Overview
SCIENTIFIC SCORE
Moderately Effective
Based on 16 Researches
8.7
USERS' SCORE
Good
Based on 32 Reviews
8
Supplement Facts
Serving Size: 1 Veg Capsule
Amount Per Serving
%DV
Curcumin Phytosome(Turmeric Rhizome Extract (curcuma longa)/Phosphatidyl Choline Complex) (Meriva® Turmeric Phytosome)(Standardized to min. 18% Curcuminoids - 90 mg)
500 mg
**
Top Medical Research Studies
9
In a well-structured study involving 101 adults suffering from knee osteoarthritis, we explored the effects of curcumin, a compound derived from turmeric, on knee pain. Participants were randomly assigned to receive either 500 mg of a standardized curcumin extract, Curcugen, twice daily, or a placebo for eight weeks, allowing for a clear comparison of its effectiveness.
Our findings revealed promising results. Curcumin significantly reduced knee pain scores and overall pain ratings compared to the placebo. We also noticed that participants taking curcumin showed greater improvements in various physical tests, like the timed up-and-go and six-minute walk tests, indicating enhanced mobility.
Interestingly, 37% of those on curcumin reduced their pain medications, which highlights the potential for curcumin to provide relief and improve quality of life for those with this condition. While the study didn’t explore longer treatment durations or different dosages, these initial results support curcumin's role as a feasible option for managing osteoarthritis pain in the knee.
Our findings revealed promising results. Curcumin significantly reduced knee pain scores and overall pain ratings compared to the placebo. We also noticed that participants taking curcumin showed greater improvements in various physical tests, like the timed up-and-go and six-minute walk tests, indicating enhanced mobility.
Interestingly, 37% of those on curcumin reduced their pain medications, which highlights the potential for curcumin to provide relief and improve quality of life for those with this condition. While the study didn’t explore longer treatment durations or different dosages, these initial results support curcumin's role as a feasible option for managing osteoarthritis pain in the knee.
Read More
9
We sought to determine the effectiveness of Curcuma longa extract, commonly known as turmeric, in alleviating knee pain associated with osteoarthritis. Our investigation focused on randomized controlled trials that compared turmeric extract with placebo, analyzing data from notable databases like PubMed and Cochrane Library through April 2021.
In total, we reviewed 10 trials encompassing 783 patients. The outcomes of our analysis were quite promising. We found that patients taking Curcuma longa experienced significantly greater relief from pain and improved overall function compared to those given a placebo. Notably, the measures used to assess pain and functionality showed results that exceeded the minimum clinically important differences, meaning that the improvements were not just statistically significant but also meaningful in real life.
This evidence suggests that incorporating turmeric extract into treatment plans may offer substantial benefits for those suffering from knee osteoarthritis. However, we must acknowledge that the studies we reviewed exhibited some variability, indicating a need for further high-quality research with larger participant groups to corroborate our findings on turmeric’s effectiveness.
In total, we reviewed 10 trials encompassing 783 patients. The outcomes of our analysis were quite promising. We found that patients taking Curcuma longa experienced significantly greater relief from pain and improved overall function compared to those given a placebo. Notably, the measures used to assess pain and functionality showed results that exceeded the minimum clinically important differences, meaning that the improvements were not just statistically significant but also meaningful in real life.
This evidence suggests that incorporating turmeric extract into treatment plans may offer substantial benefits for those suffering from knee osteoarthritis. However, we must acknowledge that the studies we reviewed exhibited some variability, indicating a need for further high-quality research with larger participant groups to corroborate our findings on turmeric’s effectiveness.
Read More
9.5
We aimed to understand how curcumin, a compound found in turmeric, impacts knee pain in individuals suffering from osteoarthritis (OA). Using various databases, we gathered and analyzed data from multiple meta-analyses that included randomized controlled trials focused on curcumin's effects on OA symptoms up to September 2023.
The results clearly demonstrated that curcumin supplementation substantially alleviates pain, as reflected in reduced scores on several pain measurement scales. These included the visual analog scale (VAS) and the Western Ontario and McMaster Universities Arthritis Index (WOMAC) for pain, function, and stiffness.
Statistically significant improvements were observed across the board, highlighting that curcumin not only helps in reducing pain but also enhances joint function and decreases stiffness. This collectively suggests that curcumin can be an effective supplement for those managing knee OA, possibly minimizing the need for other medications.
Overall, our findings support the benefits of incorporating curcumin into treatment plans for osteoarthritis, offering a promising path for pain relief and improved mobility.
The results clearly demonstrated that curcumin supplementation substantially alleviates pain, as reflected in reduced scores on several pain measurement scales. These included the visual analog scale (VAS) and the Western Ontario and McMaster Universities Arthritis Index (WOMAC) for pain, function, and stiffness.
Statistically significant improvements were observed across the board, highlighting that curcumin not only helps in reducing pain but also enhances joint function and decreases stiffness. This collectively suggests that curcumin can be an effective supplement for those managing knee OA, possibly minimizing the need for other medications.
Overall, our findings support the benefits of incorporating curcumin into treatment plans for osteoarthritis, offering a promising path for pain relief and improved mobility.
Read More
Most Useful Reviews
9
Significant pain relief
37 people found this helpful
Curcumin has greatly improved my rheumatoid arthritis symptoms in my wrists, knees, and back. I no longer rely on painkillers, and I feel near pain-free. This supplement energises me, but I advise exercising with caution to avoid overdoing it. iHerb offers great prices and fresh products.
Read More
7.5
Effective inflammation reduction
15 people found this helpful
This curcumin form is highly bioavailable and has significantly decreased my knee pain and inflammation. I've also noticed improvements during colds. I often add the powder to cosmetic masks due to its excellent quality. Highly recommend it!
Read More
9
Unexpectedly effective
9 people found this helpful
I didn't expect this supplement to work so quickly, but after two days, my knee pain decreased. I also felt an increase in energy and mood. It's now a staple in my routine, taken twice daily with meals.
Read More
Medical Researches
SCIENTIFIC SCORE
Moderately Effective
Based on 16 Researches
8.7
- All Researches
9.5
We aimed to understand how curcumin, a compound found in turmeric, impacts knee pain in individuals suffering from osteoarthritis (OA). Using various databases, we gathered and analyzed data from multiple meta-analyses that included randomized controlled trials focused on curcumin's effects on OA symptoms up to September 2023.
The results clearly demonstrated that curcumin supplementation substantially alleviates pain, as reflected in reduced scores on several pain measurement scales. These included the visual analog scale (VAS) and the Western Ontario and McMaster Universities Arthritis Index (WOMAC) for pain, function, and stiffness.
Statistically significant improvements were observed across the board, highlighting that curcumin not only helps in reducing pain but also enhances joint function and decreases stiffness. This collectively suggests that curcumin can be an effective supplement for those managing knee OA, possibly minimizing the need for other medications.
Overall, our findings support the benefits of incorporating curcumin into treatment plans for osteoarthritis, offering a promising path for pain relief and improved mobility.
The results clearly demonstrated that curcumin supplementation substantially alleviates pain, as reflected in reduced scores on several pain measurement scales. These included the visual analog scale (VAS) and the Western Ontario and McMaster Universities Arthritis Index (WOMAC) for pain, function, and stiffness.
Statistically significant improvements were observed across the board, highlighting that curcumin not only helps in reducing pain but also enhances joint function and decreases stiffness. This collectively suggests that curcumin can be an effective supplement for those managing knee OA, possibly minimizing the need for other medications.
Overall, our findings support the benefits of incorporating curcumin into treatment plans for osteoarthritis, offering a promising path for pain relief and improved mobility.
Read More
9
Topical curcumin gel effectiveness
We conducted a study to explore the effectiveness of a unique topical gel infused with curcumin, a key ingredient in turmeric, for treating knee osteoarthritis. This innovative gel utilizes a self-nano-emulsifying organogel system, which allows for better delivery of curcumin, a compound known for its challenging solubility and stability issues.
In our research, we utilized a double-blind clinical trial design to assess the outcomes of participants using the gel compared to those receiving a placebo over an eight-week period. The results were promising; those applying the gel experienced significant reductions in pain, stiffness, and physical function difficulties. Specifically, pain scores improved by 71.68% compared to only 7.03% in the placebo group.
Overall, this study highlights the potential of using curcumin in a new topical treatment that addresses knee pain effectively. While the gel specifically utilizes curcumin, it offers an alternative approach that leverages the benefits of turmeric without relying directly on the spice itself.
