Reviewed By
Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 23 Researches
7.7
USERS' SCORE
Good
Based on 8 Reviews
8.1
Supplement Facts
Serving Size: 1 Softgel
Amount Per Serving
%DV
Calories
10
Total Fat
1 g
1%*
Polyunsaturated Fat
1 g
†
Fish Oil Concentrate
1 g (1,000 mg)
†
Docosahexaenoic Acid (DHA)
500 mg
†
Eicosapentaenoic Acid (EPA)
250 mg
†
Top Medical Research Studies
9
DHA lowers cholesterol; boosts metabolism
We aimed to investigate how docosahexaenoic acid (DHA) impacts cholesterol levels and brain glucose metabolism. In our study, we focused on aged SAMP8 mice, dividing them into two groups: a control group and one receiving DHA supplementation.
Our results revealed encouraging changes; the group that received DHA showed a decrease in total cholesterol and low-density lipoprotein cholesterol, while high-density lipoprotein cholesterol levels increased. More importantly, we observed improvements in glucose metabolism in various brain regions, including the cortex and hippocampus.
These findings suggest that DHA may help lower harmful cholesterol levels and enhance brain function by regulating specific cholesterol compounds like 27-hydroxycholesterol, which are linked to glucose metabolism. Overall, our study highlights DHA's potential in supporting heart and brain health through cholesterol management.
Our results revealed encouraging changes; the group that received DHA showed a decrease in total cholesterol and low-density lipoprotein cholesterol, while high-density lipoprotein cholesterol levels increased. More importantly, we observed improvements in glucose metabolism in various brain regions, including the cortex and hippocampus.
These findings suggest that DHA may help lower harmful cholesterol levels and enhance brain function by regulating specific cholesterol compounds like 27-hydroxycholesterol, which are linked to glucose metabolism. Overall, our study highlights DHA's potential in supporting heart and brain health through cholesterol management.
Read More
9
Eicosapentaenoic acid benefits cholesterol
We explored the effects of eicosapentaenoic acid (EPA), a specific type of omega-3 fatty acid, on cholesterol levels in a recent study involving real-world supplement consumers. Participants took AlmegaPL capsules, which contain high amounts of EPA and are free of the other omega-3 fatty acid, DHA. This setup allowed us to gain insights from those who are already incorporating EPA into their diets.
Throughout the study, we monitored key health markers such as triglycerides, total cholesterol, and various types of cholesterol at different stages of supplementation. We observed that after six months of taking this supplement, participants showed a significant reduction in remnant cholesterol and maintained healthy triglyceride levels. Notably, this decrease in cholesterol did not come at the expense of raising low-density lipoprotein (LDL) levels, which is often a concern with other treatments.
These encouraging results reveal that EPA can be a beneficial addition for individuals looking to manage their cholesterol levels effectively. Importantly, our findings highlight AlmegaPL's unique position as a natural, over-the-counter option for those seeking to improve their lipid profiles.
Throughout the study, we monitored key health markers such as triglycerides, total cholesterol, and various types of cholesterol at different stages of supplementation. We observed that after six months of taking this supplement, participants showed a significant reduction in remnant cholesterol and maintained healthy triglyceride levels. Notably, this decrease in cholesterol did not come at the expense of raising low-density lipoprotein (LDL) levels, which is often a concern with other treatments.
These encouraging results reveal that EPA can be a beneficial addition for individuals looking to manage their cholesterol levels effectively. Importantly, our findings highlight AlmegaPL's unique position as a natural, over-the-counter option for those seeking to improve their lipid profiles.
Read More
7
We aimed to understand whether docosahexaenoic acid (DHA), a key component of fish oil, has a positive impact on cholesterol levels, specifically by examining its effects on high-density lipoprotein (HDL). In our study, seven healthy individuals who had never taken fish oil before consumed daily supplements containing 1125 mg of EPA and 875 mg of DHA for 30 days. After a washout period, during which they stopped taking the supplements, we assessed changes in HDL functionality and composition.
