Overview

SCIENTIFIC SCORE
Possibly Effective
Based on 4 Researches
7.8
USERS' SCORE
Good
Based on 5 Reviews
8.6
Supplement Facts
Serving Size: 1 Veg Capsule
Amount Per Serving
%DV
Thiamin (Vitamin B-1) (from Thiamin HCl)
50 mg
4167%
Riboflavin (Vitamin B-2)
50 mg
3846%
Niacin (Vitamin B-3) (as Niacinamide)
50 mg
313%
Vitamin B-6 (from Pyridoxine HCl)
50 mg
2941%
Folate
680 mcg DFE (400 mcg folic acid)
170%
Vitamin B-12 (as Cyanocobalamin)
50 mcg
2083%
Biotin
50 mcg
167%
Pantothenic Acid (from Calcium Pantothenate)
50 mg
1000%
Choline (from Choline Bitartrate)
25 mg
5%
PABA (Para-Aminobenzoic Acid)
25 mg
Inositol
25 mg

Top Medical Research Studies

9
Thiamine enhances memory in hypothyroidism
We explored the impact of thiamine (Vitamin B1) on memory and learning in rats with hypothyroidism. In a study involving 50 young rats, we treated them with a hypothyroid-inducing agent and varying doses of thiamine over seven weeks.

The results were promising—thiamine improved memory in rats as evidenced by better performance in timed tests. Specifically, higher doses of thiamine led to increased memory retention and reduced oxidative stress. This suggests that thiamine could be a beneficial supplement for addressing memory issues related to hypothyroidism.
Read More
8
Vitamin B benefits hypothyroidism treatment
We aimed to explore how B vitamins, including pyridoxine, betaine, folic acid, and cyanocobalamin, can correct homocysteine metabolism disrupted by hypothyroidism. By studying experimental rats treated for prolonged periods, we found that hypothyroidism severely reduced the activity of key enzymes involved in methylation, which in turn raised homocysteine levels—linked to heart disease risk.

Our findings indicate that B vitamins have a promising potential to lower these harmful homocysteine levels and could help prevent complications like endothelial dysfunction in hypothyroid patients.
Read More
7
Vitamin B12 deficiency linked to hypothyroidism
We explored the connection between vitamin B12 levels and hypothyroidism in a study involving 100 patients. A significant 68% of these patients were found to be vitamin B12 deficient, with a notable correlation to the presence of anti TPO and anti Thyroglobulin antibodies.

This suggests that vitamin B12 may play a role in the symptoms experienced by hypothyroid individuals, especially since thyroid hormones influence the production of red blood cells. While supplementation could potentially help alleviate these symptoms, further research is essential to confirm its effectiveness in routine treatment.
Read More

Most Useful Reviews

9
Increased energy levels
114 people found this helpful
I liked the B-complex! After my lunch, I took one capsule. Having hypothyroidism, I often felt fatigued, weak, and irritable. Following tests, I addressed my deficiencies in vitamin B and iron, as B vitamins aid iron absorption. NOW B-50 complex is well-balanced with B-1, B-2, B-3, B-6, B-12, Biotin, Choline, Inositol, and Pantothenic Acid. After the course, I experienced a surge of energy that lasted throughout the day!
Read More
7.5
Recommended for B deficiency
2 people found this helpful
Vitamin B50 is excellent! In the hospital, I dealt with fatigue and instability due to menopausal disorders and hypothyroidism. I was advised to take vitamin B50. Although I occasionally had B supplements, this B50 offers great value by combining multiple B vitamins. Many appear to lack vitamin B, hence, I strongly recommend it!
Read More
9
Energy boost
I enjoyed the B-complex! After dinner, I took a capsule. With hypothyroidism, I faced persistent fatigue, weakness, and irritability. After tests, I began addressing my group B and iron deficiencies since B vitamins assist with iron absorption. NOW's B-50 Complex is balanced and includes various B vitamins. I'll definitely be ordering more for my family!
Read More

Medical Researches

SCIENTIFIC SCORE
Possibly Effective
Based on 4 Researches
7.8
  • All Researches
9
Thiamine enhances memory in hypothyroidism
We explored the impact of thiamine (Vitamin B1) on memory and learning in rats with hypothyroidism. In a study involving 50 young rats, we treated them with a hypothyroid-inducing agent and varying doses of thiamine over seven weeks.

The results were promising—thiamine improved memory in rats as evidenced by better performance in timed tests. Specifically, higher doses of thiamine led to increased memory retention and reduced oxidative stress. This suggests that thiamine could be a beneficial supplement for addressing memory issues related to hypothyroidism.
Read More
8
Vitamin B benefits hypothyroidism treatment
We aimed to explore how B vitamins, including pyridoxine, betaine, folic acid, and cyanocobalamin, can correct homocysteine metabolism disrupted by hypothyroidism. By studying experimental rats treated for prolonged periods, we found that hypothyroidism severely reduced the activity of key enzymes involved in methylation, which in turn raised homocysteine levels—linked to heart disease risk.

Our findings indicate that B vitamins have a promising potential to lower these harmful homocysteine levels and could help prevent complications like endothelial dysfunction in hypothyroid patients.
Read More
7
Vitamin B12 deficiency linked to hypothyroidism
We explored the connection between vitamin B12 levels and hypothyroidism in a study involving 100 patients. A significant 68% of these patients were found to be vitamin B12 deficient, with a notable correlation to the presence of anti TPO and anti Thyroglobulin antibodies.

This suggests that vitamin B12 may play a role in the symptoms experienced by hypothyroid individuals, especially since thyroid hormones influence the production of red blood cells. While supplementation could potentially help alleviate these symptoms, further research is essential to confirm its effectiveness in routine treatment.
Read More
We examined the effects of Myo-inositol on autoimmune thyroiditis and hypothyroidism. Clinical studies indicated that combining Myo-inositol with seleniomethionine significantly reduced TSH levels in patients with subclinical hypothyroidism.

This treatment not only lowered TSH but also reduced antithyroid autoantibodies, suggesting a positive immune-modulatory effect. However, further research with larger populations is needed to better understand how this treatment impacts overall quality of life and to investigate the underlying mechanisms involved.
Read More

User Reviews

USERS' SCORE
Good
Based on 5 Reviews
8.6
  • All Reviews
  • Positive Reviews
  • Negative Reviews
9
Increased energy levels
114 people found this helpful
I liked the B-complex! After my lunch, I took one capsule. Having hypothyroidism, I often felt fatigued, weak, and irritable. Following tests, I addressed my deficiencies in vitamin B and iron, as B vitamins aid iron absorption. NOW B-50 complex is well-balanced with B-1, B-2, B-3, B-6, B-12, Biotin, Choline, Inositol, and Pantothenic Acid. After the course, I experienced a surge of energy that lasted throughout the day!
Read More
7.5
Recommended for B deficiency
2 people found this helpful
Vitamin B50 is excellent! In the hospital, I dealt with fatigue and instability due to menopausal disorders and hypothyroidism. I was advised to take vitamin B50. Although I occasionally had B supplements, this B50 offers great value by combining multiple B vitamins. Many appear to lack vitamin B, hence, I strongly recommend it!
Read More
9
Energy boost
I enjoyed the B-complex! After dinner, I took a capsule. With hypothyroidism, I faced persistent fatigue, weakness, and irritability. After tests, I began addressing my group B and iron deficiencies since B vitamins assist with iron absorption. NOW's B-50 Complex is balanced and includes various B vitamins. I'll definitely be ordering more for my family!
Read More
9
Improved strength
I found the B-complex excellent! Taking one capsule after dinner helped with my hypothyroidism, fatigue, and irritability. After tests, I focused on correcting my B and iron deficiencies, as B vitamins aid in iron absorption. NOW's B-50 Complex contains essential B vitamins. Following a course, I felt a surge in vitality!
Read More
7.5
Stress management
The B-complex is immensely beneficial for my hypothyroidism. I take a capsule after breakfast, avoiding other supplements to prevent incompatibility. I feel I'm coping better with stress and staying healthy!
Read More

