Genetically Determined Plasma Docosahexaenoic Acid Showed a Causal Association with Female Reproductive Longevity-Related Phenotype: A Mendelian Randomization Study.
We investigated the link between omega-3 fatty acids and the timing of menopause. Using a Mendelian randomization approach, we analyzed data from thousands of women to assess how different fatty acids influenced reproductive longevity—specifically, the age at menopause.
Our findings revealed that higher plasma levels of DHA, a type of omega-3, were associated with a delayed onset of menopause. This suggests that increasing DHA could be a potential strategy for extending women's reproductive lifespan.
Read More
9
Omega-3 fish oil aids menopause health
Baroreflex sensitivity and central hemodynamics after omega-3 polyunsaturated fatty acids supplementation in an animal model of menopause.
We examined how omega-3 polyunsaturated fatty acids (n-3 PUFA) could protect against vascular issues linked to menopause using an ovariectomized rat model.
In our study, we found that n-3 PUFA supplementation helped maintain baroreflex sensitivity, which typically declines after ovariectomy.
Additionally, the central arterial pressure profile remained stable in treated rats, showing a potential protective effect against postmenopausal vascular issues. This suggests that omega-3 fish oil may offer therapeutic benefits during menopause.
Read More
8
Fish oil shows cognitive benefits
DHA-Enriched Fish Oil Ameliorates Deficits in Cognition Associated with Menopause and the Genotype in Rodents.
We investigated how DHA-enriched fish oil affects cognitive challenges associated with menopause, particularly in female mice carrying the APOE4 gene, known to increase Alzheimer's risk. Our findings suggest that while this fish oil improved recognition memory, it did not significantly enhance spatial working memory.
Furthermore, the fish oil raised levels of DHA and other beneficial compounds in the brain, hinting at its potential protective effects against menopause-related cognitive decline, especially for those at higher risk. Overall, our study indicates a promising role for DHA-rich fish oil in supporting brain health during menopause.
Read More
Most Useful Reviews
9
High quality supplement
I've ordered this supplement twice, as it's essential for my wife and me. It's high quality and helps reduce bad cholesterol while supporting menopause, joint health, and cardiovascular functions. I noticed my shoulder pain disappeared after using it. Highly recommend!
Read More
9
Improved mood stability
Omega stabilises conditions like insomnia and depression, especially during menopause and old age. It contains natural ingredients that enhance brain function and mood while allowing for better sleep.
Read More
9
Enhances health during menopause
These capsules are excellent and have made a noticeable difference in how I feel during menopause. My nails, skin, and hair have improved. I recommend purchasing them!
We examined the impact of omega 3 fish oil, paired with resistance exercise, on health in postmenopausal women. In our trial, 20 healthy older women took part in either a resistance training program with fish oil or a placebo for eight weeks.
Both groups showed improvements in physical function, but those taking fish oil experienced a notable boost in handgrip strength and lower blood pressure and inflammatory markers.
This suggests that fish oil could enhance muscle function and reduce health risks for women navigating menopause.
Read More
9
Omega-3s reduce menopause-related depression
Antidepressant activity of ω-3 polyunsaturated fatty acids in ovariectomized rats: role of neuroinflammation and microglial polarization.
We explored how omega-3 polyunsaturated fatty acids (PUFA) affect mood changes associated with menopause in ovariectomized rats. Our study revealed that menopause led to anxiety and depression-like behaviors, driven by increased neuroinflammation in the brain.
However, we found that omega-3 supplementation helped shift the brain's inflammatory response towards a healthier balance. The omega-3s not only assisted in reducing the negative mood symptoms but also promoted protective effects against neuroinflammation.
Overall, while omega-3 fatty acids show promise, more research is needed to fully understand their benefits for menopause-related issues.
Read More
9
Omega-3 fish oil aids menopause health
Baroreflex sensitivity and central hemodynamics after omega-3 polyunsaturated fatty acids supplementation in an animal model of menopause.
We examined how omega-3 polyunsaturated fatty acids (n-3 PUFA) could protect against vascular issues linked to menopause using an ovariectomized rat model.
