Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 20 Researches
7.2
USERS' SCORE
Good
Based on 4 Reviews
8.2
Supplement Facts
Serving Size: 1 Softgel
Amount Per Serving
%DV
Calories
10
Total Fat
1 g
1%*
Polyunsaturated Fat
1 g
†
Fish Oil Concentrate
1 g (1,000 mg)
†
Docosahexaenoic Acid (DHA)
500 mg
†
Eicosapentaenoic Acid (EPA)
250 mg
†
Top Medical Research Studies
9
We explored how docosahexaenoic acid (DHA), at a dosage of 625 mg, affects menopausal symptoms among perimenopausal women. Our study involved 42 participants who were assessed for various symptoms using the Kupperman Index, along with quality of life and sexual function measured through standardized scales.
After six months of DHA treatment, the women reported significant improvements in menopause symptoms, as reflected in their Kupperman Index scores. Specifically, psychological aspects of quality of life showed remarkable enhancement, while physical aspects did not exhibit notable changes.
Additionally, we observed improvements in sexual function, with increases in the Female Sexual Function Index scores and decreases in the Female Sexual Distress Scale, particularly in areas related to arousal and lubrication. Interestingly, the auditory brainstem response also indicated lower wave latencies after treatment, suggesting potential positive effects on neuronal conduction in the auditory system.
Overall, our findings suggest that DHA can effectively help mitigate some perimenopausal symptoms, thereby improving women's quality of life and aspects of sexual health.
After six months of DHA treatment, the women reported significant improvements in menopause symptoms, as reflected in their Kupperman Index scores. Specifically, psychological aspects of quality of life showed remarkable enhancement, while physical aspects did not exhibit notable changes.
Additionally, we observed improvements in sexual function, with increases in the Female Sexual Function Index scores and decreases in the Female Sexual Distress Scale, particularly in areas related to arousal and lubrication. Interestingly, the auditory brainstem response also indicated lower wave latencies after treatment, suggesting potential positive effects on neuronal conduction in the auditory system.
Overall, our findings suggest that DHA can effectively help mitigate some perimenopausal symptoms, thereby improving women's quality of life and aspects of sexual health.
Read More
8
We set out to explore the effects of omega-3-rich tuna oil, particularly its docosahexaenoic acid (DHA) component, on memory in rats that underwent ovariectomy—a common model for studying menopause. Over a period of 28 days before and 21 days after the surgery, female rats were given various doses of tuna oil to assess its impact on cognitive performance.
Our findings showed that all doses of tuna oil improved memory performance. We also observed increases in beneficial substances like DHA and improvements in enzyme activities linked to brain health, such as superoxide dismutase (SOD) and glutathione peroxidase (GPx). At the same time, harmful factors such as cortisol and inflammatory cytokines decreased, which suggests that tuna oil may help to reduce stress and inflammation in the brain.
Moreover, medium and high doses of tuna oil managed to suppress monoamine oxidase, while a high dose also moderated gamma-aminotransferase, highlighting its intricate role in neurotransmitter regulation. Interestingly, no notable changes in telomere length or estrogen levels were observed, indicating that the benefits of tuna oil in this context may primarily arise from its antioxidant and anti-inflammatory effects.
Overall, our findings indicate that tuna oil could have a positive influence on memory in the context of menopause, primarily through mechanisms that alleviate oxidative stress and inflammation.
Our findings showed that all doses of tuna oil improved memory performance. We also observed increases in beneficial substances like DHA and improvements in enzyme activities linked to brain health, such as superoxide dismutase (SOD) and glutathione peroxidase (GPx). At the same time, harmful factors such as cortisol and inflammatory cytokines decreased, which suggests that tuna oil may help to reduce stress and inflammation in the brain.
Moreover, medium and high doses of tuna oil managed to suppress monoamine oxidase, while a high dose also moderated gamma-aminotransferase, highlighting its intricate role in neurotransmitter regulation. Interestingly, no notable changes in telomere length or estrogen levels were observed, indicating that the benefits of tuna oil in this context may primarily arise from its antioxidant and anti-inflammatory effects.
Overall, our findings indicate that tuna oil could have a positive influence on memory in the context of menopause, primarily through mechanisms that alleviate oxidative stress and inflammation.
