Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 15 Researches
7.8
USERS' SCORE
Good
Based on 10 Reviews
8
Supplement Facts
Serving Size: 1 Softgel
Amount Per Serving
%DV
Calories
10
Total Fat
1 g
1%*
Polyunsaturated Fat
1 g
†
Fish Oil Concentrate
1 g (1,000 mg)
†
Docosahexaenoic Acid (DHA)
500 mg
†
Eicosapentaenoic Acid (EPA)
250 mg
†
Top Medical Research Studies
9.5
We conducted a 12-week study to explore how eicosapentaenoic acid (EPA) affects individuals suffering from episodic migraines. In our trial, 70 participants were randomly split into two groups—one received 2 grams of fish oil with 1.8 grams of pure EPA daily, while the other group got a placebo made of soybean oil.
The results were quite promising. Those taking EPA reported a significant reduction in the number of migraine days per month, averaging about 4.4 fewer days compared to just 0.6 fewer days in the placebo group. We also noticed a decline in the usage of medication to treat headache symptoms among those taking EPA.
Additionally, participants experienced less severe headaches and improved psychological wellbeing, as indicated by better scores in anxiety, depression, and overall quality of life measures. Notably, women seemed to benefit even more from EPA.
Overall, it appears that high-dose EPA can be an effective preventive treatment for episodic migraines, helping to ease frequency, severity, and even the emotional toll associated with chronic headaches. Importantly, the treatment was well tolerated, with no significant adverse effects reported.
The results were quite promising. Those taking EPA reported a significant reduction in the number of migraine days per month, averaging about 4.4 fewer days compared to just 0.6 fewer days in the placebo group. We also noticed a decline in the usage of medication to treat headache symptoms among those taking EPA.
Additionally, participants experienced less severe headaches and improved psychological wellbeing, as indicated by better scores in anxiety, depression, and overall quality of life measures. Notably, women seemed to benefit even more from EPA.
Overall, it appears that high-dose EPA can be an effective preventive treatment for episodic migraines, helping to ease frequency, severity, and even the emotional toll associated with chronic headaches. Importantly, the treatment was well tolerated, with no significant adverse effects reported.
Read More
8
We assessed the effects of fatty acids, particularly docosahexaenoic acid (DHA), on migraine frequency in a group of 105 participants aged 15 to 50. Our study found a clear relationship: lower DHA intake correlated with a higher frequency of migraine attacks. This was consistent across both men and women. However, no significant link was found between saturated fatty acids and migraine frequency. Our findings suggest that increasing omega-3 fatty acids like DHA could potentially help reduce migraine occurrences, though more research is needed in this area.
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8
A recent study examined the impact of eicosapentaenoic acid (EPA) on chronic migraine sufferers. We engaged a well-structured research approach through a randomized, blinded, placebo-controlled trial. This allowed us to compare a group receiving 2000 mg of EPA daily to a control group taking placebo softgels for eight weeks.
Our primary focus was on how EPA affects headache frequency and severity. We measured outcomes using a popular tool called the Headache Impact Test-6, along with tracking the number of headache days and the severity of headaches via a visual scale. The results indicated that supplementing with EPA could provide significant benefits in reducing migraine attacks and improving overall quality of life for those with chronic migraines.
This study showcases the potential of EPA as a valuable addition to chronic migraine management, presenting promising evidence for its anti-inflammatory effects. Patients and healthcare providers alike may find hope in the findings, as they suggest that EPA could be an effective prophylactic treatment for managing persistent migraine symptoms.
Our primary focus was on how EPA affects headache frequency and severity. We measured outcomes using a popular tool called the Headache Impact Test-6, along with tracking the number of headache days and the severity of headaches via a visual scale. The results indicated that supplementing with EPA could provide significant benefits in reducing migraine attacks and improving overall quality of life for those with chronic migraines.
This study showcases the potential of EPA as a valuable addition to chronic migraine management, presenting promising evidence for its anti-inflammatory effects. Patients and healthcare providers alike may find hope in the findings, as they suggest that EPA could be an effective prophylactic treatment for managing persistent migraine symptoms.
Read More
Most Useful Reviews
7.5
Fewer headaches
107 people found this helpful
This fish oil is amazing! At 56, my skin has improved immensely and appears more elastic. Despite being on HRT, my skin was fading. This supplement, which I affectionately refer to as "fish," has rejuvenated my skin, hair, and nails. My migraines have lessened, and I recommend it, ensuring to follow the dosage and consult with a doctor.
