We observed that omega-3 fatty acids, particularly EPA and DHA, could be beneficial for patients struggling with acne. Over 16 weeks, 60 participants followed a Mediterranean diet and received algae-derived omega-3 supplements.
We found that most patients initially had low omega-3 levels, but these rose significantly during the study. Acne severity showed notable improvement, especially in those achieving optimal omega-3 levels. Though four patients reported worsened appearance, overall quality of life improved for the majority.
Read More
9
Docosahexaenoic acid reduces acne risk
The causal association between polyunsaturated fatty acids and acne: A two-sample Mendelian randomization study.
We investigated the relationship between docosahexaenoic acid (DHA), a type of polyunsaturated fatty acid (PUFA), and the occurrence of acne. Using a method called Mendelian randomization, we looked at how genetic variations associated with DHA might influence acne development in large groups of participants, including over 115,000 individuals from the UK and nearly 364,000 of Finnish ancestry.
Our findings revealed that higher levels of DHA are actually linked to a lower risk of developing acne. Specifically, we found that a significant increase in DHA levels or its proportion compared to total fatty acids corresponded with a reduced likelihood of acne. In contrast, higher levels of linoleic acid (LA), another type of PUFA, were associated with an increased acne risk.
This suggests that balancing our intake of these fatty acids might be important for skin health. Notably, the results pointed towards a genetic connection involving the FADS1 gene, which appears to play a role in how these fatty acids affect our skin.
In conclusion, increasing DHA could be beneficial in protecting against acne, while excessive linoleic acid might have the opposite effect. Overall, our study highlights the importance of these fatty acids in understanding acne risk better.
Read More
8
Impact of fatty acids on acne
Exploring clinical and genetic evidence in association between unsaturated fatty acids and acne.
We systematically reviewed studies on how omega-3 and omega-6 fatty acids affect acne. Our findings indicate that omega-3s may help reduce acne, while some omega-6s could exacerbate it.
Additionally, our genetic analysis explored how these fatty acids interact with key enzymes related to acne. However, it's important to note that the study's population was limited primarily to Europeans, which may not reflect the broader community.
More diverse research is needed to fully understand these effects across different groups.
Read More
Most Useful Reviews
7.5
Reduced acne
150 people found this helpful
Omega 3 is brilliant, with a convenient dosage. Although the capsule is somewhat large, it is easy to swallow and is absorbed well, leaving no fishy aftertaste. The results are evident; my acne has decreased significantly, and the overall quality of my skin has improved.
Read More
9
Lasting results
100 people found this helpful
Initially sceptical, I found Omega-3 to be quite effective. My hair loss stopped within a month, and my son's persistent acne has cleared completely. We've decided to order more, given the significant results.
Read More
9
Less acne scars
80 people found this helpful
After a month and a half of taking this, I’ve noticed my rough skin has improved and my acne scars have faded. My nails are growing beautifully, and my skin appears glossier. I’ve maintained a healthy diet and exercise, contributing to my energy levels.
We observed that omega-3 fatty acids, particularly EPA and DHA, could be beneficial for patients struggling with acne. Over 16 weeks, 60 participants followed a Mediterranean diet and received algae-derived omega-3 supplements.
We found that most patients initially had low omega-3 levels, but these rose significantly during the study. Acne severity showed notable improvement, especially in those achieving optimal omega-3 levels. Though four patients reported worsened appearance, overall quality of life improved for the majority.
Read More
9
Docosahexaenoic acid reduces acne risk
The causal association between polyunsaturated fatty acids and acne: A two-sample Mendelian randomization study.
We investigated the relationship between docosahexaenoic acid (DHA), a type of polyunsaturated fatty acid (PUFA), and the occurrence of acne. Using a method called Mendelian randomization, we looked at how genetic variations associated with DHA might influence acne development in large groups of participants, including over 115,000 individuals from the UK and nearly 364,000 of Finnish ancestry.
Our findings revealed that higher levels of DHA are actually linked to a lower risk of developing acne. Specifically, we found that a significant increase in DHA levels or its proportion compared to total fatty acids corresponded with a reduced likelihood of acne. In contrast, higher levels of linoleic acid (LA), another type of PUFA, were associated with an increased acne risk.
This suggests that balancing our intake of these fatty acids might be important for skin health. Notably, the results pointed towards a genetic connection involving the FADS1 gene, which appears to play a role in how these fatty acids affect our skin.
In conclusion, increasing DHA could be beneficial in protecting against acne, while excessive linoleic acid might have the opposite effect. Overall, our study highlights the importance of these fatty acids in understanding acne risk better.
