Overview

SCIENTIFIC SCORE
Possibly Effective
Based on 5 Researches
7.4
USERS' SCORE
Moderately Good
Based on 11 Reviews
7.4
Supplement Facts
Serving Size: 1 Veg Capsule
Amount Per Serving
%DV
Iron (elemental) (from 180 mg Ferrous Bisglycinate)(Ferrochel™)
36 mg
200%

Top Medical Research Studies

8
Iron treatment’s impact on bloating
We explored how iron supplementation impacts patients with celiac disease who suffer from iron deficiency anemia, particularly focusing on those unable to tolerate traditional iron sulfate. In this study, patients were divided into two groups: one receiving a new formulation called sucrosomial iron and the other taking iron sulfate.

After a 90-day follow-up, both groups showed significant improvements in hemoglobin levels and overall iron metrics. Interestingly, those taking sucrosomial iron experienced a marked reduction in abdominal symptoms like bloating and pain. They reported feeling a 33% increase in general well-being compared to 21% in the iron sulfate group.

This suggests sucrosomial iron could be a preferable option for individuals with celiac disease who struggle with gastrointestinal discomfort from standard iron treatments. Overall, while both forms of iron supplementation were effective, sucrosomial iron may ease some of the unpleasant side effects commonly associated with iron therapy.
Read More
4
Iron's role in bloating is nuanced
We observed how iron compounds play a pivotal role in the formation of lightweight aggregates (LWAs) during a thermal process. Our work involved heating reservoir sediment pellets at temperatures of 1050 and 1150 degrees Celsius, which resulted in the creation of LWAs with varying densities.

Notably, in the raw sediment, about 59% of the iron was found in the form of Fe(2+). However, most of this iron was oxidized to Fe(3+) during the process, except for the core of the LWAs produced at the higher temperature of 1150 degrees Celsius.

We found that the bloating reactions, particularly one in the core of the 1150 degrees Celsius LWA, were primarily related to the breakdown of iron sulfate (FeSO4) into iron oxide (FeO). This process released gases like SO2, SO3, and O2, but it did not alter the valence state of iron.

Interestingly, we did not observe the commonly accepted mechanism that suggests the reduction of Fe(2)O(3) to FeO triggers bloating with the release of O2. This indicates that while iron is involved in creating LWAs, it does not necessarily enhance bloating in the way traditionally thought.
Read More
We examined how the addition of iron influences the formation of expanded clay aggregates, which are lightweight materials often used in construction. During the study, we utilized iron-free kaolin, a type of clay, as our starting material, and added cork powder for organic carbon along with sodium carbonate as a flux.

Our experimental design involved a statistical approach, allowing us to optimize several important properties such as density, absorption capacity, and mechanical strength. We found that for optimal properties, the mixtures required between 25 and 40 weight percent of iron. Additionally, incorporating 3.5 to 5 weight percent of organic carbon was crucial.

Interestingly, we discovered that the addition of iron caused a much greater expansion of the aggregates—up to 53%—compared to the control samples without iron, which showed only 8% expansion. This suggests that the conditions under which iron reacts lead to different types of changes in the material.

Overall, the results were promising, particularly for iron-containing aggregates, reinforcing the idea that iron plays a significant role in enhancing bloating. Our findings encourage further exploration of these statistical methods in future research projects.
Read More

Most Useful Reviews

9
No bloating experienced
1 people found this helpful
After using two cans, my ferritin levels doubled! I continue to take them regularly with no bloating or discomfort. I highly recommend these.
Read More
9
No more bloating
I've struggled with anaemia since birth. Previously, prescribed iron caused significant stomach issues. After three months on this, I feel energised, happier, and best of all, I have no bloating or stomach pains. I will keep repurchasing this forever.
Read More
9
No bloating reported
This supplement is well-absorbed and does not cause any bloating. I feel great after taking it.
Read More

Medical Researches

SCIENTIFIC SCORE
Possibly Effective
Based on 5 Researches
7.4
  • All Researches
We examined how the addition of iron influences the formation of expanded clay aggregates, which are lightweight materials often used in construction. During the study, we utilized iron-free kaolin, a type of clay, as our starting material, and added cork powder for organic carbon along with sodium carbonate as a flux.

