We conducted a pilot trial to explore the effectiveness of zinc acetate in treating chronic refractory cough, a condition that causes significant discomfort for many people. In this study, we compared zinc acetate against a placebo over a period of six weeks, with the aim of measuring improvements in quality of life and cough symptoms using several established questionnaires.
Our group included 34 participants who were primarily white females suffering from moderate to severe cough. Throughout the trial, we noted that those taking zinc acetate did experience a rise in serum zinc levels, which indicates that the treatment was effective in that regard. However, when assessing the overall impact on cough symptoms and quality of life, both the zinc and placebo groups showed improvements, but those improvements were minimal.
Importantly, the treatment effects observed did not reach the clinically meaningful thresholds that would suggest zinc acetate significantly benefits cough management. Therefore, we concluded that there is no substantial advantage to using zinc therapy over placebo for people dealing with chronic cough, and suggest that larger trials are unnecessary at this time.
Read More
9
Zinc therapy shows promise for cough
A Potential Novel Treatment for Chronic Cough in Long COVID Patients: Clearance of Epipharyngeal Residual SARS-CoV-2 Spike RNA by Epipharyngeal Abrasive Therapy.
We explored the effectiveness of Epipharyngeal Abrasive Therapy (EAT) in addressing chronic cough, particularly in the context of Long COVID. This treatment, prevalent in Japan, uses zinc chloride to reduce inflammation in the epipharyngeal mucosa. We followed a 21-year-old man whose chronic cough persisted for four months after a mild COVID-19 infection. Upon diagnosis, we identified chronic epipharyngitis as the culprit behind his ongoing cough.
The EAT involved weekly treatments for three months. We observed that this therapy not only cleared residual SARS-CoV-2 spike RNA from the epipharyngeal mucosa but also led to a decrease in inflammation and proinflammatory cytokines. While the application of zinc chloride was a significant part of the treatment, it was combined with other elements of EAT, making it challenging to isolate zinc's specific impact on cough relief.
Overall, we found that EAT could be a promising avenue for individuals suffering from chronic cough related to Long COVID, highlighting an innovative way to utilize zinc in managing this persistent symptom.
Read More
8
Zinc in mixed COVID treatment
Efficacy and Safety of Aspirin, Promethazine, and Micronutrients for Rapid Clinical Recovery in Mild to Moderate COVID-19 Patients: A Randomized Controlled Clinical Trial.
We conducted a rigorous randomized controlled trial to evaluate the effectiveness of an innovative treatment involving a combination of two tablets: one with Aspirin and Promethazine, and another packed with essential micronutrients like vitamin D3, C, B3, zinc, and selenium. Our aim was to determine how this combination affects the symptoms of mild to moderate COVID-19, particularly cough.
Our study included 260 patients and followed a strict methodology, comparing this new treatment to the standard clinical management recommended by the Indian Council of Medical Research. Over a treatment period of 10 days, we observed notable improvements in symptoms, including cough, myalgia, headache, and anosmia, among those who received the APMV2020 treatment alongside standard care.
While zinc was included in the treatment, this study does not isolate its effect on cough specifically since it was part of a comprehensive combination. However, our findings indicated that APMV2020 treatment led to a significant reduction in cough symptoms and inflammatory markers. This positions APMV2020 as a promising candidate for inclusion in COVID-19 management protocols, not only for rapid recovery but also for its potential long-term benefits in reducing complications associated with the virus.
Read More
Most Useful Reviews
9
Indispensable assistant
7 people found this helpful
I find this vitamin excellent for my family. Taking zinc with vitamin C is indispensable at the first signs of weakness or cough. The next day, I felt revitalised, and I love this brand for its great price and quality.
Read More
9
Soothing for cough
1 people found this helpful
I bought these for my child but tried them myself. They worked well for my relentless cough when my throat was heavily tickling. They effectively soothed the cough, and I was very pleased, always carrying them with me now.
Read More
9
Relieves symptoms
1 people found this helpful
This product is amazing. It's especially effective when dealing with a cold and cough. I give it to my children, and it alleviates symptoms and helps remove phlegm. The pacifier form eliminates the need for infusion preparation, making it particularly effective for kids.
