Last update
3/14/2026
Reviewed By
Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 2 Researches
7
USERS' SCORE
Good
Based on 2 Reviews
8.6
Supplement Facts
Serving Size: 1 Tablet
Amount Per Serving
%DV
Selenium (elemental) (from 20 mg L-Selenomethionine)
100 mcg
182%
Top Medical Research Studies
7
Selenium showed no significant effects
We examined a clinical trial that investigates whether selenium supplementation can help alleviate migraine symptoms. In this randomized, double-blinded study, 72 patients were divided into two groups: one received a daily selenium supplement while the other got a placebo, all over 12 weeks.
We tracked headache severity, frequency, and mental health markers like anxiety and depression, alongside measuring oxidative stress biomarkers. Despite the hopes for selenium’s antioxidant benefits, the trial did not find significant improvements in migraine symptoms or related health measures.
We tracked headache severity, frequency, and mental health markers like anxiety and depression, alongside measuring oxidative stress biomarkers. Despite the hopes for selenium’s antioxidant benefits, the trial did not find significant improvements in migraine symptoms or related health measures.
Read More
7
We assessed the link between selenium levels and migraine in a case-control study involving 31 migraine patients and 30 healthy controls. Our findings revealed that migraine patients had significantly lower selenium levels and higher levels of malondialdehyde, a marker of oxidative stress.
Intriguingly, those with the lowest selenium levels were about eleven times more likely to experience migraines compared to those with the highest levels. However, no significant differences were observed in total antioxidant capacity between the two groups, indicating that while selenium appears connected to migraine risk, it does not directly reduce migraine frequency.
Intriguingly, those with the lowest selenium levels were about eleven times more likely to experience migraines compared to those with the highest levels. However, no significant differences were observed in total antioxidant capacity between the two groups, indicating that while selenium appears connected to migraine risk, it does not directly reduce migraine frequency.
Read More
Most Useful Reviews
9
Migraine relief achieved
Fine! I appreciated Selenium from this company immensely; my family and I enjoy it together. Alongside, we take Omega and D3 with K2, as well as Yodomarin and Aevit from Russian manufacturers. Regarding efficacy, I was utterly exhausted for a long period, lying in bed without the strength or motivation for daily chores. Now, I wake up refreshed and am active throughout the day! After suffering from migraines for the past four years, particularly with weather changes, I found relief once I introduced Selenium and D3K2. I'm also pleased to say hangovers are a thing of the past; I wake up fresher and more cheerful than ever. I highly recommend staying active and healthy!
Read More
9
Effective migraine management
Great! It normalises sleep with regular intake of two capsules and significantly improves my migraines. I take my usual pills along with additional magnesium, which helps the migraine to disappear within a couple of hours rather than incapacitating me for half a day as it used to. The frequency has also lessened. With consistent magnesium consumption, I handle PMS and menstruation more easily; I do not get irritable, and I can sometimes avoid painkillers entirely. Chronic nasopharyngeal pain rarely worsens, but it’s challenging to attribute benefits solely to magnesium since I also take omega-3, serrapeptase, and resveratrol. However, the effect of internal collagen intake is noticeable, and I was thoroughly surprised by this. We experienced no allergies or rashes. The quality is exceptional, and the ingredients are all-natural.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 2 Researches
7
- All Researches
7
Selenium showed no significant effects
We examined a clinical trial that investigates whether selenium supplementation can help alleviate migraine symptoms. In this randomized, double-blinded study, 72 patients were divided into two groups: one received a daily selenium supplement while the other got a placebo, all over 12 weeks.
We tracked headache severity, frequency, and mental health markers like anxiety and depression, alongside measuring oxidative stress biomarkers. Despite the hopes for selenium’s antioxidant benefits, the trial did not find significant improvements in migraine symptoms or related health measures.
We tracked headache severity, frequency, and mental health markers like anxiety and depression, alongside measuring oxidative stress biomarkers. Despite the hopes for selenium’s antioxidant benefits, the trial did not find significant improvements in migraine symptoms or related health measures.
Read More
7
We assessed the link between selenium levels and migraine in a case-control study involving 31 migraine patients and 30 healthy controls. Our findings revealed that migraine patients had significantly lower selenium levels and higher levels of malondialdehyde, a marker of oxidative stress.
