'
SCIENTIFIC SCORE
Possibly Effective
Based on 8 Researches
7.8
USERS' SCORE
Moderately Good
Based on 42 Reviews
7.7
Supplement Facts
Serving Size:   2 Softgels
Amount Per Serving
%DV
Calories
20
 
Total Fat
2 g
3%**
Saturated Fat
0.5 g
3%**
Polyunsaturated Fat
1 g
Monounsaturated Fat
0.5 g
Fish Oil Concentrate
2 g (2,000 mg)
Eicosapentaenoic Acid (EPA)
360 mg
Docosahexaenoic Acid (DHA)
240 mg

Top Medical Research Studies

9
Eicosapentaenoic acid helps acne
Exploring the potential of omega-3 fatty acids in acne patients: A prospective intervention study.
Directly addresses EPA's effects
We focused our research on the potential benefits of eicosapentaenoic acid (EPA), a type of omega-3 fatty acid, for individuals suffering from acne. Over a period of 16 weeks, we encouraged 60 patients to follow a Mediterranean diet while taking algae-derived EPA and docosahexaenoic acid (DHA) supplements. Our goal was to see if increasing their omega-3 levels could improve acne symptoms.

At the start of the study, an impressive 98.3% of the participants were found to have low levels of EPA/DHA. By the end of the study, we observed a significant increase in their omega-3 levels from an average of 4.9% to 8.3%. This boost correlated with noticeable improvements in both inflammatory and non-inflammatory acne lesions.

Interestingly, we noted that while individual perceptions of appearance varied—some reporting no improvement—overall quality of life for the participants enhanced significantly, particularly in those with papulopustular acne. Alongside dietary changes, participants reduced their intake of cow’s milk and dairy products, and we did not encounter any negative side effects from the intervention.

Ultimately, our findings suggest that boosting omega-3 fatty acids, particularly EPA, through diet and supplementation can effectively help manage acne severity in patients.
Read More
9
Docosahexaenoic acid reduces acne risk
The causal association between polyunsaturated fatty acids and acne: A two-sample Mendelian randomization study.
Highly relevant to DHA effects
We investigated the relationship between docosahexaenoic acid (DHA), a type of polyunsaturated fatty acid (PUFA), and the occurrence of acne. Using a method called Mendelian randomization, we looked at how genetic variations associated with DHA might influence acne development in large groups of participants, including over 115,000 individuals from the UK and nearly 364,000 of Finnish ancestry.

Our findings revealed that higher levels of DHA are actually linked to a lower risk of developing acne. Specifically, we found that a significant increase in DHA levels or its proportion compared to total fatty acids corresponded with a reduced likelihood of acne. In contrast, higher levels of linoleic acid (LA), another type of PUFA, were associated with an increased acne risk.

This suggests that balancing our intake of these fatty acids might be important for skin health. Notably, the results pointed towards a genetic connection involving the FADS1 gene, which appears to play a role in how these fatty acids affect our skin.

In conclusion, increasing DHA could be beneficial in protecting against acne, while excessive linoleic acid might have the opposite effect. Overall, our study highlights the importance of these fatty acids in understanding acne risk better.
Read More
9
DHA improves acne severity
Exploring the potential of omega-3 fatty acids in acne patients: A prospective intervention study.
Strong link between study and findings
We explored the potential benefits of docosahexaenoic acid (DHA), a type of omega-3 fatty acid, in treating acne. Over 16 weeks, 60 participants followed a Mediterranean diet paired with algae-derived DHA and eicosapentaenoic acid (EPA) supplementation. We aimed to boost their omega-3 levels and observe any changes in their acne severity.

Remarkably, our study found that nearly all participants started with a deficiency in omega-3 fatty acids. After the dietary and supplementation intervention, the average omega-3 index rose significantly, indicating improved levels of DHA and EPA. More importantly, participants experienced notable reductions in both inflammatory and non-inflammatory acne lesions.