In our research, we utilized a double-blind clinical trial design to assess the outcomes of participants using the gel compared to those receiving a placebo over an eight-week period. The results were promising; those applying the gel experienced significant reductions in pain, stiffness, and physical function difficulties. Specifically, pain scores improved by 71.68% compared to only 7.03% in the placebo group.
Overall, this study highlights the potential of using curcumin in a new topical treatment that addresses knee pain effectively. While the gel specifically utilizes curcumin, it offers an alternative approach that leverages the benefits of turmeric without relying directly on the spice itself.
Read More
9
Turmeric improves knee osteoarthritis
Our study focused on the impact of a specific combination of polyphenolic supplements, including turmeric, on knee pain for individuals with osteoarthritis. We conducted a randomized controlled trial with 60 participants, half of whom received the polyphenolic supplement featuring turmeric, rosemary extract, and resveratrol, while the other half received a placebo.
Over the course of 12 weeks, those taking the polyphenol supplement reported significantly reduced pain levels and improved physical functionality. The data was collected using validated questionnaires, demonstrating clearer benefits in this group compared to those on the placebo.
Notably, we observed that the polyphenol supplement also helped reduce systemic inflammation, which could be a key factor in easing knee pain. This suggests that turmeric, as part of the supplement, may play a beneficial role in managing not just pain, but also the overall quality of life for those suffering from knee osteoarthritis.
Over the course of 12 weeks, those taking the polyphenol supplement reported significantly reduced pain levels and improved physical functionality. The data was collected using validated questionnaires, demonstrating clearer benefits in this group compared to those on the placebo.
Notably, we observed that the polyphenol supplement also helped reduce systemic inflammation, which could be a key factor in easing knee pain. This suggests that turmeric, as part of the supplement, may play a beneficial role in managing not just pain, but also the overall quality of life for those suffering from knee osteoarthritis.
Read More
9
We studied the effects of curcumin, a compound in turmeric, alongside swimming to see how this combination could help alleviate knee pain caused by osteoarthritis (OA). In our research with rats, we set up five groups, with some getting the treatment and others serving as a control.
After injecting a substance that induces OA, we began a daily swimming regimen for certain groups and provided them with oral curcumin over four weeks. This combination proved to be the most effective in reducing pain and stiffness in the joints.
Not only did we notice improvement in the rats' discomfort, but there were also positive changes seen in their joint health when examined under a microscope. We observed a decrease in markers of inflammation, suggesting that the dual treatment could provide a more effective path for managing knee pain in osteoarthritis patients.
Overall, this research highlights the potential benefits of combining curcumin with physical activity like swimming for easing knee pain due to OA.
After injecting a substance that induces OA, we began a daily swimming regimen for certain groups and provided them with oral curcumin over four weeks. This combination proved to be the most effective in reducing pain and stiffness in the joints.
Not only did we notice improvement in the rats' discomfort, but there were also positive changes seen in their joint health when examined under a microscope. We observed a decrease in markers of inflammation, suggesting that the dual treatment could provide a more effective path for managing knee pain in osteoarthritis patients.
Overall, this research highlights the potential benefits of combining curcumin with physical activity like swimming for easing knee pain due to OA.
Read More
9
In our analysis, we investigated how a blend of several natural ingredients, including turmeric (CurQlife, curcumin), might alleviate knee pain in individuals suffering from osteoarthritis. Our study focused on the effects of this combination of nutraceuticals, known as Clagen™, which also includes native type 2 collagen, hyaluronic acid, and other supportive components.
We enrolled 100 patients with knee osteoarthritis and monitored their progress over two months. At the end of this period, we noted a significant reduction in pain levels, as evidenced by improved Visual Analog Scale (VAS) scores. Additionally, there were noticeable enhancements in the range of motion and overall quality of life for the participants.
While turmeric was part of the combination, we can't isolate its specific effects from those of the other ingredients. Nonetheless, this study suggests that combining these natural substances may offer a beneficial strategy for managing knee pain, potentially reducing the need for traditional pain medications like NSAIDs in the long run. However, further long-term studies are needed to confirm these findings.
