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SCIENTIFIC SCORE
Questionable
Based on 9 Researches
6.7
USERS' SCORE
Good
Based on 3 Reviews
8.6
Supplement Facts
Serving Size: 1 Softgel
Amount Per Serving
%DV
Vitamin D3 (as Cholecalciferol) (From Lanolin)
1,250 mcg (50,000 IU)
6250%
Top Medical Research Studies
9
Vitamin D3 reduces thyroid autoimmunity
A Prospective Study to Evaluate the Possible Role of Cholecalciferol Supplementation on Autoimmunity in Hashimoto's Thyroiditis.
Directly relates to hypothyroidism treatment
We explored the potential effects of vitamin D3, or cholecalciferol, on individuals diagnosed with Hashimoto's thyroiditis, a common form of hypothyroidism characterized by autoimmune responses that damage thyroid cells. Our study was a carefully structured clinical trial conducted over one year, which included 100 patients suffering from both Hashimoto's thyroiditis and vitamin D deficiency.
Divided into two groups, one received vitamin D3 supplements while the other was given a placebo. After eight weeks, we measured the levels of anti-thyroid peroxidase antibodies, which indicate autoimmune activity against the thyroid.
Our findings revealed a significant reduction in these antibody levels among patients who received vitamin D3, showcasing a 30.5% decrease compared to just a 16.5% decrease in the placebo group. This suggests that vitamin D3 supplementation may play a beneficial role in managing the autoimmune activity associated with hypothyroidism.
Overall, our research shows that addressing vitamin D deficiency might be an effective strategy to help manage Hashimoto's thyroiditis, which could encourage discussion about incorporating vitamin D as part of treatment plans for patients. Further research will be necessary to confirm these findings and explore the long-term benefits of vitamin D supplementation.
Divided into two groups, one received vitamin D3 supplements while the other was given a placebo. After eight weeks, we measured the levels of anti-thyroid peroxidase antibodies, which indicate autoimmune activity against the thyroid.
Our findings revealed a significant reduction in these antibody levels among patients who received vitamin D3, showcasing a 30.5% decrease compared to just a 16.5% decrease in the placebo group. This suggests that vitamin D3 supplementation may play a beneficial role in managing the autoimmune activity associated with hypothyroidism.
Overall, our research shows that addressing vitamin D deficiency might be an effective strategy to help manage Hashimoto's thyroiditis, which could encourage discussion about incorporating vitamin D as part of treatment plans for patients. Further research will be necessary to confirm these findings and explore the long-term benefits of vitamin D supplementation.
Read More
8
Vitamin D3 improves thyroid function
Effects of vitamin D supplementation on autoantibodies and thyroid function in patients with Hashimoto's thyroiditis: A systematic review and meta-analysis.
High relevance to hypothyroidism
We evaluated the effects of vitamin D3 supplementation on hypothyroidism, specifically in patients with Hashimoto's thyroiditis (HT). Our analysis involved 12 randomized controlled trials, comparing the outcomes of individuals receiving vitamin D3 against those given a placebo or no treatment at all.
Through this thorough examination, we found that vitamin D3 did promote significant improvements in thyroid function and immune response. Specifically, we observed a reduction in two key antibodies: anti-thyroid peroxidase (TPO-Ab) and thyroglobulin antibody (TG-Ab). These reductions suggest a positive effect on the autoimmune process involved in Hashimoto's thyroiditis.
Additionally, we noted improvements in thyroid hormone levels, including free thyroxine (FT4) and free triiodothyronine (FT3), while thyroid-stimulating hormone (TSH) levels showed a decrease. These findings indicate that vitamin D3 supplementation may benefit thyroid health and help manage hypothyroidism more effectively.
For those considering vitamin D3 as a treatment option, particularly those who have been on vitamin D for longer than 12 weeks, the results suggest a more pronounced effect on improving antibody levels and thyroid function. Thus, there appears to be a compelling case for vitamin D3 as a supportive treatment in managing Hashimoto's thyroiditis and related hypothyroidism.
Through this thorough examination, we found that vitamin D3 did promote significant improvements in thyroid function and immune response. Specifically, we observed a reduction in two key antibodies: anti-thyroid peroxidase (TPO-Ab) and thyroglobulin antibody (TG-Ab). These reductions suggest a positive effect on the autoimmune process involved in Hashimoto's thyroiditis.
Additionally, we noted improvements in thyroid hormone levels, including free thyroxine (FT4) and free triiodothyronine (FT3), while thyroid-stimulating hormone (TSH) levels showed a decrease. These findings indicate that vitamin D3 supplementation may benefit thyroid health and help manage hypothyroidism more effectively.