Our results indicated that fish oil supplementation led to significant modifications in the proteins and lipid content of HDL. Notably, there was an increase in beneficial phospholipid families, such as sphingomyelins and phosphatidylcholines, which are crucial for HDL's role in cholesterol transport. We found that the capacity of HDL to efflux cholesterol, which is essential for heart health, increased after taking fish oil.
Additionally, improvements in HDL cholesterol efflux capacity were correlated with higher levels of EPA in the participants' blood. These findings suggest that DHA, through its role in fish oil, enhances HDL's ability to remove cholesterol, potentially offering cardiovascular benefits. Overall, our study highlights the transformative effects of fish oil on HDL and its cholesterol management capabilities.
Our results indicated that fish oil supplementation led to significant modifications in the proteins and lipid content of HDL. Notably, there was an increase in beneficial phospholipid families, such as sphingomyelins and phosphatidylcholines, which are crucial for HDL's role in cholesterol transport. We found that the capacity of HDL to efflux cholesterol, which is essential for heart health, increased after taking fish oil.
Additionally, improvements in HDL cholesterol efflux capacity were correlated with higher levels of EPA in the participants' blood. These findings suggest that DHA, through its role in fish oil, enhances HDL's ability to remove cholesterol, potentially offering cardiovascular benefits. Overall, our study highlights the transformative effects of fish oil on HDL and its cholesterol management capabilities.
Read More
Most Useful Reviews
7.5
Cholesterol reduction success
350 people found this helpful
OMEGA-3 Double Strength has a notable DHA content, perfect for those seeking to lower high cholesterol. Its unique ratio of DHA to EPA, at 2:1, makes it stand out. I noticed improvements in my skin, hair, and dry eyes. My husband, who struggled with high cholesterol, saw positive results after two and a half months of taking Omega-3 alongside lecithin. It's essential to monitor both good and bad cholesterol levels during tests. My cat loves it too, and I believe it benefits her health as well.
Read More
9
Improved cholesterol levels
211 people found this helpful
Omega 3 lowers cholesterol, reduces inflammation, and enhances skin and hair quality. Despite the fishy taste, the quality suits me fine. Although prices have surged due to currency fluctuations, investing in health is essential. We take it as a family, and the large packaging accommodates everyone.
Read More
8
Skin condition improvement
196 people found this helpful
This omega 3 is of high quality and comes in an ideal dosage. I consume two capsules during lunch and have noticed less dry skin. Overall, I've experienced significant benefits from taking omega, and I highly recommend it.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 23 Researches
7.7
- All Researches
9
We explored how Antarctic krill oil, particularly its key components like docosahexaenoic acid (DHA), can combat high cholesterol and obesity-related issues. Our study focused on its effects in a controlled environment using obese mice that were fed a high-fat diet.
We observed that when these mice were supplemented with krill oil, there were notable reductions in cholesterol levels and fat accumulation. It seemed to positively influence various metabolic pathways, such as those associated with cholesterol metabolism.
Specifically, DHA, along with other nutrients found in krill oil, appears to aid in lowering oxidative stress and improving cholesterol metabolism. While the benefits of DHA alone weren't isolated in this study, the overall findings suggest that krill oil may work effectively in reducing the risks tied to obesity and high cholesterol.
Overall, this research indicates that incorporating krill oil into our diets could be a promising strategy for managing cholesterol levels and supporting heart health.
We observed that when these mice were supplemented with krill oil, there were notable reductions in cholesterol levels and fat accumulation. It seemed to positively influence various metabolic pathways, such as those associated with cholesterol metabolism.
Specifically, DHA, along with other nutrients found in krill oil, appears to aid in lowering oxidative stress and improving cholesterol metabolism. While the benefits of DHA alone weren't isolated in this study, the overall findings suggest that krill oil may work effectively in reducing the risks tied to obesity and high cholesterol.
Overall, this research indicates that incorporating krill oil into our diets could be a promising strategy for managing cholesterol levels and supporting heart health.