We enrolled 100 patients with knee osteoarthritis and monitored their progress over two months. At the end of this period, we noted a significant reduction in pain levels, as evidenced by improved Visual Analog Scale (VAS) scores. Additionally, there were noticeable enhancements in the range of motion and overall quality of life for the participants.
While turmeric was part of the combination, we can't isolate its specific effects from those of the other ingredients. Nonetheless, this study suggests that combining these natural substances may offer a beneficial strategy for managing knee pain, potentially reducing the need for traditional pain medications like NSAIDs in the long run. However, further long-term studies are needed to confirm these findings.
Read More
User Reviews
USERS' SCORE
Good
Based on 32 Reviews
8
- All Reviews
- Positive Reviews
- Negative Reviews
9
Significant pain relief
37 people found this helpful
Curcumin has greatly improved my rheumatoid arthritis symptoms in my wrists, knees, and back. I no longer rely on painkillers, and I feel near pain-free. This supplement energises me, but I advise exercising with caution to avoid overdoing it. iHerb offers great prices and fresh products.
Read More
7.5
Effective inflammation reduction
15 people found this helpful
This curcumin form is highly bioavailable and has significantly decreased my knee pain and inflammation. I've also noticed improvements during colds. I often add the powder to cosmetic masks due to its excellent quality. Highly recommend it!
Read More
9
Unexpectedly effective
9 people found this helpful
I didn't expect this supplement to work so quickly, but after two days, my knee pain decreased. I also felt an increase in energy and mood. It's now a staple in my routine, taken twice daily with meals.
Read More
9
Joint relief achieved
8 people found this helpful
Within a week, my lower back and creaky knees stopped making noise. Very impressed with this turmeric product!
Read More
9
Joint pain alleviated
7 people found this helpful
My knee pain has vanished! As an active 42-year-old, this product allows me to train harder without pain. It's made a significant difference in my recovery times. Thank you, iHerb!
Read More
Frequently Asked Questions
9
Unexpectedly effective
9 people found this helpful
I didn't expect this supplement to work so quickly, but after two days, my knee pain decreased. I also felt an increase in energy and mood. It's now a staple in my routine, taken twice daily with meals.
9
Knee pain improved
1 people found this helpful
Well! After a week, my knee pain vanished, so I bought two more bottles for elderly family members.
7.5
Joint pain improvement
4 people found this helpful
I bought these for my husband suffering from knee pain and arthritis. After a couple of weeks, he's pleased to report that the pain in all his joints has eased significantly.
9
Joint relief achieved
8 people found this helpful
Within a week, my lower back and creaky knees stopped making noise. Very impressed with this turmeric product!
9
Significant pain relief
37 people found this helpful
Curcumin has greatly improved my rheumatoid arthritis symptoms in my wrists, knees, and back. I no longer rely on painkillers, and I feel near pain-free. This supplement energises me, but I advise exercising with caution to avoid overdoing it. iHerb offers great prices and fresh products.
7.5
Life-changing supplement
5 people found this helpful
After months on anti-inflammatories for arthritis in my knees, curcumin has been life-changing. Although the pain isn't gone, it's manageable, and I can function normally. It's surprising that doctors don't recommend it more often!
7.5
Reduced knee pain
3 people found this helpful
Fine, I purchased this for my mother due to her knee problems on the advice of a nutritionist. It's best to take curcumin alongside glucosamine, chondroitin, and boswellia. I chose the phytosome form for its better absorption. Curcumin is an antioxidant with anti-inflammatory and analgesic properties. After starting it, her knee swelling and pain decreased. There is a benefit!
4
Long-term pain management
25 people found this helpful
Curcumin has reduced my knee pain, offering better long-term relief without liver damage. It blocks iron absorption, so I've adjusted my intake to ensure my iron levels remain stable. When I ran out, the pain returned, making this supplement essential for me.
8
We delved into how turmeric might help alleviate knee pain associated with osteoarthritis (OA), a condition affecting a significant number of adults. The study we reviewed was a comprehensive systematic review and meta-analysis involving a total of ten randomized controlled trials with 786 participants.
The main focus was on evaluating the impact of turmeric on pain relief, specifically through the Visual Analog Scale (VAS) for pain and the Western Ontario and McMaster Universities Arthritis Index (WOMAC) total score. Turmeric showed promise by significantly improving pain scores compared to a placebo and demonstrated effects comparable to those of nonsteroidal anti-inflammatory drugs (NSAIDs).