For those considering vitamin D3 as a treatment option, particularly those who have been on vitamin D for longer than 12 weeks, the results suggest a more pronounced effect on improving antibody levels and thyroid function. Thus, there appears to be a compelling case for vitamin D3 as a supportive treatment in managing Hashimoto's thyroiditis and related hypothyroidism.
Read More
8
Vitamin D3 impacts thyroid health
Vitamin D Treatment in Patients with Hashimoto's Thyroiditis may Decrease the Development of Hypothyroidism.
Significant relevance to Hashimoto's
We evaluated the potential impact of vitamin D3 treatment on patients suffering from Hashimoto's thyroiditis, particularly looking at its effect on the development of hypothyroidism. Our investigation included 75 individuals diagnosed with this autoimmune disorder and a control group of 43 healthy participants. The results showed that patients with Hashimoto's thyroiditis had notably lower vitamin D levels compared to those without the condition.
To address vitamin D deficiency, we administered a weekly dose of 50,000 units of vitamin D3 to those who were lacking it for eight weeks. After this treatment, we observed significant improvements. Thyroid autoantibodies, which indicate inflammation and damage in the thyroid, decreased in those who were treated. Additionally, we found that levels of HDL cholesterol improved, suggesting potential benefits for cardiovascular health.
Our findings point toward vitamin D deficiency being common among those with Hashimoto's thyroiditis. By addressing this deficiency, we may slow down the progression toward hypothyroidism and reduce cardiovascular risks associated with the condition. Therefore, monitoring and supplementing vitamin D could play a crucial role in managing the health of these patients effectively.
To address vitamin D deficiency, we administered a weekly dose of 50,000 units of vitamin D3 to those who were lacking it for eight weeks. After this treatment, we observed significant improvements. Thyroid autoantibodies, which indicate inflammation and damage in the thyroid, decreased in those who were treated. Additionally, we found that levels of HDL cholesterol improved, suggesting potential benefits for cardiovascular health.
Our findings point toward vitamin D deficiency being common among those with Hashimoto's thyroiditis. By addressing this deficiency, we may slow down the progression toward hypothyroidism and reduce cardiovascular risks associated with the condition. Therefore, monitoring and supplementing vitamin D could play a crucial role in managing the health of these patients effectively.
Read More
Most Useful Reviews
9.5
Improved symptoms
An excellent supplement for addressing deficiencies; it has greatly improved my symptoms related to Hashimoto's hypothyroidism. The quality is good, with proper absorption, and it's flavourless. Overall, I have noticed many benefits.
Read More
8.8
Vitamin D3 dosage
My aunt has hypothyroidism. The doctor advised her to take this dosage of vitamin D3 as she was found to be deficient.
Read More
8.8
Convenient dosage
This high-dose vitamin D from a trusted brand is convenient as it's taken once a week, and it assists in managing my hypothyroidism effectively.
Read More
Medical Researches
SCIENTIFIC SCORE
Questionable
Based on 9 Researches
6.7
9
Vitamin D3 reduces thyroid autoimmunity
A Prospective Study to Evaluate the Possible Role of Cholecalciferol Supplementation on Autoimmunity in Hashimoto's Thyroiditis.
Directly relates to hypothyroidism treatment
We explored the potential effects of vitamin D3, or cholecalciferol, on individuals diagnosed with Hashimoto's thyroiditis, a common form of hypothyroidism characterized by autoimmune responses that damage thyroid cells. Our study was a carefully structured clinical trial conducted over one year, which included 100 patients suffering from both Hashimoto's thyroiditis and vitamin D deficiency.
Divided into two groups, one received vitamin D3 supplements while the other was given a placebo. After eight weeks, we measured the levels of anti-thyroid peroxidase antibodies, which indicate autoimmune activity against the thyroid.
Our findings revealed a significant reduction in these antibody levels among patients who received vitamin D3, showcasing a 30.5% decrease compared to just a 16.5% decrease in the placebo group. This suggests that vitamin D3 supplementation may play a beneficial role in managing the autoimmune activity associated with hypothyroidism.
Overall, our research shows that addressing vitamin D deficiency might be an effective strategy to help manage Hashimoto's thyroiditis, which could encourage discussion about incorporating vitamin D as part of treatment plans for patients. Further research will be necessary to confirm these findings and explore the long-term benefits of vitamin D supplementation.
Divided into two groups, one received vitamin D3 supplements while the other was given a placebo. After eight weeks, we measured the levels of anti-thyroid peroxidase antibodies, which indicate autoimmune activity against the thyroid.