Read More
9
DHA supplementation for cholesterol management
We explored how docosahexaenoic acid (DHA), a type of omega-3 fatty acid, influences levels of bad cholesterol and related diabetes risk. In a comprehensive study, participants were given a daily supplement of both EPA and DHA for twelve weeks. This supplementation aimed to see if it could counteract the negative effects of low-density lipoproteins (LDL) on human adipose tissue.
The results were quite revealing. Before the intervention, we noticed a significant difference in interleukin-1 beta (IL-1β) secretion, a pro-inflammatory substance linked to higher cholesterol levels, between individuals with high and low levels of atherogenic lipoproteins (apoB). After the supplementation with EPA and DHA, this inflammatory response was significantly reduced in those with high apoB. Not only did the fatty acids inhibit IL-1β secretion triggered by LDL, but they also improved fat metabolism and insulin response.
Furthermore, we observed that the omega-3 supplementation addressed various cardiometabolic risk factors, including those related to adiposity. The study indicated that DHA, alongside EPA, plays a role in managing inflammatory responses that contribute to high cholesterol levels and diabetes risk.
In conclusion, incorporating DHA as part of omega-3 supplementation could be a valuable strategy for those with elevated cholesterol levels, especially in preventing type 2 diabetes and its associated health issues.
The results were quite revealing. Before the intervention, we noticed a significant difference in interleukin-1 beta (IL-1β) secretion, a pro-inflammatory substance linked to higher cholesterol levels, between individuals with high and low levels of atherogenic lipoproteins (apoB). After the supplementation with EPA and DHA, this inflammatory response was significantly reduced in those with high apoB. Not only did the fatty acids inhibit IL-1β secretion triggered by LDL, but they also improved fat metabolism and insulin response.
Furthermore, we observed that the omega-3 supplementation addressed various cardiometabolic risk factors, including those related to adiposity. The study indicated that DHA, alongside EPA, plays a role in managing inflammatory responses that contribute to high cholesterol levels and diabetes risk.
In conclusion, incorporating DHA as part of omega-3 supplementation could be a valuable strategy for those with elevated cholesterol levels, especially in preventing type 2 diabetes and its associated health issues.
Read More
9
DHA lowers cholesterol; boosts metabolism
We aimed to investigate how docosahexaenoic acid (DHA) impacts cholesterol levels and brain glucose metabolism. In our study, we focused on aged SAMP8 mice, dividing them into two groups: a control group and one receiving DHA supplementation.
Our results revealed encouraging changes; the group that received DHA showed a decrease in total cholesterol and low-density lipoprotein cholesterol, while high-density lipoprotein cholesterol levels increased. More importantly, we observed improvements in glucose metabolism in various brain regions, including the cortex and hippocampus.
These findings suggest that DHA may help lower harmful cholesterol levels and enhance brain function by regulating specific cholesterol compounds like 27-hydroxycholesterol, which are linked to glucose metabolism. Overall, our study highlights DHA's potential in supporting heart and brain health through cholesterol management.
Our results revealed encouraging changes; the group that received DHA showed a decrease in total cholesterol and low-density lipoprotein cholesterol, while high-density lipoprotein cholesterol levels increased. More importantly, we observed improvements in glucose metabolism in various brain regions, including the cortex and hippocampus.
These findings suggest that DHA may help lower harmful cholesterol levels and enhance brain function by regulating specific cholesterol compounds like 27-hydroxycholesterol, which are linked to glucose metabolism. Overall, our study highlights DHA's potential in supporting heart and brain health through cholesterol management.
Read More
9
We examined the impact of a highly purified eicosapentaenoic acid (EPA) formulation on cholesterol levels and overall heart health in individuals considered at high risk for cardiovascular issues. The study involved 226 patients who had high triglycerides and one or more cardiovascular risk factors, such as hypertension or diabetes.
Participants received 4 grams of EPA daily for three months alongside regular nutritional counseling. By tracking key health markers, we noted significant improvements in cholesterol levels, particularly in triglycerides and low-density lipoprotein (LDL). For instance, triglyceride levels dropped from an average of 2.97 mmol/L to 1.75 mmol/L in just three months.