With results highlighting an improvement in pain levels, both lower and higher dosages of turmeric were effective when compared to placebo. However, we also noted that the limitations and variability in the studies suggest that further research would be beneficial to determine the best dosages and methods for using turmeric as a treatment option for knee OA.
Overall, the findings suggest that turmeric could be a valuable alternative for those seeking relief from knee pain due to osteoarthritis, standing out against standard options like NSAIDs while having a potentially fewer side effects.
The main focus was on evaluating the impact of turmeric on pain relief, specifically through the Visual Analog Scale (VAS) for pain and the Western Ontario and McMaster Universities Arthritis Index (WOMAC) total score. Turmeric showed promise by significantly improving pain scores compared to a placebo and demonstrated effects comparable to those of nonsteroidal anti-inflammatory drugs (NSAIDs).
With results highlighting an improvement in pain levels, both lower and higher dosages of turmeric were effective when compared to placebo. However, we also noted that the limitations and variability in the studies suggest that further research would be beneficial to determine the best dosages and methods for using turmeric as a treatment option for knee OA.
Overall, the findings suggest that turmeric could be a valuable alternative for those seeking relief from knee pain due to osteoarthritis, standing out against standard options like NSAIDs while having a potentially fewer side effects.
8
We investigated how curcumin, a compound found in turmeric, along with vitamin D, could affect knee pain and the progression of knee osteoarthritis (OA) in a specific rat model. In this study, male Wistar rats were divided into five groups: a control group, a group receiving curcumin, a group receiving vitamin D, a group receiving both supplements, and a sham-operated group. This well-structured approach allowed us to effectively evaluate the separate and combined impacts of these supplements.
Over a span of 12 weeks, we observed that both curcumin and vitamin D contributed to reduced pain levels on their own. When used together, their analgesic effects were even stronger, providing better pain relief for the rats. Beyond pain relief, supplemental curcumin and vitamin D also showed promising results when we examined inflammatory markers in their serum. We found a decrease in markers of inflammation while levels of the anti-inflammatory cytokine interleukin-10 (IL-10) increased.
Furthermore, we noted improvements in antioxidant levels as well as a significant reduction in the oxidative stress marker known as Cartilage Oligomeric Matrix Protein (COMP). Histological analysis revealed that these supplements helped preserve joint structure and maintain cartilage integrity, while also reducing inflammation in the synovium.
Our findings emphasize the potential of curcumin and vitamin D as effective natural agents in managing knee OA and associated pain. These results could suggest a way to delay the progression of knee OA and improve patient care.
Over a span of 12 weeks, we observed that both curcumin and vitamin D contributed to reduced pain levels on their own. When used together, their analgesic effects were even stronger, providing better pain relief for the rats. Beyond pain relief, supplemental curcumin and vitamin D also showed promising results when we examined inflammatory markers in their serum. We found a decrease in markers of inflammation while levels of the anti-inflammatory cytokine interleukin-10 (IL-10) increased.
Furthermore, we noted improvements in antioxidant levels as well as a significant reduction in the oxidative stress marker known as Cartilage Oligomeric Matrix Protein (COMP). Histological analysis revealed that these supplements helped preserve joint structure and maintain cartilage integrity, while also reducing inflammation in the synovium.
Our findings emphasize the potential of curcumin and vitamin D as effective natural agents in managing knee OA and associated pain. These results could suggest a way to delay the progression of knee OA and improve patient care.
9
In a well-structured study involving 101 adults suffering from knee osteoarthritis, we explored the effects of curcumin, a compound derived from turmeric, on knee pain. Participants were randomly assigned to receive either 500 mg of a standardized curcumin extract, Curcugen, twice daily, or a placebo for eight weeks, allowing for a clear comparison of its effectiveness.
Our findings revealed promising results. Curcumin significantly reduced knee pain scores and overall pain ratings compared to the placebo. We also noticed that participants taking curcumin showed greater improvements in various physical tests, like the timed up-and-go and six-minute walk tests, indicating enhanced mobility.