Read More
9
We conducted a study to explore how docosahexaenoic acid (DHA), a type of omega-3 fatty acid found in fish oil, affects plasma lipid levels in healthy pre-menopausal women. This randomized, double-blind, placebo-controlled trial included 53 participants who were given either 0, 0.35, 0.7, or 1 gram of DHA-rich tuna oil, or a placebo for eight weeks.
Our findings showed that only the highest dose of DHA at 1 gram per day significantly reduced plasma triglycerides—by about 23%. This reduction was particularly noted in the very-low-density lipoprotein triglycerides. Additionally, although we identified a slight increase in HDL particle size with DHA supplementation, we did not observe any significant changes in LDL levels.
Overall, our research underscores that while DHA-rich supplementation can lower triglycerides and possibly improve certain lipid profiles in pre-menopausal women, the effects don’t specifically address menopause symptoms.
Our findings showed that only the highest dose of DHA at 1 gram per day significantly reduced plasma triglycerides—by about 23%. This reduction was particularly noted in the very-low-density lipoprotein triglycerides. Additionally, although we identified a slight increase in HDL particle size with DHA supplementation, we did not observe any significant changes in LDL levels.
Overall, our research underscores that while DHA-rich supplementation can lower triglycerides and possibly improve certain lipid profiles in pre-menopausal women, the effects don’t specifically address menopause symptoms.
Read More
Most Useful Reviews
7.5
Skin rejuvenation
107 people found this helpful
Best! I adore this fish oil! It has undeniably rejuvenated my skin, making it more elastic and smoother. Despite being 56 and on HRT since menopause began at 48, my skin was fading. This "fish" is a lifesaver for my skin, hair, and nails. My sister's thin hair also became stronger. The high docosahexaenoic acid content is beneficial for cardiovascular health and has reduced my migraines. I highly recommend it but remember to follow the dosage and consult your doctor first.
Read More
6
Supports menopause symptoms
2 people found this helpful
Omega 3-PUFA contains vital docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA), which the body cannot synthesise. To get sufficient EPA and DHA, one must eat plenty of fish. PUFAs effectively address various female issues, particularly during menopause, reducing risks of premature birth, alleviating menstrual pain, and possibly protecting against breast cancer.
Read More
7.5
Menopause guidance
I consistently repurchase this fish oil and take one capsule at a time, on my gynaecologist's advice during menopause. Although the capsule is large, it's easy to swallow!
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 20 Researches
7.2
- All Researches
9
We explored the relationship between docosahexaenoic acid (DHA), a type of omega-3 fatty acid, and breast density among postmenopausal women, particularly focusing on those who are obese. Our study aimed to understand how DHA might differentially affect breast density in obese versus nonobese women, using a method called iTRAQ to analyze plasma samples over two years.
During the study, we identified 173 proteins in the plasma samples. Some of these proteins showed different levels of expression based on whether women were obese or lean. Notably, proteins like the vitamin D binding protein and fibronectin were altered, which suggests a connection between DHA intake and reduced inflammation in obese women.
Our findings indicated that there is an inverse relationship between DHA levels and breast density specifically in postmenopausal obese women. This suggests that greater DHA intake could potentially reduce breast density and may decrease breast cancer risk in this demographic. However, it’s important to note that the effect was not observed in nonobese women.
Overall, this research highlights DHA's role in impacting breast health during menopause, particularly for those with obesity. It opens up further discussions on how dietary changes could play a role in cancer prevention strategies for women going through menopause.
During the study, we identified 173 proteins in the plasma samples. Some of these proteins showed different levels of expression based on whether women were obese or lean. Notably, proteins like the vitamin D binding protein and fibronectin were altered, which suggests a connection between DHA intake and reduced inflammation in obese women.
Our findings indicated that there is an inverse relationship between DHA levels and breast density specifically in postmenopausal obese women. This suggests that greater DHA intake could potentially reduce breast density and may decrease breast cancer risk in this demographic. However, it’s important to note that the effect was not observed in nonobese women.
Overall, this research highlights DHA's role in impacting breast health during menopause, particularly for those with obesity. It opens up further discussions on how dietary changes could play a role in cancer prevention strategies for women going through menopause.
Read More
9
We conducted a study to explore how docosahexaenoic acid (DHA), a type of omega-3 fatty acid found in fish oil, affects plasma lipid levels in healthy pre-menopausal women. This randomized, double-blind, placebo-controlled trial included 53 participants who were given either 0, 0.35, 0.7, or 1 gram of DHA-rich tuna oil, or a placebo for eight weeks.