In our study, we found that n-3 PUFA supplementation helped maintain baroreflex sensitivity, which typically declines after ovariectomy.
Additionally, the central arterial pressure profile remained stable in treated rats, showing a potential protective effect against postmenopausal vascular issues. This suggests that omega-3 fish oil may offer therapeutic benefits during menopause.
Read More
9
Eicosapentaenoic acid and estradiol
Association between polyunsaturated fatty acid intake and estradiol levels among U.S. women.
We explored the relationship between eicosapentaenoic acid (EPA) intake and estradiol levels in women, specifically focusing on its effects during menopause. The study utilized data from the National Health and Nutrition Examination Survey, which included dietary interviews and serum estradiol level measurements.
Our findings highlighted that higher intakes of EPA were associated with increased estradiol levels in both menopausal and non-menopausal women. Importantly, we noted that EPA intake above a certain threshold was linked to these hormonal changes.
This research suggests that incorporating more EPA into the diet could play a role in regulating estradiol levels, which is particularly beneficial for women's reproductive health during and after menopause. Understanding these connections helps emphasize the importance of nutrition in hormone regulation.
Read More
9
DHA linked to breast density changes
Omega-3 Fatty Acids Responsive Proteins and Reduction in Breast Density in Obese Postmenopausal Women.
We explored the relationship between docosahexaenoic acid (DHA), a type of omega-3 fatty acid, and breast density among postmenopausal women, particularly focusing on those who are obese. Our study aimed to understand how DHA might differentially affect breast density in obese versus nonobese women, using a method called iTRAQ to analyze plasma samples over two years.
During the study, we identified 173 proteins in the plasma samples. Some of these proteins showed different levels of expression based on whether women were obese or lean. Notably, proteins like the vitamin D binding protein and fibronectin were altered, which suggests a connection between DHA intake and reduced inflammation in obese women.
Our findings indicated that there is an inverse relationship between DHA levels and breast density specifically in postmenopausal obese women. This suggests that greater DHA intake could potentially reduce breast density and may decrease breast cancer risk in this demographic. However, it’s important to note that the effect was not observed in nonobese women.
Overall, this research highlights DHA's role in impacting breast health during menopause, particularly for those with obesity. It opens up further discussions on how dietary changes could play a role in cancer prevention strategies for women going through menopause.
I've ordered this supplement twice, as it's essential for my wife and me. It's high quality and helps reduce bad cholesterol while supporting menopause, joint health, and cardiovascular functions. I noticed my shoulder pain disappeared after using it. Highly recommend!
Read More
9
Improved mood stability
Omega stabilises conditions like insomnia and depression, especially during menopause and old age. It contains natural ingredients that enhance brain function and mood while allowing for better sleep.
Read More
9
Enhances health during menopause
These capsules are excellent and have made a noticeable difference in how I feel during menopause. My nails, skin, and hair have improved. I recommend purchasing them!
Read More
9
Necessary nutrition for menopause
DHA and EPA are vital for brain health and the body's function, especially during menopause. I ensure I get enough omega-3 fatty acids daily for my overall well-being, as they help regulate metabolism and improve health conditions associated with menopause.
Read More
7.5
Enhances emotional wellbeing
Omega-3 fatty acids improve brain function and relieve menopause symptoms, helping to stabilise my emotional state and reduce anxiety.
Menopause is a natural biological process that marks the end of a woman's reproductive years, characterized by the cessation of menstruation and a decline in hormonal levels, particularly estrogen and progesterone. Typically occurring between the ages of 45 and 55, menopause can bring a variety of physical and emotional changes. Common symptoms may include hot flashes, night sweats, mood swings, and changes in sleep patterns. It is important to note that menopause is a gradual process and often begins with perimenopause, where women may experience irregular periods and increased symptoms for several years before periods stop completely.
