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SCIENTIFIC SCORE
Questionable
Based on 27 Researches
6.8
USERS' SCORE
Good
Based on 4 Reviews
8.6
Supplement Facts
Serving Size: 1 Softgel
Amount Per Serving
%DV
Calories
10
Total Fat
1 g
1%*
Polyunsaturated Fat
1 g
†
Fish Oil Concentrate
1 g (1,000 mg)
†
Docosahexaenoic Acid (DHA)
500 mg
†
Eicosapentaenoic Acid (EPA)
250 mg
†
Top Medical Research Studies
9
DHA alleviates menopausal symptoms
Neurovegetative disorders of perimenopausal women treated with docosahexaenoic acid (DHA, 625 mg).
Direct effect of DHA noted
We explored how docosahexaenoic acid (DHA), at a dosage of 625 mg, affects menopausal symptoms among perimenopausal women. Our study involved 42 participants who were assessed for various symptoms using the Kupperman Index, along with quality of life and sexual function measured through standardized scales.
After six months of DHA treatment, the women reported significant improvements in menopause symptoms, as reflected in their Kupperman Index scores. Specifically, psychological aspects of quality of life showed remarkable enhancement, while physical aspects did not exhibit notable changes.
Additionally, we observed improvements in sexual function, with increases in the Female Sexual Function Index scores and decreases in the Female Sexual Distress Scale, particularly in areas related to arousal and lubrication. Interestingly, the auditory brainstem response also indicated lower wave latencies after treatment, suggesting potential positive effects on neuronal conduction in the auditory system.
Overall, our findings suggest that DHA can effectively help mitigate some perimenopausal symptoms, thereby improving women's quality of life and aspects of sexual health.
After six months of DHA treatment, the women reported significant improvements in menopause symptoms, as reflected in their Kupperman Index scores. Specifically, psychological aspects of quality of life showed remarkable enhancement, while physical aspects did not exhibit notable changes.
Additionally, we observed improvements in sexual function, with increases in the Female Sexual Function Index scores and decreases in the Female Sexual Distress Scale, particularly in areas related to arousal and lubrication. Interestingly, the auditory brainstem response also indicated lower wave latencies after treatment, suggesting potential positive effects on neuronal conduction in the auditory system.
Overall, our findings suggest that DHA can effectively help mitigate some perimenopausal symptoms, thereby improving women's quality of life and aspects of sexual health.
Read More
8
Memory enhancement through tuna oil
Omega-3-Rich Tuna Oil Derived from By-Products of the Canned Tuna Industry Enhances Memory in an Ovariectomized Rat Model of Menopause.
Study specifically explores DHA impact
We set out to explore the effects of omega-3-rich tuna oil, particularly its docosahexaenoic acid (DHA) component, on memory in rats that underwent ovariectomy—a common model for studying menopause. Over a period of 28 days before and 21 days after the surgery, female rats were given various doses of tuna oil to assess its impact on cognitive performance.
Our findings showed that all doses of tuna oil improved memory performance. We also observed increases in beneficial substances like DHA and improvements in enzyme activities linked to brain health, such as superoxide dismutase (SOD) and glutathione peroxidase (GPx). At the same time, harmful factors such as cortisol and inflammatory cytokines decreased, which suggests that tuna oil may help to reduce stress and inflammation in the brain.
Moreover, medium and high doses of tuna oil managed to suppress monoamine oxidase, while a high dose also moderated gamma-aminotransferase, highlighting its intricate role in neurotransmitter regulation. Interestingly, no notable changes in telomere length or estrogen levels were observed, indicating that the benefits of tuna oil in this context may primarily arise from its antioxidant and anti-inflammatory effects.
Overall, our findings indicate that tuna oil could have a positive influence on memory in the context of menopause, primarily through mechanisms that alleviate oxidative stress and inflammation.
Our findings showed that all doses of tuna oil improved memory performance. We also observed increases in beneficial substances like DHA and improvements in enzyme activities linked to brain health, such as superoxide dismutase (SOD) and glutathione peroxidase (GPx). At the same time, harmful factors such as cortisol and inflammatory cytokines decreased, which suggests that tuna oil may help to reduce stress and inflammation in the brain.