Frequently Asked Questions

9
Increased energy levels
114 people found this helpful
I liked the B-complex! After my lunch, I took one capsule. Having hypothyroidism, I often felt fatigued, weak, and irritable. Following tests, I addressed my deficiencies in vitamin B and iron, as B vitamins aid iron absorption. NOW B-50 complex is well-balanced with B-1, B-2, B-3, B-6, B-12, Biotin, Choline, Inositol, and Pantothenic Acid. After the course, I experienced a surge of energy that lasted throughout the day!
7.5
Stress management
The B-complex is immensely beneficial for my hypothyroidism. I take a capsule after breakfast, avoiding other supplements to prevent incompatibility. I feel I'm coping better with stress and staying healthy!
9
Improved strength
I found the B-complex excellent! Taking one capsule after dinner helped with my hypothyroidism, fatigue, and irritability. After tests, I focused on correcting my B and iron deficiencies, as B vitamins aid in iron absorption. NOW's B-50 Complex contains essential B vitamins. Following a course, I felt a surge in vitality!
9
Energy boost
I enjoyed the B-complex! After dinner, I took a capsule. With hypothyroidism, I faced persistent fatigue, weakness, and irritability. After tests, I began addressing my group B and iron deficiencies since B vitamins assist with iron absorption. NOW's B-50 Complex is balanced and includes various B vitamins. I'll definitely be ordering more for my family!
7.5
Recommended for B deficiency
2 people found this helpful
Vitamin B50 is excellent! In the hospital, I dealt with fatigue and instability due to menopausal disorders and hypothyroidism. I was advised to take vitamin B50. Although I occasionally had B supplements, this B50 offers great value by combining multiple B vitamins. Many appear to lack vitamin B, hence, I strongly recommend it!
7
Vitamin B12 deficiency linked to hypothyroidism
We explored the connection between vitamin B12 levels and hypothyroidism in a study involving 100 patients. A significant 68% of these patients were found to be vitamin B12 deficient, with a notable correlation to the presence of anti TPO and anti Thyroglobulin antibodies.

This suggests that vitamin B12 may play a role in the symptoms experienced by hypothyroid individuals, especially since thyroid hormones influence the production of red blood cells. While supplementation could potentially help alleviate these symptoms, further research is essential to confirm its effectiveness in routine treatment.
8
Vitamin B benefits hypothyroidism treatment
We aimed to explore how B vitamins, including pyridoxine, betaine, folic acid, and cyanocobalamin, can correct homocysteine metabolism disrupted by hypothyroidism. By studying experimental rats treated for prolonged periods, we found that hypothyroidism severely reduced the activity of key enzymes involved in methylation, which in turn raised homocysteine levels—linked to heart disease risk.

Our findings indicate that B vitamins have a promising potential to lower these harmful homocysteine levels and could help prevent complications like endothelial dysfunction in hypothyroid patients.
We examined the effects of Myo-inositol on autoimmune thyroiditis and hypothyroidism. Clinical studies indicated that combining Myo-inositol with seleniomethionine significantly reduced TSH levels in patients with subclinical hypothyroidism.

This treatment not only lowered TSH but also reduced antithyroid autoantibodies, suggesting a positive immune-modulatory effect. However, further research with larger populations is needed to better understand how this treatment impacts overall quality of life and to investigate the underlying mechanisms involved.

References

  1. Saberi R, Mirazi N, Amirahmadi S, Darbandi ZK, Vafaee F, et al. Ameliorative effects of thiamin on learning behavior and memory dysfunction in a rat model of hypothyroidism: implication of oxidative stress and acetylcholinesterase. Metab Brain Dis. 2023;38:2603. doi:10.1007/s11011-023-01317-0
  2. Chatterjee T, Gupta R, Choudhary S. A Study on Vitamin B12 Levels in Hypothyroid Patients Presenting to a Tertiary Care Teaching Hospital. J Assoc Physicians India. 2023;71:1.
  3. Nechyporuk V, Korda M, Pentiuk L, Dmytrenko I, Bulko I. The impact of B vitamins on the functioning of methylation cycle in the liver and the kidneys of hyper- and hypothyroid rats. Pol Merkur Lekarski. 2020;48:55.
  4. Fallahi P, Ferrari SM, Elia G, Ragusa F, Paparo SR, et al. Myo-inositol in autoimmune thyroiditis, and hypothyroidism. Rev Endocr Metab Disord. 2018;19:349. doi:10.1007/s11154-018-9477-9
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