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NOW Supplements Sambucus Zinc-C Elderberry Concentrate and Vitamin C
SCIENTIFIC SCORE
Possibly Effective
Based on 5 Researches
7.8
USERS' SCORE
Good
Based on 3 Reviews
8.7
Supplement Facts
Serving Size:  1 Lozenge
Amount Per Serving
%DV
Calories
<5
 
Total Carbohydrate
<1 g
<1%**
Total Sugars
0 g
Includes 0 g Added Sugars
 
0%**
Xylitol
<1 g
Vitamin C (as Ascorbic Acid)
100 mg
111%
Zinc (elemental) (from 15 mg Zinc Bisglycinate) (TRAACS™)
3 mg
27%
Elderberry (10:1 Concentrate)(Sambucus nigra) (Fruit)
150 mg

Top Medical Research Studies

9
Zinc alleviates diabetic muscle atrophy
Zinc Alleviates Diabetic Muscle Atrophy via Modulation of the SIRT1/FoxO1 Autophagy Pathway Through GPR39.
High relevance to diabetes treatment
Our investigation aimed to understand how zinc affects muscle atrophy in diabetes, a serious complication that leads to muscle loss. Using diabetes-induced mice, we treated them with zinc sulfate for six weeks and observed notable improvements in their muscle condition.

We conducted various analyses to evaluate the impact of zinc on autophagy—the process that helps manage muscle mass. The results were promising; zinc appeared to enhance muscle recovery by regulating specific molecular pathways connected to muscle health.

Additionally, our in vitro studies with diabetic muscle cells revealed similar results, with zinc supplementation proving beneficial in reducing excessive autophagy. Overall, this suggests that incorporating zinc into treatment plans could be a promising approach to counteract muscle deterioration in diabetic patients.
Read More
8
Vitamin C improves diabetes control
Effects of water-soluble vitamins on glycemic control and insulin resistance in adult type 2 diabetes: an umbrella review of meta-analyses.
Relevant findings on vitamin C
We examined the effects of vitamin C supplementation on diabetes, focusing specifically on glycemic control and insulin resistance. Our analysis included a comprehensive review of fourteen systematic reviews and meta-analyses that assessed five different water-soluble vitamins: B-1, B-3, biotin, B-9 (folic acid), and C.

The findings revealed that vitamin C can significantly improve glycemic control in individuals with type 2 diabetes. We noticed reductions in fasting blood glucose levels and HbA1c, especially when supplementation lasted longer than 30 days. This is promising news for those managing diabetes, as it suggests that incorporating vitamin C could be beneficial.

Furthermore, we found that folic acid also plays a role in improving insulin resistance. However, there is a clear need for more well-designed randomized controlled trials to solidify these findings and develop a deeper understanding of the relationship between water-soluble vitamins and diabetes management.
Read More
8
Vitamin C may lower diabetes risk
Association between dietary antioxidant levels and diabetes: a cross-sectional study.
Direct association of vitamin C.
We explored the relationship between dietary antioxidants, particularly vitamin C, and diabetes risk using data from the National Health and Nutrition Examination Survey (NHANES) spanning from 2011 to 2018. This study sought to understand how different levels of dietary antioxidants might influence the prevalence of diabetes among adults in the U.S.

Our analysis involved 7,982 participants with a mean age of 47 years, comprising roughly equal numbers of men and women. Through comprehensive dietary recall interviews, we calculated the Composite Dietary Antioxidant Index (CDAI) based on the intake of key antioxidants, including vitamin C. The results revealed that higher intake of vitamin C was linked to a lower prevalence of diabetes, a finding that felt significant.