Read More
8
Impact of fatty acids on acne
Exploring clinical and genetic evidence in association between unsaturated fatty acids and acne.
We systematically reviewed studies on how omega-3 and omega-6 fatty acids affect acne. Our findings indicate that omega-3s may help reduce acne, while some omega-6s could exacerbate it.
Additionally, our genetic analysis explored how these fatty acids interact with key enzymes related to acne. However, it's important to note that the study's population was limited primarily to Europeans, which may not reflect the broader community.
More diverse research is needed to fully understand these effects across different groups.
Read More
8
Omega-3 effects on acne studied
The adjuvant treatment role of ω-3 fatty acids by regulating gut microbiota positively in the acne vulgaris.
We investigated whether omega-3 fatty acids could help manage acne by influencing gut bacteria. Over 12 weeks, untreated acne patients were divided into two groups: one received omega-3 supplements while the other didn’t. We also tested in rats with an acne model. The findings indicated that omega-3 increased gut bacteria diversity and enhanced beneficial bacteria linked to anti-inflammatory effects. However, despite these promising changes, we did not observe a significant overall impact on acne improvement in patients.
Read More
8
Omega-3 improves acne symptoms
Effect of dietary supplementation with omega-3 fatty acid and gamma-linolenic acid on acne vulgaris: a randomised, double-blind, controlled trial.
We examined how omega-3 fatty acids and gamma-linolenic acid could help with acne in a well-structured 10-week study. Involving 45 participants with mild to moderate acne, we compared those taking omega-3, those taking gamma-linolenic acid, and a control group.
The findings were promising: both omega-3 and gamma-linolenic acid showed a significant reduction in both inflammatory and non-inflammatory acne lesions. Participants also reported noticeable improvements in their skin. Importantly, no severe side effects were noted, indicating these supplements might be a beneficial addition to existing acne treatments.
Omega 3 is brilliant, with a convenient dosage. Although the capsule is somewhat large, it is easy to swallow and is absorbed well, leaving no fishy aftertaste. The results are evident; my acne has decreased significantly, and the overall quality of my skin has improved.
Read More
9
Lasting results
100 people found this helpful
Initially sceptical, I found Omega-3 to be quite effective. My hair loss stopped within a month, and my son's persistent acne has cleared completely. We've decided to order more, given the significant results.
Read More
9
Less acne scars
80 people found this helpful
After a month and a half of taking this, I’ve noticed my rough skin has improved and my acne scars have faded. My nails are growing beautifully, and my skin appears glossier. I’ve maintained a healthy diet and exercise, contributing to my energy levels.
Read More
9
Helps with acne
17 people found this helpful
This omega-3 supplement offers great value for money. It aids collagen preservation and improves skin conditions like acne, whilst promoting heart health and overall well-being. Regular intake is crucial for benefits, especially for mental health and maintaining a positive outlook.
Read More
0
Worsened acne
5 people found this helpful
I ordered this Omega based on good reviews, but it worsened my skin condition with subcutaneous acne. Discontinuing the product improved my skin, and I experienced severe stomach pain as well. I do not recommend it.
Acne is a common skin condition that affects people of all ages, though it's especially prevalent among teenagers and young adults. It occurs when hair follicles become clogged with oil and dead skin cells, leading to the formation of pimples, blackheads, and cysts. The main factors contributing to acne include excess oil production, hormonal changes, and the presence of bacteria on the skin. Acne can manifest in various forms, from mild cases with just a few breakouts to more severe forms that can cause significant inflammation and scarring.
Treatment for acne varies depending on its severity and can range from over-the-counter topical treatments like benzoyl peroxide and salicylic acid to prescription medications including retinoids and antibiotics. Lifestyle adjustments, such as maintaining a balanced diet and proper skin hygiene, may also contribute to managing and reducing breakouts. Despite being a common skin issue, the psychological impact of acne should not be underestimated, as it can affect self-esteem and overall quality of life.
Omega-3 fish oil is a nutritional supplement derived from the fatty tissues of fish, particularly fatty fish like salmon, mackerel, and sardines. It is rich in omega-3 fatty acids, which are essential fats that the body cannot produce on its own. The most significant types of omega-3s found in fish oil are eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), both of which are known for their numerous health benefits. These include reducing inflammation, supporting heart health, and promoting brain function.
Incorporating omega-3 fish oil into your diet can be beneficial if you don’t consume enough fish regularly. Many health experts recommend oily fish as a part of a balanced diet due to their high omega-3 content. For those who find it difficult to include fish in their meals, fish oil supplements can offer a convenient alternative, providing the same essential fatty acids in concentrated form. However, it’s essential to choose high-quality supplements that are third-party tested for purity and potency to avoid contaminants such as heavy metals or other toxins that can impact health.