Moreover, medium and high doses of tuna oil managed to suppress monoamine oxidase, while a high dose also moderated gamma-aminotransferase, highlighting its intricate role in neurotransmitter regulation. Interestingly, no notable changes in telomere length or estrogen levels were observed, indicating that the benefits of tuna oil in this context may primarily arise from its antioxidant and anti-inflammatory effects.
Overall, our findings indicate that tuna oil could have a positive influence on memory in the context of menopause, primarily through mechanisms that alleviate oxidative stress and inflammation.
Read More
9
DHA improves lipid profiles modestly
Effect of Low Dose Docosahexaenoic Acid-Rich Fish Oil on Plasma Lipids and Lipoproteins in Pre-Menopausal Women: A Dose⁻Response Randomized Placebo-Controlled Trial.
Relevant, yet indirectly related
We conducted a study to explore how docosahexaenoic acid (DHA), a type of omega-3 fatty acid found in fish oil, affects plasma lipid levels in healthy pre-menopausal women. This randomized, double-blind, placebo-controlled trial included 53 participants who were given either 0, 0.35, 0.7, or 1 gram of DHA-rich tuna oil, or a placebo for eight weeks.
Our findings showed that only the highest dose of DHA at 1 gram per day significantly reduced plasma triglycerides—by about 23%. This reduction was particularly noted in the very-low-density lipoprotein triglycerides. Additionally, although we identified a slight increase in HDL particle size with DHA supplementation, we did not observe any significant changes in LDL levels.
Overall, our research underscores that while DHA-rich supplementation can lower triglycerides and possibly improve certain lipid profiles in pre-menopausal women, the effects don’t specifically address menopause symptoms.
Our findings showed that only the highest dose of DHA at 1 gram per day significantly reduced plasma triglycerides—by about 23%. This reduction was particularly noted in the very-low-density lipoprotein triglycerides. Additionally, although we identified a slight increase in HDL particle size with DHA supplementation, we did not observe any significant changes in LDL levels.
Overall, our research underscores that while DHA-rich supplementation can lower triglycerides and possibly improve certain lipid profiles in pre-menopausal women, the effects don’t specifically address menopause symptoms.
Read More
Most Useful Reviews
8.8
Skin rejuvenation
Best! I adore this fish oil! It has undeniably rejuvenated my skin, making it more elastic and smoother. Despite being 56 and on HRT since menopause began at 48, my skin was fading. This "fish" is a lifesaver for my skin, hair, and nails. My sister's thin hair also became stronger. The high docosahexaenoic acid content is beneficial for cardiovascular health and has reduced my migraines. I highly recommend it but remember to follow the dosage and consult your doctor first.
Read More
8
Supports menopause symptoms
Omega 3-PUFA contains vital docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA), which the body cannot synthesise. To get sufficient EPA and DHA, one must eat plenty of fish. PUFAs effectively address various female issues, particularly during menopause, reducing risks of premature birth, alleviating menstrual pain, and possibly protecting against breast cancer.
Read More
8.8
Menopause guidance
I consistently repurchase this fish oil and take one capsule at a time, on my gynaecologist's advice during menopause. Although the capsule is large, it's easy to swallow!
Read More
Medical Researches
SCIENTIFIC SCORE
Questionable
Based on 27 Researches
6.8
9
DHA linked to breast density changes
Omega-3 Fatty Acids Responsive Proteins and Reduction in Breast Density in Obese Postmenopausal Women.
Significant findings on DHA's impact
We explored the relationship between docosahexaenoic acid (DHA), a type of omega-3 fatty acid, and breast density among postmenopausal women, particularly focusing on those who are obese. Our study aimed to understand how DHA might differentially affect breast density in obese versus nonobese women, using a method called iTRAQ to analyze plasma samples over two years.
During the study, we identified 173 proteins in the plasma samples. Some of these proteins showed different levels of expression based on whether women were obese or lean. Notably, proteins like the vitamin D binding protein and fibronectin were altered, which suggests a connection between DHA intake and reduced inflammation in obese women.