Interestingly, 37% of those on curcumin reduced their pain medications, which highlights the potential for curcumin to provide relief and improve quality of life for those with this condition. While the study didn’t explore longer treatment durations or different dosages, these initial results support curcumin's role as a feasible option for managing osteoarthritis pain in the knee.
Our findings revealed promising results. Curcumin significantly reduced knee pain scores and overall pain ratings compared to the placebo. We also noticed that participants taking curcumin showed greater improvements in various physical tests, like the timed up-and-go and six-minute walk tests, indicating enhanced mobility.
Interestingly, 37% of those on curcumin reduced their pain medications, which highlights the potential for curcumin to provide relief and improve quality of life for those with this condition. While the study didn’t explore longer treatment durations or different dosages, these initial results support curcumin's role as a feasible option for managing osteoarthritis pain in the knee.
9
Topical curcumin gel effectiveness
We conducted a study to explore the effectiveness of a unique topical gel infused with curcumin, a key ingredient in turmeric, for treating knee osteoarthritis. This innovative gel utilizes a self-nano-emulsifying organogel system, which allows for better delivery of curcumin, a compound known for its challenging solubility and stability issues.
In our research, we utilized a double-blind clinical trial design to assess the outcomes of participants using the gel compared to those receiving a placebo over an eight-week period. The results were promising; those applying the gel experienced significant reductions in pain, stiffness, and physical function difficulties. Specifically, pain scores improved by 71.68% compared to only 7.03% in the placebo group.
Overall, this study highlights the potential of using curcumin in a new topical treatment that addresses knee pain effectively. While the gel specifically utilizes curcumin, it offers an alternative approach that leverages the benefits of turmeric without relying directly on the spice itself.
In our research, we utilized a double-blind clinical trial design to assess the outcomes of participants using the gel compared to those receiving a placebo over an eight-week period. The results were promising; those applying the gel experienced significant reductions in pain, stiffness, and physical function difficulties. Specifically, pain scores improved by 71.68% compared to only 7.03% in the placebo group.
Overall, this study highlights the potential of using curcumin in a new topical treatment that addresses knee pain effectively. While the gel specifically utilizes curcumin, it offers an alternative approach that leverages the benefits of turmeric without relying directly on the spice itself.
8
Curcuminoids show promise for OA
We explored how curcuminoids, the active compounds in turmeric, can help alleviate knee pain associated with osteoarthritis (OA). This study critically examined various randomized controlled trials to focus solely on the use of curcuminoids without interference from other treatments.
Our findings suggest that curcuminoids can significantly reduce pain and improve function for those dealing with symptomatic knee OA in the short term. Importantly, we saw no increase in adverse events related to their use, indicating that curcuminoids are generally safe for patients.
However, we also noticed that the quality of the existing studies varies widely, and there is significant difference among them. This variability means we should approach the recommendation of curcuminoids for a broader clinical use cautiously. Additional high-quality research will be needed to refine dosages, administration methods, and long-term safety to better inform treatment decisions for patients suffering from knee pain.
Our findings suggest that curcuminoids can significantly reduce pain and improve function for those dealing with symptomatic knee OA in the short term. Importantly, we saw no increase in adverse events related to their use, indicating that curcuminoids are generally safe for patients.
However, we also noticed that the quality of the existing studies varies widely, and there is significant difference among them. This variability means we should approach the recommendation of curcuminoids for a broader clinical use cautiously. Additional high-quality research will be needed to refine dosages, administration methods, and long-term safety to better inform treatment decisions for patients suffering from knee pain.
