' 
![]()
SCIENTIFIC SCORE
Possibly Effective
Based on 23 Researches
7.5
USERS' SCORE
Good
Based on 8 Reviews
8.7
Supplement Facts
Serving Size: 1 Softgel
Amount Per Serving
%DV
Calories
10
Total Fat
1 g
1%*
Polyunsaturated Fat
1 g
†
Fish Oil Concentrate
1 g (1,000 mg)
†
Docosahexaenoic Acid (DHA)
500 mg
†
Eicosapentaenoic Acid (EPA)
250 mg
†
Top Medical Research Studies
9.5
Eicosapentaenoic acid helps migraines
A 12-week randomized double-blind clinical trial of eicosapentaenoic acid intervention in episodic migraine.
Directly addresses EPA efficacy
We conducted a thorough investigation into how eicosapentaenoic acid (EPA) can impact episodic migraines. In a carefully designed study, we gathered 70 participants who experienced these migraines and divided them into two groups. One group received a high dose of EPA, while the other was given a placebo. This approach ensured that we could see the true effects of EPA without bias.
After 12 weeks, the results were compelling. We noticed that those taking EPA had significantly fewer migraine days compared to the placebo group. In fact, participants on EPA reported an average reduction of 4.4 days per month, while those on the placebo had barely any change. The EPA group also experienced less need for acute headache medication and marked improvements in headache severity, disability, anxiety, depression, and overall quality of life.
Perhaps most striking was how particularly beneficial EPA seemed to be for female participants. Overall, the study demonstrated that high-dose EPA not only helped reduce the frequency and severity of migraines but also positively influenced the psychological aspects of living with migraines.
This suggests that incorporating EPA into migraine management could be a valuable option for those suffering from episodic migraines, especially as there were no major adverse effects reported.
After 12 weeks, the results were compelling. We noticed that those taking EPA had significantly fewer migraine days compared to the placebo group. In fact, participants on EPA reported an average reduction of 4.4 days per month, while those on the placebo had barely any change. The EPA group also experienced less need for acute headache medication and marked improvements in headache severity, disability, anxiety, depression, and overall quality of life.
Perhaps most striking was how particularly beneficial EPA seemed to be for female participants. Overall, the study demonstrated that high-dose EPA not only helped reduce the frequency and severity of migraines but also positively influenced the psychological aspects of living with migraines.
This suggests that incorporating EPA into migraine management could be a valuable option for those suffering from episodic migraines, especially as there were no major adverse effects reported.
Read More
9.5
Omega-3s effectively reduce migraines
High Dosage Omega-3 Fatty Acids Outperform Existing Pharmacological Options for Migraine Prophylaxis: A Network Meta-Analysis.
Directly addresses migraine treatment
We explored the potential of eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) as effective treatments for preventing migraines. In a comprehensive analysis of 40 randomized controlled trials involving over 6,600 participants, we compared high doses of these omega-3 fatty acids with other commonly prescribed migraine medications.
Our findings revealed that higher dosages of EPA/DHA resulted in significant decreases in both the frequency and severity of migraines compared to a placebo. Specifically, we observed a notable standardized mean difference in migraine frequency and severity, indicating these omega-3s might be a more effective option than current medications.
Moreover, the acceptance rates of this treatment were promising, suggesting that individuals found it easier to tolerate compared to traditional migraine drugs. This evidence supports the idea that high dosage EPA/DHA could be a leading choice for migraine prevention, potentially offering a safer and more effective alternative for many patients.
Our findings revealed that higher dosages of EPA/DHA resulted in significant decreases in both the frequency and severity of migraines compared to a placebo. Specifically, we observed a notable standardized mean difference in migraine frequency and severity, indicating these omega-3s might be a more effective option than current medications.
Moreover, the acceptance rates of this treatment were promising, suggesting that individuals found it easier to tolerate compared to traditional migraine drugs. This evidence supports the idea that high dosage EPA/DHA could be a leading choice for migraine prevention, potentially offering a safer and more effective alternative for many patients.
Read More
9
Eicosapentaenoic acid reduces migraines
The relationship between different fatty acids intake and frequency of migraine attacks.
Direct focus on EPA's effects
We investigated how the intake of eicosapentaenoic acid (EPA), a type of omega-3 fatty acid, might affect the frequency of migraine attacks. In a study involving 105 migraine patients aged 15 to 50, we examined their usual dietary habits through a food frequency questionnaire and tracked their migraine occurrences over a month.