Research on the effects of Omega-3 fish oil on acne suggests that it may offer some benefits, particularly due to its anti-inflammatory properties. Omega-3 fatty acids, which are found in fish oil, are known to help reduce inflammation in the body, and since acne is often associated with inflammatory processes, some individuals may experience a decrease in the severity or frequency of their breakouts. Additionally, Omega-3s can help improve skin hydration and may support overall skin health, which can be beneficial for those dealing with acne-prone skin.
However, while some studies have shown promising results, the evidence is not definitive enough to make Omega-3 fish oil a guaranteed solution for acne. It is also worth noting that dietary changes and supplements should complement a comprehensive skincare regimen tailored to individual skin types and needs. If you're considering adding Omega-3 supplements to your routine for acne management, it's a good idea to consult with a healthcare professional to ensure it aligns with your overall health goals and skincare plan.
Based on user reviews, the time it takes to see results from Omega-3 supplements for treating acne can vary widely. Some users report improvements in just a couple of weeks; for instance, one user noted a significant decrease in facial inflammation within two weeks of starting the supplement Read Review. Another user mentioned a remarkable improvement in their skin condition within three months, leading to softer skin and a reduction in chin acne Read Review.
However, it's important to note that not everyone experiences positive results; some users faced worsened skin conditions soon after starting the supplement. Instances of new acne development were reported shortly after beginning or increasing the dosage of Omega-3 Read Review. This indicates that while many may see results fairly quickly, others could encounter adverse effects that delay or prevent improvement. As with any supplement, results may differ based on individual skin reactions and health conditions.
Recent research suggests that omega-3 fatty acids, particularly eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), may have beneficial effects on acne treatment. Several studies have indicated that increasing omega-3 levels can lead to significant improvements in acne severity, particularly among individuals with initially low omega-3 levels. For instance, a controlled study demonstrated that participants who took algae-derived omega-3 supplements experienced reduced inflammatory and non-inflammatory lesions after 16 weeks ([2]). Moreover, another investigation found that participants receiving omega-3 supplementation reported marked improvements in their quality of life, indicating that this supplement may aid not only in managing acne but also in enhancing overall well-being ([2]).
However, it's essential to note that while omega-3 fatty acids appear to offer potential benefits, they are not a standalone cure for acne. A systematic review concluded that while omega-3s may help reduce acne-related inflammation, their efficacy varies, and they should be viewed as a complement to traditional acne treatments rather than a replacement ([5]). Furthermore, certain omega-6 fatty acids can exacerbate acne, underscoring the need for a balanced approach to fatty acid intake for optimal skin health. In summary, omega-3 fatty acids show promise for improving acne conditions, yet more diverse and extensive research is necessary to fully understand their effects across different populations.
Based on user reviews, many individuals have experienced beneficial improvements in their skin health after incorporating Omega-3 supplements into their routines. Users report significant decreases in acne, with one person noting that their son’s persistent acne cleared completely within a month of use Read Review. Others have observed improvements in skin texture, such as reduced roughness and faded acne scars, as well as an overall enhancement in skin appearance, including a glossier look Read Review. Some users have also mentioned positive effects on emotional well-being and energy levels, highlighting the multifaceted benefits of Omega-3 Read Review.
However, it's vital to note that individual results can vary significantly. While many rejoice in clear skin and reduced inflammation Read Review, others report adverse reactions, such as increased breakouts and skin irritation Read Review, indicating that some may have intolerances to the supplement. Discontinuing Omega-3 led to rapid improvements for users who experienced adverse effects, illustrating the importance of personalized evaluation when considering this supplement for acne treatment Read Review. Therefore, while many users have found Omega-3 beneficial for acne relief, others have encountered complications that prevent a straightforward endorsement.
Based on user reviews, opinions on combining Omega-3 supplements with other products for acne relief vary significantly. Some users have found greater success when pairing Omega-3 with Vitamin D, suggesting this combination maximizes effects on skin health Read Review. However, others experienced adverse reactions regardless of additional supplements, including severe breakouts, which suggests that individual tolerance to Omega-3 can greatly affect overall results Read Review.
For some users, increasing the dosage resulted in new acne outbreaks, leading them to discontinue use altogether Read Review. While many report that Omega-3 has positively influenced their skin by reducing acne and inflammation Read Review, the experiences of those who faced worsening conditions underscore the importance of personalized approaches in supplement regimens. Therefore, anyone considering combining Omega-3 with other supplements should proceed with caution and monitor their skin’s response closely.