Additionally, we found improvements in other important metrics, including total cholesterol and glucose levels, indicating that EPA supplementation may have broad benefits for cardiometabolic health. Although apolipoprotein A levels did not change significantly, the overall trend suggests that incorporating EPA could play a role in achieving better heart health outcomes.
Participants received 4 grams of EPA daily for three months alongside regular nutritional counseling. By tracking key health markers, we noted significant improvements in cholesterol levels, particularly in triglycerides and low-density lipoprotein (LDL). For instance, triglyceride levels dropped from an average of 2.97 mmol/L to 1.75 mmol/L in just three months.
Additionally, we found improvements in other important metrics, including total cholesterol and glucose levels, indicating that EPA supplementation may have broad benefits for cardiometabolic health. Although apolipoprotein A levels did not change significantly, the overall trend suggests that incorporating EPA could play a role in achieving better heart health outcomes.
Read More
9
Eicosapentaenoic acid benefits cholesterol
We explored the effects of eicosapentaenoic acid (EPA), a specific type of omega-3 fatty acid, on cholesterol levels in a recent study involving real-world supplement consumers. Participants took AlmegaPL capsules, which contain high amounts of EPA and are free of the other omega-3 fatty acid, DHA. This setup allowed us to gain insights from those who are already incorporating EPA into their diets.
Throughout the study, we monitored key health markers such as triglycerides, total cholesterol, and various types of cholesterol at different stages of supplementation. We observed that after six months of taking this supplement, participants showed a significant reduction in remnant cholesterol and maintained healthy triglyceride levels. Notably, this decrease in cholesterol did not come at the expense of raising low-density lipoprotein (LDL) levels, which is often a concern with other treatments.
These encouraging results reveal that EPA can be a beneficial addition for individuals looking to manage their cholesterol levels effectively. Importantly, our findings highlight AlmegaPL's unique position as a natural, over-the-counter option for those seeking to improve their lipid profiles.
Throughout the study, we monitored key health markers such as triglycerides, total cholesterol, and various types of cholesterol at different stages of supplementation. We observed that after six months of taking this supplement, participants showed a significant reduction in remnant cholesterol and maintained healthy triglyceride levels. Notably, this decrease in cholesterol did not come at the expense of raising low-density lipoprotein (LDL) levels, which is often a concern with other treatments.
These encouraging results reveal that EPA can be a beneficial addition for individuals looking to manage their cholesterol levels effectively. Importantly, our findings highlight AlmegaPL's unique position as a natural, over-the-counter option for those seeking to improve their lipid profiles.
Read More
User Reviews
USERS' SCORE
Good
Based on 8 Reviews
8.1
- All Reviews
- Positive Reviews
- Negative Reviews
7.5
Cholesterol reduction success
350 people found this helpful
OMEGA-3 Double Strength has a notable DHA content, perfect for those seeking to lower high cholesterol. Its unique ratio of DHA to EPA, at 2:1, makes it stand out. I noticed improvements in my skin, hair, and dry eyes. My husband, who struggled with high cholesterol, saw positive results after two and a half months of taking Omega-3 alongside lecithin. It's essential to monitor both good and bad cholesterol levels during tests. My cat loves it too, and I believe it benefits her health as well.
Read More
9
Improved cholesterol levels
211 people found this helpful
Omega 3 lowers cholesterol, reduces inflammation, and enhances skin and hair quality. Despite the fishy taste, the quality suits me fine. Although prices have surged due to currency fluctuations, investing in health is essential. We take it as a family, and the large packaging accommodates everyone.
Read More
8
Skin condition improvement
196 people found this helpful
This omega 3 is of high quality and comes in an ideal dosage. I consume two capsules during lunch and have noticed less dry skin. Overall, I've experienced significant benefits from taking omega, and I highly recommend it.
Read More
9
Family health investment
191 people found this helpful
Omega 3 effectively lowers cholesterol, reduces inflammation, and enhances skin and hair quality. The fish taste is present, but the product quality meets my needs. Although costs have risen lately, we’re committed to maintaining our health as a family with this ample supply.