Our findings revealed a notable trend: lower consumption of EPA was tied to an increased number of migraine attacks. Specifically, participants with reduced EPA intake experienced a higher frequency of migraines, with data indicating a significant statistical relationship. We also found that this connection held true for both men and women alike, emphasizing the potential importance of dietary choices in managing migraines.
Conversely, we did not observe any significant link between saturated fatty acids (SFA) and migraine frequency, suggesting that not all dietary fats impact migraines the same way. Overall, our results point to a promising association between omega-3 fatty acids, particularly EPA, and reduced migraine attacks, inviting further research to deepen our understanding of this relationship.
Our findings revealed a notable trend: lower consumption of EPA was tied to an increased number of migraine attacks. Specifically, participants with reduced EPA intake experienced a higher frequency of migraines, with data indicating a significant statistical relationship. We also found that this connection held true for both men and women alike, emphasizing the potential importance of dietary choices in managing migraines.
Conversely, we did not observe any significant link between saturated fatty acids (SFA) and migraine frequency, suggesting that not all dietary fats impact migraines the same way. Overall, our results point to a promising association between omega-3 fatty acids, particularly EPA, and reduced migraine attacks, inviting further research to deepen our understanding of this relationship.
Read More
Most Useful Reviews
8.8
Helpful migraine relief
Best! I love this fish oil! It has undoubtedly rejuvenated my skin, which has become more elastic and smoother. At 56, post-menopause, my skin was fading despite hormonal treatments. This supplement, which I call “fish”, has saved my skin, hair, and nails. My sister’s thin hair has become stronger too. The high docosahexaenoic acid content is great for cardiovascular health and brain function. My migraines have reduced significantly. I highly recommend it, but remember to consult your doctor about the dosage.
Read More
8.8
Omega 3 benefits
I’ve been taking Omega 3 for many years after a stroke and for migraines, and it truly is our lifeguard. I bought this Omega for its highly valued acid content. My husband and I take it for general health rather than specific effects, but I recommend it wholeheartedly.
Read More
10
Migraine cure
Excellent! It’s the only thing that effectively alleviates my migraines. I take two to three at once, and within an hour or two, my migraine subsides. It’s important to note that this is for real migraines, which do not respond to common pain relief.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 23 Researches
7.5
9.5
Omega-3s effective for migraine
High Dosage Omega-3 Fatty Acids Outperform Existing Pharmacological Options for Migraine Prophylaxis: A Network Meta-Analysis.
Overall study shows positive results
We dug into how docosahexaenoic acid (DHA), along with eicosapentaenoic acid (EPA), can help with migraine management. Through a comprehensive analysis of 40 randomized controlled trials involving over 6,600 participants, we compared various treatments for migraine prevention. Our focus was on the effectiveness and acceptability of high doses of DHA and EPA against other standard medications.
What we found was quite intriguing. Supplementing with high doses of EPA and DHA significantly reduced the frequency of migraines as compared to placebo treatments. In fact, our analysis revealed a notable decrease in migraine severity as well. Not only that, but those using high-dose omega-3s reported favorable experiences with treatment, showcasing a high level of acceptability.
This compelling evidence suggests that high doses of DHA and EPA can serve as a premier option for preventing migraines. Their effectiveness and tolerability make them an attractive choice for those seeking relief. The potential of omega-3 supplementation in this context opens new avenues for migraine management that are worth exploring further.
What we found was quite intriguing. Supplementing with high doses of EPA and DHA significantly reduced the frequency of migraines as compared to placebo treatments. In fact, our analysis revealed a notable decrease in migraine severity as well. Not only that, but those using high-dose omega-3s reported favorable experiences with treatment, showcasing a high level of acceptability.
This compelling evidence suggests that high doses of DHA and EPA can serve as a premier option for preventing migraines. Their effectiveness and tolerability make them an attractive choice for those seeking relief. The potential of omega-3 supplementation in this context opens new avenues for migraine management that are worth exploring further.
Read More
9.5
Eicosapentaenoic acid helps migraines
A 12-week randomized double-blind clinical trial of eicosapentaenoic acid intervention in episodic migraine.