Intriguingly, those with the lowest selenium levels were about eleven times more likely to experience migraines compared to those with the highest levels. However, no significant differences were observed in total antioxidant capacity between the two groups, indicating that while selenium appears connected to migraine risk, it does not directly reduce migraine frequency.
Intriguingly, those with the lowest selenium levels were about eleven times more likely to experience migraines compared to those with the highest levels. However, no significant differences were observed in total antioxidant capacity between the two groups, indicating that while selenium appears connected to migraine risk, it does not directly reduce migraine frequency.
Read More
User Reviews
USERS' SCORE
Good
Based on 2 Reviews
8.6
- All Reviews
- Positive Reviews
- Negative Reviews
9
Migraine relief achieved
Fine! I appreciated Selenium from this company immensely; my family and I enjoy it together. Alongside, we take Omega and D3 with K2, as well as Yodomarin and Aevit from Russian manufacturers. Regarding efficacy, I was utterly exhausted for a long period, lying in bed without the strength or motivation for daily chores. Now, I wake up refreshed and am active throughout the day! After suffering from migraines for the past four years, particularly with weather changes, I found relief once I introduced Selenium and D3K2. I'm also pleased to say hangovers are a thing of the past; I wake up fresher and more cheerful than ever. I highly recommend staying active and healthy!
Read More
9
Effective migraine management
Great! It normalises sleep with regular intake of two capsules and significantly improves my migraines. I take my usual pills along with additional magnesium, which helps the migraine to disappear within a couple of hours rather than incapacitating me for half a day as it used to. The frequency has also lessened. With consistent magnesium consumption, I handle PMS and menstruation more easily; I do not get irritable, and I can sometimes avoid painkillers entirely. Chronic nasopharyngeal pain rarely worsens, but it’s challenging to attribute benefits solely to magnesium since I also take omega-3, serrapeptase, and resveratrol. However, the effect of internal collagen intake is noticeable, and I was thoroughly surprised by this. We experienced no allergies or rashes. The quality is exceptional, and the ingredients are all-natural.
Read More
Frequently Asked Questions
9
Effective migraine management
Great! It normalises sleep with regular intake of two capsules and significantly improves my migraines. I take my usual pills along with additional magnesium, which helps the migraine to disappear within a couple of hours rather than incapacitating me for half a day as it used to. The frequency has also lessened. With consistent magnesium consumption, I handle PMS and menstruation more easily; I do not get irritable, and I can sometimes avoid painkillers entirely. Chronic nasopharyngeal pain rarely worsens, but it’s challenging to attribute benefits solely to magnesium since I also take omega-3, serrapeptase, and resveratrol. However, the effect of internal collagen intake is noticeable, and I was thoroughly surprised by this. We experienced no allergies or rashes. The quality is exceptional, and the ingredients are all-natural.
9
Migraine relief achieved
Fine! I appreciated Selenium from this company immensely; my family and I enjoy it together. Alongside, we take Omega and D3 with K2, as well as Yodomarin and Aevit from Russian manufacturers. Regarding efficacy, I was utterly exhausted for a long period, lying in bed without the strength or motivation for daily chores. Now, I wake up refreshed and am active throughout the day! After suffering from migraines for the past four years, particularly with weather changes, I found relief once I introduced Selenium and D3K2. I'm also pleased to say hangovers are a thing of the past; I wake up fresher and more cheerful than ever. I highly recommend staying active and healthy!
References
- Balali A, Sadeghi O, Anjom-Shoae J, Rouhani MH, Khorvash F, et al. The effect of selenium supplementation on oxidative stress, clinical symptoms and mental health status in patients with migraine: a study protocol for a double-blinded randomized clinical trial. Trials. 2024;25:209. 10.1186/s13063-024-08018-8
- Talaie A, Jafary H, Faraji F, Malekirad AA. The Serum Oxidative Stress Biomarkers and Selenium Levels in a Group of Migraine Patients Compared with Healthy Controls: a Case-Control Study. Biol Trace Elem Res. 2022;200:4250. 10.1007/s12011-021-03024-2
Data last updated:
