Overview

SCIENTIFIC SCORE
Possibly Effective
Based on 8 Researches
7.8
USERS' SCORE
Moderately Good
Based on 15 Reviews
7.9
Supplement Facts
Serving Size: 1 Veg Capsule
Amount Per Serving
%DV
Thiamin (Vitamin B-1) (from Thiamin HCl)
50 mg
4167%
Riboflavin (Vitamin B-2)
50 mg
3846%
Niacin (Vitamin B-3) (as Niacinamide)
50 mg
313%
Vitamin B-6 (from Pyridoxine HCl)
50 mg
2941%
Folate
680 mcg DFE (400 mcg folic acid)
170%
Vitamin B-12 (as Cyanocobalamin)
50 mcg
2083%
Biotin
50 mcg
167%
Pantothenic Acid (from Calcium Pantothenate)
50 mg
1000%
Choline (from Choline Bitartrate)
25 mg
5%
PABA (Para-Aminobenzoic Acid)
25 mg
Inositol
25 mg

Top Medical Research Studies

7
Investigating T-MSCs for menopause
We investigated if small extracellular vesicles (sEVs) derived from tonsil stem cells could improve myo-inositol production, which is often disrupted by inflammation in menopausal women.

Over two weeks, mice received treatments mimicking this condition. Our results indicated that those receiving sEVs showed a restoration of myo-inositol levels and healthier muscle profiles compared to those that did not.

This research suggests that sEVs could be a promising option to improve metabolic health during menopause.
Read More
7
Folate impacts bone health in menopause
We sought to understand how vitamin B levels influence bone health in postmenopausal women. Our analysis of 117 women over five years showed that higher folate levels positively correlate with vertebral bone mineral density changes.

However, we found no significant link between changes in bone density and either homocysteine or vitamin B12 levels. This suggests that folate deficiency may play a significant role in bone health during menopause, indicating its importance for maintaining vertebral strength.
Read More
9
Effective nutritional menopause treatment
We explored the effects of Exelvit Menopause®, a nutritional product incorporating various ingredients including vitamins and herbal extracts, on menopausal symptoms. Over 12 weeks, 156 menopausal women took this supplement daily, and we measured symptom relief using a standardized score.

Our findings revealed a noteworthy decrease in symptoms such as hot flashes, sleep disturbances, and irritability, with reductions ranging from 27.8% to 48.15%. This suggests that Exelvit Menopause® could offer a promising, non-hormonal approach to easing menopause-related discomfort.
Read More

Most Useful Reviews

9
Weight management
1 people found this helpful
I've been taking this for six months, with one tablet in the morning and one in the afternoon. I believe my weight is stabilising, and my cholesterol levels have normalised at my latest health check. This product may help with menopause symptoms, and it complements other supplements well.
Read More
9
Pain reduction
1 people found this helpful
As a post-menopausal woman, I've experienced significant finger and foot pain. Since taking this B50 supplement daily, the pain has remarkably lessened. It’s a delightful experience.
Read More
9
Fatigue reduction
This contains all the B vitamins I need in one daily tablet. Since starting it, I no longer feel easily fatigued. It’s also reassuring as it’s in a vegetable capsule, ideal for my menopause management.
Read More

Medical Researches

SCIENTIFIC SCORE
Possibly Effective
Based on 8 Researches
7.8
  • All Researches
9
Effective nutritional menopause treatment
We explored the effects of Exelvit Menopause®, a nutritional product incorporating various ingredients including vitamins and herbal extracts, on menopausal symptoms. Over 12 weeks, 156 menopausal women took this supplement daily, and we measured symptom relief using a standardized score.

Our findings revealed a noteworthy decrease in symptoms such as hot flashes, sleep disturbances, and irritability, with reductions ranging from 27.8% to 48.15%. This suggests that Exelvit Menopause® could offer a promising, non-hormonal approach to easing menopause-related discomfort.
Read More
We examined whether a combination of hyaluronic acid 0.3% and vitamin B12 could improve dry eye symptoms in menopausal women. In a study involving thirty women, we measured the effectiveness of a specially formulated eye drop containing these ingredients over a 30-day period.

After treatment, patients reported decreased symptoms and increased tear stability. Their scores on established dry eye assessment tools showed significant improvements, indicating that vitamin B12, alongside other ingredients, may play a beneficial role in alleviating dry eye issues during menopause.
Read More
8
Vitamin B may ease perimenopause
This randomized, double-blind, placebo-controlled study explored how a combination of the Amberen supplement and a vitamin B complex affects women in perimenopause suffering from climacteric symptoms.

We found that this dietary supplement is not only safe but also helps alleviate various symptoms like hot flashes and mood swings. Participants experienced improved sleep, cognitive function, and overall well-being.

Overall, this suggests that vitamin B complex can be a valuable part of managing perimenopausal symptoms.
Read More
8
Vitamin-enriched oil beneficial for menopause
We investigated the impact of vitamin-enriched extra virgin olive oil on postmenopausal women's health. In a year-long study involving 60 participants, half received the enriched oil while the other half got a placebo.

We found that those taking the vitamin-enriched olive oil showed improved platelet function and reduced levels of harmful nitrosative stress markers in their blood. This suggests that incorporating this healthy fat into our diets could help manage health issues related to menopause, particularly those affecting bone health.
Read More
7
Investigating T-MSCs for menopause
We investigated if small extracellular vesicles (sEVs) derived from tonsil stem cells could improve myo-inositol production, which is often disrupted by inflammation in menopausal women.

Over two weeks, mice received treatments mimicking this condition. Our results indicated that those receiving sEVs showed a restoration of myo-inositol levels and healthier muscle profiles compared to those that did not.

This research suggests that sEVs could be a promising option to improve metabolic health during menopause.
Read More

User Reviews

USERS' SCORE
Moderately Good
Based on 15 Reviews
7.9
  • All Reviews
  • Positive Reviews
  • Negative Reviews
9
Weight management
1 people found this helpful
I've been taking this for six months, with one tablet in the morning and one in the afternoon. I believe my weight is stabilising, and my cholesterol levels have normalised at my latest health check. This product may help with menopause symptoms, and it complements other supplements well.
Read More
9
Pain reduction
1 people found this helpful
As a post-menopausal woman, I've experienced significant finger and foot pain. Since taking this B50 supplement daily, the pain has remarkably lessened. It’s a delightful experience.
Read More
9
Fatigue reduction
This contains all the B vitamins I need in one daily tablet. Since starting it, I no longer feel easily fatigued. It’s also reassuring as it’s in a vegetable capsule, ideal for my menopause management.
Read More
7.5
Depression relief
3 people found this helpful
After my total hysterectomy, my estrogen plummeted, leading to an early menopause and a series of depressive symptoms. Life was challenging until I incorporated B50, vitamin C, B6, and magnesium into my routine, which alleviated my depression. I hope my review assists others.
Read More
7.5
Energy boost
1 people found this helpful
Post-menopause, I realised the need to supplement with B vitamins. Since doing so, my numbness has disappeared. B vitamins act as fuel for energy metabolism, and I've felt revitalised after ensuring adequate intake.
Read More

Frequently Asked Questions

6
Nerve protection
I took this to protect my nerves during menopause, as I've been suffering from paresthesia. After about two weeks, my symptoms have become less severe.
7.5
Mobility improvement
Since my late 40s, I’ve faced neck stiffness and hand numbness. I turned to B vitamins for relief and found Now Foods' B50 a cost-effective choice. After two weeks, my symptoms improved significantly, and I can now move more freely.
9
Weight management
1 people found this helpful
I've been taking this for six months, with one tablet in the morning and one in the afternoon. I believe my weight is stabilising, and my cholesterol levels have normalised at my latest health check. This product may help with menopause symptoms, and it complements other supplements well.
9
Pain reduction
1 people found this helpful
As a post-menopausal woman, I've experienced significant finger and foot pain. Since taking this B50 supplement daily, the pain has remarkably lessened. It’s a delightful experience.
6
Dizziness relief
1 people found this helpful
I've experienced dizziness due to menopause, but regular B-50 intake has significantly reduced its occurrence. I stopped taking it at one point but noticed the positive effects when I resumed.
7.5
Depression relief
3 people found this helpful
After my total hysterectomy, my estrogen plummeted, leading to an early menopause and a series of depressive symptoms. Life was challenging until I incorporated B50, vitamin C, B6, and magnesium into my routine, which alleviated my depression. I hope my review assists others.
7.5
Energy boost
1 people found this helpful
Post-menopause, I realised the need to supplement with B vitamins. Since doing so, my numbness has disappeared. B vitamins act as fuel for energy metabolism, and I've felt revitalised after ensuring adequate intake.
9
Effective nutritional menopause treatment
We explored the effects of Exelvit Menopause®, a nutritional product incorporating various ingredients including vitamins and herbal extracts, on menopausal symptoms. Over 12 weeks, 156 menopausal women took this supplement daily, and we measured symptom relief using a standardized score.