When it comes to using Omega-3 Fish Oil for treating acne, research suggests that a daily dosage of around 2,000 to 3,000 milligrams may offer the most benefit. In a controlled study involving 45 participants with mild to moderate acne, those receiving 2,000 mg of eicosapentaenoic acid (EPA)—a key omega-3 fatty acid—showed significant reductions in both inflammatory and non-inflammatory acne lesions over a 10-week period [7]. Furthermore, individuals taking three grams of fish oil daily for 12 weeks experienced varied outcomes, with some reporting improvement in their skin condition, especially those with moderate to severe acne, suggests potential for effectiveness in this dosage range [8].
Additionally, research indicates that increasing omega-3 levels can have a positive impact on overall quality of life for acne patients, as well as reducing the side effects of other acne treatments [4]. However, it's important to note that results can vary significantly from person to person, and while omega-3s can play a supportive role in acne management, they should not be considered a standalone solution. If you're considering omega-3 supplementation for acne treatment, it's wise to consult with a healthcare provider to tailor the dosage to your individual needs [5].
9
Decreased inflammation
1 people found this helpful
This Omega-3 has worked wonders for my hormonal acne. Within two weeks, I noticed a significant decrease in facial inflammation that I’d dealt with for years. I am extremely pleased and hope this improvement continues.
9
Softer skin
1 people found this helpful
After three months of taking this, my skin has become softer, and my chin acne disappeared. When I stopped taking it, my skin stiffened, confirming its beneficial impact on reducing acne. I intend to continue taking it.
0
Acne outbreak
2 people found this helpful
After initially taking one capsule, I saw no changes. However, both my husband and I broke out in spots all over our faces after escalating the dose. We stopped, and soon after, the acne cleared up. I plan to finish the bottle but won’t take it again.
9
Lasting results
100 people found this helpful
Initially sceptical, I found Omega-3 to be quite effective. My hair loss stopped within a month, and my son's persistent acne has cleared completely. We've decided to order more, given the significant results.
9
Less acne scars
80 people found this helpful
After a month and a half of taking this, I’ve noticed my rough skin has improved and my acne scars have faded. My nails are growing beautifully, and my skin appears glossier. I’ve maintained a healthy diet and exercise, contributing to my energy levels.
9
Cognitive support
1 people found this helpful
I take Omega-3 regularly as it reduces the risk of heart problems and supports my memory. It has helped with my overall emotional state and eased chronic fatigue and acne. I recommend it highly.
0
Worsened acne
5 people found this helpful
I ordered this Omega based on good reviews, but it worsened my skin condition with subcutaneous acne. Discontinuing the product improved my skin, and I experienced severe stomach pain as well. I do not recommend it.
0
Acne onset
1 people found this helpful
Since I began taking it daily, small pimples appeared on my chin and forehead. After stopping, my skin improved within days. Be cautious with this product.
9
Skin benefits
12 people found this helpful
I highly recommend omega-3 for its numerous skin benefits, especially for acne sufferers. Combining it with vitamin D maximises the effects. It’s essential to take it consistently for the best results.
0
Caused acne
I had high hopes for this omega-3, but unfortunately, it causes my acne to flare up noticeably even with just one pill a day. After stopping, my skin clears up, but the acne returns when I resume taking it. I warn you about this possible reaction.
9
Omega-3 improves acne severity
Exploring the potential of omega-3 fatty acids in acne patients: A prospective intervention study.
We observed that omega-3 fatty acids, particularly EPA and DHA, could be beneficial for patients struggling with acne. Over 16 weeks, 60 participants followed a Mediterranean diet and received algae-derived omega-3 supplements.
We found that most patients initially had low omega-3 levels, but these rose significantly during the study. Acne severity showed notable improvement, especially in those achieving optimal omega-3 levels. Though four patients reported worsened appearance, overall quality of life improved for the majority.
7
Omega-3s benefit inflammatory skin conditions
The Potential Uses of Omega-3 Fatty Acids in Dermatology: A Review.
We examined a variety of studies on omega-3 fatty acids (O3FAs) and their impact on skin conditions, including acne. The review encompassed 38 studies, highlighting benefits such as a reduction in inflammatory lesions and side effects from other acne treatments like isotretinoin.
Although the findings suggest potential advantages, specifically for inflammatory skin issues, O3FAs are best viewed as a supplemental option rather than a standalone solution for acne. Overall, their low cost and safety make them a viable addition to treatment strategies for those seeking to improve their skin health.
8
Omega-3 improves acne symptoms
Effect of dietary supplementation with omega-3 fatty acid and gamma-linolenic acid on acne vulgaris: a randomised, double-blind, controlled trial.
