' 
SCIENTIFIC SCORE
Questionable
Based on 32 Researches
6.8
USERS' SCORE
Good
Based on 2 Reviews
8.5
Supplement Facts
Serving Size: 1 Veg Capsule
Amount Per Serving
%DV
Vitamin C (as Ascorbic Acid)
250 mg
278%
Vitamin E (as d-alpha Tocopheryl Succinate)
20 mg
133%
Alpha Lipoic Acid
100 mg
†
Top Medical Research Studies
9
Vitamin C shows effectiveness for acne
Sodium L-ascorbyl-2-phosphate 5% lotion for the treatment of acne vulgaris: a randomized, double-blind, controlled trial.
Direct assessment of vitamin C
In our recent study, we set out to explore the effectiveness of a 5% sodium L-ascorbyl-2-phosphate lotion, a stable form of vitamin C, for treating acne. We conducted a double-blind, controlled trial with 50 participants over 12 weeks, where half used the vitamin C lotion and the other half received a placebo.
Our findings revealed significant improvements in acne symptoms for those using the vitamin C lotion compared to the placebo group. We measured outcomes through various assessments, including a global evaluation by investigators and self-reported assessments by the subjects, along with lesion counts.
The results showed that the vitamin C lotion was not only effective but also well-tolerated, with side effects similar to those seen with the placebo. This adds a promising tool to the options available for acne treatment, suggesting that vitamin C might play a valuable role in skincare regimens aimed at combating acne.
Overall, our study supports the idea that vitamin C, in the form of sodium L-ascorbyl-2-phosphate, can help reduce acne, making it a noteworthy addition to acne treatment strategies.
Our findings revealed significant improvements in acne symptoms for those using the vitamin C lotion compared to the placebo group. We measured outcomes through various assessments, including a global evaluation by investigators and self-reported assessments by the subjects, along with lesion counts.
The results showed that the vitamin C lotion was not only effective but also well-tolerated, with side effects similar to those seen with the placebo. This adds a promising tool to the options available for acne treatment, suggesting that vitamin C might play a valuable role in skincare regimens aimed at combating acne.
Overall, our study supports the idea that vitamin C, in the form of sodium L-ascorbyl-2-phosphate, can help reduce acne, making it a noteworthy addition to acne treatment strategies.
Read More
9
Sodium ascorbyl phosphate for acne
Sodium ascorbyl phosphate shows in vitro and in vivo efficacy in the prevention and treatment of acne vulgaris.
Strong antimicrobial, effective treatment
We explored the potential of sodium ascorbyl phosphate (SAP), a stable form of vitamin C, in preventing and treating acne vulgaris. The study included a time-kill analysis showing that a 1% SAP formulation reduced the harmful bacteria Propionibacterium acnes by a significant log reduction of 5 after 8 hours. This demonstrates the strong antimicrobial properties of SAP against acne-causing bacteria.
Additionally, we observed an in vivo study with 20 participants, where the SAP formulation effectively prevented up to 40% of UVA-induced sebum oxidation, suggesting it can help reduce inflammation associated with acne. In another open-label study involving 60 volunteers over 12 weeks, a 5% SAP lotion was rated as excellent or good in effectiveness by 76.9% of the participants, outperforming a commonly prescribed acne treatment.
Overall, our findings indicate that sodium ascorbyl phosphate could serve as an effective, non-antibiotic option for both the prevention and treatment of acne, making it an attractive addition to cosmetic products due to its lack of side effects.
Additionally, we observed an in vivo study with 20 participants, where the SAP formulation effectively prevented up to 40% of UVA-induced sebum oxidation, suggesting it can help reduce inflammation associated with acne. In another open-label study involving 60 volunteers over 12 weeks, a 5% SAP lotion was rated as excellent or good in effectiveness by 76.9% of the participants, outperforming a commonly prescribed acne treatment.
Overall, our findings indicate that sodium ascorbyl phosphate could serve as an effective, non-antibiotic option for both the prevention and treatment of acne, making it an attractive addition to cosmetic products due to its lack of side effects.
Read More
1
No significant benefit of vitamin E
Vitamin E does not reduce the side-effects of isotretinoin in the treatment of acne vulgaris.
Highly relevant to vitamin E usage
We explored the effectiveness of vitamin E alongside isotretinoin, a common treatment for severe acne. In an investigator-blinded, randomized study involving 82 patients, participants were divided into two groups. One group received isotretinoin alone, while the other combined it with 800 IU of vitamin E, over a period of 16 weeks.
Our main goal was to determine whether vitamin E could reduce the side-effects associated with isotretinoin, which are often bothersome for patients. Throughout the study, we assessed various mucocutaneous side effects, such as facial dryness and redness, as well as changes in serum lipid and liver enzyme levels.
Ultimately, we found no significant difference in the incidence or severity of side effects between the two treatment groups. This indicates that vitamin E did not provide any noticeable benefit when added to isotretinoin therapy for acne vulgaris.
While vitamin E is often suggested as a remedy to lighten the side effects of medications, our findings suggest that its use alongside isotretinoin may not be helpful.