Our findings showed that only the highest dose of DHA at 1 gram per day significantly reduced plasma triglycerides—by about 23%. This reduction was particularly noted in the very-low-density lipoprotein triglycerides. Additionally, although we identified a slight increase in HDL particle size with DHA supplementation, we did not observe any significant changes in LDL levels.
Overall, our research underscores that while DHA-rich supplementation can lower triglycerides and possibly improve certain lipid profiles in pre-menopausal women, the effects don’t specifically address menopause symptoms.
Our findings showed that only the highest dose of DHA at 1 gram per day significantly reduced plasma triglycerides—by about 23%. This reduction was particularly noted in the very-low-density lipoprotein triglycerides. Additionally, although we identified a slight increase in HDL particle size with DHA supplementation, we did not observe any significant changes in LDL levels.
Overall, our research underscores that while DHA-rich supplementation can lower triglycerides and possibly improve certain lipid profiles in pre-menopausal women, the effects don’t specifically address menopause symptoms.
Read More
9
We explored how docosahexaenoic acid (DHA), at a dosage of 625 mg, affects menopausal symptoms among perimenopausal women. Our study involved 42 participants who were assessed for various symptoms using the Kupperman Index, along with quality of life and sexual function measured through standardized scales.
After six months of DHA treatment, the women reported significant improvements in menopause symptoms, as reflected in their Kupperman Index scores. Specifically, psychological aspects of quality of life showed remarkable enhancement, while physical aspects did not exhibit notable changes.
Additionally, we observed improvements in sexual function, with increases in the Female Sexual Function Index scores and decreases in the Female Sexual Distress Scale, particularly in areas related to arousal and lubrication. Interestingly, the auditory brainstem response also indicated lower wave latencies after treatment, suggesting potential positive effects on neuronal conduction in the auditory system.
Overall, our findings suggest that DHA can effectively help mitigate some perimenopausal symptoms, thereby improving women's quality of life and aspects of sexual health.
After six months of DHA treatment, the women reported significant improvements in menopause symptoms, as reflected in their Kupperman Index scores. Specifically, psychological aspects of quality of life showed remarkable enhancement, while physical aspects did not exhibit notable changes.
Additionally, we observed improvements in sexual function, with increases in the Female Sexual Function Index scores and decreases in the Female Sexual Distress Scale, particularly in areas related to arousal and lubrication. Interestingly, the auditory brainstem response also indicated lower wave latencies after treatment, suggesting potential positive effects on neuronal conduction in the auditory system.
Overall, our findings suggest that DHA can effectively help mitigate some perimenopausal symptoms, thereby improving women's quality of life and aspects of sexual health.
Read More
9
We explored the relationship between eicosapentaenoic acid (EPA) intake and estradiol levels in women, specifically focusing on its effects during menopause. The study utilized data from the National Health and Nutrition Examination Survey, which included dietary interviews and serum estradiol level measurements.
Our findings highlighted that higher intakes of EPA were associated with increased estradiol levels in both menopausal and non-menopausal women. Importantly, we noted that EPA intake above a certain threshold was linked to these hormonal changes.
This research suggests that incorporating more EPA into the diet could play a role in regulating estradiol levels, which is particularly beneficial for women's reproductive health during and after menopause. Understanding these connections helps emphasize the importance of nutrition in hormone regulation.
Our findings highlighted that higher intakes of EPA were associated with increased estradiol levels in both menopausal and non-menopausal women. Importantly, we noted that EPA intake above a certain threshold was linked to these hormonal changes.
This research suggests that incorporating more EPA into the diet could play a role in regulating estradiol levels, which is particularly beneficial for women's reproductive health during and after menopause. Understanding these connections helps emphasize the importance of nutrition in hormone regulation.
Read More
8
We explored the impact of docosahexaenoic acid (DHA), a type of omega-3 fatty acid, on the timing of menopause. Utilizing a two-sample Mendelian randomization approach, we sought to determine whether DHA could influence female reproductive longevity by examining age at menarche and age at natural menopause.
Our study analyzed data from a large number of participants, including over 200,000 European women and nearly 44,000 East Asian women, to gauge the effects of plasma levels of various polyunsaturated fatty acids on reproductive milestones.
The findings revealed that higher levels of DHA in the blood are linked to a delayed onset of natural menopause, while they did not seem to influence the age of first menstruation. This suggests that DHA could be an important factor for women looking to extend their reproductive lifespan, providing a potential target for future health interventions.
