Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 1 Research
7
USERS' SCORE
Good
Based on 4 Reviews
8.2
Supplement Facts
Serving Size: 1 Softgel
Amount Per Serving
%DV
Ubiquinol (Kaneka Ubiquinol™) (Reduced Form CoQ10)
100 mg
**
Top Medical Research Studies
7
Ubiquinol shows partial benefits
We explored the impact of ubiquinol on pulmonary hypertension using a model that mimics this serious condition. In our study, rats were injected with monocrotaline, a substance known to induce pulmonary hypertension. Over the course of the experiment, we provided various groups of these rats with different treatments, including solubilized ubiquinol and selenium, to see how these substances could protect against the effects of the disease.
The results were quite enlightening. We observed that ubiquinol administered intravenously had a protective effect, especially in male rats. This treatment reduced the right ventricle hypertrophy and lung mass commonly associated with elevated blood pressure in the lungs. Interestingly, when we combined ubiquinol with selenium, we found a less severe increase in right ventricle systolic pressure in males but not in females, indicating a sex-dependent effect that suggests females may not experience the same benefits from this combination treatment.
However, it's worth noting that the relative mass of the right ventricle did not show significant differences across all treatment groups. This suggests that while ubiquinol can be beneficial, particularly in males, the overall benefits may be limited and not as pronounced in females. Magnetic resonance imaging further revealed impaired lung perfusion in most rats tested, with signs of pulmonary fibrosis only present in the group receiving ubiquinol.
Overall, while ubiquinol shows potential in addressing pulmonary hypertension, its effectiveness might vary based on sex and should be approached with cautious optimism.
The results were quite enlightening. We observed that ubiquinol administered intravenously had a protective effect, especially in male rats. This treatment reduced the right ventricle hypertrophy and lung mass commonly associated with elevated blood pressure in the lungs. Interestingly, when we combined ubiquinol with selenium, we found a less severe increase in right ventricle systolic pressure in males but not in females, indicating a sex-dependent effect that suggests females may not experience the same benefits from this combination treatment.
However, it's worth noting that the relative mass of the right ventricle did not show significant differences across all treatment groups. This suggests that while ubiquinol can be beneficial, particularly in males, the overall benefits may be limited and not as pronounced in females. Magnetic resonance imaging further revealed impaired lung perfusion in most rats tested, with signs of pulmonary fibrosis only present in the group receiving ubiquinol.
Overall, while ubiquinol shows potential in addressing pulmonary hypertension, its effectiveness might vary based on sex and should be approached with cautious optimism.
Read More
Most Useful Reviews
9
Highly effective
1 people found this helpful
Excellent quality and dosage. I highly recommend it for managing hypertension, especially in conjunction with PQQ.
Read More
7.5
Helped my mother
Great ubiquinol! For me, ubiquinol from Now Foods 100 mg is a solid plus! It's Kaneka's brand, renowned for its quality. The capsules are easy to swallow, taken just once a day, and the benefits are considerable! As we age, our body’s production of ubiquinol diminishes, so it’s vital for those around 35 years, particularly for individuals with heart conditions, especially during stressful times. Ubiquinol is crucial for people on statins as it enhances the activity of various bodily enzymes and is also used to prevent diabetes, asthma, thyroid issues, and cancer. Personally, this Now Foods ubiquinol has significantly assisted my mother with her hypertension and palpitations. I advise taking it with a fat-containing meal.
Read More
6
Improves well-being
5 people found this helpful
For older individuals, this is a must! I regularly purchase it for my mum, who suffers from heart problems and hypertension. Ubiquinol boosts her energy and well-being. I usually buy 100 mg or alternate with 50 mg. It's a bit pricey, but my dad couldn’t take it — his blood pressure tends to be low, and ubiquinol made it drop even further. Thus, I opt for standard coenzymes for him.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 1 Research
7
- All Researches
7
Ubiquinol shows partial benefits
We explored the impact of ubiquinol on pulmonary hypertension using a model that mimics this serious condition. In our study, rats were injected with monocrotaline, a substance known to induce pulmonary hypertension. Over the course of the experiment, we provided various groups of these rats with different treatments, including solubilized ubiquinol and selenium, to see how these substances could protect against the effects of the disease.
The results were quite enlightening. We observed that ubiquinol administered intravenously had a protective effect, especially in male rats. This treatment reduced the right ventricle hypertrophy and lung mass commonly associated with elevated blood pressure in the lungs. Interestingly, when we combined ubiquinol with selenium, we found a less severe increase in right ventricle systolic pressure in males but not in females, indicating a sex-dependent effect that suggests females may not experience the same benefits from this combination treatment.
However, it's worth noting that the relative mass of the right ventricle did not show significant differences across all treatment groups. This suggests that while ubiquinol can be beneficial, particularly in males, the overall benefits may be limited and not as pronounced in females. Magnetic resonance imaging further revealed impaired lung perfusion in most rats tested, with signs of pulmonary fibrosis only present in the group receiving ubiquinol.
Overall, while ubiquinol shows potential in addressing pulmonary hypertension, its effectiveness might vary based on sex and should be approached with cautious optimism.
The results were quite enlightening. We observed that ubiquinol administered intravenously had a protective effect, especially in male rats. This treatment reduced the right ventricle hypertrophy and lung mass commonly associated with elevated blood pressure in the lungs. Interestingly, when we combined ubiquinol with selenium, we found a less severe increase in right ventricle systolic pressure in males but not in females, indicating a sex-dependent effect that suggests females may not experience the same benefits from this combination treatment.
However, it's worth noting that the relative mass of the right ventricle did not show significant differences across all treatment groups. This suggests that while ubiquinol can be beneficial, particularly in males, the overall benefits may be limited and not as pronounced in females. Magnetic resonance imaging further revealed impaired lung perfusion in most rats tested, with signs of pulmonary fibrosis only present in the group receiving ubiquinol.
