hormone levels, many experienced acne along with other symptoms like hirsutism and irregular menstrual cycles.
During our study, we assessed acne improvement through visible lesion counts and evaluated hirsutism using standardized scales. What we found was encouraging—Tracnil™ significantly reduced both inflammatory and non-inflammatory acne lesions within just eight weeks. Furthermore, we observed improvements in hirsutism and the regularization of menstrual cycles among the participants.
It’s worth noting that the treatment didn’t lead to major side effects, indicating that it is safe to use. While we cannot isolate the exact effect of inositol from the overall treatment, it appears to play a key role in modulating skin symptoms in this population, even without significant hormonal imbalances. We believe Tracnil™ could be a first-line option for addressing acne in women with PCOS in a straightforward, practical manner within a dermatologist's office.
During our study, we assessed acne improvement through visible lesion counts and evaluated hirsutism using standardized scales. What we found was encouraging—Tracnil™ significantly reduced both inflammatory and non-inflammatory acne lesions within just eight weeks. Furthermore, we observed improvements in hirsutism and the regularization of menstrual cycles among the participants.
It’s worth noting that the treatment didn’t lead to major side effects, indicating that it is safe to use. While we cannot isolate the exact effect of inositol from the overall treatment, it appears to play a key role in modulating skin symptoms in this population, even without significant hormonal imbalances. We believe Tracnil™ could be a first-line option for addressing acne in women with PCOS in a straightforward, practical manner within a dermatologist's office.
8
Inositol aids acne treatment efficacy
This study aimed to explore the effects of a combination therapy that includes myo-inositol, D-chiro-inositol, and other agents on acne in women with polycystic ovary syndrome (PCOS). Over a 12-week period, we observed significant improvements in acne symptoms not only in obese women but also in those who are lean.
The combination therapy also involved antioxidants and vitamins, creating a holistic approach to managing PCOS. While the focus was on the overall benefits for menstrual health and body weight, the positive effects on acne were quite notable.
Our findings suggest that those suffering from acne due to PCOS may benefit from including inositol in their treatment plan. This study reinforces the idea that a multi-faceted approach to PCOS management can lead to better outcomes in various symptoms, including skin issues like acne.
The combination therapy also involved antioxidants and vitamins, creating a holistic approach to managing PCOS. While the focus was on the overall benefits for menstrual health and body weight, the positive effects on acne were quite notable.
Our findings suggest that those suffering from acne due to PCOS may benefit from including inositol in their treatment plan. This study reinforces the idea that a multi-faceted approach to PCOS management can lead to better outcomes in various symptoms, including skin issues like acne.
9
We explored the effects of myo-inositol (MYO) on acne among young women diagnosed with polycystic ovary syndrome (PCOS). The study included 50 participants who underwent treatment with MYO for six months, focusing on its potential to improve the often frustrating skin issues linked to PCOS.
At the beginning and after the treatment period, we measured various factors including levels of hormones and insulin, as well as the severity of acne.
Remarkably, after three months of MYO therapy, we observed significant reductions in hormone levels associated with PCOS, particularly testosterone and insulin. After six months, both hirsutism and acne symptoms showed notable improvement among the participants.
This research highlights MYO as a promising, safe treatment option for alleviating acne symptoms in individuals with PCOS. Its ability to improve metabolic conditions while managing acne is a fascinating development for women seeking effective solutions for their skin concerns.
At the beginning and after the treatment period, we measured various factors including levels of hormones and insulin, as well as the severity of acne.
Remarkably, after three months of MYO therapy, we observed significant reductions in hormone levels associated with PCOS, particularly testosterone and insulin. After six months, both hirsutism and acne symptoms showed notable improvement among the participants.
This research highlights MYO as a promising, safe treatment option for alleviating acne symptoms in individuals with PCOS. Its ability to improve metabolic conditions while managing acne is a fascinating development for women seeking effective solutions for their skin concerns.
References
- Bahadur A, Arora H, Ravi AK, Naithani M, Bahurupi Y, et al. Comparison of Clinical, Metabolic and Hormonal Effects of Metformin Versus Combined Therapy of Metformin With Myoinositol Plus D-Chiro-Inositol in Women With Polycystic Ovary Syndrome (PCOS): A Randomized Controlled Trial. Cureus. 2021;13:e15510. doi:10.7759/cureus.15510
- Ramanan EA, Ravi S, Anbu KRR, Michael M. Efficacy and Safety of Tracnil™ Administration in Patients with Dermatological Manifestations of PCOS: An Open-Label Single-Arm Study. Dermatol Res Pract. 2020;2020:7019126. doi:10.1155/2020/7019126
- Advani K, Batra M, Tajpuriya S, Gupta R, Saraswat A, et al. Efficacy of combination therapy of inositols, antioxidants and vitamins in obese and non-obese women with polycystic ovary syndrome: an observational study. J Obstet Gynaecol. 2020;40:96. doi:10.1080/01443615.2019.1604644
- Tolino E, Skroza N, Mambrin A, Bernardini N, Zuber S, et al. Novel combination for the treatment of acne differentiated based on gender: a new step towards personalized treatment. G Ital Dermatol Venereol. 2018;153:866. doi:10.23736/S0392-0488.18.05710-3
- Fabbrocini G, Capasso C, Donnarumma M, Cantelli M, Le Maître M, et al. A peel-off facial mask comprising myoinositol and trehalose-loaded liposomes improves adult female acne by reducing local hyperandrogenism and activating autophagy. J Cosmet Dermatol. 2017;16:480. doi:10.1111/jocd.12340
- Formuso C, Stracquadanio M, Ciotta L. Myo-inositol vs. D-chiro inositol in PCOS treatment. Minerva Ginecol. 2015;67:321.
- Zacchè MM, Caputo L, Filippis S, Zacchè G, Dindelli M, et al. Efficacy of myo-inositol in the treatment of cutaneous disorders in young women with polycystic ovary syndrome. Gynecol Endocrinol. 2009;25:508. doi:10.1080/09513590903015544
- Pezza M, Carlomagno V, Sammarco E, Trischitta A, Ceddia C, et al. Association of Myo-Inositol and Microlipodispersed Magnesium in Androgen-Dependent Dermatological Diseases: A Retrospective Study. Pharmaceuticals (Basel). 2025;18. doi:10.3390/ph18020251
