Last update
5/15/2026
Reviewed By
Overview
SCIENTIFIC SCORE
Moderately Effective
Based on 1 Research
8
USERS' SCORE
Medium or Average
Based on 12 Reviews
6.6
Supplement Facts
Serving Size: 1 Veg Capsule
Amount Per Serving
%DV
Vitamin C (as Ascorbic Acid)
1 g (1,000 mg)
1111%
Citrus Bioflavonoid Complex
100 mg
†
Rutin Powder (from Sophora japonica Flower Bud)
25 mg
†
Top Medical Research Studies
8
Vitamin C reduces heartburn symptoms
We investigated how vitamin C, specifically in the form of a 2% vitamin C solution spray, could help alleviate heartburn symptoms following Lugol chromoendoscopy, a procedure that involves staining the esophagus to better visualize abnormalities. In a well-structured study with 240 participants, we used a randomized, double-blind approach to compare the effectiveness of vitamin C to normal saline and sodium thiosulfate solutions.
Our results showed that vitamin C spray significantly reduced both acute heartburn symptoms and late discomfort when compared to the saline solution. Specifically, 33% of participants using vitamin C reported relief from acid regurgitation or heartburn, compared to just 15% with sodium thiosulfate. Additionally, patients noted an improvement in retrosternal pain, with 21% finding relief from the vitamin C treatment versus 9% from sodium thiosulfate.
Furthermore, vitamin C offered a quicker discoloration of the iodine-stained mucosa compared to saline, enhancing the overall experience of the procedure. These findings suggest that incorporating vitamin C spray into post-procedural care could be a helpful strategy for patients facing discomfort after undergoing Lugol chromoendoscopy.
Our results showed that vitamin C spray significantly reduced both acute heartburn symptoms and late discomfort when compared to the saline solution. Specifically, 33% of participants using vitamin C reported relief from acid regurgitation or heartburn, compared to just 15% with sodium thiosulfate. Additionally, patients noted an improvement in retrosternal pain, with 21% finding relief from the vitamin C treatment versus 9% from sodium thiosulfate.
Furthermore, vitamin C offered a quicker discoloration of the iodine-stained mucosa compared to saline, enhancing the overall experience of the procedure. These findings suggest that incorporating vitamin C spray into post-procedural care could be a helpful strategy for patients facing discomfort after undergoing Lugol chromoendoscopy.
Read More
Most Useful Reviews
0
Caused severe heartburn
4 people found this helpful
Unfortunately, this product caused severe heartburn for me, which I had never experienced before. Despite several attempts to take it, the result was always the same. My mother, however, had no issues with it.
Read More
10
Effective heartburn treatment
1 people found this helpful
I switched from regular vitamin C due to heartburn issues. With this product, I experience no heartburn, even with two tablets. The price is great, and I love the Now brand.
Read More
9
Heartburn-free vitamin
1 people found this helpful
I added this vitamin to my diet to bolster my immunity. I have not experienced any heartburn or runny nose while taking it. I'm satisfied with the product and will continue using it.
Read More
Medical Researches
SCIENTIFIC SCORE
Moderately Effective
Based on 1 Research
8
- All Researches
8
Vitamin C reduces heartburn symptoms
We investigated how vitamin C, specifically in the form of a 2% vitamin C solution spray, could help alleviate heartburn symptoms following Lugol chromoendoscopy, a procedure that involves staining the esophagus to better visualize abnormalities. In a well-structured study with 240 participants, we used a randomized, double-blind approach to compare the effectiveness of vitamin C to normal saline and sodium thiosulfate solutions.
Our results showed that vitamin C spray significantly reduced both acute heartburn symptoms and late discomfort when compared to the saline solution. Specifically, 33% of participants using vitamin C reported relief from acid regurgitation or heartburn, compared to just 15% with sodium thiosulfate. Additionally, patients noted an improvement in retrosternal pain, with 21% finding relief from the vitamin C treatment versus 9% from sodium thiosulfate.
Furthermore, vitamin C offered a quicker discoloration of the iodine-stained mucosa compared to saline, enhancing the overall experience of the procedure. These findings suggest that incorporating vitamin C spray into post-procedural care could be a helpful strategy for patients facing discomfort after undergoing Lugol chromoendoscopy.
Our results showed that vitamin C spray significantly reduced both acute heartburn symptoms and late discomfort when compared to the saline solution. Specifically, 33% of participants using vitamin C reported relief from acid regurgitation or heartburn, compared to just 15% with sodium thiosulfate. Additionally, patients noted an improvement in retrosternal pain, with 21% finding relief from the vitamin C treatment versus 9% from sodium thiosulfate.