Our findings indicated that there is an inverse relationship between DHA levels and breast density specifically in postmenopausal obese women. This suggests that greater DHA intake could potentially reduce breast density and may decrease breast cancer risk in this demographic. However, it’s important to note that the effect was not observed in nonobese women.
Overall, this research highlights DHA's role in impacting breast health during menopause, particularly for those with obesity. It opens up further discussions on how dietary changes could play a role in cancer prevention strategies for women going through menopause.
During the study, we identified 173 proteins in the plasma samples. Some of these proteins showed different levels of expression based on whether women were obese or lean. Notably, proteins like the vitamin D binding protein and fibronectin were altered, which suggests a connection between DHA intake and reduced inflammation in obese women.
Our findings indicated that there is an inverse relationship between DHA levels and breast density specifically in postmenopausal obese women. This suggests that greater DHA intake could potentially reduce breast density and may decrease breast cancer risk in this demographic. However, it’s important to note that the effect was not observed in nonobese women.
Overall, this research highlights DHA's role in impacting breast health during menopause, particularly for those with obesity. It opens up further discussions on how dietary changes could play a role in cancer prevention strategies for women going through menopause.
Read More
9
DHA improves lipid profiles modestly
Effect of Low Dose Docosahexaenoic Acid-Rich Fish Oil on Plasma Lipids and Lipoproteins in Pre-Menopausal Women: A Dose⁻Response Randomized Placebo-Controlled Trial.
Relevant, yet indirectly related
We conducted a study to explore how docosahexaenoic acid (DHA), a type of omega-3 fatty acid found in fish oil, affects plasma lipid levels in healthy pre-menopausal women. This randomized, double-blind, placebo-controlled trial included 53 participants who were given either 0, 0.35, 0.7, or 1 gram of DHA-rich tuna oil, or a placebo for eight weeks.
Our findings showed that only the highest dose of DHA at 1 gram per day significantly reduced plasma triglycerides—by about 23%. This reduction was particularly noted in the very-low-density lipoprotein triglycerides. Additionally, although we identified a slight increase in HDL particle size with DHA supplementation, we did not observe any significant changes in LDL levels.
Overall, our research underscores that while DHA-rich supplementation can lower triglycerides and possibly improve certain lipid profiles in pre-menopausal women, the effects don’t specifically address menopause symptoms.
Our findings showed that only the highest dose of DHA at 1 gram per day significantly reduced plasma triglycerides—by about 23%. This reduction was particularly noted in the very-low-density lipoprotein triglycerides. Additionally, although we identified a slight increase in HDL particle size with DHA supplementation, we did not observe any significant changes in LDL levels.
Overall, our research underscores that while DHA-rich supplementation can lower triglycerides and possibly improve certain lipid profiles in pre-menopausal women, the effects don’t specifically address menopause symptoms.
Read More
9
DHA alleviates menopausal symptoms
Neurovegetative disorders of perimenopausal women treated with docosahexaenoic acid (DHA, 625 mg).
Direct effect of DHA noted
We explored how docosahexaenoic acid (DHA), at a dosage of 625 mg, affects menopausal symptoms among perimenopausal women. Our study involved 42 participants who were assessed for various symptoms using the Kupperman Index, along with quality of life and sexual function measured through standardized scales.
After six months of DHA treatment, the women reported significant improvements in menopause symptoms, as reflected in their Kupperman Index scores. Specifically, psychological aspects of quality of life showed remarkable enhancement, while physical aspects did not exhibit notable changes.
Additionally, we observed improvements in sexual function, with increases in the Female Sexual Function Index scores and decreases in the Female Sexual Distress Scale, particularly in areas related to arousal and lubrication. Interestingly, the auditory brainstem response also indicated lower wave latencies after treatment, suggesting potential positive effects on neuronal conduction in the auditory system.
Overall, our findings suggest that DHA can effectively help mitigate some perimenopausal symptoms, thereby improving women's quality of life and aspects of sexual health.
After six months of DHA treatment, the women reported significant improvements in menopause symptoms, as reflected in their Kupperman Index scores. Specifically, psychological aspects of quality of life showed remarkable enhancement, while physical aspects did not exhibit notable changes.