A Potential Novel Treatment for Chronic Cough in Long COVID Patients: Clearance of Epipharyngeal Residual SARS-CoV-2 Spike RNA by Epipharyngeal Abrasive Therapy.
We explored the effectiveness of Epipharyngeal Abrasive Therapy (EAT) in addressing chronic cough, particularly in the context of Long COVID. This treatment, prevalent in Japan, uses zinc chloride to reduce inflammation in the epipharyngeal mucosa. We followed a 21-year-old man whose chronic cough persisted for four months after a mild COVID-19 infection. Upon diagnosis, we identified chronic epipharyngitis as the culprit behind his ongoing cough.
The EAT involved weekly treatments for three months. We observed that this therapy not only cleared residual SARS-CoV-2 spike RNA from the epipharyngeal mucosa but also led to a decrease in inflammation and proinflammatory cytokines. While the application of zinc chloride was a significant part of the treatment, it was combined with other elements of EAT, making it challenging to isolate zinc's specific impact on cough relief.
Overall, we found that EAT could be a promising avenue for individuals suffering from chronic cough related to Long COVID, highlighting an innovative way to utilize zinc in managing this persistent symptom.
Read More
8
Zinc in mixed COVID treatment
Efficacy and Safety of Aspirin, Promethazine, and Micronutrients for Rapid Clinical Recovery in Mild to Moderate COVID-19 Patients: A Randomized Controlled Clinical Trial.
We conducted a rigorous randomized controlled trial to evaluate the effectiveness of an innovative treatment involving a combination of two tablets: one with Aspirin and Promethazine, and another packed with essential micronutrients like vitamin D3, C, B3, zinc, and selenium. Our aim was to determine how this combination affects the symptoms of mild to moderate COVID-19, particularly cough.
Our study included 260 patients and followed a strict methodology, comparing this new treatment to the standard clinical management recommended by the Indian Council of Medical Research. Over a treatment period of 10 days, we observed notable improvements in symptoms, including cough, myalgia, headache, and anosmia, among those who received the APMV2020 treatment alongside standard care.
While zinc was included in the treatment, this study does not isolate its effect on cough specifically since it was part of a comprehensive combination. However, our findings indicated that APMV2020 treatment led to a significant reduction in cough symptoms and inflammatory markers. This positions APMV2020 as a promising candidate for inclusion in COVID-19 management protocols, not only for rapid recovery but also for its potential long-term benefits in reducing complications associated with the virus.
Read More
7
Elderberry aids COPD symptoms
Clinical Effectiveness of a Combination of Black Elder Berries, Violet Herb, and Calendula Flowers in Chronic Obstructive Pulmonary Disease: The Results of a Double-Blinded Placebo-Controlled Study.
In our recent study, we investigated the potential benefits of a natural preparation called Inflaminat, which includes black elderberry, violet herb, and calendula flowers, on cough and other symptoms of chronic obstructive pulmonary disease (COPD). Conducted over six months, this randomized double-blind placebo-controlled trial involved 60 patients with moderate COPD.
We observed that those taking Inflaminat experienced a significant improvement in their symptoms as measured by the Breathlessness, Cough, and Sputum Scale. Specifically, their scores decreased from an average of 3.0 to 1.9, indicating less breathlessness and fewer cough symptoms. Additionally, their lung function improved, with a marked increase in the FEV1 measurement from 66% to 73%.
Importantly, participants in the placebo group showed no similar improvements, reinforcing the effectiveness of the natural remedy. Furthermore, we found no side effects associated with the preparation. Our findings suggest that herbal remedies, particularly those containing elderberry, could be valuable in alleviating cough and improving respiratory function in patients suffering from COPD.
Read More
2
Zinc acetate ineffective for cough
Efficacy and tolerability of zinc acetate for treatment of chronic refractory cough: pilot randomised futility trial.
