SCIENTIFIC SCORE
Possibly Effective
Based on 2 Researches
7.5
USERS' SCORE
Good
Based on 6 Reviews
8.5
Supplement Facts
Serving Size: 1 Veg Capsule
Amount Per Serving
%DV
Vitamin C (as Ascorbic Acid)
1 g (1,000 mg)
1111%
Citrus Bioflavonoid Complex
100 mg
†
Rutin Powder (from Sophora japonica Flower Bud)
25 mg
†
Top Medical Research Studies
8
Vitamin C aids omeprazole therapy
Antioxidant pre-treatment prevents omeprazole-induced toxicity in an in vitro model of infectious gastritis.
Moderate relevance to reflux treatment
We aimed to understand how Vitamin C could help with the toxicity caused by omeprazole, a common treatment for conditions like gastroesophageal reflux disease (GERD) and gastritis. During our study, we examined gastric cells from rabbits to see how Vitamin C, alongside other antioxidants, could protect these cells from damage caused by omeprazole.
We found that both omeprazole and another thiol-oxidant, monochloramine, significantly reduced cell viability. Interestingly, the toxicity from omeprazole occurred independently from monochloramine. However, we observed that using Vitamin C effectively protected the gastric cells from this injury, maintaining their function without interfering with omeprazole's intended effects.
This suggests that incorporating Vitamin C into treatment plans for people using proton pump inhibitors (PPIs) like omeprazole could be beneficial. Ultimately, our research highlights the potential of using antioxidants to mitigate the adverse effects often associated with medication for reflux and related conditions.
We found that both omeprazole and another thiol-oxidant, monochloramine, significantly reduced cell viability. Interestingly, the toxicity from omeprazole occurred independently from monochloramine. However, we observed that using Vitamin C effectively protected the gastric cells from this injury, maintaining their function without interfering with omeprazole's intended effects.
This suggests that incorporating Vitamin C into treatment plans for people using proton pump inhibitors (PPIs) like omeprazole could be beneficial. Ultimately, our research highlights the potential of using antioxidants to mitigate the adverse effects often associated with medication for reflux and related conditions.
Read More
7
Antioxidants may reduce cancer risk
Dietary antioxidant and mineral intake in humans is associated with reduced risk of esophageal adenocarcinoma but not reflux esophagitis or Barrett's esophagus.
Limited isolation of vitamin C effects
We studied how antioxidants, particularly vitamin C, relate to reflux esophagitis and esophageal adenocarcinoma, aiming to uncover potential protective effects. Through a case-control approach involving groups with reflux esophagitis, Barrett's esophagus, and esophageal adenocarcinoma, we assessed the dietary intake of antioxidants and their relationship with these conditions.
Our findings revealed that a higher overall antioxidant intake was linked to a reduced risk of esophageal adenocarcinoma. Specifically, individuals with the highest vitamin C intake had a significantly lower risk of developing this type of cancer. However, while vitamin C also appeared to reduce the risk of reflux esophagitis, we found no strong connection between vitamin C and Barrett's esophagus, nor with other antioxidants such as vitamin E, carotenoids, zinc, copper, or selenium.
This suggests that while antioxidants could play a role in lowering the risk of esophageal adenocarcinoma, they might be more influential in terms of progression rather than initiating reflux conditions. Overall, our study highlights the potential significance of dietary vitamin C in addressing reflux issues but points out limitations when it comes to other forms of esophageal disorders.
Our findings revealed that a higher overall antioxidant intake was linked to a reduced risk of esophageal adenocarcinoma. Specifically, individuals with the highest vitamin C intake had a significantly lower risk of developing this type of cancer. However, while vitamin C also appeared to reduce the risk of reflux esophagitis, we found no strong connection between vitamin C and Barrett's esophagus, nor with other antioxidants such as vitamin E, carotenoids, zinc, copper, or selenium.
This suggests that while antioxidants could play a role in lowering the risk of esophageal adenocarcinoma, they might be more influential in terms of progression rather than initiating reflux conditions. Overall, our study highlights the potential significance of dietary vitamin C in addressing reflux issues but points out limitations when it comes to other forms of esophageal disorders.
Read More
Most Useful Reviews
10
No acidic reflux
This supplement contains a high dose, which is fantastic, and it doesn’t cause any acid reflux like some other vitamin C supplements do.
Read More
10
No reflux issues
A very good vitamin C with a big dose at a cheap price, and it does not cause reflux.
Read More
8.8
Relief from heartburn
My wife and I have tried a few other vitamin C brands that gave her terrible heartburn. We've been taking NOW vitamin C for some time now (on our second bottle), and she hasn't experienced any heartburn or acid reflux issues from it. The pills aren't tiny, but I find them easy to swallow. I can't recall when I last felt unwell, and I truly believe that taking vitamin C is the primary reason. I currently take two tablets daily (2,000 mg in total), one with breakfast and one with dinner. I usually increase to four when I've been around sick people.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 2 Researches
7.5
- All Researches
8
Vitamin C aids omeprazole therapy
Antioxidant pre-treatment prevents omeprazole-induced toxicity in an in vitro model of infectious gastritis.
