Medical Researches
Moderately Effective
Based on 2 Researches
Iron treatment in menopause studyDeferasirox improved iron homeostasis and hematopoiesis in ovariectomized rats with iron accumulation.
High relevance to menopause research
We investigated how iron treatment affects iron levels and blood production in rats that underwent ovariectomy, a procedure mimicking menopause. By using Deferasirox, a medication often prescribed for iron overload conditions, we aimed to understand its role in managing iron levels and supporting blood health in this context.
Our study involved sixty-four female Wistar rats divided into several groups. After undergoing surgery to simulate menopause, we induced iron accumulation in them. We then treated some groups with Deferasirox at varying doses and looked into its effects on their health.
We observed that the treatment with Deferasirox led to improved conditions in several key areas. There were noticeable positive changes in the uterine tissue, an increase in white blood cells, and a decrease in harmful iron levels. Moreover, the treatment increased the body’s antioxidant capacity, helping fight oxidative stress commonly seen in menopausal conditions.
Deferasirox also had beneficial effects on bone health and the overall functioning of blood-producing cells. Additionally, it influenced gene expressions related to iron metabolism and blood production. Overall, we found that Deferasirox plays an important role in managing iron and enhancing blood health in rats experiencing conditions similar to menopause.
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We looked into how iron levels affect cognitive performance in women experiencing menopause. Our research involved non-anemic women who had either low or normal iron levels for their age and background. They provided blood samples, underwent MRI scans to assess brain iron levels, and participated in cognitive tasks while we recorded their brain activity through EEG.
What we found was quite interesting. Higher iron status in these women was linked to better cognitive performance and improved brain activity. This included benefits associated with oxygen transport, which is crucial for brain function. However, we didn’t discover any direct connections between iron levels in the blood and the iron present in the brain.
Despite the lack of a clear relationship between systemic and brain iron, our findings suggest that addressing low iron levels during the menopausal transition may help reduce the cognitive struggles, often referred to as "brain fog," that many women experience during this time. So, while the study didn’t evaluate specific iron treatments, it opens the door to thinking about iron status as a factor worth considering for overall cognitive health in menopausal women.
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User Reviews
I've never had issues with haemoglobin until menopause brought heavy bleeding and dizziness. After starting this supplement, I regained strength and my dizziness improved.
I started taking iron supplements when my ferritin was in the thirties. After three months, my level rose to the sixties, which I consider effective. I plan to continue taking it since my meals have not been sufficient, especially during menopause.
Energised daily activities
My ferritin was so low it couldn't be measured, leaving me fatigued. Since taking this iron supplement with vitamin C, I haven't experienced constipation and feel more energetic. Cooking and cleaning are enjoyable again, and I've increased my ferritin levels considerably. I intend to continue this supplement until menopause to help with my anxiety.
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I had been taking female hormones for menopause, but they stopped working, leaving me feeling depressed. After reading Dr. Ishihara's book and trying this iron supplement, I quickly regained my energy and motivation. My hair and nails have improved, and I am very thankful.
Suffering from postpartum depression after my first child, I began taking iron on my doctor’s advice. After a long struggle, my ferritin rose, and my health improved significantly. I was unable to take it during my second pregnancy, but I realised it is essential for me, especially during menopause. Please, don't stop carrying this product, iHerb!
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