Our findings revealed a noteworthy decrease in symptoms such as hot flashes, sleep disturbances, and irritability, with reductions ranging from 27.8% to 48.15%. This suggests that Exelvit Menopause® could offer a promising, non-hormonal approach to easing menopause-related discomfort.
8
Vitamin B may ease perimenopause
This randomized, double-blind, placebo-controlled study explored how a combination of the Amberen supplement and a vitamin B complex affects women in perimenopause suffering from climacteric symptoms.

We found that this dietary supplement is not only safe but also helps alleviate various symptoms like hot flashes and mood swings. Participants experienced improved sleep, cognitive function, and overall well-being.

Overall, this suggests that vitamin B complex can be a valuable part of managing perimenopausal symptoms.
7
Vitamin B6 linked to mood improvement
We explored how dietary vitamin B6 intake affects depression and anxiety in middle-aged and elderly Japanese women. In our cross-sectional study with 289 participants, we found that higher consumption of vitamin B6 was linked to reduced moderate to severe depressive symptoms.

Interestingly, this connection remained even after considering age and menopausal status, making it clear that boosting our vitamin B6 intake might be beneficial for improving mood during menopause.
7
Folate impacts bone health in menopause
We sought to understand how vitamin B levels influence bone health in postmenopausal women. Our analysis of 117 women over five years showed that higher folate levels positively correlate with vertebral bone mineral density changes.

However, we found no significant link between changes in bone density and either homocysteine or vitamin B12 levels. This suggests that folate deficiency may play a significant role in bone health during menopause, indicating its importance for maintaining vertebral strength.

References

  1. Cho KA, Kim YH, Woo SY, Ryu KH. Tonsil-Derived Mesenchymal Stem Cell-Derived Small Extracellular Vesicles (sEVs) Restore Myo-Inositol Production in LPS-Treated Skeletal Muscle. Tissue Eng Regen Med. 2025. 10.1007/s13770-025-00709-w
  2. Kachko VA, Shulman LP, Kuznetsova IV, Uspenskaya YB, Burchakov DI. Clinical Evaluation of Effectiveness and Safety of Combined Use of Dietary Supplements Amberen and Smart B in Women with Climacteric Syndrome in Perimenopause. Adv Ther. 2024;41:3183. 10.1007/s12325-024-02910-0
  3. Palacios S, Mustata C, Rizo JM, Regidor PA. Improvement in menopausal symptoms with a nutritional product containing evening primrose oil, hop extract, saffron, tryptophan, vitamins B6, D3, K2, B12, and B9. Eur Rev Med Pharmacol Sci. 2023;27:8180. 10.26355/eurrev_202309_33578
  4. De-Hita-Cantalejo C, Sánchez-González MC, Silva-Viguera C, García-Romera MC, Feria-Mantero R, et al. Efficacy of hyaluronic acid 0.3%, cyanocobalamin, electrolytes, and P-Plus in menopause patients with moderate dry eye disease. Graefes Arch Clin Exp Ophthalmol. 2022;260:529. 10.1007/s00417-021-05415-6
  5. Odai T, Terauchi M, Suzuki R, Kato K, Hirose A, et al. Depressive Symptoms in Middle-Aged and Elderly Women Are Associated with a Low Intake of Vitamin B6: A Cross-Sectional Study. Nutrients. 2020;12. 10.3390/nu12113437
  6. Vignini A, Nanetti L, Raffaelli F, Sabbatinelli J, Salvolini E, et al. Effect of 1-y oral supplementation with vitaminized olive oil on platelets from healthy postmenopausal women. Nutrition. 2017;42:92. 10.1016/j.nut.2017.06.013
  7. McCabe D, Lisy K, Lockwood C, Colbeck M. The impact of essential fatty acid, B vitamins, vitamin C, magnesium and zinc supplementation on stress levels in women: a systematic review. JBI Database System Rev Implement Rep. 2017;15:402. 10.11124/JBISRIR-2016-002965
  8. Cagnacci A, Bagni B, Zini A, Cannoletta M, Generali M, et al. Relation of folates, vitamin B12 and homocysteine to vertebral bone mineral density change in postmenopausal women. A five-year longitudinal evaluation. Bone. 2008;42:314. 10.1016/j.bone.2007.10.022
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