We conducted a pilot trial to explore the effectiveness of zinc acetate in treating chronic refractory cough, a condition that causes significant discomfort for many people. In this study, we compared zinc acetate against a placebo over a period of six weeks, with the aim of measuring improvements in quality of life and cough symptoms using several established questionnaires.
Our group included 34 participants who were primarily white females suffering from moderate to severe cough. Throughout the trial, we noted that those taking zinc acetate did experience a rise in serum zinc levels, which indicates that the treatment was effective in that regard. However, when assessing the overall impact on cough symptoms and quality of life, both the zinc and placebo groups showed improvements, but those improvements were minimal.
Importantly, the treatment effects observed did not reach the clinically meaningful thresholds that would suggest zinc acetate significantly benefits cough management. Therefore, we concluded that there is no substantial advantage to using zinc therapy over placebo for people dealing with chronic cough, and suggest that larger trials are unnecessary at this time.
Read More
User Reviews
USERS' SCORE
Good
Based on 75 Reviews
8
All Reviews
Positive Reviews
Negative Reviews
9
Indispensable assistant
7 people found this helpful
I find this vitamin excellent for my family. Taking zinc with vitamin C is indispensable at the first signs of weakness or cough. The next day, I felt revitalised, and I love this brand for its great price and quality.
Read More
9
Soothing for cough
1 people found this helpful
I bought these for my child but tried them myself. They worked well for my relentless cough when my throat was heavily tickling. They effectively soothed the cough, and I was very pleased, always carrying them with me now.
Read More
9
Relieves symptoms
1 people found this helpful
This product is amazing. It's especially effective when dealing with a cold and cough. I give it to my children, and it alleviates symptoms and helps remove phlegm. The pacifier form eliminates the need for infusion preparation, making it particularly effective for kids.
Read More
9
Subdued tonsil pain
1 people found this helpful
I began coughing, and my daughter had throat pain; after taking this, it eased overnight. The zinc, Vitamin C, and elderberry seem effective against colds and viruses. It has a pleasant taste and is easy to consume.
Read More
10
No more colds
I take it at the first symptoms of a cold and since this product entered my home, there is no cold or cough in our family. Thank you!
Coughing is a reflex action that helps clear the airways of mucus, irritants, or foreign particles. It is a natural mechanism the body uses to protect itself and can be triggered by various factors, including infections, allergies, or environmental irritants. There are two main types of coughs: acute coughs, which typically last less than three weeks and often result from a cold or respiratory infection, and chronic coughs, which persist for more than eight weeks and may indicate a more serious underlying condition.
Coughs can also be classified as dry or productive. A dry cough does not produce mucus, while a productive cough does. Treatment options depend on the underlying cause; over-the-counter medications, home remedies, or medical intervention may be recommended based on the severity and duration of the cough. If a cough is persistent, accompanied by other symptoms like fever, shortness of breath, or chest pain, it’s advisable to seek medical advice for a proper diagnosis and treatment plan.
Elderberry (Sambucus) refers to a genus of flowering plants in the family Adoxaceae, comprising several species known for their small berries and traditional medicinal uses. The most commonly recognized species is the European elder, Sambucus nigra, which has been utilized in folk medicine for centuries due to its rich nutrient profile, including antioxidants, vitamins A and C, and dietary fiber. Elderberries are typically fragrant clusters of small, dark purple to black berries that are used in a variety of culinary applications, such as jams, syrups, and wine.
In recent years, elderberry has gained popularity for its potential health benefits, particularly for supporting immune health. Many people consume elderberry supplements or syrups to help alleviate symptoms of colds and flu, with some studies suggesting they may reduce the duration and severity of viral infections. However, it’s important to note that raw elderberries, as well as other parts of the elderberry plant, can be toxic if consumed in large amounts. Therefore, it's recommended to use elderberry products that are properly processed and prepared to ensure safety and efficacy.
While elderberry has gained popularity as a natural remedy for various ailments, including colds and respiratory issues, scientific evidence on its effectiveness specifically for cough relief is limited. Elderberry, particularly in syrup form, is often used to bolster the immune system and may help reduce symptoms of the flu and cold. Some users report that it can alleviate respiratory symptoms, including cough, possibly due to its anti-inflammatory properties. However, more research is needed to fully understand its impact on coughs.
