Medical Researches
Possibly Effective
Based on 8 Researches
We investigated the relationship between docosahexaenoic acid (DHA), a type of polyunsaturated fatty acid (PUFA), and the occurrence of acne. Using a method called Mendelian randomization, we looked at how genetic variations associated with DHA might influence acne development in large groups of participants, including over 115,000 individuals from the UK and nearly 364,000 of Finnish ancestry.
Our findings revealed that higher levels of DHA are actually linked to a lower risk of developing acne. Specifically, we found that a significant increase in DHA levels or its proportion compared to total fatty acids corresponded with a reduced likelihood of acne. In contrast, higher levels of linoleic acid (LA), another type of PUFA, were associated with an increased acne risk.
This suggests that balancing our intake of these fatty acids might be important for skin health. Notably, the results pointed towards a genetic connection involving the FADS1 gene, which appears to play a role in how these fatty acids affect our skin.
In conclusion, increasing DHA could be beneficial in protecting against acne, while excessive linoleic acid might have the opposite effect. Overall, our study highlights the importance of these fatty acids in understanding acne risk better.
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DHA improves acne severityExploring the potential of omega-3 fatty acids in acne patients: A prospective intervention study.
Strong link between study and findings
We explored the potential benefits of docosahexaenoic acid (DHA), a type of omega-3 fatty acid, in treating acne. Over 16 weeks, 60 participants followed a Mediterranean diet paired with algae-derived DHA and eicosapentaenoic acid (EPA) supplementation. We aimed to boost their omega-3 levels and observe any changes in their acne severity.
Remarkably, our study found that nearly all participants started with a deficiency in omega-3 fatty acids. After the dietary and supplementation intervention, the average omega-3 index rose significantly, indicating improved levels of DHA and EPA. More importantly, participants experienced notable reductions in both inflammatory and non-inflammatory acne lesions.
While a few individuals reported that their skin appearance worsened, the collective quality of life among participants improved, especially for those with papulopustular acne. They also became more aware of dietary triggers and made healthier choices, like reducing cow's milk and dairy intake. Overall, we saw a promising link between increased omega-3 levels and improved acne outcomes.
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Eicosapentaenoic acid helps acneExploring the potential of omega-3 fatty acids in acne patients: A prospective intervention study.
Directly addresses EPA's effects
We focused our research on the potential benefits of eicosapentaenoic acid (EPA), a type of omega-3 fatty acid, for individuals suffering from acne. Over a period of 16 weeks, we encouraged 60 patients to follow a Mediterranean diet while taking algae-derived EPA and docosahexaenoic acid (DHA) supplements. Our goal was to see if increasing their omega-3 levels could improve acne symptoms.
At the start of the study, an impressive 98.3% of the participants were found to have low levels of EPA/DHA. By the end of the study, we observed a significant increase in their omega-3 levels from an average of 4.9% to 8.3%. This boost correlated with noticeable improvements in both inflammatory and non-inflammatory acne lesions.
Interestingly, we noted that while individual perceptions of appearance varied—some reporting no improvement—overall quality of life for the participants enhanced significantly, particularly in those with papulopustular acne. Alongside dietary changes, participants reduced their intake of cow’s milk and dairy products, and we did not encounter any negative side effects from the intervention.
Ultimately, our findings suggest that boosting omega-3 fatty acids, particularly EPA, through diet and supplementation can effectively help manage acne severity in patients.
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Docosahexaenoic acid aids acne treatmentEffect of dietary supplementation with omega-3 fatty acid and gamma-linolenic acid on acne vulgaris: a randomised, double-blind, controlled trial.
Valuable treatment insights shared
We conducted an interesting study to understand how docosahexaenoic acid (a type of omega-3 fatty acid) influences acne treatment. Over 10 weeks, 45 participants with mild to moderate acne were divided into three groups: one receiving omega-3 fatty acids, another taking gamma-linoleic acid, and a control group.
Remarkably, those who received omega-3 and gamma-linoleic acid experienced significant reductions in both inflammatory and non-inflammatory acne lesions. This improvement was reflected in participants’ personal assessments, highlighting their positive experiences with the treatment.
Additionally, we observed that laboratory tests showed decreased inflammation and a reduction in levels of interleukin-8, a marker linked to acne inflammation. Importantly, there were no serious side effects reported, which is encouraging for considering these supplements as adjunct treatments for acne.
Overall, our findings suggest that incorporating omega-3 fatty acids, like docosahexaenoic acid, may be beneficial for individuals struggling with acne, providing a natural option alongside conventional treatments.
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Omega-3s beneficial for acneEffect of dietary supplementation with omega-3 fatty acid and gamma-linolenic acid on acne vulgaris: a randomised, double-blind, controlled trial.
Strong relevance to eicosapentaenoic acid
We explored the potential of eicosapentaenoic acid, a key omega-3 fatty acid, in treating acne vulgaris through a structured study involving 45 participants with mild to moderate acne. Over ten weeks, participants were divided into three groups: one received 2,000 mg of eicosapentaenoic acid with docosahexaenoic acid, another got 400 mg of gamma-linolenic acid from borage oil, and a control group received no supplements.
After this supplementation period, we observed notable reductions in both inflammatory and non-inflammatory acne lesions in participants taking either the omega-3 or gamma-linolenic acid. The participants also reported improvements based on their personal assessments. Furthermore, histological examinations showed decreased inflammation and lower levels of interleukin-8, a marker related to acne inflammation.
Importantly, no severe adverse effects were reported, indicating that these fatty acids could be safely used alongside traditional acne treatments. Overall, this research suggests that eicosapentaenoic acid and gamma-linolenic acid may serve as valuable additions to acne management strategies.
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User Reviews
I've been using this for three years now. My nails are less brittle, bruises fewer, and my skin is smoother, with peeling and acne now gone. I take three capsules daily and will keep using it.
A beautiful product that diminishes acne and makes my skin bright and lovely.
My skin feels hydrated and nearly free of acne after six months of use. I will definitely order more.
The quality of the fish oil is excellent, and I noticed benefits quite quickly. Having struggled with dry skin and acne for 30 years, I realised I needed a good DHA supplement. After about a month, my skin improved significantly, reducing my lotion use, and I experience no fishy burps with this easy-to-swallow tablet.
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After taking it daily for a month, my skin looks less inflamed and red, with no new acne spots. The capsules are quite large, but I managed to take them without any issue. There was no aftertaste.