Our experimental design involved a statistical approach, allowing us to optimize several important properties such as density, absorption capacity, and mechanical strength. We found that for optimal properties, the mixtures required between 25 and 40 weight percent of iron. Additionally, incorporating 3.5 to 5 weight percent of organic carbon was crucial.

Interestingly, we discovered that the addition of iron caused a much greater expansion of the aggregates—up to 53%—compared to the control samples without iron, which showed only 8% expansion. This suggests that the conditions under which iron reacts lead to different types of changes in the material.

Overall, the results were promising, particularly for iron-containing aggregates, reinforcing the idea that iron plays a significant role in enhancing bloating. Our findings encourage further exploration of these statistical methods in future research projects.
Read More
8
Probiotics aid iron treatment tolerability
We explored how the addition of a specific probiotic, Lactobacillus plantarum 299v, influences the gastrointestinal effects experienced by patients undergoing oral iron replacement therapy for iron deficiency anemia (IDA). In our study, 295 patients were split into two groups: one received only iron treatment, while the other received iron with the probiotic.

Our findings revealed that adding the probiotic significantly reduced the rate of gastrointestinal issues, such as bloating and abdominal pain, which are common complaints when taking iron supplements. Patients in the group receiving the probiotic experienced gastrointestinal intolerance symptoms at a much lower rate—only 13% compared to 46.5% in the iron-only group.

Not only did the probiotic help with tolerability, but it also seemed to improve iron status markers. For instance, after three months, those taking the probiotic had higher serum iron and transferrin saturation levels, as well as a greater improvement in hemoglobin levels. This points to the potential benefits of probiotics in enhancing the experience of those receiving iron therapy, especially in reducing undesirable side effects like bloating and enhancing overall treatment adherence.
Read More
8
Iron treatment’s impact on bloating
We explored how iron supplementation impacts patients with celiac disease who suffer from iron deficiency anemia, particularly focusing on those unable to tolerate traditional iron sulfate. In this study, patients were divided into two groups: one receiving a new formulation called sucrosomial iron and the other taking iron sulfate.

After a 90-day follow-up, both groups showed significant improvements in hemoglobin levels and overall iron metrics. Interestingly, those taking sucrosomial iron experienced a marked reduction in abdominal symptoms like bloating and pain. They reported feeling a 33% increase in general well-being compared to 21% in the iron sulfate group.

This suggests sucrosomial iron could be a preferable option for individuals with celiac disease who struggle with gastrointestinal discomfort from standard iron treatments. Overall, while both forms of iron supplementation were effective, sucrosomial iron may ease some of the unpleasant side effects commonly associated with iron therapy.
Read More
8
Iron's unclear impact on bloating
We explored the case of a 56-year-old woman who experienced troubling symptoms like epigastric pain, watery diarrhoea, and bloating after starting medications for anxiety and depression.

Upon testing, we found that her blood showed low iron levels and signs of iron-deficiency anaemia. While her treatment included a gluten-free diet, iron supplementation, and loperamide, it's important to note that the study suggests that the combination of treatments made it hard to pinpoint the specific impact of iron on her bloating.

Despite the comprehensive approach, we cannot definitively say that iron treatment alone was effective in reducing her bloating. However, we observed that after her treatment plan, including lifestyle modifications, her symptoms resolved, and a follow-up test showed negative results for blood in her stool.

This indicates a positive response overall, but the link between iron treatment and the bloating specifically remains uncertain.
Read More
4
Iron's role in bloating is nuanced
We observed how iron compounds play a pivotal role in the formation of lightweight aggregates (LWAs) during a thermal process. Our work involved heating reservoir sediment pellets at temperatures of 1050 and 1150 degrees Celsius, which resulted in the creation of LWAs with varying densities.