If you're considering elderberry for cough relief, it's a good idea to consult with a healthcare professional, especially if you have pre-existing conditions or are taking other medications. While elderberry can be part of a holistic approach to managing cough and cold symptoms, it should not replace conventional treatments or medical advice. Always look for high-quality elderberry products to ensure potency and safety, and consider it alongside other remedies or treatments to maximize its potential benefits.
Based on user reviews, many individuals report experiencing positive results fairly quickly when taking the supplement for cough relief. For instance, one user noted that their child's cough significantly reduced within just four days of starting the treatment Read Review. Another reviewer shared that the cough disappeared overnight after administering the product, highlighting its rapid effectiveness Read Review. Similarly, several users emphasized that the lozenges work best when taken at the first signs of a cold or cough, suggesting that immediate consumption can lead to faster relief Read Review, Read Review.
While there is some research exploring the use of zinc in addressing cough symptoms, findings suggest that its effectiveness may be limited. A pilot study on zinc acetate indicated that while participants did experience a rise in serum zinc levels, improvements in cough symptoms and quality of life did not reach clinically meaningful thresholds when compared to placebo [1]. This suggests that zinc therapy does not provide substantial benefits for individuals suffering from chronic cough.
On the other hand, another study examining a novel treatment approach involving Epipharyngeal Abrasive Therapy (EAT) did show promise for addressing chronic cough post-COVID-19, utilizing zinc chloride as a component of a multifaceted therapeutic plan [2]. However, since zinc was part of a broader treatment, it is challenging to determine its specific efficacy. Therefore, while there is interest in the role of zinc in cough management, particularly in conjunction with other therapies, the current evidence does not robustly support its standalone use for alleviating cough symptoms.
Users have reported notable improvements in symptoms when using this vitamin supplement, particularly in relation to cough relief and cold management. Many reviewers highlighted that they experienced significant alleviation of symptoms within a short time frame. For instance, one user indicated that giving their child the lozenges during a cold led to a noticeable reduction in coughing and a runny nose in just two days Read Review. Another user noted that their sore throat and coughing were alleviated within three days of use, demonstrating the product's effectiveness in providing fast relief Read Review.
In addition to rapid symptom relief, multiple users found that integrating these lozenges into their regimen helped prevent illness altogether. One reviewer mentioned that since adding these vitamins to their family's health routine, they have noticed no occurrences of colds or coughs Read Review. Overall, while individual results may vary based on personal health conditions and circumstances, the general consensus among users points to a high level of satisfaction and effective symptom relief with the use of this product.
Users have reported positive experiences in combining this supplement with other vitamins, particularly zinc and vitamin C, to enhance its effectiveness for handling coughs. Many reviewers highlighted that integrating these additional supplements during the onset of symptoms significantly improved their overall health. One user noted that taking zinc with vitamin C was indispensable at the first signs of a cough, leading to revitalization by the next day Read Review. Another user observed that using these lozenges with vitamin C and zinc effectively addressed their child’s cold-related symptoms, including persistent coughing Read Review.
The consensus among users indicates that fortifying the supplementation routine with these vitamins not only helps to alleviate cough symptoms more swiftly but may also improve general immune response. A reviewer emphasized that elderberry combined with zinc and vitamin C works wonders during winter, underscoring a well-rounded preventive strategy against respiratory issues Read Review. Additionally, one parent reported that since integrating these lozenges into their child's regimen along with vitamin C and D, they experienced minimal cold symptoms, suggesting an effective approach to managing coughs and colds Read Review.
Based on existing research, elderberry, specifically in a formulation known as Inflaminat, has shown promising effects in alleviating cough symptoms and improving respiratory function in individuals with conditions such as chronic obstructive pulmonary disease (COPD). In a randomized double-blind placebo-controlled trial involving 60 patients, those taking the elderberry-containing preparation experienced a significant decrease in their cough and overall respiratory symptoms, with their scores on the Breathlessness, Cough, and Sputum Scale improving dramatically—from an average of 3.0 to 1.9. This study highlights the potential of elderberry as a beneficial natural remedy for cough, especially when dealing with chronic respiratory illnesses like COPD [4].