Read More
9
Correct composition found
141 people found this helpful
I’ve bought this omega multiple times, as my nutritionist recommends a DHA to EPA ratio of 2:1 for our region. This product meets that need; I've previously ordered other omega supplements 2.5 times more expensive without the same quality.
Read More
Frequently Asked Questions
7.5
Cholesterol reduction success
350 people found this helpful
OMEGA-3 Double Strength has a notable DHA content, perfect for those seeking to lower high cholesterol. Its unique ratio of DHA to EPA, at 2:1, makes it stand out. I noticed improvements in my skin, hair, and dry eyes. My husband, who struggled with high cholesterol, saw positive results after two and a half months of taking Omega-3 alongside lecithin. It's essential to monitor both good and bad cholesterol levels during tests. My cat loves it too, and I believe it benefits her health as well.
7
Prevention method
169 people found this helpful
This Omega suits me perfectly. I take it for high cholesterol prevention, with just one capsule daily. Admittedly, the capsules are large and have a fish oil smell, but it's bearable. I would definitely recommend it.
8
Skin condition improvement
196 people found this helpful
This omega 3 is of high quality and comes in an ideal dosage. I consume two capsules during lunch and have noticed less dry skin. Overall, I've experienced significant benefits from taking omega, and I highly recommend it.
9
Family health investment
191 people found this helpful
Omega 3 effectively lowers cholesterol, reduces inflammation, and enhances skin and hair quality. The fish taste is present, but the product quality meets my needs. Although costs have risen lately, we’re committed to maintaining our health as a family with this ample supply.
9
Improved cholesterol levels
211 people found this helpful
Omega 3 lowers cholesterol, reduces inflammation, and enhances skin and hair quality. Despite the fishy taste, the quality suits me fine. Although prices have surged due to currency fluctuations, investing in health is essential. We take it as a family, and the large packaging accommodates everyone.
8
We explored the effects of docosahexaenoic acid (DHA) on cholesterol levels, based on a systematic review of randomized controlled trials. This research focused on the potential cardiovascular benefits of DHA, particularly its impact on high-density lipoprotein (HDL) and low-density lipoprotein (LDL) cholesterol levels.
According to the findings, DHA is effective in raising HDL cholesterol, which is considered protective against heart disease. In fact, DHA appears to have a greater impact, compared to its counterpart, eicosapentaenoic acid (EPA). Interestingly, while DHA may also elevate LDL cholesterol levels, it simultaneously increases the size of LDL particles, making them less harmful.
Furthermore, DHA was found to contribute to lowering heart rate and blood pressure, which are key factors for cardiovascular health. The research highlighted that both EPA and DHA positively influence platelet function and reduce oxidative stress and inflammation, further supporting heart health.
Although the results show that DHA has a series of beneficial effects, the information on its role in cholesterol management needed to be more definitive. More high-quality research is warranted to establish the comprehensive impact of DHA on cholesterol and other cardiovascular risk factors.
According to the findings, DHA is effective in raising HDL cholesterol, which is considered protective against heart disease. In fact, DHA appears to have a greater impact, compared to its counterpart, eicosapentaenoic acid (EPA). Interestingly, while DHA may also elevate LDL cholesterol levels, it simultaneously increases the size of LDL particles, making them less harmful.
Furthermore, DHA was found to contribute to lowering heart rate and blood pressure, which are key factors for cardiovascular health. The research highlighted that both EPA and DHA positively influence platelet function and reduce oxidative stress and inflammation, further supporting heart health.
Although the results show that DHA has a series of beneficial effects, the information on its role in cholesterol management needed to be more definitive. More high-quality research is warranted to establish the comprehensive impact of DHA on cholesterol and other cardiovascular risk factors.
8
We conducted a comprehensive study to understand how dietary intake of polyunsaturated fatty acids (PUFAs), particularly docosahexaenoic acid (DHA), relates to cholesterol levels among older adults. By analyzing data from a diverse group of 4,461 community-dwelling adults aged 65 and above, we aimed to uncover significant patterns in their dietary habits and health metrics.