Specifically, we found that as vitamin C intake increased, the risk of diabetes decreased, particularly among women. Other antioxidants like zinc showed a trend towards reduced risk, but the data for vitamin C was clearer. Overall, our findings highlight vitamin C's potential role in reducing diabetes risk, supporting the idea that a balanced diet rich in antioxidants can be beneficial for our health.
Read More

Most Useful Reviews

9.5
Cold symptoms relief
I bought this for my son, who has a decade of experience managing diabetes. An endocrinologist recommended it. The results were swift; while on holiday, he took one lozenge daily, and by the second evening, his cold symptoms vanished. Typically, it takes longer to recover even with a high dose of vitamin C. I highly recommend this; it will now be a staple in our home first aid kit.
Read More
9.5
Sugar-free option
A good choice for individuals with diabetes as it does not contain sugar.
Read More
8.8
Enhances immunity
An excellent remedy for boosting immunity. I purchased it for my mother; she experienced average relief, taking two daily to recover, followed by one tablet for prevention. Elderberry is suitable for individuals with diabetes mellitus. The combination of zinc, vitamin C, and elderberry makes this product highly effective. Additionally, the price is very reasonable, and discounts are frequent. I will reorder for my mother and the whole family. The taste is pleasant with a hint of sourness.
Read More

Medical Researches

SCIENTIFIC SCORE
Possibly Effective
Based on 5 Researches
7.8
  • All Researches
9
Zinc alleviates diabetic muscle atrophy
Zinc Alleviates Diabetic Muscle Atrophy via Modulation of the SIRT1/FoxO1 Autophagy Pathway Through GPR39.
High relevance to diabetes treatment
Our investigation aimed to understand how zinc affects muscle atrophy in diabetes, a serious complication that leads to muscle loss. Using diabetes-induced mice, we treated them with zinc sulfate for six weeks and observed notable improvements in their muscle condition.

We conducted various analyses to evaluate the impact of zinc on autophagy—the process that helps manage muscle mass. The results were promising; zinc appeared to enhance muscle recovery by regulating specific molecular pathways connected to muscle health.

Additionally, our in vitro studies with diabetic muscle cells revealed similar results, with zinc supplementation proving beneficial in reducing excessive autophagy. Overall, this suggests that incorporating zinc into treatment plans could be a promising approach to counteract muscle deterioration in diabetic patients.
Read More
9
Bee venom and zinc against diabetes
Therapeutic Effects of Nanocoating of Apitoxin (Bee Venom) and Polyvinyl Alcohol Supplemented with Zinc Oxide Nanoparticles.
Partial relevance due to combination
We aimed to understand how zinc interacts with diabetes treatment through the lens of bee venom and zinc oxide nanoparticles. By creating a nanofilm using these components, we observed targeted therapeutic effects that may help manage diabetes effectively.

The combination of zinc oxide nanoparticles with bee venom significantly enhanced its ability to inhibit enzymes related to carbohydrate digestion, specifically α-amylase and α-glucosidase. Our findings indicated that the nanofilm achieved better results than bee venom alone, with lower inhibitory concentration values, showcasing its potential as an effective antidiabetic agent.

Furthermore, the nanofilm also demonstrated higher anti-inflammatory activity, offering an expansive view of the therapeutic benefits associated with this combination. While it’s important to note that zinc was just one element of the treatment, our research underscores its significance within this enhanced formulation aimed at combatting diabetes.
Read More
8
Vitamin C improves diabetes control
Effects of water-soluble vitamins on glycemic control and insulin resistance in adult type 2 diabetes: an umbrella review of meta-analyses.
Relevant findings on vitamin C
We examined the effects of vitamin C supplementation on diabetes, focusing specifically on glycemic control and insulin resistance. Our analysis included a comprehensive review of fourteen systematic reviews and meta-analyses that assessed five different water-soluble vitamins: B-1, B-3, biotin, B-9 (folic acid), and C.

The findings revealed that vitamin C can significantly improve glycemic control in individuals with type 2 diabetes. We noticed reductions in fasting blood glucose levels and HbA1c, especially when supplementation lasted longer than 30 days. This is promising news for those managing diabetes, as it suggests that incorporating vitamin C could be beneficial.