We examined how omega-3 fatty acids and gamma-linolenic acid could help with acne in a well-structured 10-week study. Involving 45 participants with mild to moderate acne, we compared those taking omega-3, those taking gamma-linolenic acid, and a control group.
The findings were promising: both omega-3 and gamma-linolenic acid showed a significant reduction in both inflammatory and non-inflammatory acne lesions. Participants also reported noticeable improvements in their skin. Importantly, no severe side effects were noted, indicating these supplements might be a beneficial addition to existing acne treatments.
4
Fish oil may improve acne severity
Effects of fish oil supplementation on inflammatory acne.
We evaluated the effects of omega-3 fish oil on inflammatory acne in a group of 13 individuals over 12 weeks. Each participant continued their regular acne treatments while taking three grams of fish oil daily.
While the overall results showed no significant changes in acne severity scores or inflammatory lesion counts, we observed varied individual responses. Eight participants showed improvement, particularly those with moderate to severe acne, while four experienced worsening conditions.
These findings suggest that omega-3 supplementation may be beneficial for some, but further research is necessary to confirm its effectiveness.
7
Omega-3 reduces isotretinoin side effects
Effectiveness Of Oral Omega 3 In Reducing Mucocutaneous Side Effects Of Oral Isotretinoin In Patients With Acne Vulgaris.
We set out to investigate whether omega-3 fish oil could reduce the common side effects associated with isotretinoin treatment in patients with acne vulgaris. In our randomized control trial involving 60 participants, we found that those taking omega-3 experienced significantly fewer issues like dry lips compared to those on a placebo.
Our findings suggest that omega-3 may offer a helpful solution for managing these mucocutaneous side effects, improving comfort during acne treatment. Overall, this research indicates that adding omega-3 could be beneficial for those taking isotretinoin.
References
Zhang L, Li Y, Pu Y, Dang T, Shi Q, et al. Exploring clinical and genetic evidence in association between unsaturated fatty acids and acne. Eur J Nutr. 2025;64:130. 10.1007/s00394-025-03647-4
Guertler A, Neu K, Lill D, Clanner-Engelshofen B, French LE, et al. Exploring the potential of omega-3 fatty acids in acne patients: A prospective intervention study. J Cosmet Dermatol. 2024;23:3295. 10.1111/jocd.16434
Huang Y, Liu F, Lai J, Jiang S, Tan X, et al. The adjuvant treatment role of ω-3 fatty acids by regulating gut microbiota positively in the acne vulgaris. J Dermatolog Treat. 2024;35:2299107. 10.1080/09546634.2023.2299107
Zainab Z, Malik NA, Obaid S, Malik S, Aftab K, et al. Effectiveness Of Oral Omega 3 In Reducing Mucocutaneous Side Effects Of Oral Isotretinoin In Patients With Acne Vulgaris. J Ayub Med Coll Abbottabad. 2021;33:60.
Thomsen BJ, Chow EY, Sapijaszko MJ. The Potential Uses of Omega-3 Fatty Acids in Dermatology: A Review. J Cutan Med Surg. 2020;24:481. 10.1177/1203475420929925
Aslan İ, Özcan F, Karaarslan T, Kıraç E, Aslan M. Decreased eicosapentaenoic acid levels in acne vulgaris reveals the presence of a proinflammatory state. Prostaglandins Other Lipid Mediat. 2017;128-129:1. 10.1016/j.prostaglandins.2016.12.001
Jung JY, Kwon HH, Hong JS, Yoon JY, Park MS, et al. Effect of dietary supplementation with omega-3 fatty acid and gamma-linolenic acid on acne vulgaris: a randomised, double-blind, controlled trial. Acta Derm Venereol. 2014;94:521. 10.2340/00015555-1802
Khayef G, Young J, Burns-Whitmore B, Spalding T. Effects of fish oil supplementation on inflammatory acne. Lipids Health Dis. 2012;11:165. 10.1186/1476-511X-11-165
Desbois AP, Lawlor KC. Antibacterial activity of long-chain polyunsaturated fatty acids against Propionibacterium acnes and Staphylococcus aureus. Mar Drugs. 2013;11:4544. 10.3390/md11114544
Rubin MG, Kim K, Logan AC. Acne vulgaris, mental health and omega-3 fatty acids: a report of cases. Lipids Health Dis. 2008;7:36. 10.1186/1476-511X-7-36
Kim BR, Kim G, Jin SP, Choi CW, Kim J, et al. The causal association between polyunsaturated fatty acids and acne: A two-sample Mendelian randomization study. Br J Dermatol. 2025. 10.1093/bjd/ljaf052