Our study analyzed data from a large number of participants, including over 200,000 European women and nearly 44,000 East Asian women, to gauge the effects of plasma levels of various polyunsaturated fatty acids on reproductive milestones.
The findings revealed that higher levels of DHA in the blood are linked to a delayed onset of natural menopause, while they did not seem to influence the age of first menstruation. This suggests that DHA could be an important factor for women looking to extend their reproductive lifespan, providing a potential target for future health interventions.
Read More
User Reviews
USERS' SCORE
Good
Based on 4 Reviews
8.2
- All Reviews
- Positive Reviews
- Negative Reviews
7.5
Skin rejuvenation
107 people found this helpful
Best! I adore this fish oil! It has undeniably rejuvenated my skin, making it more elastic and smoother. Despite being 56 and on HRT since menopause began at 48, my skin was fading. This "fish" is a lifesaver for my skin, hair, and nails. My sister's thin hair also became stronger. The high docosahexaenoic acid content is beneficial for cardiovascular health and has reduced my migraines. I highly recommend it but remember to follow the dosage and consult your doctor first.
Read More
6
Supports menopause symptoms
2 people found this helpful
Omega 3-PUFA contains vital docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA), which the body cannot synthesise. To get sufficient EPA and DHA, one must eat plenty of fish. PUFAs effectively address various female issues, particularly during menopause, reducing risks of premature birth, alleviating menstrual pain, and possibly protecting against breast cancer.
Read More
7.5
Menopause guidance
I consistently repurchase this fish oil and take one capsule at a time, on my gynaecologist's advice during menopause. Although the capsule is large, it's easy to swallow!
Read More
7.5
Supports menopause health
A very good product! I've used it for years, initially for fertility issues, and now for menopause.
Read More
Frequently Asked Questions
7.5
Skin rejuvenation
107 people found this helpful
Best! I adore this fish oil! It has undeniably rejuvenated my skin, making it more elastic and smoother. Despite being 56 and on HRT since menopause began at 48, my skin was fading. This "fish" is a lifesaver for my skin, hair, and nails. My sister's thin hair also became stronger. The high docosahexaenoic acid content is beneficial for cardiovascular health and has reduced my migraines. I highly recommend it but remember to follow the dosage and consult your doctor first.
7.5
Supports menopause health
A very good product! I've used it for years, initially for fertility issues, and now for menopause.
6
Supports menopause symptoms
2 people found this helpful
Omega 3-PUFA contains vital docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA), which the body cannot synthesise. To get sufficient EPA and DHA, one must eat plenty of fish. PUFAs effectively address various female issues, particularly during menopause, reducing risks of premature birth, alleviating menstrual pain, and possibly protecting against breast cancer.
7.5
Menopause guidance
I consistently repurchase this fish oil and take one capsule at a time, on my gynaecologist's advice during menopause. Although the capsule is large, it's easy to swallow!
8
We explored the impact of docosahexaenoic acid (DHA), a type of omega-3 fatty acid, on the timing of menopause. Utilizing a two-sample Mendelian randomization approach, we sought to determine whether DHA could influence female reproductive longevity by examining age at menarche and age at natural menopause.
Our study analyzed data from a large number of participants, including over 200,000 European women and nearly 44,000 East Asian women, to gauge the effects of plasma levels of various polyunsaturated fatty acids on reproductive milestones.
The findings revealed that higher levels of DHA in the blood are linked to a delayed onset of natural menopause, while they did not seem to influence the age of first menstruation. This suggests that DHA could be an important factor for women looking to extend their reproductive lifespan, providing a potential target for future health interventions.
Our study analyzed data from a large number of participants, including over 200,000 European women and nearly 44,000 East Asian women, to gauge the effects of plasma levels of various polyunsaturated fatty acids on reproductive milestones.
The findings revealed that higher levels of DHA in the blood are linked to a delayed onset of natural menopause, while they did not seem to influence the age of first menstruation. This suggests that DHA could be an important factor for women looking to extend their reproductive lifespan, providing a potential target for future health interventions.
8
We set out to explore the effects of omega-3-rich tuna oil, particularly its docosahexaenoic acid (DHA) component, on memory in rats that underwent ovariectomy—a common model for studying menopause. Over a period of 28 days before and 21 days after the surgery, female rats were given various doses of tuna oil to assess its impact on cognitive performance.