Furthermore, vitamin C offered a quicker discoloration of the iodine-stained mucosa compared to saline, enhancing the overall experience of the procedure. These findings suggest that incorporating vitamin C spray into post-procedural care could be a helpful strategy for patients facing discomfort after undergoing Lugol chromoendoscopy.
Read More
User Reviews
USERS' SCORE
Medium or Average
Based on 12 Reviews
6.6
- All Reviews
- Positive Reviews
- Negative Reviews
0
Caused severe heartburn
4 people found this helpful
Unfortunately, this product caused severe heartburn for me, which I had never experienced before. Despite several attempts to take it, the result was always the same. My mother, however, had no issues with it.
Read More
10
Effective heartburn treatment
1 people found this helpful
I switched from regular vitamin C due to heartburn issues. With this product, I experience no heartburn, even with two tablets. The price is great, and I love the Now brand.
Read More
9
Heartburn-free vitamin
1 people found this helpful
I added this vitamin to my diet to bolster my immunity. I have not experienced any heartburn or runny nose while taking it. I'm satisfied with the product and will continue using it.
Read More
9
Effective alternative
1 people found this helpful
I opted for this vitamin C to save on costs compared to Solgar, which is twice the price. I anticipated heartburn, but thankfully, I didn't experience it! The product is excellent and effective; we barely bought oranges last winter as I didn’t want to rely on fruits lacking in vitamins. At the first sign of illness, I take 500 mg three times a day. Typically, by morning, I'm symptom-free. I will order it again multiple times.
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0
Causes heartburn
1 people found this helpful
Although the composition seemed good and the reviews were positive, it caused me belching and heartburn.
Read More
Frequently Asked Questions
9
Effective alternative
1 people found this helpful
I opted for this vitamin C to save on costs compared to Solgar, which is twice the price. I anticipated heartburn, but thankfully, I didn't experience it! The product is excellent and effective; we barely bought oranges last winter as I didn’t want to rely on fruits lacking in vitamins. At the first sign of illness, I take 500 mg three times a day. Typically, by morning, I'm symptom-free. I will order it again multiple times.
0
Caused severe heartburn
4 people found this helpful
Unfortunately, this product caused severe heartburn for me, which I had never experienced before. Despite several attempts to take it, the result was always the same. My mother, however, had no issues with it.
4
Occasional heartburn
1 people found this helpful
After taking it, I sometimes experienced heartburn, likely due to increased acidity. I didn't have this issue with Ester-S.
8
Vitamin C reduces heartburn symptoms
We investigated how vitamin C, specifically in the form of a 2% vitamin C solution spray, could help alleviate heartburn symptoms following Lugol chromoendoscopy, a procedure that involves staining the esophagus to better visualize abnormalities. In a well-structured study with 240 participants, we used a randomized, double-blind approach to compare the effectiveness of vitamin C to normal saline and sodium thiosulfate solutions.
Our results showed that vitamin C spray significantly reduced both acute heartburn symptoms and late discomfort when compared to the saline solution. Specifically, 33% of participants using vitamin C reported relief from acid regurgitation or heartburn, compared to just 15% with sodium thiosulfate. Additionally, patients noted an improvement in retrosternal pain, with 21% finding relief from the vitamin C treatment versus 9% from sodium thiosulfate.
Furthermore, vitamin C offered a quicker discoloration of the iodine-stained mucosa compared to saline, enhancing the overall experience of the procedure. These findings suggest that incorporating vitamin C spray into post-procedural care could be a helpful strategy for patients facing discomfort after undergoing Lugol chromoendoscopy.
Our results showed that vitamin C spray significantly reduced both acute heartburn symptoms and late discomfort when compared to the saline solution. Specifically, 33% of participants using vitamin C reported relief from acid regurgitation or heartburn, compared to just 15% with sodium thiosulfate. Additionally, patients noted an improvement in retrosternal pain, with 21% finding relief from the vitamin C treatment versus 9% from sodium thiosulfate.
Furthermore, vitamin C offered a quicker discoloration of the iodine-stained mucosa compared to saline, enhancing the overall experience of the procedure. These findings suggest that incorporating vitamin C spray into post-procedural care could be a helpful strategy for patients facing discomfort after undergoing Lugol chromoendoscopy.
References
- Jin D, Wang J, Zhan Q, Huang K, Wang H, et al. The safety and efficacy of 2% vitamin C solution spray for relief of mucosal irritation caused by Lugol chromoendoscopy: a multicenter, randomized, double-blind, parallel trial. Gastrointest Endosc. 2020;92:554. 10.1016/j.gie.2019.11.028