While the specific optimal dosage for elderberry sambucus wasn't detailed in the provided research, the outcomes indicate that formulations containing elderberry can effectively contribute to symptom relief for cough. Thus, when considering elderberry for cough management, it's advisable to consult health professionals for personalized guidance on dosage, ensuring that you benefit from its therapeutic effects safely and effectively.
9
Reduces cough quickly
My 4-year-old had a runny nose and cough, so I started giving zinc with vitamin C and elderberry, just one tablet daily. By day four, her runny nose reduced significantly, and the cough decreased as well. I highly recommend this combination!
9
Subdued tonsil pain
1 people found this helpful
I began coughing, and my daughter had throat pain; after taking this, it eased overnight. The zinc, Vitamin C, and elderberry seem effective against colds and viruses. It has a pleasant taste and is easy to consume.
10
Effective for cough
Wonderful! Essential during the cold season. When ordering these vitamins, I was uncertain about their effect! I ordered them for my child to help with frequent illnesses. Previously, we were sick every two weeks, suffering from runny nose and cough. After starting these vitamins, we began going to kindergarten every day without issue. If I notice the onset of illness, I give one tablet, which dissolves easily. These are essential in the autumn-spring season. Thank you, I will be ordering more.
9
Helps effectively
I give the lozenges to the child at the first sign of a cough. They work well and assist in quicker healing.
10
Quick recovery
The best elderberry for both children and adults! I bought it for my 5-year-old during a cold, and it works 100%. Three plates a day, and the runny nose, sneezing, and coughing improved in nearly 2 days. The taste is sweet and sour, and the child enjoys it.
9
Prevents coughing
An outstanding product! I give it to my child before school as a preventive measure. I also used it for my sore throat and within three days, the discomfort and the urge to cough disappeared. I will definitely continue to purchase these rather than resorting to expensive pills. Highly recommended!
10
No more colds
I take it at the first symptoms of a cold and since this product entered my home, there is no cold or cough in our family. Thank you!
9
Indispensable assistant
7 people found this helpful
I find this vitamin excellent for my family. Taking zinc with vitamin C is indispensable at the first signs of weakness or cough. The next day, I felt revitalised, and I love this brand for its great price and quality.
9
No cough symptoms
My child is allergic and only 3 years old. When ill with a virus, we often had a cough for 1.5 months, followed by a month of antihistamines. Our immunologist recommended zinc with elderberry and ascorbic acid, which I ordered immediately at a reasonable price. The child enjoyed the tasty lozenges, taking one daily during her cold. To my surprise, there was no cough, and she was active by the fourth day. This was the first time she was sick for only three days. I will order two more jars next time.
9
Best cough remedy
Elderberry is my go-to remedy for cough, especially in combination with zinc and vitamin C. It works wonders during winter!
9
Mild cold symptoms
They helped us! With the start of September, as the children returned to school, a runny nose and cough began. I started giving them these tasty lozenges, and the elder child noted that the throat discomfort disappeared. I also provided vitamin C and D. To my surprise, the cold was very mild!
2
Zinc acetate ineffective for cough
Efficacy and tolerability of zinc acetate for treatment of chronic refractory cough: pilot randomised futility trial.
We conducted a pilot trial to explore the effectiveness of zinc acetate in treating chronic refractory cough, a condition that causes significant discomfort for many people. In this study, we compared zinc acetate against a placebo over a period of six weeks, with the aim of measuring improvements in quality of life and cough symptoms using several established questionnaires.
Our group included 34 participants who were primarily white females suffering from moderate to severe cough. Throughout the trial, we noted that those taking zinc acetate did experience a rise in serum zinc levels, which indicates that the treatment was effective in that regard. However, when assessing the overall impact on cough symptoms and quality of life, both the zinc and placebo groups showed improvements, but those improvements were minimal.
Importantly, the treatment effects observed did not reach the clinically meaningful thresholds that would suggest zinc acetate significantly benefits cough management. Therefore, we concluded that there is no substantial advantage to using zinc therapy over placebo for people dealing with chronic cough, and suggest that larger trials are unnecessary at this time.
9
Zinc therapy shows promise for cough
A Potential Novel Treatment for Chronic Cough in Long COVID Patients: Clearance of Epipharyngeal Residual SARS-CoV-2 Spike RNA by Epipharyngeal Abrasive Therapy.
We explored the effectiveness of Epipharyngeal Abrasive Therapy (EAT) in addressing chronic cough, particularly in the context of Long COVID. This treatment, prevalent in Japan, uses zinc chloride to reduce inflammation in the epipharyngeal mucosa. We followed a 21-year-old man whose chronic cough persisted for four months after a mild COVID-19 infection. Upon diagnosis, we identified chronic epipharyngitis as the culprit behind his ongoing cough.
The EAT involved weekly treatments for three months. We observed that this therapy not only cleared residual SARS-CoV-2 spike RNA from the epipharyngeal mucosa but also led to a decrease in inflammation and proinflammatory cytokines. While the application of zinc chloride was a significant part of the treatment, it was combined with other elements of EAT, making it challenging to isolate zinc's specific impact on cough relief.
Overall, we found that EAT could be a promising avenue for individuals suffering from chronic cough related to Long COVID, highlighting an innovative way to utilize zinc in managing this persistent symptom.
7
Elderberry aids COPD symptoms
Clinical Effectiveness of a Combination of Black Elder Berries, Violet Herb, and Calendula Flowers in Chronic Obstructive Pulmonary Disease: The Results of a Double-Blinded Placebo-Controlled Study.
In our recent study, we investigated the potential benefits of a natural preparation called Inflaminat, which includes black elderberry, violet herb, and calendula flowers, on cough and other symptoms of chronic obstructive pulmonary disease (COPD). Conducted over six months, this randomized double-blind placebo-controlled trial involved 60 patients with moderate COPD.
We observed that those taking Inflaminat experienced a significant improvement in their symptoms as measured by the Breathlessness, Cough, and Sputum Scale. Specifically, their scores decreased from an average of 3.0 to 1.9, indicating less breathlessness and fewer cough symptoms. Additionally, their lung function improved, with a marked increase in the FEV1 measurement from 66% to 73%.
Importantly, participants in the placebo group showed no similar improvements, reinforcing the effectiveness of the natural remedy. Furthermore, we found no side effects associated with the preparation. Our findings suggest that herbal remedies, particularly those containing elderberry, could be valuable in alleviating cough and improving respiratory function in patients suffering from COPD.
References
Balasubramanian A, Holbrook JT, Canning BJ, Que LG, Castro M, et al. Efficacy and tolerability of zinc acetate for treatment of chronic refractory cough: pilot randomised futility trial. ERJ Open Res. 2023;9. doi:10.1183/23120541.00678-2022
Nishi K, Yoshimoto S, Tanaka T, Kimura S, Shinchi Y, et al. A Potential Novel Treatment for Chronic Cough in Long COVID Patients: Clearance of Epipharyngeal Residual SARS-CoV-2 Spike RNA by Epipharyngeal Abrasive Therapy. Cureus. 2023;15:e33421. doi:10.7759/cureus.33421
Kumar GS, Vadgaonkar A, Purunaik S, Shelatkar R, Vaidya VG, et al. Efficacy and Safety of Aspirin, Promethazine, and Micronutrients for Rapid Clinical Recovery in Mild to Moderate COVID-19 Patients: A Randomized Controlled Clinical Trial. Cureus. 2022;14:e25467. doi:10.7759/cureus.25467
Kirichenko TV, Sobenin IA, Markina YV, Gerasimova EV, Grechko AV, et al. Clinical Effectiveness of a Combination of Black Elder Berries, Violet Herb, and Calendula Flowers in Chronic Obstructive Pulmonary Disease: The Results of a Double-Blinded Placebo-Controlled Study. Biology (Basel). 2020;9. doi:10.3390/biology9040083