Our findings showed that all doses of tuna oil improved memory performance. We also observed increases in beneficial substances like DHA and improvements in enzyme activities linked to brain health, such as superoxide dismutase (SOD) and glutathione peroxidase (GPx). At the same time, harmful factors such as cortisol and inflammatory cytokines decreased, which suggests that tuna oil may help to reduce stress and inflammation in the brain.
Moreover, medium and high doses of tuna oil managed to suppress monoamine oxidase, while a high dose also moderated gamma-aminotransferase, highlighting its intricate role in neurotransmitter regulation. Interestingly, no notable changes in telomere length or estrogen levels were observed, indicating that the benefits of tuna oil in this context may primarily arise from its antioxidant and anti-inflammatory effects.
Overall, our findings indicate that tuna oil could have a positive influence on memory in the context of menopause, primarily through mechanisms that alleviate oxidative stress and inflammation.
Our findings showed that all doses of tuna oil improved memory performance. We also observed increases in beneficial substances like DHA and improvements in enzyme activities linked to brain health, such as superoxide dismutase (SOD) and glutathione peroxidase (GPx). At the same time, harmful factors such as cortisol and inflammatory cytokines decreased, which suggests that tuna oil may help to reduce stress and inflammation in the brain.
Moreover, medium and high doses of tuna oil managed to suppress monoamine oxidase, while a high dose also moderated gamma-aminotransferase, highlighting its intricate role in neurotransmitter regulation. Interestingly, no notable changes in telomere length or estrogen levels were observed, indicating that the benefits of tuna oil in this context may primarily arise from its antioxidant and anti-inflammatory effects.
Overall, our findings indicate that tuna oil could have a positive influence on memory in the context of menopause, primarily through mechanisms that alleviate oxidative stress and inflammation.
9
We explored how docosahexaenoic acid (DHA), at a dosage of 625 mg, affects menopausal symptoms among perimenopausal women. Our study involved 42 participants who were assessed for various symptoms using the Kupperman Index, along with quality of life and sexual function measured through standardized scales.
After six months of DHA treatment, the women reported significant improvements in menopause symptoms, as reflected in their Kupperman Index scores. Specifically, psychological aspects of quality of life showed remarkable enhancement, while physical aspects did not exhibit notable changes.
Additionally, we observed improvements in sexual function, with increases in the Female Sexual Function Index scores and decreases in the Female Sexual Distress Scale, particularly in areas related to arousal and lubrication. Interestingly, the auditory brainstem response also indicated lower wave latencies after treatment, suggesting potential positive effects on neuronal conduction in the auditory system.
Overall, our findings suggest that DHA can effectively help mitigate some perimenopausal symptoms, thereby improving women's quality of life and aspects of sexual health.
After six months of DHA treatment, the women reported significant improvements in menopause symptoms, as reflected in their Kupperman Index scores. Specifically, psychological aspects of quality of life showed remarkable enhancement, while physical aspects did not exhibit notable changes.
Additionally, we observed improvements in sexual function, with increases in the Female Sexual Function Index scores and decreases in the Female Sexual Distress Scale, particularly in areas related to arousal and lubrication. Interestingly, the auditory brainstem response also indicated lower wave latencies after treatment, suggesting potential positive effects on neuronal conduction in the auditory system.
Overall, our findings suggest that DHA can effectively help mitigate some perimenopausal symptoms, thereby improving women's quality of life and aspects of sexual health.
8
We aimed to understand how docosahexaenoic acid (DHA), found in specially enriched milk, affects postmenopausal women, particularly regarding heart health and bone density. The study involved 117 healthy postmenopausal women, divided into two groups.
One group consumed 0.5 liters of low-lactose skimmed milk enhanced with DHA, eicosapentaenoic acid (EPA), oleic acid, vitamins, and calcium each day. The other group drank regular semiskimmed milk, enriched with vitamins A and D, for the same duration.
After 12 months, our findings showed promising improvements in the group that consumed the enriched milk. This group saw notable decreases in various cardiovascular risk markers, such as total cholesterol and low-density lipoprotein (LDL) levels. However, there were no significant changes observed in bone turnover markers or other relevant bone health indicators.
Overall, while we noted beneficial effects on heart health, we did not find substantial evidence that DHA, on its own or in combination with other nutrients, significantly impacted bone metabolism in postmenopausal women. Nonetheless, regularly drinking this enriched dairy product may support cardiovascular health during menopause.