Our findings revealed an interesting connection. We noticed that higher consumption of DHA, along with eicosapentaenoic acid (EPA), was associated with lower blood glucose levels. However, when we looked specifically at cholesterol levels, the results were less definitive.
The overall analysis showed that while there was an association between PUFA intake and blood glucose, the direct impact of DHA on cholesterol levels was not as clear. This suggests that while DHA may have benefits regarding overall blood sugar control, its specific effect on cholesterol needs further investigation to establish any significant benefits.
Considering these findings, it's essential to maintain a balanced diet rich in a variety of PUFAs, including omega-3 fatty acids like DHA, while also being mindful of overall health metrics such as blood pressure and cholesterol. As we continue to explore this topic, we recognize the need for more targeted studies to decipher the complex relationships between dietary fats and cardiovascular health.
Our findings revealed an interesting connection. We noticed that higher consumption of DHA, along with eicosapentaenoic acid (EPA), was associated with lower blood glucose levels. However, when we looked specifically at cholesterol levels, the results were less definitive.
The overall analysis showed that while there was an association between PUFA intake and blood glucose, the direct impact of DHA on cholesterol levels was not as clear. This suggests that while DHA may have benefits regarding overall blood sugar control, its specific effect on cholesterol needs further investigation to establish any significant benefits.
Considering these findings, it's essential to maintain a balanced diet rich in a variety of PUFAs, including omega-3 fatty acids like DHA, while also being mindful of overall health metrics such as blood pressure and cholesterol. As we continue to explore this topic, we recognize the need for more targeted studies to decipher the complex relationships between dietary fats and cardiovascular health.
8
We explored whether docosahexaenoic acid (DHA), found in algal oil, can help improve cholesterol levels and reduce the risks associated with high cholesterol. The study examined the effects of both DHA-rich algal oil and palmitoleic acid-rich sea buckthorn oil on hyperlipidemia—a condition marked by high levels of fats in the blood.
In our research, we observed that DHA oil effectively regulated lipid metabolism through specific signaling pathways, helping to lower cholesterol accumulation and reduce inflammation. When administered to mice with high-fat diets, the DHA showed promising results in improving lipid profiles and promoting better liver health.
Interestingly, we also found that combining the effects of DHA with the omega-7 fatty acids from sea buckthorn oil resulted in even more significant benefits. This combination displayed a synergistic effect, enhancing the overall efficacy compared to when each oil was used alone.
Overall, the findings suggest that DHA, especially when combined with omega-7 fatty acids, can serve as a valuable dietary supplement for managing cholesterol levels. It indicates a natural approach to tackling high cholesterol and related cardiovascular conditions.
In our research, we observed that DHA oil effectively regulated lipid metabolism through specific signaling pathways, helping to lower cholesterol accumulation and reduce inflammation. When administered to mice with high-fat diets, the DHA showed promising results in improving lipid profiles and promoting better liver health.
Interestingly, we also found that combining the effects of DHA with the omega-7 fatty acids from sea buckthorn oil resulted in even more significant benefits. This combination displayed a synergistic effect, enhancing the overall efficacy compared to when each oil was used alone.
Overall, the findings suggest that DHA, especially when combined with omega-7 fatty acids, can serve as a valuable dietary supplement for managing cholesterol levels. It indicates a natural approach to tackling high cholesterol and related cardiovascular conditions.
8
We explored how eicosapentaenoic acid (EPA) impacts cholesterol, particularly focusing on its effects in patients with high triglyceride levels. Research indicates that hypertriglyceridaemia can contribute significantly to atherosclerotic cardiovascular disease (ASCVD), even in patients who have low levels of low-density lipoprotein cholesterol (LDL-C) due to treatments like statins.
While previous studies have shown mixed results regarding the effectiveness of triglyceride-lowering medications, EPA stands out in providing favorable outcomes for certain patient groups. It's worth noting that the combination of EPA with another substance, docosahexaenoic acid (DHA), has not demonstrated the same benefits.