While menopause is a natural phase of life, it can have significant impacts on a woman's health and well-being. This transition can increase the risk of certain health issues, such as osteoporosis and cardiovascular disease, due in part to lowered hormone levels. Therefore, it is advisable for women to consult with healthcare providers to discuss potential management strategies and lifestyle adjustments during this time. These may include hormone replacement therapy, dietary changes, regular physical activity, and alternative therapies, all aimed at alleviating symptoms and promoting overall health during and after menopause.
Omega-3 fish oil is a nutritional supplement derived from the fatty tissues of fish, particularly fatty fish like salmon, mackerel, and sardines. It is rich in omega-3 fatty acids, which are essential fats that the body cannot produce on its own. The most significant types of omega-3s found in fish oil are eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), both of which are known for their numerous health benefits. These include reducing inflammation, supporting heart health, and promoting brain function.
Incorporating omega-3 fish oil into your diet can be beneficial if you don’t consume enough fish regularly. Many health experts recommend oily fish as a part of a balanced diet due to their high omega-3 content. For those who find it difficult to include fish in their meals, fish oil supplements can offer a convenient alternative, providing the same essential fatty acids in concentrated form. However, it’s essential to choose high-quality supplements that are third-party tested for purity and potency to avoid contaminants such as heavy metals or other toxins that can impact health.
Omega-3 fish oil has garnered attention for its potential health benefits, especially during menopause. Some studies suggest that omega-3 fatty acids may help alleviate certain menopause symptoms such as mood swings, anxiety, and hot flashes. The primary components of omega-3, EPA (eicosapentaenoic acid) and DHA (docosahexaenoic acid), have anti-inflammatory properties that can support overall hormonal balance and may offer cardiovascular benefits—an important consideration during menopause as heart health can become a greater concern for women.
While many women report feeling some relief from menopausal symptoms when incorporating omega-3 fish oil into their diets, it is essential to note that responses can vary significantly from person to person. Additionally, while omega-3s might be a helpful supplement, they should not be viewed as a standalone treatment. It’s best to consult with a healthcare provider to create a comprehensive approach to managing menopause symptoms, which can include lifestyle changes, dietary adjustments, and other therapies tailored to individual needs.
Based on user reviews, the time it typically takes to start seeing results from this menopause supplement can vary. Some users report noticeable improvements in their overall well-being and specific menopause symptoms shortly after they begin taking the supplement. For instance, one reviewer noted a significant difference in how they felt during menopause within a reasonable period of use, recommending the product based on their positive experience Read Review. Another user mentioned that the supplement helped stabilize conditions related to menopause, suggesting benefits might be felt within weeks Read Review.
While some users have reported quick results, it's important to note that individual responses can vary depending on factors like lifestyle, dosage, and overall health. A user who shifted to the supplement specifically for cholesterol management saw results over the course of a year, indicating that for some, it may take longer to experience the full benefits Read Review. Overall, while many users find benefits relatively quickly, patience may be required to fully gauge the supplement's impact.
Research indicates that omega-3 fatty acids, particularly docosahexaenoic acid (DHA), may be beneficial for women experiencing menopause. Studies have found a link between higher DHA levels and delayed onset of menopause, suggesting that increasing DHA intake could be a strategy for extending reproductive lifespan [2]. Additionally, DHA supplementation has shown promise in alleviating certain menopausal symptoms, such as improvements in psychological well-being and sexual function [11]. However, while some studies highlight benefits in lipid profiles and cardiovascular health [12], others suggest that omega-3 supplementation may not significantly reduce common menopausal discomforts like hot flashes or improve overall quality of life compared to other interventions [16].
Overall, while omega-3 supplements show potential benefits in managing some aspects of menopausal health, research findings also indicate variability in effectiveness. Some studies suggest that while omega-3s can enhance physical function and may support emotional health during menopause, their impact on menopausal symptoms remains inconclusive [5]. As many researchers call for further high-quality trials, it's clear that while omega-3s may play a role, they are not a one-size-fits-all solution for every woman experiencing menopause.