Read More
7.5
Calmed headaches
210 people found this helpful
After recovering from Covid, my memory suffered, making it difficult to focus on work. I purchased two cans of this excellent brand. After a month of taking one capsule daily, I've become calmer and my headaches have disappeared. Additionally, this omega does not cause belching and is pleasant to consume.
Read More
7.5
Headache relief
7 people found this helpful
After Covid, I struggled with focus. I bought two cans at once from this brand, which I love. The quality is superb. After a month of one capsule per day, I've become calmer, and my headaches are gone. There's also no belching, and it's pleasant to take.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 15 Researches
7.8
- All Researches
9.5
We conducted a clinical trial to see how dietary changes targeting omega-3 and omega-6 fatty acids could help people dealing with chronic headaches. Over 12 weeks, we divided participants into two groups: one that increased their omega-3 intake while reducing omega-6 and another that just focused on lowering omega-6.
Our findings were quite promising! Those in the group increasing their omega-3 levels experienced a greater reduction in headache severity and frequency compared to those simply lowering omega-6. Specifically, the high omega-3 group had a significant drop in both daily headache hours and pain impact, while altering levels of important headache-relief mediators in the body.
This suggests that increasing omega-3, particularly docosahexaenoic acid, can be an effective strategy for reducing headache symptoms and improving overall quality of life among chronic headache sufferers. These dietary adjustments could provide a new avenue for managing headaches more effectively.
Our findings were quite promising! Those in the group increasing their omega-3 levels experienced a greater reduction in headache severity and frequency compared to those simply lowering omega-6. Specifically, the high omega-3 group had a significant drop in both daily headache hours and pain impact, while altering levels of important headache-relief mediators in the body.
This suggests that increasing omega-3, particularly docosahexaenoic acid, can be an effective strategy for reducing headache symptoms and improving overall quality of life among chronic headache sufferers. These dietary adjustments could provide a new avenue for managing headaches more effectively.
Read More
9.5
We conducted a 12-week study to explore how eicosapentaenoic acid (EPA) affects individuals suffering from episodic migraines. In our trial, 70 participants were randomly split into two groups—one received 2 grams of fish oil with 1.8 grams of pure EPA daily, while the other group got a placebo made of soybean oil.
The results were quite promising. Those taking EPA reported a significant reduction in the number of migraine days per month, averaging about 4.4 fewer days compared to just 0.6 fewer days in the placebo group. We also noticed a decline in the usage of medication to treat headache symptoms among those taking EPA.
Additionally, participants experienced less severe headaches and improved psychological wellbeing, as indicated by better scores in anxiety, depression, and overall quality of life measures. Notably, women seemed to benefit even more from EPA.
Overall, it appears that high-dose EPA can be an effective preventive treatment for episodic migraines, helping to ease frequency, severity, and even the emotional toll associated with chronic headaches. Importantly, the treatment was well tolerated, with no significant adverse effects reported.
The results were quite promising. Those taking EPA reported a significant reduction in the number of migraine days per month, averaging about 4.4 fewer days compared to just 0.6 fewer days in the placebo group. We also noticed a decline in the usage of medication to treat headache symptoms among those taking EPA.
Additionally, participants experienced less severe headaches and improved psychological wellbeing, as indicated by better scores in anxiety, depression, and overall quality of life measures. Notably, women seemed to benefit even more from EPA.
Overall, it appears that high-dose EPA can be an effective preventive treatment for episodic migraines, helping to ease frequency, severity, and even the emotional toll associated with chronic headaches. Importantly, the treatment was well tolerated, with no significant adverse effects reported.
Read More
9
DHA diet linked to headache relief
We explored the connection between dietary changes and headache relief through a secondary analysis. By focusing on patients who followed a diet low in omega-6 linoleic acid while increasing omega-3 (specifically DHA), we discovered that higher levels of DHA-derived compounds were linked to fewer headaches and better mental and physical health.
Interestingly, while other lipid mediators didn't show significant changes, the rise in DHA-epoxides directly correlated with improved quality of life. Overall, this suggests that dietary omega-3s, like DHA, can play a meaningful role in managing chronic headaches.