One group consumed 0.5 liters of low-lactose skimmed milk enhanced with DHA, eicosapentaenoic acid (EPA), oleic acid, vitamins, and calcium each day. The other group drank regular semiskimmed milk, enriched with vitamins A and D, for the same duration.
After 12 months, our findings showed promising improvements in the group that consumed the enriched milk. This group saw notable decreases in various cardiovascular risk markers, such as total cholesterol and low-density lipoprotein (LDL) levels. However, there were no significant changes observed in bone turnover markers or other relevant bone health indicators.
Overall, while we noted beneficial effects on heart health, we did not find substantial evidence that DHA, on its own or in combination with other nutrients, significantly impacted bone metabolism in postmenopausal women. Nonetheless, regularly drinking this enriched dairy product may support cardiovascular health during menopause.
8
We set out to explore how the quality of dietary fats, particularly docosahexaenoic acid (DHA), influences menopausal symptoms in women. In a thorough study involving 393 postmenopausal women in Iran, we assessed their dietary intakes alongside their reported menopausal symptoms using well-established questionnaires.
Our findings highlighted a noteworthy pattern: women who consumed higher amounts of n-3 polyunsaturated fatty acids (PUFA), which includes DHA, reported fewer symptoms related to menopause. Specifically, those in the highest intakes of DHA experienced reduced occurrences of urogenital symptoms. On the flip side, women with high intakes of monounsaturated fatty acids (MUFA) faced more somatic symptoms.
This suggests that a diet low in MUFA but rich in n-3 PUFA—and a balanced n-3:n-6 PUFA ratio—could be beneficial for easing the discomfort often faced during menopause. While DHA is just one piece of the puzzle, its role in a healthier dietary fat profile may offer a supportive approach to managing menopausal symptoms.
Our findings highlighted a noteworthy pattern: women who consumed higher amounts of n-3 polyunsaturated fatty acids (PUFA), which includes DHA, reported fewer symptoms related to menopause. Specifically, those in the highest intakes of DHA experienced reduced occurrences of urogenital symptoms. On the flip side, women with high intakes of monounsaturated fatty acids (MUFA) faced more somatic symptoms.
This suggests that a diet low in MUFA but rich in n-3 PUFA—and a balanced n-3:n-6 PUFA ratio—could be beneficial for easing the discomfort often faced during menopause. While DHA is just one piece of the puzzle, its role in a healthier dietary fat profile may offer a supportive approach to managing menopausal symptoms.
References
- Gao H, Ying Y, Sun J, Huang Y, Li X, et al. Genetically Determined Plasma Docosahexaenoic Acid Showed a Causal Association with Female Reproductive Longevity-Related Phenotype: A Mendelian Randomization Study. Nutrients. 2024;16. doi:10.3390/nu16234103
- Wattanathorn J, Thukham-Mee W. Omega-3-Rich Tuna Oil Derived from By-Products of the Canned Tuna Industry Enhances Memory in an Ovariectomized Rat Model of Menopause. Antioxidants (Basel). 2024;13. doi:10.3390/antiox13060637
- Félix-Soriano E, Martínez-Gayo A, Cobo MJ, Pérez-Chávez A, Ibáñez-Santos J, et al. Effects of DHA-Rich n-3 Fatty Acid Supplementation and/or Resistance Training on Body Composition and Cardiometabolic Biomarkers in Overweight and Obese Post-Menopausal Women. Nutrients. 2021;13. doi:10.3390/nu13072465
- Konuri A, Bhat KMR, Rai KS, Gourishetti K, Phaneendra M YS. Supplementation of fenugreek with choline-docosahexaenoic acid attenuates menopause induced memory loss, BDNF and dendritic arborization in ovariectomized rats. Anat Sci Int. 2021;96:197. doi:10.1007/s12565-020-00574-8