Based on user reviews, many individuals report a range of improvements in symptoms related to menopause and general health after using the supplement. Users have highlighted notable benefits such as reduced shoulder pain, increased emotional stability, and improvements in skin, nails, and hair health. For example, one reviewer emphasized how the supplement made a significant difference in their overall well-being during menopause, showcasing enhancements not just in menopause symptoms but also in general health aspects like skin and hair Read Review. Another user noted the supplement's effectiveness in alleviating anxiety and stabilizing their emotional state Read Review.
Furthermore, some users experienced benefits beyond menopause, including reduced levels of LDL cholesterol, which they attributed to the supplement after switching from traditional medications Read Review. There are also mentions of insomnia and mood improvements, showcasing the product's broad spectrum of supports that users appreciate Read Review. While these experiences are encouraging, it’s essential to remember that results can vary from person to person.
Based on user reviews, many individuals have found success in combining this supplement with others for managing menopause symptoms. Users often highlight the synergistic benefits of taking omega-3 fatty acids, like DHA and EPA, alongside the primary supplement. These essential fatty acids are praised for their contributions to brain health and mood stabilization, which can be particularly beneficial during menopause. One reviewer noted how including omega-3s helped regulate metabolism and improve health conditions tied to menopause, corroborating the notion that these nutrients work well together for optimal support Read Review.
Additionally, users have reported that the supplement aids in alleviating not only menopause symptoms but also related issues like anxiety and depression when used alongside omega-3 sources. A reviewer shared that this combination stabilized her emotional state, allowing for better overall well-being during menopause Read Review. Overall, the consensus among users suggests that pairing this supplement with other high-quality products, particularly those rich in omega-3s, can enhance the management of menopause symptoms and promote a more balanced emotional state.
Based on user reviews, there's consensus on the benefits of Omega 3 fish oil for managing menopause symptoms, though specific dosage recommendations are not typically mentioned. Users report that incorporating Omega 3 into their daily routine has significantly improved their overall well-being during menopause. For instance, one user highlights that DHA and EPA are essential for brain health and help regulate metabolism related to menopause symptoms, advocating for a consistent intake of omega-3 fatty acids for optimal health Read Review.
Others note the formulation of the supplement itself, with emphasis on quality and efficacy in alleviating menopause-related symptoms such as insomnia and emotional fluctuations Read Review. While users do not specify exact dosages, the general observation is that regular supplementation contributes positively to managing menopause symptoms. Given the varying personal experiences, potential users may want to consult healthcare professionals to determine the appropriate dosage tailored to their needs.
9
Enhances health during menopause
These capsules are excellent and have made a noticeable difference in how I feel during menopause. My nails, skin, and hair have improved. I recommend purchasing them!
9
Improved mood stability
Omega stabilises conditions like insomnia and depression, especially during menopause and old age. It contains natural ingredients that enhance brain function and mood while allowing for better sleep.
7.5
Normal cholesterol achieved
7 people found this helpful
My LDL cholesterol levels have decreased. After hearing that my cholesterol was high post-menopause, I shifted to this supplement for a year and now my levels are within the normal range. I prefer not to take hospital medication and wish to continue this.
7.5
Enhances emotional wellbeing
Omega-3 fatty acids improve brain function and relieve menopause symptoms, helping to stabilise my emotional state and reduce anxiety.
9
Necessary nutrition for menopause
DHA and EPA are vital for brain health and the body's function, especially during menopause. I ensure I get enough omega-3 fatty acids daily for my overall well-being, as they help regulate metabolism and improve health conditions associated with menopause.
8
Omega-3 links to menopause timing
Genetically Determined Plasma Docosahexaenoic Acid Showed a Causal Association with Female Reproductive Longevity-Related Phenotype: A Mendelian Randomization Study.
We investigated the link between omega-3 fatty acids and the timing of menopause. Using a Mendelian randomization approach, we analyzed data from thousands of women to assess how different fatty acids influenced reproductive longevity—specifically, the age at menopause.
Our findings revealed that higher plasma levels of DHA, a type of omega-3, were associated with a delayed onset of menopause. This suggests that increasing DHA could be a potential strategy for extending women's reproductive lifespan.