While a few individuals reported that their skin appearance worsened, the collective quality of life among participants improved, especially for those with papulopustular acne. They also became more aware of dietary triggers and made healthier choices, like reducing cow's milk and dairy intake. Overall, we saw a promising link between increased omega-3 levels and improved acne outcomes.
Read More

Most Useful Reviews

8.8
Reduced acne
Omega 3 is brilliant, with a convenient dosage. Although the capsule is somewhat large, it is easy to swallow and is absorbed well, leaving no fishy aftertaste. The results are evident; my acne has decreased significantly, and the overall quality of my skin has improved.
Read More
8.3
Lasting results
Initially sceptical, I found Omega-3 to be quite effective. My hair loss stopped within a month, and my son's persistent acne has cleared completely. We've decided to order more, given the significant results.
Read More
9.5
Less acne scars
After a month and a half of taking this, I’ve noticed my rough skin has improved and my acne scars have faded. My nails are growing beautifully, and my skin appears glossier. I’ve maintained a healthy diet and exercise, contributing to my energy levels.
Read More

Medical Researches

SCIENTIFIC SCORE
Possibly Effective
Based on 8 Researches
7.8
9
Eicosapentaenoic acid helps acne
Exploring the potential of omega-3 fatty acids in acne patients: A prospective intervention study.
Directly addresses EPA's effects
We focused our research on the potential benefits of eicosapentaenoic acid (EPA), a type of omega-3 fatty acid, for individuals suffering from acne. Over a period of 16 weeks, we encouraged 60 patients to follow a Mediterranean diet while taking algae-derived EPA and docosahexaenoic acid (DHA) supplements. Our goal was to see if increasing their omega-3 levels could improve acne symptoms.

At the start of the study, an impressive 98.3% of the participants were found to have low levels of EPA/DHA. By the end of the study, we observed a significant increase in their omega-3 levels from an average of 4.9% to 8.3%. This boost correlated with noticeable improvements in both inflammatory and non-inflammatory acne lesions.

Interestingly, we noted that while individual perceptions of appearance varied—some reporting no improvement—overall quality of life for the participants enhanced significantly, particularly in those with papulopustular acne. Alongside dietary changes, participants reduced their intake of cow’s milk and dairy products, and we did not encounter any negative side effects from the intervention.

Ultimately, our findings suggest that boosting omega-3 fatty acids, particularly EPA, through diet and supplementation can effectively help manage acne severity in patients.
Read More
9
Docosahexaenoic acid reduces acne risk
The causal association between polyunsaturated fatty acids and acne: A two-sample Mendelian randomization study.
Highly relevant to DHA effects
We investigated the relationship between docosahexaenoic acid (DHA), a type of polyunsaturated fatty acid (PUFA), and the occurrence of acne. Using a method called Mendelian randomization, we looked at how genetic variations associated with DHA might influence acne development in large groups of participants, including over 115,000 individuals from the UK and nearly 364,000 of Finnish ancestry.

Our findings revealed that higher levels of DHA are actually linked to a lower risk of developing acne. Specifically, we found that a significant increase in DHA levels or its proportion compared to total fatty acids corresponded with a reduced likelihood of acne. In contrast, higher levels of linoleic acid (LA), another type of PUFA, were associated with an increased acne risk.

This suggests that balancing our intake of these fatty acids might be important for skin health. Notably, the results pointed towards a genetic connection involving the FADS1 gene, which appears to play a role in how these fatty acids affect our skin.

In conclusion, increasing DHA could be beneficial in protecting against acne, while excessive linoleic acid might have the opposite effect. Overall, our study highlights the importance of these fatty acids in understanding acne risk better.
Read More
9
DHA improves acne severity
Exploring the potential of omega-3 fatty acids in acne patients: A prospective intervention study.
Strong link between study and findings
We explored the potential benefits of docosahexaenoic acid (DHA), a type of omega-3 fatty acid, in treating acne. Over 16 weeks, 60 participants followed a Mediterranean diet paired with algae-derived DHA and eicosapentaenoic acid (EPA) supplementation. We aimed to boost their omega-3 levels and observe any changes in their acne severity.

Remarkably, our study found that nearly all participants started with a deficiency in omega-3 fatty acids. After the dietary and supplementation intervention, the average omega-3 index rose significantly, indicating improved levels of DHA and EPA. More importantly, participants experienced notable reductions in both inflammatory and non-inflammatory acne lesions.