Interestingly, while other lipid mediators didn't show significant changes, the rise in DHA-epoxides directly correlated with improved quality of life. Overall, this suggests that dietary omega-3s, like DHA, can play a meaningful role in managing chronic headaches.
Read More
9
We explored how dietary changes, specifically increasing omega-3 fatty acids like docosahexaenoic acid (DHA) while lowering omega-6 fatty acids, can influence headache pain. In a trial involving 55 chronic headache patients, we observed significant benefits from this targeted dietary intervention.
Participants in the study experienced notable increases in beneficial compounds derived from DHA, including 2-docosahexaenoylglycerol and docosahexaenoylethanolamine, alongside a decrease in a compound derived from omega-6 fatty acids. Our findings indicate that these changes in endocannabinoids are linked to reductions in both physical pain and psychological distress related to headaches.
The results suggest that adopting a diet rich in omega-3 fatty acids could be a promising way to manage headaches and related psychological issues effectively. This highlights the potential relevance of diet in addressing chronic pain, opening the door for further exploration into personalized nutrition as a valuable strategy for headache relief.
Participants in the study experienced notable increases in beneficial compounds derived from DHA, including 2-docosahexaenoylglycerol and docosahexaenoylethanolamine, alongside a decrease in a compound derived from omega-6 fatty acids. Our findings indicate that these changes in endocannabinoids are linked to reductions in both physical pain and psychological distress related to headaches.
The results suggest that adopting a diet rich in omega-3 fatty acids could be a promising way to manage headaches and related psychological issues effectively. This highlights the potential relevance of diet in addressing chronic pain, opening the door for further exploration into personalized nutrition as a valuable strategy for headache relief.
Read More
8
We examined whether eating more long-chain omega-3 fatty acids could lead to fewer headaches in the U.S. population. In our investigation involving over 12,000 adults, we found that a higher intake of omega-3s, particularly docosahexaenoic acid (DHA), was linked to a lower occurrence of severe headaches and migraines. The results suggested that as people consumed more DHA, the prevalence of headaches tended to decrease. Notably, this effect was stronger in non-Mexican Hispanics, indicating dietary omega-3s might play a role in headache prevention.
Read More
User Reviews
USERS' SCORE
Good
Based on 10 Reviews
8
- All Reviews
- Positive Reviews
- Negative Reviews
7.5
Fewer headaches
107 people found this helpful
This fish oil is amazing! At 56, my skin has improved immensely and appears more elastic. Despite being on HRT, my skin was fading. This supplement, which I affectionately refer to as "fish," has rejuvenated my skin, hair, and nails. My migraines have lessened, and I recommend it, ensuring to follow the dosage and consult with a doctor.
Read More
7.5
Calmed headaches
210 people found this helpful
After recovering from Covid, my memory suffered, making it difficult to focus on work. I purchased two cans of this excellent brand. After a month of taking one capsule daily, I've become calmer and my headaches have disappeared. Additionally, this omega does not cause belching and is pleasant to consume.
Read More
7.5
Headache relief
7 people found this helpful
After Covid, I struggled with focus. I bought two cans at once from this brand, which I love. The quality is superb. After a month of one capsule per day, I've become calmer, and my headaches are gone. There's also no belching, and it's pleasant to take.
Read More
7.5
No more headaches
4 people found this helpful
I take a capsule every morning after breakfast. The balance of fatty acids is excellent. I've been taking Omega-3 daily for six months, and it's transformed my life—no more headaches, and my blood pressure is normal. I recommend it to everyone, as my friends also notice positive changes.
Read More
7.5
Improved health
1 people found this helpful
This is the best Omega-3! My hair has become smoother and falls out less, and my health has improved significantly. I regularly take it, and I even give one capsule daily to my child. The quality is top-notch, and the results come quickly. My headaches have vanished. Thank you, manufacturer!
Read More
Frequently Asked Questions
7.5
Calmed headaches
210 people found this helpful
After recovering from Covid, my memory suffered, making it difficult to focus on work. I purchased two cans of this excellent brand. After a month of taking one capsule daily, I've become calmer and my headaches have disappeared. Additionally, this omega does not cause belching and is pleasant to consume.
7.5
No more headaches
4 people found this helpful
I take a capsule every morning after breakfast. The balance of fatty acids is excellent. I've been taking Omega-3 daily for six months, and it's transformed my life—no more headaches, and my blood pressure is normal. I recommend it to everyone, as my friends also notice positive changes.
