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NOW Supplements Selenium
SCIENTIFIC SCORE
Possibly Effective
Based on 15 Researches
7.9
USERS' SCORE
Good
Based on 13 Reviews
8.7
Supplement Facts
Serving Size: 1 Tablet
Amount Per Serving
%DV
Selenium (elemental) (from 20 mg L-Selenomethionine)
100 mcg
182%

Top Medical Research Studies

9.5
Selenium nanoparticles reduce liver toxicity
Chitosan-encapsulated selenium nanoparticles alleviate CCl induced hepatotoxicity through synergistically modulating NF-κB and Nrf2 signaling pathways and regulating Bcl-2 and Caspase-3 expression: A comprehensive study with multiple regression analysis.
High relevance to liver toxicity
We investigated how selenium nanoparticles (Se-NPs) and chitosan-encapsulated selenium nanoparticles (Se-CS-NPs) can mitigate liver toxicity induced by carbon tetrachloride (CCl) in rats. In our study, eighty rats were divided into eight groups, including placebo and control.

The findings indicated that both forms of selenium helped in reducing liver damage by influencing key biological markers. Notably, while selenium was effective, encapsulating it with chitosan did not provide additional benefits. Overall, these nanoparticles could be a valuable treatment option against liver toxicity.
Read More
8
Potential selenium benefits on liver
Selenium nanoparticles alleviates cadmium induced hepatotoxicity by inhibiting ferroptosis and oxidative stress in vivo and in vitro.
High relevance for hepatotoxicity research
We examined how selenium nanoparticles might help combat liver damage caused by cadmium, a dangerous environmental toxin. By studying both animal models and liver cells, we found that these nanoparticles could reduce cell injuries linked to a damaging process called ferroptosis.

Our findings indicated that achieving this protective effect involves enhancing certain liver enzyme activities and altering several protein levels associated with oxidative stress. Overall, while selenium shows promise in mitigating liver damage, particularly against cadmium toxicity, further research could better clarify its mechanisms and potential benefits.
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9
Selenium aids in liver protection
Selenium Attenuates Ethanol-induced Hepatocellular Injury by Regulating Ferroptosis and Apoptosis.
Significant findings on liver health
We explored the potential of selenium in addressing liver damage caused by alcohol. The study employed both in vitro and in vivo methods to assess how selenium affects liver cells exposed to ethanol.

Our findings indicated that selenium improved cell viability, reduced oxidative stress markers, and altered certain protein expressions related to cell death. In particular, selenomethionine showed a notable impact in protecting liver cells.

Overall, selenium appears promising for alleviating ethanol-induced liver injury by regulating important cellular processes. However, results suggest that further research is needed to fully understand its effectiveness.
Read More

Most Useful Reviews

9.5
Liver health improved
Selenium, along with N-acetylcysteine, aids glutathione production. Although children can produce it, those over 60 struggle. I originally bought N-Acetylcysteine, which is pricey, but selenium is affordable and ideal for daily use. Since adding it with zinc, I've notably improved my liver function, and I rarely catch colds.
Read More
8.8
Improved well-being
I heard this is good for detoxifying the liver, so I bought it for my partner with a weak liver. After starting to drink it, I felt much better. I used to have a high fever occasionally, but that has subsided. I believe it's effective, and I appreciate that it is reasonably priced.
Read More
7.5
Good nutritional supplement
This is an excellent nutritional supplement that benefits the liver, featuring natural ingredients and attractive packaging.
Read More

Medical Researches

SCIENTIFIC SCORE
Possibly Effective
Based on 15 Researches
7.9
  • All Researches
9.5
Selenium nanoparticles reduce liver toxicity
Chitosan-encapsulated selenium nanoparticles alleviate CCl induced hepatotoxicity through synergistically modulating NF-κB and Nrf2 signaling pathways and regulating Bcl-2 and Caspase-3 expression: A comprehensive study with multiple regression analysis.
High relevance to liver toxicity
We investigated how selenium nanoparticles (Se-NPs) and chitosan-encapsulated selenium nanoparticles (Se-CS-NPs) can mitigate liver toxicity induced by carbon tetrachloride (CCl) in rats. In our study, eighty rats were divided into eight groups, including placebo and control.