Additionally, we observed improvements in sexual function, with increases in the Female Sexual Function Index scores and decreases in the Female Sexual Distress Scale, particularly in areas related to arousal and lubrication. Interestingly, the auditory brainstem response also indicated lower wave latencies after treatment, suggesting potential positive effects on neuronal conduction in the auditory system.
Overall, our findings suggest that DHA can effectively help mitigate some perimenopausal symptoms, thereby improving women's quality of life and aspects of sexual health.
Read More
9
Eicosapentaenoic acid and estradiol
Association between polyunsaturated fatty acid intake and estradiol levels among U.S. women.
Significant dietary influence noted
We explored the relationship between eicosapentaenoic acid (EPA) intake and estradiol levels in women, specifically focusing on its effects during menopause. The study utilized data from the National Health and Nutrition Examination Survey, which included dietary interviews and serum estradiol level measurements.
Our findings highlighted that higher intakes of EPA were associated with increased estradiol levels in both menopausal and non-menopausal women. Importantly, we noted that EPA intake above a certain threshold was linked to these hormonal changes.
This research suggests that incorporating more EPA into the diet could play a role in regulating estradiol levels, which is particularly beneficial for women's reproductive health during and after menopause. Understanding these connections helps emphasize the importance of nutrition in hormone regulation.
Our findings highlighted that higher intakes of EPA were associated with increased estradiol levels in both menopausal and non-menopausal women. Importantly, we noted that EPA intake above a certain threshold was linked to these hormonal changes.
This research suggests that incorporating more EPA into the diet could play a role in regulating estradiol levels, which is particularly beneficial for women's reproductive health during and after menopause. Understanding these connections helps emphasize the importance of nutrition in hormone regulation.
Read More
8
DHA linked to delayed menopause
Genetically Determined Plasma Docosahexaenoic Acid Showed a Causal Association with Female Reproductive Longevity-Related Phenotype: A Mendelian Randomization Study.
Research shows DHA's impact
We explored the impact of docosahexaenoic acid (DHA), a type of omega-3 fatty acid, on the timing of menopause. Utilizing a two-sample Mendelian randomization approach, we sought to determine whether DHA could influence female reproductive longevity by examining age at menarche and age at natural menopause.
Our study analyzed data from a large number of participants, including over 200,000 European women and nearly 44,000 East Asian women, to gauge the effects of plasma levels of various polyunsaturated fatty acids on reproductive milestones.
The findings revealed that higher levels of DHA in the blood are linked to a delayed onset of natural menopause, while they did not seem to influence the age of first menstruation. This suggests that DHA could be an important factor for women looking to extend their reproductive lifespan, providing a potential target for future health interventions.
Our study analyzed data from a large number of participants, including over 200,000 European women and nearly 44,000 East Asian women, to gauge the effects of plasma levels of various polyunsaturated fatty acids on reproductive milestones.
The findings revealed that higher levels of DHA in the blood are linked to a delayed onset of natural menopause, while they did not seem to influence the age of first menstruation. This suggests that DHA could be an important factor for women looking to extend their reproductive lifespan, providing a potential target for future health interventions.
Read More
User Reviews
USERS' SCORE
Good
Based on 4 Reviews
8.6
8.8
Skin rejuvenation
Best! I adore this fish oil! It has undeniably rejuvenated my skin, making it more elastic and smoother. Despite being 56 and on HRT since menopause began at 48, my skin was fading. This "fish" is a lifesaver for my skin, hair, and nails. My sister's thin hair also became stronger. The high docosahexaenoic acid content is beneficial for cardiovascular health and has reduced my migraines. I highly recommend it but remember to follow the dosage and consult your doctor first.
Read More
8.8
Menopause guidance
I consistently repurchase this fish oil and take one capsule at a time, on my gynaecologist's advice during menopause. Although the capsule is large, it's easy to swallow!
8.8
Supports menopause health
A very good product! I've used it for years, initially for fertility issues, and now for menopause.
8
Supports menopause symptoms
Omega 3-PUFA contains vital docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA), which the body cannot synthesise. To get sufficient EPA and DHA, one must eat plenty of fish. PUFAs effectively address various female issues, particularly during menopause, reducing risks of premature birth, alleviating menstrual pain, and possibly protecting against breast cancer.
Read More