Our findings revealed a significant reduction in these antibody levels among patients who received vitamin D3, showcasing a 30.5% decrease compared to just a 16.5% decrease in the placebo group. This suggests that vitamin D3 supplementation may play a beneficial role in managing the autoimmune activity associated with hypothyroidism.
Overall, our research shows that addressing vitamin D deficiency might be an effective strategy to help manage Hashimoto's thyroiditis, which could encourage discussion about incorporating vitamin D as part of treatment plans for patients. Further research will be necessary to confirm these findings and explore the long-term benefits of vitamin D supplementation.
Read More
9
Vitamin D3 and iodine benefits
Increased Epoxyeicosatrienoic Acids and Hydroxyeicosatetraenoic Acids After Treatment of Iodide Intake Adjustment and 1,25-Dihydroxy-Vitamin D Supplementation in High Iodide Intake-Induced Hypothyroid Offspring Rats.
Vitamin D3 effect remains unclear
We investigated the potential benefits of vitamin D3 in treating hypothyroidism caused by high iodide intake in a study involving pregnant rats. The study involved adjusting iodide intake and supplementing with 1,25-dihydroxy-vitamin D (the active form of vitamin D) to see if these interventions could positively impact thyroid function and related complications.
The newborn rats were exposed to high levels of iodide initially, leading to thyroid dysfunction. After some weeks, we provided either iodide adjustment, vitamin D3 supplementation, or both to assess their effects.
Surprisingly, while vitamin D3 was combined with iodide adjustment, the study did not isolate the effect of vitamin D3 alone. However, we observed that both interventions increased levels of beneficial fatty acids, which are linked to improved thyroid function and lessened cholesterol issues in these rats.
These results suggest that implementing a proper iodide intake and vitamin D3 supplementation can improve thyroid health but do not clearly define vitamin D3's individual impact without additional research isolating its effects.
The newborn rats were exposed to high levels of iodide initially, leading to thyroid dysfunction. After some weeks, we provided either iodide adjustment, vitamin D3 supplementation, or both to assess their effects.
Surprisingly, while vitamin D3 was combined with iodide adjustment, the study did not isolate the effect of vitamin D3 alone. However, we observed that both interventions increased levels of beneficial fatty acids, which are linked to improved thyroid function and lessened cholesterol issues in these rats.
These results suggest that implementing a proper iodide intake and vitamin D3 supplementation can improve thyroid health but do not clearly define vitamin D3's individual impact without additional research isolating its effects.
Read More
8
Vitamin D3 improves thyroid function
Effects of vitamin D supplementation on autoantibodies and thyroid function in patients with Hashimoto's thyroiditis: A systematic review and meta-analysis.
High relevance to hypothyroidism
We evaluated the effects of vitamin D3 supplementation on hypothyroidism, specifically in patients with Hashimoto's thyroiditis (HT). Our analysis involved 12 randomized controlled trials, comparing the outcomes of individuals receiving vitamin D3 against those given a placebo or no treatment at all.
Through this thorough examination, we found that vitamin D3 did promote significant improvements in thyroid function and immune response. Specifically, we observed a reduction in two key antibodies: anti-thyroid peroxidase (TPO-Ab) and thyroglobulin antibody (TG-Ab). These reductions suggest a positive effect on the autoimmune process involved in Hashimoto's thyroiditis.
Additionally, we noted improvements in thyroid hormone levels, including free thyroxine (FT4) and free triiodothyronine (FT3), while thyroid-stimulating hormone (TSH) levels showed a decrease. These findings indicate that vitamin D3 supplementation may benefit thyroid health and help manage hypothyroidism more effectively.
For those considering vitamin D3 as a treatment option, particularly those who have been on vitamin D for longer than 12 weeks, the results suggest a more pronounced effect on improving antibody levels and thyroid function. Thus, there appears to be a compelling case for vitamin D3 as a supportive treatment in managing Hashimoto's thyroiditis and related hypothyroidism.
Through this thorough examination, we found that vitamin D3 did promote significant improvements in thyroid function and immune response. Specifically, we observed a reduction in two key antibodies: anti-thyroid peroxidase (TPO-Ab) and thyroglobulin antibody (TG-Ab). These reductions suggest a positive effect on the autoimmune process involved in Hashimoto's thyroiditis.
Additionally, we noted improvements in thyroid hormone levels, including free thyroxine (FT4) and free triiodothyronine (FT3), while thyroid-stimulating hormone (TSH) levels showed a decrease. These findings indicate that vitamin D3 supplementation may benefit thyroid health and help manage hypothyroidism more effectively.