The findings indicated that both forms of selenium helped in reducing liver damage by influencing key biological markers. Notably, while selenium was effective, encapsulating it with chitosan did not provide additional benefits. Overall, these nanoparticles could be a valuable treatment option against liver toxicity.
Read More
9
Selenium and CoQ improve liver health
Coenzyme Q and Selenium Co-Supplementation Alleviate Methionine Choline-Deficient Diet-Induced Metabolic Dysfunction-Associated Steatohepatitis in Mice.
High relevance for liver treatment
We aimed to investigate the role of selenium and coenzyme Q in addressing liver damage caused by a methionine choline-deficient diet in mice. Over four weeks, mice receiving the combination treatment showed significant reductions in liver inflammation, fibrosis, and oxidative stress.

The results suggested that this combined supplementation might hold therapeutic potential against metabolic dysfunction-associated liver injury. While our findings are promising, they are based on an animal model, and further research is necessary to explore their implications for human liver disease.
Read More
9
Selenium enhances liver health
Glutathione and Selenium Supplementation Attenuates Liver Injury in Diethylnitrosamine-Induced Hepatocarcinogenic Mice by Enhancing Glutathione-Related Antioxidant Capacities.
High relevance to liver research
We set out to investigate if selenium, along with glutathione, can help reduce liver injury caused by a cancer-inducing substance in mice. Over 20 weeks, we divided male mice into different groups, some receiving selenium and others just glutathione, while monitoring their liver function.

Our findings revealed that both supplements significantly improved liver conditions and antioxidant levels. Interestingly, adding selenium to glutathione treatment worked even better, enhancing the liver’s ability to handle oxidative stress. Overall, selenium appears to be a promising ally in supporting liver health and reducing injury.
Read More
9
Selenium aids in liver protection
Selenium Attenuates Ethanol-induced Hepatocellular Injury by Regulating Ferroptosis and Apoptosis.
Significant findings on liver health
We explored the potential of selenium in addressing liver damage caused by alcohol. The study employed both in vitro and in vivo methods to assess how selenium affects liver cells exposed to ethanol.

Our findings indicated that selenium improved cell viability, reduced oxidative stress markers, and altered certain protein expressions related to cell death. In particular, selenomethionine showed a notable impact in protecting liver cells.

Overall, selenium appears promising for alleviating ethanol-induced liver injury by regulating important cellular processes. However, results suggest that further research is needed to fully understand its effectiveness.
Read More
8
Selenium's effects on liver fibrosis
Antioxidant and hepatic fibrosis-alleviating effects of selenium-modified Bletilla striata polysaccharide.
Moderately relevant study findings
We investigated whether selenium-modified Bletilla striata polysaccharide (Se-BSP) could effectively reduce liver fibrosis. Our findings revealed that Se-BSP not only improved its antioxidant properties but also showed greater efficacy in alleviating liver fibrosis compared to its unmodified version at a specific concentration. This study underscores the potential of Se-BSP as a promising treatment for liver fibrosis, a condition that can lead to more severe liver diseases.
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User Reviews

USERS' SCORE
Good
Based on 13 Reviews
8.7
  • All Reviews
  • Positive Reviews
  • Negative Reviews
9.5
Liver health improved
Selenium, along with N-acetylcysteine, aids glutathione production. Although children can produce it, those over 60 struggle. I originally bought N-Acetylcysteine, which is pricey, but selenium is affordable and ideal for daily use. Since adding it with zinc, I've notably improved my liver function, and I rarely catch colds.
Read More
8.8
Improved well-being
I heard this is good for detoxifying the liver, so I bought it for my partner with a weak liver. After starting to drink it, I felt much better. I used to have a high fever occasionally, but that has subsided. I believe it's effective, and I appreciate that it is reasonably priced.
Read More
7.5
Good nutritional supplement
This is an excellent nutritional supplement that benefits the liver, featuring natural ingredients and attractive packaging.
8.8
Improved liver function
Excellent! I take one tablet at night to detoxify my body and enhance liver function, and I feel refreshed by morning. I’ve noticed no side effects and will continue taking it. Along with exercise, I believe this has helped me lose body fat.
7.5
Aids liver detox
Selenium is a promising liver detoxifier, and I've incorporated it into my routine. I take one tablet daily with oily meals, and I feel my skin has improved. While seafood is rich in mercury, selenium may assist in its excretion. I'm curious about the overdose potential with supplements.
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