While a few individuals reported that their skin appearance worsened, the collective quality of life among participants improved, especially for those with papulopustular acne. They also became more aware of dietary triggers and made healthier choices, like reducing cow's milk and dairy intake. Overall, we saw a promising link between increased omega-3 levels and improved acne outcomes.
Read More
8
Omega-3s beneficial for acne
Effect of dietary supplementation with omega-3 fatty acid and gamma-linolenic acid on acne vulgaris: a randomised, double-blind, controlled trial.
Strong relevance to eicosapentaenoic acid
We explored the potential of eicosapentaenoic acid, a key omega-3 fatty acid, in treating acne vulgaris through a structured study involving 45 participants with mild to moderate acne. Over ten weeks, participants were divided into three groups: one received 2,000 mg of eicosapentaenoic acid with docosahexaenoic acid, another got 400 mg of gamma-linolenic acid from borage oil, and a control group received no supplements.

After this supplementation period, we observed notable reductions in both inflammatory and non-inflammatory acne lesions in participants taking either the omega-3 or gamma-linolenic acid. The participants also reported improvements based on their personal assessments. Furthermore, histological examinations showed decreased inflammation and lower levels of interleukin-8, a marker related to acne inflammation.

Importantly, no severe adverse effects were reported, indicating that these fatty acids could be safely used alongside traditional acne treatments. Overall, this research suggests that eicosapentaenoic acid and gamma-linolenic acid may serve as valuable additions to acne management strategies.
Read More
8
Eicosapentaenoic acid shows promise
Antibacterial activity of long-chain polyunsaturated fatty acids against Propionibacterium acnes and Staphylococcus aureus.
Study indicates mixed effectiveness.
We aimed to explore the effectiveness of eicosapentaenoic acid (EPA) along with other long-chain polyunsaturated fatty acids (LC-PUFAs) in treating acne and superficial infections caused by the bacteria Propionibacterium acnes and Staphylococcus aureus. In our investigation, we found that these fatty acids exhibited antibacterial properties, with a range of effectiveness against the two types of bacteria.

The study revealed that P. acnes showed more sensitivity to the growth-inhibiting effects of LC-PUFAs compared to S. aureus. Interestingly, while these compounds were capable of stopping P. acnes growth, they were only bactericidal, meaning they could kill S. aureus. Our findings also included the discovery of the antibacterial activity in previously unreported fatty acids such as 15-hydroxyeicosapentaenoic acid (15-OHEPA) and 15-hydroxyeicosatrienoic acid (HETrE).

Additionally, we noted that when S. aureus was exposed to these fatty acids, the bacteria were effectively killed within a short timeframe, specifically between 15 to 30 minutes. Combining these LC-PUFAs with established treatments did not reduce their effectiveness and revealed potential potentiation of action, particularly in combinations with commonly used acne medications like benzoyl peroxide and neomycin.

In conclusion, our observations suggest that eicosapentaenoic acid and other LC-PUFAs may be valuable new options for treating skin infections caused by P. acnes and S. aureus, especially when used alongside conventional therapies. However, further studies are needed to fully understand their potential in clinical settings.
Read More

User Reviews

USERS' SCORE
Moderately Good
Based on 42 Reviews
7.7
9.5
Less acne scars
After a month and a half of taking this, I’ve noticed my rough skin has improved and my acne scars have faded. My nails are growing beautifully, and my skin appears glossier. I’ve maintained a healthy diet and exercise, contributing to my energy levels.
9.5
Helps with acne
This omega-3 supplement offers great value for money. It aids collagen preservation and improves skin conditions like acne, whilst promoting heart health and overall well-being. Regular intake is crucial for benefits, especially for mental health and maintaining a positive outlook.
9.5
Skin benefits
I highly recommend omega-3 for its numerous skin benefits, especially for acne sufferers. Combining it with vitamin D maximises the effects. It’s essential to take it consistently for the best results.
9.5
Acne improvement
After three months of using omega-3, I observed baby hairs and healthier nails. My skin signifies a remarkable improvement, with a noticeable reduction in acne, contributing to my overall energy and positivity.
9.5
Softer skin
After three months of taking this, my skin has become softer, and my chin acne disappeared. When I stopped taking it, my skin stiffened, confirming its beneficial impact on reducing acne. I intend to continue taking it.
image