Our main goal was to determine whether vitamin E could reduce the side-effects associated with isotretinoin, which are often bothersome for patients. Throughout the study, we assessed various mucocutaneous side effects, such as facial dryness and redness, as well as changes in serum lipid and liver enzyme levels.
Ultimately, we found no significant difference in the incidence or severity of side effects between the two treatment groups. This indicates that vitamin E did not provide any noticeable benefit when added to isotretinoin therapy for acne vulgaris.
While vitamin E is often suggested as a remedy to lighten the side effects of medications, our findings suggest that its use alongside isotretinoin may not be helpful.
Read More
Most Useful Reviews
8.8
Skin situation improved
Although I can't definitively claim that this supplement works since my doctor prescribes it, I have been treating my acne with it. After numerous tests, this medication was recommended, and my skin has markedly improved.
Read More
8
Reduces cravings
This remedy effectively normalises blood sugar, curbs food cravings, and assists in fighting acne.
Read More
Medical Researches
SCIENTIFIC SCORE
Questionable
Based on 32 Researches
6.8
- All Researches
9
Vitamin C shows moderate efficacy
Efficacy of tranexamic acid solution versus vitamin C solution after micro-needling in treatment of persistent post acne erythema: a split face clinical and 3DAntera camera comparative study.
Moderate relevance to acne treatment
We explored the effectiveness of using vitamin C in treating persistent post-acne erythema, which often leaves visible redness after acne has cleared. In this study, participants received microneedling combined with either a 10% vitamin C solution or a tranexamic acid solution. The goal was to see which treatment worked better for reducing redness and improving overall skin appearance.
Four treatment sessions were spaced two weeks apart, followed by assessments two weeks after the final session. We measured improvements using clinical evaluations, 3D imaging technology to analyze blood flow in the skin, and patient feedback.
Our findings indicated that both treatments led to significant improvements in reducing skin redness. However, the tranexamic acid solution yielded even better results compared to vitamin C. Patients reported satisfaction on both sides, but they favored the effects of tranexamic acid more. Notably, any side effects were minimal and temporary.
This study suggests that while vitamin C can be helpful, using microneedling with tranexamic acid may deliver superior results for those struggling with post-acne redness.
Four treatment sessions were spaced two weeks apart, followed by assessments two weeks after the final session. We measured improvements using clinical evaluations, 3D imaging technology to analyze blood flow in the skin, and patient feedback.
Our findings indicated that both treatments led to significant improvements in reducing skin redness. However, the tranexamic acid solution yielded even better results compared to vitamin C. Patients reported satisfaction on both sides, but they favored the effects of tranexamic acid more. Notably, any side effects were minimal and temporary.
This study suggests that while vitamin C can be helpful, using microneedling with tranexamic acid may deliver superior results for those struggling with post-acne redness.
Read More
9
Nutraceuticals effective for acne
Cosm-nutraceutical nanovesicles for acne treatment: Physicochemical characterization and exploratory clinical experimentation.
Study shows potential vitamin C benefits
We aimed to understand how a novel formulation combining vitamin C and quercetin can help treat acne. Our study focused on creating small liposomal structures called aspasomes that enhance the delivery of quercetin, a potent antioxidant, onto the skin.
Throughout our research, we thoroughly characterized these aspasomes for their size, stability, and how well they could penetrate the skin. One exciting finding was that these specialized nanovesicles not only preserved the antioxidant benefits of quercetin, but also demonstrated a stronger antibacterial effect against acne-causing bacteria compared to quercetin alone.
In an exploratory clinical trial involving 20 participants with acne, we observed considerable improvements. The results revealed a 77.9% reduction in inflammatory lesions and significant decreases in both non-inflammatory lesions and total acne lesions. These findings suggest that our vitamin C-based formula holds promise in managing acne and could potentially be used for other skin conditions in the future.
Throughout our research, we thoroughly characterized these aspasomes for their size, stability, and how well they could penetrate the skin. One exciting finding was that these specialized nanovesicles not only preserved the antioxidant benefits of quercetin, but also demonstrated a stronger antibacterial effect against acne-causing bacteria compared to quercetin alone.
In an exploratory clinical trial involving 20 participants with acne, we observed considerable improvements. The results revealed a 77.9% reduction in inflammatory lesions and significant decreases in both non-inflammatory lesions and total acne lesions. These findings suggest that our vitamin C-based formula holds promise in managing acne and could potentially be used for other skin conditions in the future.
Read More
9
Vitamin C reduces facial sebum
Assessment of Combined Ascorbyl Palmitate (AP) and Sodium Ascorbyl Phosphate (SAP) on Facial Skin Sebum Control in Female Healthy Volunteers.
Vitamin C's potential impact on acne
We conducted a study to explore the effectiveness of two forms of vitamin C—ascorbyl palmitate (AP) and sodium ascorbyl phosphate (SAP)—in managing sebum production on the skin. Through a single-blinded, placebo-controlled trial involving 11 healthy female volunteers, we compared the effects of a multiple emulsion containing these compounds with a control that lacked them.