The key takeaway is that while the search for efficient treatments continues, isolated EPA treatment has shown promise in reducing ASCVD risk, especially for patients struggling with high triglyceride levels. This suggests that as we develop our understanding of cholesterol management, EPA could be an important piece of the puzzle for those at risk.
While previous studies have shown mixed results regarding the effectiveness of triglyceride-lowering medications, EPA stands out in providing favorable outcomes for certain patient groups. It's worth noting that the combination of EPA with another substance, docosahexaenoic acid (DHA), has not demonstrated the same benefits.
The key takeaway is that while the search for efficient treatments continues, isolated EPA treatment has shown promise in reducing ASCVD risk, especially for patients struggling with high triglyceride levels. This suggests that as we develop our understanding of cholesterol management, EPA could be an important piece of the puzzle for those at risk.
References
- Yunoki K, Matsumi H, Miyoshi T, Kubo M, Hata Y, et al. Clinical Significance of Serum Omega-3 Fatty Acids on Endothelial Function in Patients with Coronary Artery Disease Under Statin Therapy. J Cardiovasc Dev Dis. 2025;12. 10.3390/jcdd12020060
- Chang Y, Xuan Y, Zhang R, Ding X, Zeng Q, et al. Effects of Dietary Schizochytrium Algae as ω-3 PUFA Source on the Egg-Laying Quail Performance, Serum Indexes, and Egg Yolk Fatty Acids Contents. Animals (Basel). 2024;15. 10.3390/ani15010021
- Li J, Guo J, Yuen M, Yuen H, Peng Q. The comparative effects of ω-7 fatty acid-rich sea buckthorn oil and ω-3 fatty acid-rich DHA algal oil on improving high-fat diet-induced hyperlipidemia. Food Funct. 2025;16:1241. 10.1039/d4fo04961f
- Coelho-Júnior HJ, Álvarez-Bustos A, Picca A, Calvani R, Rodriguez-Mañas L, et al. Dietary Intake of Polyunsaturated Fatty Acids Is Associated with Blood Glucose and Diabetes in Community-Dwelling Older Adults. Nutrients. 2024;16. 10.3390/nu16234087
- Cabrita ARJ, Barroso C, Fontes-Sousa AP, Correia A, Teixeira L, et al. Assessing functional properties of diet protein hydrolysate and oil from fish waste on canine immune parameters, cardiac biomarkers, and fecal microbiota. Front Vet Sci. 2024;11:1449141. 10.3389/fvets.2024.1449141
- Choi JH, Park SE, Kim S. Antarctic Krill Oil Supplementation Attenuates Hypercholesterolemia, Fatty Liver, and Oxidative Stress in Diet-Induced Obese Mice. Nutrients. 2024;16. 10.3390/nu16213614
- Lamantia V, Bissonnette S, Beaudry M, Cyr Y, Rosiers CD, et al. EPA and DHA inhibit LDL-induced upregulation of human adipose tissue NLRP3 inflammasome/IL-1β pathway and its association with diabetes risk factors. Sci Rep. 2024;14:27146. 10.1038/s41598-024-73672-6
- Choi GY, Calder PC. The differential effects of eicosapentaenoic acid and docosahexaenoic acid on cardiovascular risk factors: an updated systematic review of randomized controlled trials. Front Nutr. 2024;11:1423228. 10.3389/fnut.2024.1423228
- Zhang D, Wang Z, Guo S, Sun Y, Zhou D, et al. F-Fluorodeoxyglucose positron emission tomography/computed tomography imaging reveals the protective effect of docosahexaenoic acid on glucose metabolism by reducing brain 27-hydroxycholesterol. Exp Gerontol. 2024;196:112577. 10.1016/j.exger.2024.112577