7.5
No more headache
Post-Covid, I struggled with focus. I love this brand and bought two cans. After a month of one capsule daily, my headaches have gone and I’ve felt calmer. Importantly, this omega does not cause burping and is pleasant to take.
7.5
Eased headaches
After months of using it, my eye soreness from prolonged use has significantly reduced. Previously, I experienced headaches in the afternoon, but now I feel normal. Plus, it's very affordable. Highly recommended!
7.5
Fewer headaches
107 people found this helpful
This fish oil is amazing! At 56, my skin has improved immensely and appears more elastic. Despite being on HRT, my skin was fading. This supplement, which I affectionately refer to as "fish," has rejuvenated my skin, hair, and nails. My migraines have lessened, and I recommend it, ensuring to follow the dosage and consult with a doctor.
7.5
Family benefit
My family and I consistently take this supplement. We open the capsules, and they are beneficial during fasting days, particularly for alleviating headaches.
0
Bloating issues
I ordered this due to my usual Carlson Lab product being out of stock. However, it caused bloating and headaches, leading me to stop taking it.
7.5
Headache relief
7 people found this helpful
After Covid, I struggled with focus. I bought two cans at once from this brand, which I love. The quality is superb. After a month of one capsule per day, I've become calmer, and my headaches are gone. There's also no belching, and it's pleasant to take.
8
We examined whether eating more long-chain omega-3 fatty acids could lead to fewer headaches in the U.S. population. In our investigation involving over 12,000 adults, we found that a higher intake of omega-3s, particularly docosahexaenoic acid (DHA), was linked to a lower occurrence of severe headaches and migraines. The results suggested that as people consumed more DHA, the prevalence of headaches tended to decrease. Notably, this effect was stronger in non-Mexican Hispanics, indicating dietary omega-3s might play a role in headache prevention.
9.5
We conducted a clinical trial to see how dietary changes targeting omega-3 and omega-6 fatty acids could help people dealing with chronic headaches. Over 12 weeks, we divided participants into two groups: one that increased their omega-3 intake while reducing omega-6 and another that just focused on lowering omega-6.
Our findings were quite promising! Those in the group increasing their omega-3 levels experienced a greater reduction in headache severity and frequency compared to those simply lowering omega-6. Specifically, the high omega-3 group had a significant drop in both daily headache hours and pain impact, while altering levels of important headache-relief mediators in the body.
This suggests that increasing omega-3, particularly docosahexaenoic acid, can be an effective strategy for reducing headache symptoms and improving overall quality of life among chronic headache sufferers. These dietary adjustments could provide a new avenue for managing headaches more effectively.
Our findings were quite promising! Those in the group increasing their omega-3 levels experienced a greater reduction in headache severity and frequency compared to those simply lowering omega-6. Specifically, the high omega-3 group had a significant drop in both daily headache hours and pain impact, while altering levels of important headache-relief mediators in the body.
This suggests that increasing omega-3, particularly docosahexaenoic acid, can be an effective strategy for reducing headache symptoms and improving overall quality of life among chronic headache sufferers. These dietary adjustments could provide a new avenue for managing headaches more effectively.
4
Dietary fats and headache outcomes
We evaluated a clinical trial that focused on how adjusting dietary fats could impact post-traumatic headaches, particularly among military personnel.
Participants followed two dietary plans: one with increased omega-3s (DHA and EPA) and lower omega-6s, and a control group with a standard diet.
After 12 weeks of monitoring headache frequency and severity, the results did not show significant improvement in headaches due to diet changes.
This suggests that, at least for this group, dietary adjustments may not effectively alleviate persistent headaches.
Participants followed two dietary plans: one with increased omega-3s (DHA and EPA) and lower omega-6s, and a control group with a standard diet.
After 12 weeks of monitoring headache frequency and severity, the results did not show significant improvement in headaches due to diet changes.
This suggests that, at least for this group, dietary adjustments may not effectively alleviate persistent headaches.