References
- Mende LK, Kuthati Y, Wong CS. Curcumin and Vitamin D Supplement Attenuates Knee Osteoarthritis Progression in ACLT + MMx Rat Model: Effect on Cartilage Protection and Pain Reduction. Nutrients. 2025;17. doi:10.3390/nu17020349
- Hidayat R, Parlindungan F, Nisa JI, Mahendra AI, Indika MI, et al. Efficacy of in relieving pain symptoms of knee osteoarthritis patients: a systematic review and meta-analysis of clinical trials. J Rheum Dis. 2025;32:17. doi:10.4078/jrd.2024.0062
- Baharizade M, Ghetmiri SI, Mohammady M, Mohammadi-Samani S, Yousefi G. Revolutionizing Knee Osteoarthritis Treatment: Innovative Self-Nano-Emulsifying Polyethylene Glycol Organogel of Curcumin for Effective Topical Delivery. AAPS PharmSciTech. 2024;25:80. doi:10.1208/s12249-024-02789-8
- Bideshki MV, Jourabchi-Ghadim N, Radkhah N, Behzadi M, Asemani S, et al. The efficacy of curcumin in relieving osteoarthritis: A meta-analysis of meta-analyses. Phytother Res. 2024;38:2875. doi:10.1002/ptr.8153
- Zhao J, Liang G, Zhou G, Hong K, Yang W, et al. Efficacy and safety of curcumin therapy for knee osteoarthritis: A Bayesian network meta-analysis. J Ethnopharmacol. 2024;321:117493. doi:10.1016/j.jep.2023.117493
- Valsamidou E, Amerikanou C, Tzavara C, Skarpas G, Mariolis-Sapsakos TD, et al. A standardized nutraceutical supplement contributes to pain relief, improves quality of life and regulates inflammation in knee osteoarthritis patients; A randomized clinical trial. Heliyon. 2023;9:e20143. doi:10.1016/j.heliyon.2023.e20143
- Saber MM, Mahmoud MM, Amin HM, Essam RM. Therapeutic effects of combining curcumin and swimming in osteoarthritis using a rat model. Biomed Pharmacother. 2023;166:115309. doi:10.1016/j.biopha.2023.115309
- Kamat YD, Das B, Thakkar K, Mahajan M. A Retrospective Observational Study Evaluating the Synergistic Effect of a Novel Combination of Alfapin + Native Type 2 Collagen + Mobilee (Hyaluronic Acid) + CurQlife (Curcumin) Nutraceuticals in the Symptomatic Improvement of Knee Osteoarthritis. Cureus. 2023;15:e36123. doi:10.7759/cureus.36123
- Sengupta S, Tripathi A. Evaluation of analgesic and prophylactic activity of curcumin against chikungunya-infected acute/chronic arthralgic mice. J Med Virol. 2023;95:e28661. doi:10.1002/jmv.28661
- Raj JP, Venkatachalam S, S Amaravati R. Safety and Efficacy of Moderately-High Dose Turmacin® (Turmerosaccharide >10% w/w) Supplementation on Joint Discomfort in Healthy Adults - A Pilot Proof-of-Concept Single Arm Study. J Diet Suppl. 2024;21:28. doi:10.1080/19390211.2023.2176577
- Feng J, Li Z, Tian L, Mu P, Hu Y, et al. Efficacy and safety of curcuminoids alone in alleviating pain and dysfunction for knee osteoarthritis: a systematic review and meta-analysis of randomized controlled trials. BMC Complement Med Ther. 2022;22:276. doi:10.1186/s12906-022-03740-9
- Mathieu S, Soubrier M, Peirs C, Monfoulet LE, Boirie Y, et al. A Meta-Analysis of the Impact of Nutritional Supplementation on Osteoarthritis Symptoms. Nutrients. 2022;14. doi:10.3390/nu14081607
- Lopresti AL, Smith SJ, Jackson-Michel S, Fairchild T. An Investigation into the Effects of a Curcumin Extract (Curcugen) on Osteoarthritis Pain of the Knee: A Randomised, Double-Blind, Placebo-Controlled Study. Nutrients. 2021;14. doi:10.3390/nu14010041
- Hsiao AF, Lien YC, Tzeng IS, Liu CT, Chou SH, et al. The efficacy of high- and low-dose curcumin in knee osteoarthritis: A systematic review and meta-analysis. Complement Ther Med. 2021;63:102775. doi:10.1016/j.ctim.2021.102775
- Shokri-Mashhadi N, Bagherniya M, Askari G, Sathyapalan T, Sahebkar A. A Systematic Review of the Clinical Use of Curcumin for the Treatment of Osteoarthritis. Adv Exp Med Biol. 2021;1291:265. doi:10.1007/978-3-030-56153-6_16
- Dai W, Yan W, Leng X, Chen J, Hu X, et al. Effectiveness of Curcuma longa extract versus placebo for the treatment of knee osteoarthritis: A systematic review and meta-analysis of randomized controlled trials. Phytother Res. 2021;35:5921. doi:10.1002/ptr.7204