8
DHA shows potential for menopause relief
Neurovegetative disorders of perimenopausal women treated with docosahexaenoic acid (DHA, 625 mg).
We examined how DHA, at a dose of 625 mg, influences menopausal symptoms, sexual function, and overall quality of life in perimenopausal women. Involving 42 participants, we measured multiple aspects of their well-being using reputable indices over six months. Results indicated significant improvements in menopause symptoms and psychological quality of life. Particularly, sexual function scores improved, suggesting benefits for arousal and lubrication. However, physical quality of life showed no meaningful change. Thus, DHA appears promising in alleviating specific menopausal challenges and enhancing the sexual experience.
7
Omega-3 milk supports cardiovascular health
Daily Intake of Milk Enriched with n-3 Fatty Acids, Oleic Acid, and Calcium Improves Metabolic and Bone Biomarkers in Postmenopausal Women.
We examined the impact of a specialized low-lactose milk drink enriched with omega-3 fatty acids, oleic acid, and vitamins on postmenopausal women at moderate cardiovascular risk.
Over 12 months, the women consuming the enriched milk experienced significant improvements in their cholesterol levels and inflammation indicators, while those in the control group showed no changes.
However, we found no substantial effects on bone metabolism markers. This suggests that such dietary inclusions could support cardiovascular health in postmenopausal women.
4
Omega-3 shows no significant benefit
Menopausal quality of life: RCT of yoga, exercise, and omega-3 supplements.
We explored the impact of omega-3 fish oil on menopausal quality of life through a well-designed 12-week study. Involving 355 peri- and postmenopausal women, participants were divided into groups for yoga, exercise, usual activity, and omega-3 or placebo supplements.
While yoga demonstrated some positive effects, omega-3 did not show significant benefits in improving quality of life or menopausal symptoms. The results indicate that while yoga can aid menopausal women, omega-3 supplementation may not be a reliable option for enhancing their experience.
7
Omega-3's mixed menopause effects
n-3 PUFA Improve Emotion and Cognition during Menopause: A Systematic Review.
We explored how omega-3 polyunsaturated fatty acids (n-3 PUFA) could influence emotional health and cognitive function during menopause. An extensive review of 17 studies, including both human and animal research, revealed that n-3 PUFA is linked to reduced depressive symptoms.
However, results regarding anxiety and cognition in humans were mixed, while animal studies showed consistent benefits in both areas. Although n-3 PUFA appears promising for emotional and cognitive support during menopause, further research is needed to fully understand its potential.
References
Fan R, Kim J, Kim YC, Chung S. Effects of Fish Oil with Heat Treatment on Obesity, Inflammation, and Gut Microbiota in Ovariectomized Mice. Nutrients. 2025;17. doi:10.3390/nu17030549
Gao H, Ying Y, Sun J, Huang Y, Li X, et al. Genetically Determined Plasma Docosahexaenoic Acid Showed a Causal Association with Female Reproductive Longevity-Related Phenotype: A Mendelian Randomization Study. Nutrients. 2024;16. doi:10.3390/nu16234103
Lee SR, Directo D. Fish Oil Supplementation with Resistance Exercise Training Enhances Physical Function and Cardiometabolic Health in Postmenopausal Women. Nutrients. 2023;15. doi:10.3390/nu15214516