- Sun YW, Xu H, Benitez G, Chen KM, Stanley A, et al. Omega-3 Fatty Acids Responsive Proteins and Reduction in Breast Density in Obese Postmenopausal Women. J Proteome Res. 2019;18:3461. doi:10.1021/acs.jproteome.9b00356
- Putti JS, Engers VK, Heemann FM, Salomon TB, Benfato MS, et al. Effects of lipoic acid and ω-3 long-chain polyunsaturated fatty acids on the kidney in the ovariectomized rat model of menopause. Nutrition. 2019;66:173. doi:10.1016/j.nut.2019.05.003
- Marinho PM, Salomon TB, Andrade AS, Behling CS, Putti JS, et al. The effect of n-3 long-chain polyunsaturated fatty acids and lipoic acid on the heart in the ovariectomized rat model of menopause. Free Radic Res. 2019;53:669. doi:10.1080/10715762.2019.1620938
- Abshirini M, Siassi F, Koohdani F, Qorbani M, Khosravi S, et al. Higher intake of dietary n-3 PUFA and lower MUFA are associated with fewer menopausal symptoms. Climacteric. 2019;22:195. doi:10.1080/13697137.2018.1547700
- Sparkes C, Gibson R, Sinclair A, Else PL, Meyer BJ. Effect of Low Dose Docosahexaenoic Acid-Rich Fish Oil on Plasma Lipids and Lipoproteins in Pre-Menopausal Women: A Dose⁻Response Randomized Placebo-Controlled Trial. Nutrients. 2018;10. doi:10.3390/nu10101460
- Schüller ÁK, Mena Canata DA, Hackenhaar FS, Engers VK, Heemann FM, et al. Effects of lipoic acid and n-3 long-chain polyunsaturated fatty acid on the liver ovariectomized rat model of menopause. Pharmacol Rep. 2018;70:263. doi:10.1016/j.pharep.2017.10.006
- Cianci A, Maiolino L, Giunta G, Rapisarda AMC, Di Mauro P, et al. Neurovegetative disorders of perimenopausal women treated with docosahexaenoic acid (DHA, 625 mg). Gynecol Endocrinol. 2017;33:980. doi:10.1080/09513590.2017.1334200
- Fonolla-Joya J, Reyes-García R, García-Martín A, López-Huertas E, Muñoz-Torres M. Daily Intake of Milk Enriched with n-3 Fatty Acids, Oleic Acid, and Calcium Improves Metabolic and Bone Biomarkers in Postmenopausal Women. J Am Coll Nutr. 2016;35:529.
- Jin Y, Kim TH, Park Y. Association between erythrocyte levels of n-3 polyunsaturated fatty acids and depression in postmenopausal women using or not using hormone therapy. Menopause. 2016;23:1012. doi:10.1097/GME.0000000000000667
- Alves Luzia L, Mendes Aldrighi J, Teixeira Damasceno NR, Rodrigues Sampaio G, Aparecida Manólio Soares R, et al. FISH OIL AND VITAMIN E CHANGE LIPID PROFILES AND ANTI-LDL-ANTIBODIES IN TWO DIFFERENT ETHNIC GROUPS OF WOMEN TRANSITIONING THROUGH MENOPAUSE. Nutr Hosp. 2015;32:165. doi:10.3305/nh.2015.32.1.9079
- Dong H, Hutchins-Wiese H, Kleppinger A, Annis K, Liva E, et al. Effects of Omega-3 Polyunsaturated Fatty Acid Supplementation on Bone Turnover in Older Women. Int J Vitam Nutr Res. 2014;84:124. doi:10.1024/0300-9831/a000199
- Guo L, Nan Y, Liang K, Yao L, Li J. Association between polyunsaturated fatty acid intake and estradiol levels among U.S. women. Front Nutr. 2024;11:1500705. doi:10.3389/fnut.2024.1500705
- So J, Yao JH, Magadmi R, Matthan NR, Lamon-Fava S. Sex differences in lipid mediators derived from omega-3 fatty acids in older individuals with low-grade chronic inflammation. Prostaglandins Leukot Essent Fatty Acids. 2024;203:102655. doi:10.1016/j.plefa.2024.102655
- Cohen LS, Joffe H, Guthrie KA, Ensrud KE, Freeman M, et al. Efficacy of omega-3 for vasomotor symptoms treatment: a randomized controlled trial. Menopause. 2014;21:347. doi:10.1097/GME.0b013e31829e40b8
- Hutchins-Wiese HL, Kleppinger A, Annis K, Liva E, Lammi-Keefe CJ, et al. The impact of supplemental n-3 long chain polyunsaturated fatty acids and dietary antioxidants on physical performance in postmenopausal women. J Nutr Health Aging. 2013;17:76. doi:10.1007/s12603-012-0415-3
- Scuderi G, Contestabile MT, Gagliano C, Iacovello D, Scuderi L, et al. Effects of phytoestrogen supplementation in postmenopausal women with dry eye syndrome: a randomized clinical trial. Can J Ophthalmol. 2012;47:489. doi:10.1016/j.jcjo.2012.08.019