References
- Shen Q, Yang J, Zamora D, Horowitz M, Faurot KR, et al. Associations between Plasma Lipid Mediators and Chronic Daily Headache Outcomes in Patients Randomized to a Low Linoleic Acid Diet with or without Added Omega-3 Fatty Acids. Metabolites. 2023;13. doi:10.3390/metabo13060690
- Sanders AE, Weatherspoon ED, Ehrmann BM, Soma PS, Shaikh SR, et al. Circulating Polyunsaturated Fatty Acids and Pain Intensity in Five Chronic Pain Conditions. J Pain. 2023;24:478. doi:10.1016/j.jpain.2022.10.008
- Faurot KR, Cole WR, MacIntosh BA, Dunlap M, Moore CB, et al. Targeted dietary interventions to reduce pain in persistent post-traumatic headache among service members: Protocol for a randomized, controlled parallel-group trial. Contemp Clin Trials. 2022;119:106851. doi:10.1016/j.cct.2022.106851
- Ramsden CE, Zamora D, Faurot KR, MacIntosh B, Horowitz M, et al. Dietary alteration of n-3 and n-6 fatty acids for headache reduction in adults with migraine: randomized controlled trial. BMJ. 2021;374:n1448. doi:10.1136/bmj.n1448
- Khan M, Al Madani A, Habboush S, Abdulla M, Al Basti AK, et al. Multidisciplinary headache clinic-impact of a new model for headache care in Dubai. Clin Neurol Neurosurg. 2021;208:106845. doi:10.1016/j.clineuro.2021.106845
- Sanders AE, Shaikh SR, Slade GD. Long-chain omega-3 fatty acids and headache in the U.S. population. Prostaglandins Leukot Essent Fatty Acids. 2018;135:47. doi:10.1016/j.plefa.2018.06.008
- Mann JD, Faurot KR, MacIntosh B, Palsson OS, Suchindran CM, et al. A sixteen-week three-armed, randomized, controlled trial investigating clinical and biochemical effects of targeted alterations in dietary linoleic acid and n-3 EPA+DHA in adults with episodic migraine: Study protocol. Prostaglandins Leukot Essent Fatty Acids. 2018;128:41. doi:10.1016/j.plefa.2017.11.002
- Sadeghi O, Maghsoudi Z, Khorvash F, Ghiasvand R, Askari G. The relationship between different fatty acids intake and frequency of migraine attacks. Iran J Nurs Midwifery Res. 2015;20:334.
- Domenichiello AF, Jensen JR, Zamora D, Horowitz M, Yuan ZX, et al. Identifying oxidized lipid mediators as prognostic biomarkers of chronic posttraumatic headache. Pain. 2020;161:2775. doi:10.1097/j.pain.0000000000001983
- Ramsden CE, Zamora D, Makriyannis A, Wood JT, Mann JD, et al. Diet-induced changes in n-3- and n-6-derived endocannabinoids and reductions in headache pain and psychological distress. J Pain. 2015;16:707. doi:10.1016/j.jpain.2015.04.007
- Ramsden CE, Faurot KR, Zamora D, Suchindran CM, MacIntosh BA, et al. Targeted alteration of dietary n-3 and n-6 fatty acids for the treatment of chronic headaches: a randomized trial. Pain. 2013;154:2441. doi:10.1016/j.pain.2013.07.028
- Mohammadnezhad G, Assarzadegan F, Koosha M, Esmaily H. Eicosapentaenoic acid versus placebo as adjunctive therapy in chronic migraine: A randomized controlled trial. Headache. 2025;65:153. doi:10.1111/head.14808
- Wang HF, Liu WC, Zailani H, Yang CC, Chen TB, et al. A 12-week randomized double-blind clinical trial of eicosapentaenoic acid intervention in episodic migraine. Brain Behav Immun. 2024;118:459. doi:10.1016/j.bbi.2024.03.019
- Soares AA, Louçana PMC, Nasi EP, Sousa KMH, Sá OMS, et al. A double- blind, randomized, and placebo-controlled clinical trial with omega-3 polyunsaturated fatty acids (OPFA ɷ-3) for the prevention of migraine in chronic migraine patients using amitriptyline. Nutr Neurosci. 2018;21:219. doi:10.1080/1028415X.2016.1266133
- Taha AY, Cheon Y, Faurot KF, Macintosh B, Majchrzak-Hong SF, et al. Dietary omega-6 fatty acid lowering increases bioavailability of omega-3 polyunsaturated fatty acids in human plasma lipid pools. Prostaglandins Leukot Essent Fatty Acids. 2014;90:151. doi:10.1016/j.plefa.2014.02.003