Over 90 days, participants applied the vitamin C formulation to one cheek and the control to the other. We measured sebum levels using a non-invasive device called a Sebumeter at different time intervals. Our results demonstrated that the combination of AP and SAP achieved notable antioxidant activity and effectively reduced facial oiliness compared to the control.
Ultimately, we found that incorporating vitamin C into skincare routines can be a promising solution for controlling excess facial sebum, which is often linked to oily skin and acne. However, while the study highlights the role of these antioxidants in sebum regulation, it does not provide a definitive conclusion on their isolated effects solely for acne treatment.
Over 90 days, participants applied the vitamin C formulation to one cheek and the control to the other. We measured sebum levels using a non-invasive device called a Sebumeter at different time intervals. Our results demonstrated that the combination of AP and SAP achieved notable antioxidant activity and effectively reduced facial oiliness compared to the control.
Ultimately, we found that incorporating vitamin C into skincare routines can be a promising solution for controlling excess facial sebum, which is often linked to oily skin and acne. However, while the study highlights the role of these antioxidants in sebum regulation, it does not provide a definitive conclusion on their isolated effects solely for acne treatment.
Read More
9
Zinc ascorbate aids acne treatment
Susceptibility of Propionibacterium acnes isolated from patients with acne vulgaris to zinc ascorbate and antibiotics.
Study shows beneficial combination
We explored the effectiveness of a vitamin C derivative, zinc ascorbate, for treating acne. This study focused on its in vitro antimicrobial activity against Propionibacterium acnes, the bacteria often responsible for acne breakouts.
The researchers tested zinc ascorbate alone and in combination with popular antibiotics like clindamycin, widely used in Japan for acne treatment. They examined how these combinations worked against various strains of P. acnes, including those resistant to clindamycin.
Findings indicated that zinc ascorbate can effectively inhibit the growth of P. acnes, even in clindamycin-resistant strains. Notably, when combined with clindamycin, zinc ascorbate demonstrated an additive effect, enhancing its overall antimicrobial effectiveness.
Overall, this research suggests that incorporating zinc ascorbate could be a promising strategy for acne treatment, especially in conjunction with traditional antibiotics.
The researchers tested zinc ascorbate alone and in combination with popular antibiotics like clindamycin, widely used in Japan for acne treatment. They examined how these combinations worked against various strains of P. acnes, including those resistant to clindamycin.
Findings indicated that zinc ascorbate can effectively inhibit the growth of P. acnes, even in clindamycin-resistant strains. Notably, when combined with clindamycin, zinc ascorbate demonstrated an additive effect, enhancing its overall antimicrobial effectiveness.
Overall, this research suggests that incorporating zinc ascorbate could be a promising strategy for acne treatment, especially in conjunction with traditional antibiotics.
Read More
9
Vitamin C shows effectiveness for acne
Sodium L-ascorbyl-2-phosphate 5% lotion for the treatment of acne vulgaris: a randomized, double-blind, controlled trial.
Direct assessment of vitamin C
In our recent study, we set out to explore the effectiveness of a 5% sodium L-ascorbyl-2-phosphate lotion, a stable form of vitamin C, for treating acne. We conducted a double-blind, controlled trial with 50 participants over 12 weeks, where half used the vitamin C lotion and the other half received a placebo.
Our findings revealed significant improvements in acne symptoms for those using the vitamin C lotion compared to the placebo group. We measured outcomes through various assessments, including a global evaluation by investigators and self-reported assessments by the subjects, along with lesion counts.
The results showed that the vitamin C lotion was not only effective but also well-tolerated, with side effects similar to those seen with the placebo. This adds a promising tool to the options available for acne treatment, suggesting that vitamin C might play a valuable role in skincare regimens aimed at combating acne.
Overall, our study supports the idea that vitamin C, in the form of sodium L-ascorbyl-2-phosphate, can help reduce acne, making it a noteworthy addition to acne treatment strategies.
Our findings revealed significant improvements in acne symptoms for those using the vitamin C lotion compared to the placebo group. We measured outcomes through various assessments, including a global evaluation by investigators and self-reported assessments by the subjects, along with lesion counts.
The results showed that the vitamin C lotion was not only effective but also well-tolerated, with side effects similar to those seen with the placebo. This adds a promising tool to the options available for acne treatment, suggesting that vitamin C might play a valuable role in skincare regimens aimed at combating acne.
Overall, our study supports the idea that vitamin C, in the form of sodium L-ascorbyl-2-phosphate, can help reduce acne, making it a noteworthy addition to acne treatment strategies.
Read More
User Reviews
USERS' SCORE
Good
Based on 2 Reviews
8.5
- All Reviews
- Positive Reviews
- Negative Reviews
8.8
Skin situation improved
Although I can't definitively claim that this supplement works since my doctor prescribes it, I have been treating my acne with it. After numerous tests, this medication was recommended, and my skin has markedly improved.
8
Reduces cravings
This remedy effectively normalises blood sugar, curbs food cravings, and assists in fighting acne.