For those considering vitamin D3 as a treatment option, particularly those who have been on vitamin D for longer than 12 weeks, the results suggest a more pronounced effect on improving antibody levels and thyroid function. Thus, there appears to be a compelling case for vitamin D3 as a supportive treatment in managing Hashimoto's thyroiditis and related hypothyroidism.
Read More
8
Vitamin D3 impacts thyroid health
Vitamin D Treatment in Patients with Hashimoto's Thyroiditis may Decrease the Development of Hypothyroidism.
Significant relevance to Hashimoto's
We evaluated the potential impact of vitamin D3 treatment on patients suffering from Hashimoto's thyroiditis, particularly looking at its effect on the development of hypothyroidism. Our investigation included 75 individuals diagnosed with this autoimmune disorder and a control group of 43 healthy participants. The results showed that patients with Hashimoto's thyroiditis had notably lower vitamin D levels compared to those without the condition.
To address vitamin D deficiency, we administered a weekly dose of 50,000 units of vitamin D3 to those who were lacking it for eight weeks. After this treatment, we observed significant improvements. Thyroid autoantibodies, which indicate inflammation and damage in the thyroid, decreased in those who were treated. Additionally, we found that levels of HDL cholesterol improved, suggesting potential benefits for cardiovascular health.
Our findings point toward vitamin D deficiency being common among those with Hashimoto's thyroiditis. By addressing this deficiency, we may slow down the progression toward hypothyroidism and reduce cardiovascular risks associated with the condition. Therefore, monitoring and supplementing vitamin D could play a crucial role in managing the health of these patients effectively.
To address vitamin D deficiency, we administered a weekly dose of 50,000 units of vitamin D3 to those who were lacking it for eight weeks. After this treatment, we observed significant improvements. Thyroid autoantibodies, which indicate inflammation and damage in the thyroid, decreased in those who were treated. Additionally, we found that levels of HDL cholesterol improved, suggesting potential benefits for cardiovascular health.
Our findings point toward vitamin D deficiency being common among those with Hashimoto's thyroiditis. By addressing this deficiency, we may slow down the progression toward hypothyroidism and reduce cardiovascular risks associated with the condition. Therefore, monitoring and supplementing vitamin D could play a crucial role in managing the health of these patients effectively.
Read More
8
Vitamin D3 may reduce HT risk
The association between serum 25OHD levels and hypothyroid Hashimoto's thyroiditis.
Moderate relevance for treatment evaluation
We set out to understand the relationship between vitamin D3 levels and hypothyroid Hashimoto's thyroiditis (HT), a common autoimmune condition. During our investigation, we enrolled 86 participants, dividing them into two groups: 41 patients suffering from hypothyroid HT and 45 healthy individuals with normal thyroid function.
Our findings revealed an interesting trend. We observed that lower serum levels of 25-hydroxyvitamin D (25OHD) were significantly associated with HT. Specifically, for every increase of 5 ng/ml in 25OHD, the odds of developing HT decreased by approximately 19%. This pattern persisted even after we factored in variables such as age, gender, and body mass index (BMI).
Overall, higher levels of vitamin D3 appear to correlate with a reduced risk of HT. This suggests that maintaining adequate vitamin D3 levels could play a beneficial role in preventing or managing this autoimmune condition. However, while our study shows a clear association, it does not isolate the effects of vitamin D3 from other factors that may also influence thyroid health.
Our findings revealed an interesting trend. We observed that lower serum levels of 25-hydroxyvitamin D (25OHD) were significantly associated with HT. Specifically, for every increase of 5 ng/ml in 25OHD, the odds of developing HT decreased by approximately 19%. This pattern persisted even after we factored in variables such as age, gender, and body mass index (BMI).
Overall, higher levels of vitamin D3 appear to correlate with a reduced risk of HT. This suggests that maintaining adequate vitamin D3 levels could play a beneficial role in preventing or managing this autoimmune condition. However, while our study shows a clear association, it does not isolate the effects of vitamin D3 from other factors that may also influence thyroid health.
Read More
User Reviews
USERS' SCORE
Good
Based on 3 Reviews
8.6
9.5
Improved symptoms
An excellent supplement for addressing deficiencies; it has greatly improved my symptoms related to Hashimoto's hypothyroidism. The quality is good, with proper absorption, and it's flavourless. Overall, I have noticed many benefits.
8.8
Vitamin D3 dosage
My aunt has hypothyroidism. The doctor advised her to take this dosage of vitamin D3 as she was found to be deficient.
8.8
Convenient dosage
This high-dose vitamin D from a trusted brand is convenient as it's taken once a week, and it assists in managing my hypothyroidism effectively.
