Reviewed By
Reviewed By
Overview
SCIENTIFIC SCORE
Moderately Effective
Based on 1 Research
8
USERS' SCORE
Good
Based on 7 Reviews
8.5
Supplement Facts
Serving Size: 1 Veg Capsule
Amount Per Serving
%DV
Choline (from 630 mg Choline Bitartrate)
250 mg
45%
Inositol
250 mg
â€
Top Medical Research Studies
8
We sought to understand how inositol polyphosphate-5-phosphatase K influences the recovery of axons in the context of stroke and other central nervous system (CNS) injuries. By studying intact corticospinal neurons from mice that had experienced a pyramidotomy, we found that this protein plays a crucial role in facilitating axon growth.
Our exploration involved various preclinical models and established that overexpressing inositol polyphosphate-5-phosphatase K in these neurons enhanced the sprouting of corticospinal tract terminals after a stroke, demonstrating promising effects not just after immediate injury but also in instances of chronic damage.
We observed that this enhancement occurs partly through the elevation of active cofilin within the growth cones of neurons, which catalyzes critical processes for maintaining healthy axon structures and supports the potential for neurological recovery post-stroke. The results indicate that inositol could be a significant factor in encouraging damaged CNS neurons to regrow axons, a key aspect of functional recovery following injuries like stroke or spinal cord trauma.
Ultimately, our findings reinforce the value of pursuing new strategies to boost axon growth in complex environments where traditional healing has been limited, showcasing the necessity of continued research into factors that promote nerve regeneration.
Our exploration involved various preclinical models and established that overexpressing inositol polyphosphate-5-phosphatase K in these neurons enhanced the sprouting of corticospinal tract terminals after a stroke, demonstrating promising effects not just after immediate injury but also in instances of chronic damage.
We observed that this enhancement occurs partly through the elevation of active cofilin within the growth cones of neurons, which catalyzes critical processes for maintaining healthy axon structures and supports the potential for neurological recovery post-stroke. The results indicate that inositol could be a significant factor in encouraging damaged CNS neurons to regrow axons, a key aspect of functional recovery following injuries like stroke or spinal cord trauma.
Ultimately, our findings reinforce the value of pursuing new strategies to boost axon growth in complex environments where traditional healing has been limited, showcasing the necessity of continued research into factors that promote nerve regeneration.
Read More
Most Useful Reviews
9
Supports recovery
10 people found this helpful
It was instrumental in my father’s recovery following a stroke. He recovered satisfactorily from the effects of the stroke and the resulting physical weakness.
Read More
9
Overcomes stroke effect
4 people found this helpful
Protect your brain! This nutrient is vital; it addresses the Choline deficiency often lacking in our normal diet. My premature daughter overcame a stroke at birth, thanks to her mother’s supplementation with Choline and Inositol prior to and during the first trimester. This underscores the importance of such nutrients.
Read More
9
Restores brain cells
Excellent đź‘Ť It restores brain cells after a stroke, dementia, and Alzheimer's, while also enhancing memory. I highly recommend it.
Read More
Medical Researches
SCIENTIFIC SCORE
Moderately Effective
Based on 1 Research
8
- All Researches
8
We sought to understand how inositol polyphosphate-5-phosphatase K influences the recovery of axons in the context of stroke and other central nervous system (CNS) injuries. By studying intact corticospinal neurons from mice that had experienced a pyramidotomy, we found that this protein plays a crucial role in facilitating axon growth.
Our exploration involved various preclinical models and established that overexpressing inositol polyphosphate-5-phosphatase K in these neurons enhanced the sprouting of corticospinal tract terminals after a stroke, demonstrating promising effects not just after immediate injury but also in instances of chronic damage.
We observed that this enhancement occurs partly through the elevation of active cofilin within the growth cones of neurons, which catalyzes critical processes for maintaining healthy axon structures and supports the potential for neurological recovery post-stroke. The results indicate that inositol could be a significant factor in encouraging damaged CNS neurons to regrow axons, a key aspect of functional recovery following injuries like stroke or spinal cord trauma.
Ultimately, our findings reinforce the value of pursuing new strategies to boost axon growth in complex environments where traditional healing has been limited, showcasing the necessity of continued research into factors that promote nerve regeneration.
Our exploration involved various preclinical models and established that overexpressing inositol polyphosphate-5-phosphatase K in these neurons enhanced the sprouting of corticospinal tract terminals after a stroke, demonstrating promising effects not just after immediate injury but also in instances of chronic damage.
We observed that this enhancement occurs partly through the elevation of active cofilin within the growth cones of neurons, which catalyzes critical processes for maintaining healthy axon structures and supports the potential for neurological recovery post-stroke. The results indicate that inositol could be a significant factor in encouraging damaged CNS neurons to regrow axons, a key aspect of functional recovery following injuries like stroke or spinal cord trauma.