Feehan O, Magee PJ, Pourshahidi LK, Armstrong DJ, Slevin MM, et al. Associations of long chain polyunsaturated fatty acids with bone mineral density and bone turnover in postmenopausal women. Eur J Nutr. 2023;62:95. doi:10.1007/s00394-022-02933-9
Decandia D, Landolfo E, Sacchetti S, Gelfo F, Petrosini L, et al. n-3 PUFA Improve Emotion and Cognition during Menopause: A Systematic Review. Nutrients. 2022;14. doi:10.3390/nu14091982
Pontifex MG, Martinsen A, Saleh RNM, Harden G, Fox C, et al. DHA-Enriched Fish Oil Ameliorates Deficits in Cognition Associated with Menopause and the Genotype in Rodents. Nutrients. 2022;14. doi:10.3390/nu14091698
Félix-Soriano E, Martínez-Gayo A, Cobo MJ, Pérez-Chávez A, Ibáñez-Santos J, et al. Effects of DHA-Rich n-3 Fatty Acid Supplementation and/or Resistance Training on Body Composition and Cardiometabolic Biomarkers in Overweight and Obese Post-Menopausal Women. Nutrients. 2021;13. doi:10.3390/nu13072465
Purzand B, Rokhgireh S, Shabani Zanjani M, Eshraghi N, Mohamadianamiri M, et al. The comparison of the effect of soybean and fish oil on supplementation on menopausal symptoms in postmenopausal women: A randomized, double-blind, placebo-controlled trial. Complement Ther Clin Pract. 2020;41:101239. doi:10.1016/j.ctcp.2020.101239
Wu B, Song Q, Zhang Y, Wang C, Yang M, et al. Antidepressant activity of ω-3 polyunsaturated fatty acids in ovariectomized rats: role of neuroinflammation and microglial polarization. Lipids Health Dis. 2020;19:4. doi:10.1186/s12944-020-1185-2
Mohammady M, Janani L, Jahanfar S, Mousavi MS. Effect of omega-3 supplements on vasomotor symptoms in menopausal women: A systematic review and meta-analysis. Eur J Obstet Gynecol Reprod Biol. 2018;228:295. doi:10.1016/j.ejogrb.2018.07.008
Cianci A, Maiolino L, Giunta G, Rapisarda AMC, Di Mauro P, et al. Neurovegetative disorders of perimenopausal women treated with docosahexaenoic acid (DHA, 625 mg). Gynecol Endocrinol. 2017;33:980. doi:10.1080/09513590.2017.1334200
Fonolla-Joya J, Reyes-García R, García-Martín A, López-Huertas E, Muñoz-Torres M. Daily Intake of Milk Enriched with n-3 Fatty Acids, Oleic Acid, and Calcium Improves Metabolic and Bone Biomarkers in Postmenopausal Women. J Am Coll Nutr. 2016;35:529.
Alves Luzia L, Mendes Aldrighi J, Teixeira Damasceno NR, Rodrigues Sampaio G, Aparecida Manólio Soares R, et al. FISH OIL AND VITAMIN E CHANGE LIPID PROFILES AND ANTI-LDL-ANTIBODIES IN TWO DIFFERENT ETHNIC GROUPS OF WOMEN TRANSITIONING THROUGH MENOPAUSE. Nutr Hosp. 2015;32:165. doi:10.3305/nh.2015.32.1.9079
Losurdo P, Grillo A, Panizon E, Zanetti M, Bardelli M, et al. Baroreflex sensitivity and central hemodynamics after omega-3 polyunsaturated fatty acids supplementation in an animal model of menopause. Vascul Pharmacol. 2015;71:65. doi:10.1016/j.vph.2014.12.005
Tardivo AP, Nahas-Neto J, Orsatti CL, Dias FB, Poloni PF, et al. Effects of omega-3 on metabolic markers in postmenopausal women with metabolic syndrome. Climacteric. 2015;18:290. doi:10.3109/13697137.2014.981521
Reed SD, Guthrie KA, Newton KM, Anderson GL, Booth-LaForce C, et al. Menopausal quality of life: RCT of yoga, exercise, and omega-3 supplements. Am J Obstet Gynecol. 2014;210:244.e1. doi:10.1016/j.ajog.2013.11.016
Guo L, Nan Y, Liang K, Yao L, Li J. Association between polyunsaturated fatty acid intake and estradiol levels among U.S. women. Front Nutr. 2024;11:1500705. doi:10.3389/fnut.2024.1500705