- Zhao W, Wang Y, Li J, Chen T, Yin D, et al. Efficacy and safety of omega-3-acid ethyl acetate 90 capsules in severe hypertriglyceridemia: A randomized, controlled, multicenter study. Lipids. 2024;59:145. 10.1002/lipd.12406
- Li P, Khan S, Huang Y, Lu S, Zhou P, et al. Effect of Perilla seeds inclusion on the performance, egg quality characteristics, biochemical parameters and egg yolk fatty acid composition of laying hens. Trop Anim Health Prod. 2024;56:147. 10.1007/s11250-024-03983-3
- Kobayashi Y, Fujikawa T, Haruna A, Kawano R, Ozawa M, et al. Omega-3 Fatty Acids Reduce Remnant-like Lipoprotein Cholesterol and Improve the Ankle-Brachial Index of Hemodialysis Patients with Dyslipidemia: A Pilot Study. Medicina (Kaunas). 2023;60. 10.3390/medicina60010075
- Mueller PA, Bergstrom P, Rosario S, Heard M, Pamir N. Fish Oil Supplementation Modifies the Proteome, Lipidome, and Function of High-Density Lipoprotein: Findings from a Trial in Young Healthy Adults. J Nutr. 2024;154:1130. 10.1016/j.tjnut.2024.01.007
- Aggarwal R, Bhatt DL, Steg PG, Miller M, Brinton EA, et al. Cardiovascular Outcomes With Icosapent Ethyl by Baseline Low-Density Lipoprotein Cholesterol: A Secondary Analysis of the REDUCE-IT Randomized Trial. J Am Heart Assoc. 2025;14:e038656. 10.1161/JAHA.124.038656
- Uthaiah NM, Venkataramareddy SR, Mudhol S, Sheikh AY. EPA-rich Nannochloropsis oceanica biomass regulates gut microbiota, alleviates inflammation and ameliorates liver fibrosis in rats. Food Res Int. 2025;202:115733. 10.1016/j.foodres.2025.115733
- Yoshikiyo K, Shimizu H, Nagato EG, Ishizuka S, Yamamoto T. Comparative Analysis of γ-Cyclodextrin, Perilla Oil, and Their Inclusion Complexes on Liver Injury and Dyslipidemia Associated with Elevated Gastrointestinal 12-Hydroxylated Bile Acid Levels. Molecules. 2025;30. 10.3390/molecules30020281
- Bashir B, Schofield J, Downie P, France M, Ashcroft DM, et al. Beyond LDL-C: unravelling the residual atherosclerotic cardiovascular disease risk landscape-focus on hypertriglyceridaemia. Front Cardiovasc Med. 2024;11:1389106. 10.3389/fcvm.2024.1389106
- Lin YL, Wang CL, Chiang TI. Eicosapentaenoic acid supplementation alleviates pruritus, enhances skin moisture, and mitigates depression in maintenance hemodialysis patients. Front Nephrol. 2024;4:1365809. 10.3389/fneph.2024.1365809
- Omari M, Alkhalil M. Atherosclerosis Residual Lipid Risk-Overview of Existing and Future Pharmacotherapies. J Cardiovasc Dev Dis. 2024;11. 10.3390/jcdd11040126
- Szarek M, Bhatt DL, Miller M, Brinton EA, Jacobson TA, et al. Lipoprotein(a) Blood Levels and Cardiovascular Risk Reduction With Icosapent Ethyl. J Am Coll Cardiol. 2024;83:1529. 10.1016/j.jacc.2024.02.016
- Liakos CI, Lanaras L, Bristianou M, Papadopoulos DP. Pleiotropic beneficial cardiometabolic actions of a high-purity eicosapentaenoic acid product in high cardiovascular risk individuals. Lipids. 2024;59:67. 10.1002/lipd.12391
- Ganuza E, Etomi EH, Olson M, Whisner CM. Omega-3 eicosapentaenoic polar-lipid rich extract from microalgae decreases plasma triglycerides and cholesterol in a real-world normolipidemic supplement consumer population. Front Nutr. 2024;11:1293909. 10.3389/fnut.2024.1293909
- Kaur G, Mason RP, Steg PG, Bhatt DL. Omega-3 fatty acids for cardiovascular event lowering. Eur J Prev Cardiol. 2024;31:1005. 10.1093/eurjpc/zwae003