Notably, in the raw sediment, about 59% of the iron was found in the form of Fe(2+). However, most of this iron was oxidized to Fe(3+) during the process, except for the core of the LWAs produced at the higher temperature of 1150 degrees Celsius.

We found that the bloating reactions, particularly one in the core of the 1150 degrees Celsius LWA, were primarily related to the breakdown of iron sulfate (FeSO4) into iron oxide (FeO). This process released gases like SO2, SO3, and O2, but it did not alter the valence state of iron.

Interestingly, we did not observe the commonly accepted mechanism that suggests the reduction of Fe(2)O(3) to FeO triggers bloating with the release of O2. This indicates that while iron is involved in creating LWAs, it does not necessarily enhance bloating in the way traditionally thought.
Read More

User Reviews

USERS' SCORE
Moderately Good
Based on 11 Reviews
7.4
  • All Reviews
  • Positive Reviews
  • Negative Reviews
9
No bloating experienced
1 people found this helpful
After using two cans, my ferritin levels doubled! I continue to take them regularly with no bloating or discomfort. I highly recommend these.
Read More
9
No more bloating
I've struggled with anaemia since birth. Previously, prescribed iron caused significant stomach issues. After three months on this, I feel energised, happier, and best of all, I have no bloating or stomach pains. I will keep repurchasing this forever.
Read More
9
No bloating reported
This supplement is well-absorbed and does not cause any bloating. I feel great after taking it.
Read More
9
Bloating resolved
After taking these vitamins, I noticed a boost in energy and strength; I no longer feel tired. Bloating and constipation have vanished.
Read More
9
No bloating noted
I love this great product! My family enjoys it too. iHerb is fantastic, providing all I need in one place. My digestion is excellent with no bloating or constipation since I started taking this.
Read More

Frequently Asked Questions

9
Bloating resolved
After taking these vitamins, I noticed a boost in energy and strength; I no longer feel tired. Bloating and constipation have vanished.
7.5
Slight bloating felt
The first week involved slight bloating as my stomach adjusted, but I had no indigestion while following my doctor's advice on consumption.
9
No more bloating
I've struggled with anaemia since birth. Previously, prescribed iron caused significant stomach issues. After three months on this, I feel energised, happier, and best of all, I have no bloating or stomach pains. I will keep repurchasing this forever.
9
No bloating reported
This supplement is well-absorbed and does not cause any bloating. I feel great after taking it.
6
Less bloating noted
2 people found this helpful
I had been searching for iron for ages but was concerned about bloating. It was noted as non-constipating, so I tried it. Initially, I experienced some loose stomach symptoms and bloating, but I expect it to improve over time. However, I’ve noticed less cramping in my legs, which has been an ongoing issue for me. I’m grateful to iHerb for this.
9
No bloating experienced
1 people found this helpful
After using two cans, my ferritin levels doubled! I continue to take them regularly with no bloating or discomfort. I highly recommend these.
4
Iron absorption improvement
I purchased this due to symptoms of iron deficiency, such as dizziness and bruising. It hasn’t made me feel unwell, but those with stomach issues like candida and SIBO may want to steer clear. I experienced significant bloating and low blood sugar. I will follow up after checking my ferritin levels once my stomach feels better!
0
Persistent bloating issue
My ferritin increased, but not as much as expected, going from 50 to 67 in two months. Previously, a cheaper product caused a larger increase. Together with vitamin C and B vitamins, I had hoped for better results, but unfortunately, this also caused bloating.
8
Probiotics aid iron treatment tolerability
We explored how the addition of a specific probiotic, Lactobacillus plantarum 299v, influences the gastrointestinal effects experienced by patients undergoing oral iron replacement therapy for iron deficiency anemia (IDA). In our study, 295 patients were split into two groups: one received only iron treatment, while the other received iron with the probiotic.