Furthermore, we found that folic acid also plays a role in improving insulin resistance. However, there is a clear need for more well-designed randomized controlled trials to solidify these findings and develop a deeper understanding of the relationship between water-soluble vitamins and diabetes management.
Read More
8
Vitamin C may lower diabetes risk
Association between dietary antioxidant levels and diabetes: a cross-sectional study.
Direct association of vitamin C.
We explored the relationship between dietary antioxidants, particularly vitamin C, and diabetes risk using data from the National Health and Nutrition Examination Survey (NHANES) spanning from 2011 to 2018. This study sought to understand how different levels of dietary antioxidants might influence the prevalence of diabetes among adults in the U.S.

Our analysis involved 7,982 participants with a mean age of 47 years, comprising roughly equal numbers of men and women. Through comprehensive dietary recall interviews, we calculated the Composite Dietary Antioxidant Index (CDAI) based on the intake of key antioxidants, including vitamin C. The results revealed that higher intake of vitamin C was linked to a lower prevalence of diabetes, a finding that felt significant.

Specifically, we found that as vitamin C intake increased, the risk of diabetes decreased, particularly among women. Other antioxidants like zinc showed a trend towards reduced risk, but the data for vitamin C was clearer. Overall, our findings highlight vitamin C's potential role in reducing diabetes risk, supporting the idea that a balanced diet rich in antioxidants can be beneficial for our health.
Read More
5
Cognitive benefits from Vitamin C
Evaluation of Cognitive and Synaptic Restoration in Diabetic Rats Treated With Emblica officinalis, Clitoria ternatea, Vitamin C, and Metformin.
Vitamin C's limited efficacy observed
We examined how Vitamin C influences cognitive function and synaptic density in diabetic rats. The study involved various experimental groups, including diabetic and non-diabetic controls, each receiving different treatments such as Emblica officinalis (EO), Clitoria ternatea (CT), Vitamin C, and Metformin. By using the Morris water maze test to assess spatial learning and memory over several time points, we aimed to uncover any potential benefits of Vitamin C in mitigating diabetes-related cognitive challenges.

Over the course of the study, we observed that the diabetic rats treated with Vitamin C did show some improvements in cognitive performance compared to the control group. However, these enhancements were not as pronounced as those seen in groups receiving EO or CT, and Vitamin C was outperformed by Metformin. By the end of the testing period, while there was an indication of improvement, the benefits of Vitamin C in isolation were less impressive and may not fully address the cognitive impairments associated with diabetes.

Thus, while Vitamin C appears to contribute positively when combined with other treatments, we need to recognize that its effectiveness on its own may be limited in the context of diabetes management. Overall, our findings suggest that while Vitamin C can play a role, other treatments may provide stronger support for cognitive function in diabetic models.
Read More

User Reviews

USERS' SCORE
Good
Based on 3 Reviews
8.7
  • All Reviews
  • Positive Reviews
  • Negative Reviews
9.5
Cold symptoms relief
I bought this for my son, who has a decade of experience managing diabetes. An endocrinologist recommended it. The results were swift; while on holiday, he took one lozenge daily, and by the second evening, his cold symptoms vanished. Typically, it takes longer to recover even with a high dose of vitamin C. I highly recommend this; it will now be a staple in our home first aid kit.
Read More
9.5
Sugar-free option
A good choice for individuals with diabetes as it does not contain sugar.
8.8
Enhances immunity
An excellent remedy for boosting immunity. I purchased it for my mother; she experienced average relief, taking two daily to recover, followed by one tablet for prevention. Elderberry is suitable for individuals with diabetes mellitus. The combination of zinc, vitamin C, and elderberry makes this product highly effective. Additionally, the price is very reasonable, and discounts are frequent. I will reorder for my mother and the whole family. The taste is pleasant with a hint of sourness.
Read More
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