Directly addresses EPA efficacy
We conducted a thorough investigation into how eicosapentaenoic acid (EPA) can impact episodic migraines. In a carefully designed study, we gathered 70 participants who experienced these migraines and divided them into two groups. One group received a high dose of EPA, while the other was given a placebo. This approach ensured that we could see the true effects of EPA without bias.
After 12 weeks, the results were compelling. We noticed that those taking EPA had significantly fewer migraine days compared to the placebo group. In fact, participants on EPA reported an average reduction of 4.4 days per month, while those on the placebo had barely any change. The EPA group also experienced less need for acute headache medication and marked improvements in headache severity, disability, anxiety, depression, and overall quality of life.
Perhaps most striking was how particularly beneficial EPA seemed to be for female participants. Overall, the study demonstrated that high-dose EPA not only helped reduce the frequency and severity of migraines but also positively influenced the psychological aspects of living with migraines.
This suggests that incorporating EPA into migraine management could be a valuable option for those suffering from episodic migraines, especially as there were no major adverse effects reported.
After 12 weeks, the results were compelling. We noticed that those taking EPA had significantly fewer migraine days compared to the placebo group. In fact, participants on EPA reported an average reduction of 4.4 days per month, while those on the placebo had barely any change. The EPA group also experienced less need for acute headache medication and marked improvements in headache severity, disability, anxiety, depression, and overall quality of life.
Perhaps most striking was how particularly beneficial EPA seemed to be for female participants. Overall, the study demonstrated that high-dose EPA not only helped reduce the frequency and severity of migraines but also positively influenced the psychological aspects of living with migraines.
This suggests that incorporating EPA into migraine management could be a valuable option for those suffering from episodic migraines, especially as there were no major adverse effects reported.
Read More
9.5
Omega-3s effectively reduce migraines
High Dosage Omega-3 Fatty Acids Outperform Existing Pharmacological Options for Migraine Prophylaxis: A Network Meta-Analysis.
Directly addresses migraine treatment
We explored the potential of eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) as effective treatments for preventing migraines. In a comprehensive analysis of 40 randomized controlled trials involving over 6,600 participants, we compared high doses of these omega-3 fatty acids with other commonly prescribed migraine medications.
Our findings revealed that higher dosages of EPA/DHA resulted in significant decreases in both the frequency and severity of migraines compared to a placebo. Specifically, we observed a notable standardized mean difference in migraine frequency and severity, indicating these omega-3s might be a more effective option than current medications.
Moreover, the acceptance rates of this treatment were promising, suggesting that individuals found it easier to tolerate compared to traditional migraine drugs. This evidence supports the idea that high dosage EPA/DHA could be a leading choice for migraine prevention, potentially offering a safer and more effective alternative for many patients.
Our findings revealed that higher dosages of EPA/DHA resulted in significant decreases in both the frequency and severity of migraines compared to a placebo. Specifically, we observed a notable standardized mean difference in migraine frequency and severity, indicating these omega-3s might be a more effective option than current medications.
Moreover, the acceptance rates of this treatment were promising, suggesting that individuals found it easier to tolerate compared to traditional migraine drugs. This evidence supports the idea that high dosage EPA/DHA could be a leading choice for migraine prevention, potentially offering a safer and more effective alternative for many patients.
Read More
9
Dietary intervention alleviates headaches
Targeted alteration of dietary n-3 and n-6 fatty acids for the treatment of chronic headaches: a randomized trial.
Study shows mixed benefits
We conducted a thorough investigation into how dietary adjustments, particularly focusing on the balance of omega-3 and omega-6 fatty acids, can help reduce the frequency and intensity of chronic headaches, which are often debilitating for many individuals. Our study involved a randomized, controlled trial with participants who were experiencing chronic daily headaches. After a four-week pre-intervention phase, we divided them into two groups, one receiving a high omega-3 plus low omega-6 dietary intervention and the other following a lower omega-6 intake only.
Throughout the 12-week intervention, we observed that those in the high omega-3 group not only reported significant improvements in their headache impact scores but also experienced fewer headache days and reduced headache hours per day. One of the key findings was the increased levels of specific antinociceptive biomarkers related to omega-3 fatty acids, which suggests that enhancing omega-3 intake can alter pain-relieving pathways in the body.