Our findings revealed that adding the probiotic significantly reduced the rate of gastrointestinal issues, such as bloating and abdominal pain, which are common complaints when taking iron supplements. Patients in the group receiving the probiotic experienced gastrointestinal intolerance symptoms at a much lower rate—only 13% compared to 46.5% in the iron-only group.

Not only did the probiotic help with tolerability, but it also seemed to improve iron status markers. For instance, after three months, those taking the probiotic had higher serum iron and transferrin saturation levels, as well as a greater improvement in hemoglobin levels. This points to the potential benefits of probiotics in enhancing the experience of those receiving iron therapy, especially in reducing undesirable side effects like bloating and enhancing overall treatment adherence.
8
Iron treatment’s impact on bloating
We explored how iron supplementation impacts patients with celiac disease who suffer from iron deficiency anemia, particularly focusing on those unable to tolerate traditional iron sulfate. In this study, patients were divided into two groups: one receiving a new formulation called sucrosomial iron and the other taking iron sulfate.

After a 90-day follow-up, both groups showed significant improvements in hemoglobin levels and overall iron metrics. Interestingly, those taking sucrosomial iron experienced a marked reduction in abdominal symptoms like bloating and pain. They reported feeling a 33% increase in general well-being compared to 21% in the iron sulfate group.

This suggests sucrosomial iron could be a preferable option for individuals with celiac disease who struggle with gastrointestinal discomfort from standard iron treatments. Overall, while both forms of iron supplementation were effective, sucrosomial iron may ease some of the unpleasant side effects commonly associated with iron therapy.
8
Iron's unclear impact on bloating
We explored the case of a 56-year-old woman who experienced troubling symptoms like epigastric pain, watery diarrhoea, and bloating after starting medications for anxiety and depression.

Upon testing, we found that her blood showed low iron levels and signs of iron-deficiency anaemia. While her treatment included a gluten-free diet, iron supplementation, and loperamide, it's important to note that the study suggests that the combination of treatments made it hard to pinpoint the specific impact of iron on her bloating.

Despite the comprehensive approach, we cannot definitively say that iron treatment alone was effective in reducing her bloating. However, we observed that after her treatment plan, including lifestyle modifications, her symptoms resolved, and a follow-up test showed negative results for blood in her stool.

This indicates a positive response overall, but the link between iron treatment and the bloating specifically remains uncertain.

References

  1. Koker G, Sahinturk Y, Ozcelik Koker G, Coskuner MA, Eren Durmus M, et al. Improved gastrointestinal tolerance and iron status via probiotic use in iron deficiency anaemia patients initiating oral iron replacement: a randomised controlled trial. Br J Nutr. 2024;132:1308. doi:10.1017/S0007114524002757
  2. Moreno-Maroto JM, González-Corrochano B, Martínez-Rodríguez AM, Conde-Sánchez A, Cobo-Ceacero CJ, et al. Analyzing the Role of Fe and Fe in the Formation of Expanded Clay Aggregates. Materials (Basel). 2023;16. doi:10.3390/ma16165623
  3. Elli L, Ferretti F, Branchi F, Tomba C, Lombardo V, et al. Sucrosomial Iron Supplementation in Anemic Patients with Celiac Disease Not Tolerating Oral Ferrous Sulfate: A Prospective Study. Nutrients. 2018;10. doi:10.3390/nu10030330
  4. Yau AH, Xiong W, Ko HH. Collagenous enterocolitis manifesting as watery diarrhoea and iron-deficiency anaemia. BMJ Case Rep. 2015;2015. doi:10.1136/bcr-2015-211200
  5. Wei YL, Lin YY. Role of Fe compounds in light aggregate formation from a reservoir sediment. J Hazard Mater. 2009;171:111. doi:10.1016/j.jhazmat.2009.05.122
image