Ultimately, our findings reinforce the value of pursuing new strategies to boost axon growth in complex environments where traditional healing has been limited, showcasing the necessity of continued research into factors that promote nerve regeneration.
Read More
User Reviews
USERS' SCORE
Good
Based on 7 Reviews
8.5
- All Reviews
- Positive Reviews
- Negative Reviews
9
Supports recovery
10 people found this helpful
It was instrumental in my father’s recovery following a stroke. He recovered satisfactorily from the effects of the stroke and the resulting physical weakness.
Read More
9
Overcomes stroke effect
4 people found this helpful
Protect your brain! This nutrient is vital; it addresses the Choline deficiency often lacking in our normal diet. My premature daughter overcame a stroke at birth, thanks to her mother’s supplementation with Choline and Inositol prior to and during the first trimester. This underscores the importance of such nutrients.
Read More
9
Restores brain cells
Excellent đź‘Ť It restores brain cells after a stroke, dementia, and Alzheimer's, while also enhancing memory. I highly recommend it.
Read More
9
Regular support
Recommended by a doctor after a stroke, we buy it regularly for support, and I find it very effective.
Read More
7.5
Better results
I substituted gliatilin with this for an elderly person after strokes and the results are noticeably better, proving to be more economical as well.
Read More
Frequently Asked Questions
9
Supports recovery
10 people found this helpful
It was instrumental in my father’s recovery following a stroke. He recovered satisfactorily from the effects of the stroke and the resulting physical weakness.
9
Overcomes stroke effect
4 people found this helpful
Protect your brain! This nutrient is vital; it addresses the Choline deficiency often lacking in our normal diet. My premature daughter overcame a stroke at birth, thanks to her mother’s supplementation with Choline and Inositol prior to and during the first trimester. This underscores the importance of such nutrients.
6
Improves health
I purchased it for my mother after her stroke to improve her cognitive function and act as a tonic for her overall health. While it’s hard to pinpoint the results due to the numerous treatments she undertook, her health state seemed to normalise.
7.5
Better results
I substituted gliatilin with this for an elderly person after strokes and the results are noticeably better, proving to be more economical as well.
7.5
Advised by doctor
2 people found this helpful
Excellent! I ordered this for my parents post-stroke and cerebral infarction, based on the doctor's advice to take it alongside medication: B-50 in the morning and an amino acid complex with choline and inositol at lunch.
9
Regular support
Recommended by a doctor after a stroke, we buy it regularly for support, and I find it very effective.
8
We sought to understand how inositol polyphosphate-5-phosphatase K influences the recovery of axons in the context of stroke and other central nervous system (CNS) injuries. By studying intact corticospinal neurons from mice that had experienced a pyramidotomy, we found that this protein plays a crucial role in facilitating axon growth.
Our exploration involved various preclinical models and established that overexpressing inositol polyphosphate-5-phosphatase K in these neurons enhanced the sprouting of corticospinal tract terminals after a stroke, demonstrating promising effects not just after immediate injury but also in instances of chronic damage.
We observed that this enhancement occurs partly through the elevation of active cofilin within the growth cones of neurons, which catalyzes critical processes for maintaining healthy axon structures and supports the potential for neurological recovery post-stroke. The results indicate that inositol could be a significant factor in encouraging damaged CNS neurons to regrow axons, a key aspect of functional recovery following injuries like stroke or spinal cord trauma.
Ultimately, our findings reinforce the value of pursuing new strategies to boost axon growth in complex environments where traditional healing has been limited, showcasing the necessity of continued research into factors that promote nerve regeneration.
Our exploration involved various preclinical models and established that overexpressing inositol polyphosphate-5-phosphatase K in these neurons enhanced the sprouting of corticospinal tract terminals after a stroke, demonstrating promising effects not just after immediate injury but also in instances of chronic damage.
We observed that this enhancement occurs partly through the elevation of active cofilin within the growth cones of neurons, which catalyzes critical processes for maintaining healthy axon structures and supports the potential for neurological recovery post-stroke. The results indicate that inositol could be a significant factor in encouraging damaged CNS neurons to regrow axons, a key aspect of functional recovery following injuries like stroke or spinal cord trauma.
Ultimately, our findings reinforce the value of pursuing new strategies to boost axon growth in complex environments where traditional healing has been limited, showcasing the necessity of continued research into factors that promote nerve regeneration.
References
- Kauer SD, Fink KL, Li EHF, Evans BP, Golan N, et al. Inositol Polyphosphate-5-Phosphatase K () Enhances Sprouting of Corticospinal Tract Axons after CNS Trauma. J Neurosci. 2022;42:2190. 10.1523/JNEUROSCI.0897-21.2022