Overall, while ubiquinol shows potential in addressing pulmonary hypertension, its effectiveness might vary based on sex and should be approached with cautious optimism.
Read More
User Reviews
USERS' SCORE
Good
Based on 4 Reviews
8.2
- All Reviews
- Positive Reviews
- Negative Reviews
9
Highly effective
1 people found this helpful
Excellent quality and dosage. I highly recommend it for managing hypertension, especially in conjunction with PQQ.
Read More
7.5
Helped my mother
Great ubiquinol! For me, ubiquinol from Now Foods 100 mg is a solid plus! It's Kaneka's brand, renowned for its quality. The capsules are easy to swallow, taken just once a day, and the benefits are considerable! As we age, our body’s production of ubiquinol diminishes, so it’s vital for those around 35 years, particularly for individuals with heart conditions, especially during stressful times. Ubiquinol is crucial for people on statins as it enhances the activity of various bodily enzymes and is also used to prevent diabetes, asthma, thyroid issues, and cancer. Personally, this Now Foods ubiquinol has significantly assisted my mother with her hypertension and palpitations. I advise taking it with a fat-containing meal.
Read More
6
Improves well-being
5 people found this helpful
For older individuals, this is a must! I regularly purchase it for my mum, who suffers from heart problems and hypertension. Ubiquinol boosts her energy and well-being. I usually buy 100 mg or alternate with 50 mg. It's a bit pricey, but my dad couldn’t take it — his blood pressure tends to be low, and ubiquinol made it drop even further. Thus, I opt for standard coenzymes for him.
Read More
7.5
Satisfied with results
Good product. It effectively helped manage my hypertension. I am satisfied.
Read More
Frequently Asked Questions
7.5
Helped my mother
Great ubiquinol! For me, ubiquinol from Now Foods 100 mg is a solid plus! It's Kaneka's brand, renowned for its quality. The capsules are easy to swallow, taken just once a day, and the benefits are considerable! As we age, our body’s production of ubiquinol diminishes, so it’s vital for those around 35 years, particularly for individuals with heart conditions, especially during stressful times. Ubiquinol is crucial for people on statins as it enhances the activity of various bodily enzymes and is also used to prevent diabetes, asthma, thyroid issues, and cancer. Personally, this Now Foods ubiquinol has significantly assisted my mother with her hypertension and palpitations. I advise taking it with a fat-containing meal.
7.5
Satisfied with results
Good product. It effectively helped manage my hypertension. I am satisfied.
6
Improves well-being
5 people found this helpful
For older individuals, this is a must! I regularly purchase it for my mum, who suffers from heart problems and hypertension. Ubiquinol boosts her energy and well-being. I usually buy 100 mg or alternate with 50 mg. It's a bit pricey, but my dad couldn’t take it — his blood pressure tends to be low, and ubiquinol made it drop even further. Thus, I opt for standard coenzymes for him.
9
Highly effective
1 people found this helpful
Excellent quality and dosage. I highly recommend it for managing hypertension, especially in conjunction with PQQ.
7
Ubiquinol shows partial benefits
We explored the impact of ubiquinol on pulmonary hypertension using a model that mimics this serious condition. In our study, rats were injected with monocrotaline, a substance known to induce pulmonary hypertension. Over the course of the experiment, we provided various groups of these rats with different treatments, including solubilized ubiquinol and selenium, to see how these substances could protect against the effects of the disease.
The results were quite enlightening. We observed that ubiquinol administered intravenously had a protective effect, especially in male rats. This treatment reduced the right ventricle hypertrophy and lung mass commonly associated with elevated blood pressure in the lungs. Interestingly, when we combined ubiquinol with selenium, we found a less severe increase in right ventricle systolic pressure in males but not in females, indicating a sex-dependent effect that suggests females may not experience the same benefits from this combination treatment.
However, it's worth noting that the relative mass of the right ventricle did not show significant differences across all treatment groups. This suggests that while ubiquinol can be beneficial, particularly in males, the overall benefits may be limited and not as pronounced in females. Magnetic resonance imaging further revealed impaired lung perfusion in most rats tested, with signs of pulmonary fibrosis only present in the group receiving ubiquinol.
Overall, while ubiquinol shows potential in addressing pulmonary hypertension, its effectiveness might vary based on sex and should be approached with cautious optimism.
The results were quite enlightening. We observed that ubiquinol administered intravenously had a protective effect, especially in male rats. This treatment reduced the right ventricle hypertrophy and lung mass commonly associated with elevated blood pressure in the lungs. Interestingly, when we combined ubiquinol with selenium, we found a less severe increase in right ventricle systolic pressure in males but not in females, indicating a sex-dependent effect that suggests females may not experience the same benefits from this combination treatment.
However, it's worth noting that the relative mass of the right ventricle did not show significant differences across all treatment groups. This suggests that while ubiquinol can be beneficial, particularly in males, the overall benefits may be limited and not as pronounced in females. Magnetic resonance imaging further revealed impaired lung perfusion in most rats tested, with signs of pulmonary fibrosis only present in the group receiving ubiquinol.
Overall, while ubiquinol shows potential in addressing pulmonary hypertension, its effectiveness might vary based on sex and should be approached with cautious optimism.
References
- Kuropatkina T, Pavlova O, Gulyaev M, Pirogov Y, Khutorova A, et al. Sex-Dependent Protective Effect of Combined Application of Solubilized Ubiquinol and Selenium on Monocrotaline-Induced Pulmonary Hypertension in Wistar Rats. Antioxidants (Basel). 2022;11. doi:10.3390/antiox11030549