Moderate relevance to reflux treatment
We aimed to understand how Vitamin C could help with the toxicity caused by omeprazole, a common treatment for conditions like gastroesophageal reflux disease (GERD) and gastritis. During our study, we examined gastric cells from rabbits to see how Vitamin C, alongside other antioxidants, could protect these cells from damage caused by omeprazole.
We found that both omeprazole and another thiol-oxidant, monochloramine, significantly reduced cell viability. Interestingly, the toxicity from omeprazole occurred independently from monochloramine. However, we observed that using Vitamin C effectively protected the gastric cells from this injury, maintaining their function without interfering with omeprazole's intended effects.
This suggests that incorporating Vitamin C into treatment plans for people using proton pump inhibitors (PPIs) like omeprazole could be beneficial. Ultimately, our research highlights the potential of using antioxidants to mitigate the adverse effects often associated with medication for reflux and related conditions.
We found that both omeprazole and another thiol-oxidant, monochloramine, significantly reduced cell viability. Interestingly, the toxicity from omeprazole occurred independently from monochloramine. However, we observed that using Vitamin C effectively protected the gastric cells from this injury, maintaining their function without interfering with omeprazole's intended effects.
This suggests that incorporating Vitamin C into treatment plans for people using proton pump inhibitors (PPIs) like omeprazole could be beneficial. Ultimately, our research highlights the potential of using antioxidants to mitigate the adverse effects often associated with medication for reflux and related conditions.
Read More
7
Antioxidants may reduce cancer risk
Dietary antioxidant and mineral intake in humans is associated with reduced risk of esophageal adenocarcinoma but not reflux esophagitis or Barrett's esophagus.
Limited isolation of vitamin C effects
We studied how antioxidants, particularly vitamin C, relate to reflux esophagitis and esophageal adenocarcinoma, aiming to uncover potential protective effects. Through a case-control approach involving groups with reflux esophagitis, Barrett's esophagus, and esophageal adenocarcinoma, we assessed the dietary intake of antioxidants and their relationship with these conditions.
Our findings revealed that a higher overall antioxidant intake was linked to a reduced risk of esophageal adenocarcinoma. Specifically, individuals with the highest vitamin C intake had a significantly lower risk of developing this type of cancer. However, while vitamin C also appeared to reduce the risk of reflux esophagitis, we found no strong connection between vitamin C and Barrett's esophagus, nor with other antioxidants such as vitamin E, carotenoids, zinc, copper, or selenium.
This suggests that while antioxidants could play a role in lowering the risk of esophageal adenocarcinoma, they might be more influential in terms of progression rather than initiating reflux conditions. Overall, our study highlights the potential significance of dietary vitamin C in addressing reflux issues but points out limitations when it comes to other forms of esophageal disorders.
Our findings revealed that a higher overall antioxidant intake was linked to a reduced risk of esophageal adenocarcinoma. Specifically, individuals with the highest vitamin C intake had a significantly lower risk of developing this type of cancer. However, while vitamin C also appeared to reduce the risk of reflux esophagitis, we found no strong connection between vitamin C and Barrett's esophagus, nor with other antioxidants such as vitamin E, carotenoids, zinc, copper, or selenium.
This suggests that while antioxidants could play a role in lowering the risk of esophageal adenocarcinoma, they might be more influential in terms of progression rather than initiating reflux conditions. Overall, our study highlights the potential significance of dietary vitamin C in addressing reflux issues but points out limitations when it comes to other forms of esophageal disorders.
Read More
User Reviews
USERS' SCORE
Good
Based on 6 Reviews
8.5
- All Reviews
- Positive Reviews
- Negative Reviews
10
No acidic reflux
This supplement contains a high dose, which is fantastic, and it doesn’t cause any acid reflux like some other vitamin C supplements do.
10
No reflux issues
A very good vitamin C with a big dose at a cheap price, and it does not cause reflux.
8.8
Relief from heartburn
My wife and I have tried a few other vitamin C brands that gave her terrible heartburn. We've been taking NOW vitamin C for some time now (on our second bottle), and she hasn't experienced any heartburn or acid reflux issues from it. The pills aren't tiny, but I find them easy to swallow. I can't recall when I last felt unwell, and I truly believe that taking vitamin C is the primary reason. I currently take two tablets daily (2,000 mg in total), one with breakfast and one with dinner. I usually increase to four when I've been around sick people.
Read More
8.8
Avoided acid reflux
This great product did not cause acid reflux, is reasonably priced, and easy to swallow.
6.3
Not ideal for reflux
Bad for reflux. Contains a citrus bioflavonoid complex (citrus = acidic). Yes, this product is "better" than standard ascorbic acid for reflux conditions, but it remains far from ideal.
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