Although the study highlighted the benefits of this dietary approach, it’s important to note that isolating the specific impact of docosahexaenoic acid (DHA) alone was challenging due to the combined dietary changes implemented. Nevertheless, the general evidence suggests that shifting towards more omega-3 fatty acids while lowering omega-6 can lead to meaningful relief from chronic headaches, enhancing not only physical comfort but also the quality of life for individuals suffering from migraines.
Throughout the 12-week intervention, we observed that those in the high omega-3 group not only reported significant improvements in their headache impact scores but also experienced fewer headache days and reduced headache hours per day. One of the key findings was the increased levels of specific antinociceptive biomarkers related to omega-3 fatty acids, which suggests that enhancing omega-3 intake can alter pain-relieving pathways in the body.
Although the study highlighted the benefits of this dietary approach, it’s important to note that isolating the specific impact of docosahexaenoic acid (DHA) alone was challenging due to the combined dietary changes implemented. Nevertheless, the general evidence suggests that shifting towards more omega-3 fatty acids while lowering omega-6 can lead to meaningful relief from chronic headaches, enhancing not only physical comfort but also the quality of life for individuals suffering from migraines.
Read More
9
Eicosapentaenoic acid reduces migraines
The relationship between different fatty acids intake and frequency of migraine attacks.
Direct focus on EPA's effects
We investigated how the intake of eicosapentaenoic acid (EPA), a type of omega-3 fatty acid, might affect the frequency of migraine attacks. In a study involving 105 migraine patients aged 15 to 50, we examined their usual dietary habits through a food frequency questionnaire and tracked their migraine occurrences over a month.
Our findings revealed a notable trend: lower consumption of EPA was tied to an increased number of migraine attacks. Specifically, participants with reduced EPA intake experienced a higher frequency of migraines, with data indicating a significant statistical relationship. We also found that this connection held true for both men and women alike, emphasizing the potential importance of dietary choices in managing migraines.
Conversely, we did not observe any significant link between saturated fatty acids (SFA) and migraine frequency, suggesting that not all dietary fats impact migraines the same way. Overall, our results point to a promising association between omega-3 fatty acids, particularly EPA, and reduced migraine attacks, inviting further research to deepen our understanding of this relationship.
Our findings revealed a notable trend: lower consumption of EPA was tied to an increased number of migraine attacks. Specifically, participants with reduced EPA intake experienced a higher frequency of migraines, with data indicating a significant statistical relationship. We also found that this connection held true for both men and women alike, emphasizing the potential importance of dietary choices in managing migraines.
Conversely, we did not observe any significant link between saturated fatty acids (SFA) and migraine frequency, suggesting that not all dietary fats impact migraines the same way. Overall, our results point to a promising association between omega-3 fatty acids, particularly EPA, and reduced migraine attacks, inviting further research to deepen our understanding of this relationship.
Read More
User Reviews
USERS' SCORE
Good
Based on 8 Reviews
8.7
10
Migraine cure
Excellent! It’s the only thing that effectively alleviates my migraines. I take two to three at once, and within an hour or two, my migraine subsides. It’s important to note that this is for real migraines, which do not respond to common pain relief.
9.5
Effective for migraines
I have been taking Omega 3 double concentration for over two weeks now. Previously, I used lower concentrations, but this higher ratio of DHA-500 is particularly beneficial for brain health and significantly aids in migraine relief. Thank you to the manufacturer!
9.5
Migraine relief achieved
I have been taking DHA500 for over nine months, with two capsules daily. I immediately felt more energetic and sporty, and my skin remained moisturised despite frequent washing. My hair is less split and more vibrant. I fell ill less often this year, and even during mild Covid, I largely escaped severe symptoms thanks to fish oil. Migraines during PMS have disappeared too. I’m very pleased and intend to continue.
Read More
9
Migraines improved
These capsules are easy to swallow, reasonably sized, and do not repeat. The high EPA content was recommended for my migraines and arthritis, and I can attest that they’ve helped with both after taking two daily. I definitely recommend them!
8.8
Helpful migraine relief
Best! I love this fish oil! It has undoubtedly rejuvenated my skin, which has become more elastic and smoother. At 56, post-menopause, my skin was fading despite hormonal treatments. This supplement, which I call “fish”, has saved my skin, hair, and nails. My sister’s thin hair has become stronger too. The high docosahexaenoic acid content is great for cardiovascular health and brain function. My migraines have reduced significantly. I highly recommend it, but remember to consult your doctor about the dosage.
Read More