So J, Yao JH, Magadmi R, Matthan NR, Lamon-Fava S. Sex differences in lipid mediators derived from omega-3 fatty acids in older individuals with low-grade chronic inflammation. Prostaglandins Leukot Essent Fatty Acids. 2024;203:102655. doi:10.1016/j.plefa.2024.102655
Putti JS, Engers VK, Heemann FM, Salomon TB, Benfato MS, et al. Effects of lipoic acid and ω-3 long-chain polyunsaturated fatty acids on the kidney in the ovariectomized rat model of menopause. Nutrition. 2019;66:173. doi:10.1016/j.nut.2019.05.003
Marinho PM, Salomon TB, Andrade AS, Behling CS, Putti JS, et al. The effect of n-3 long-chain polyunsaturated fatty acids and lipoic acid on the heart in the ovariectomized rat model of menopause. Free Radic Res. 2019;53:669. doi:10.1080/10715762.2019.1620938
Abshirini M, Siassi F, Koohdani F, Qorbani M, Khosravi S, et al. Higher intake of dietary n-3 PUFA and lower MUFA are associated with fewer menopausal symptoms. Climacteric. 2019;22:195. doi:10.1080/13697137.2018.1547700
Schüller ÁK, Mena Canata DA, Hackenhaar FS, Engers VK, Heemann FM, et al. Effects of lipoic acid and n-3 long-chain polyunsaturated fatty acid on the liver ovariectomized rat model of menopause. Pharmacol Rep. 2018;70:263. doi:10.1016/j.pharep.2017.10.006
Dong H, Hutchins-Wiese H, Kleppinger A, Annis K, Liva E, et al. Effects of Omega-3 Polyunsaturated Fatty Acid Supplementation on Bone Turnover in Older Women. Int J Vitam Nutr Res. 2014;84:124. doi:10.1024/0300-9831/a000199
Cohen LS, Joffe H, Guthrie KA, Ensrud KE, Freeman M, et al. Efficacy of omega-3 for vasomotor symptoms treatment: a randomized controlled trial. Menopause. 2014;21:347. doi:10.1097/GME.0b013e31829e40b8
Hutchins-Wiese HL, Kleppinger A, Annis K, Liva E, Lammi-Keefe CJ, et al. The impact of supplemental n-3 long chain polyunsaturated fatty acids and dietary antioxidants on physical performance in postmenopausal women. J Nutr Health Aging. 2013;17:76. doi:10.1007/s12603-012-0415-3
Scuderi G, Contestabile MT, Gagliano C, Iacovello D, Scuderi L, et al. Effects of phytoestrogen supplementation in postmenopausal women with dry eye syndrome: a randomized clinical trial. Can J Ophthalmol. 2012;47:489. doi:10.1016/j.jcjo.2012.08.019
Wattanathorn J, Thukham-Mee W. Omega-3-Rich Tuna Oil Derived from By-Products of the Canned Tuna Industry Enhances Memory in an Ovariectomized Rat Model of Menopause. Antioxidants (Basel). 2024;13. doi:10.3390/antiox13060637
Konuri A, Bhat KMR, Rai KS, Gourishetti K, Phaneendra M YS. Supplementation of fenugreek with choline-docosahexaenoic acid attenuates menopause induced memory loss, BDNF and dendritic arborization in ovariectomized rats. Anat Sci Int. 2021;96:197. doi:10.1007/s12565-020-00574-8
Sun YW, Xu H, Benitez G, Chen KM, Stanley A, et al. Omega-3 Fatty Acids Responsive Proteins and Reduction in Breast Density in Obese Postmenopausal Women. J Proteome Res. 2019;18:3461. doi:10.1021/acs.jproteome.9b00356
Sparkes C, Gibson R, Sinclair A, Else PL, Meyer BJ. Effect of Low Dose Docosahexaenoic Acid-Rich Fish Oil on Plasma Lipids and Lipoproteins in Pre-Menopausal Women: A Dose⁻Response Randomized Placebo-Controlled Trial. Nutrients. 2018;10. doi:10.3390/nu10101460
Jin Y, Kim TH, Park Y. Association between erythrocyte levels of n-3 polyunsaturated fatty acids and depression in postmenopausal women using or not using hormone therapy. Menopause. 2016;23:1012. doi:10.1097/GME.0000000000000667