Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 9 Researches
7.7
USERS' SCORE
Good
Based on 3 Reviews
8.4
Supplement Facts
Serving Size: 1 Veg Capsule
Amount Per Serving
%DV
Thiamin (Vitamin B-1) (from Thiamin HCl)
50 mg
4167%
Riboflavin (Vitamin B-2)
50 mg
3846%
Niacin (Vitamin B-3) (as Niacinamide)
50 mg
313%
Vitamin B-6 (from Pyridoxine HCl)
50 mg
2941%
Folate
680 mcg DFE (400 mcg folic acid)
170%
Vitamin B-12 (as Cyanocobalamin)
50 mcg
2083%
Biotin
50 mcg
167%
Pantothenic Acid (from Calcium Pantothenate)
50 mg
1000%
Choline (from Choline Bitartrate)
25 mg
5%
PABA (Para-Aminobenzoic Acid)
25 mg
†
Inositol
25 mg
†
Top Medical Research Studies
9
We investigated the impact of combined B-vitamin supplementation—specifically folic acid, vitamin B12, and vitamin B6—on stroke prevention. Through a thorough analysis of 14 randomized controlled trials, we found that these vitamins significantly reduced stroke risk, especially in areas lacking folic acid fortification.
Dosages below 0.8 mg/day for folic acid and 0.4 mg/day for vitamin B12 appeared to be the most effective. However, no benefits were seen in areas where fortification was already implemented. This suggests that while B vitamins can be beneficial, their effectiveness relies heavily on dietary conditions.
Dosages below 0.8 mg/day for folic acid and 0.4 mg/day for vitamin B12 appeared to be the most effective. However, no benefits were seen in areas where fortification was already implemented. This suggests that while B vitamins can be beneficial, their effectiveness relies heavily on dietary conditions.
Read More
8
We explored the effects of folic acid supplementation on stroke prevention through an analysis of 21 randomized controlled trials involving over 115,000 participants. Overall, we observed that folic acid significantly reduced stroke risk by about 10%.
Interestingly, the benefits were most pronounced in regions without fortified grains and among those without a prior history of stroke. Our findings suggest that grain fortification and individual health history play important roles in how effective folic acid can be for preventing strokes.
Interestingly, the benefits were most pronounced in regions without fortified grains and among those without a prior history of stroke. Our findings suggest that grain fortification and individual health history play important roles in how effective folic acid can be for preventing strokes.
Read More
9.5
We explored the connection between platelet levels, genetic factors, and the effectiveness of folic acid in preventing strokes. Using data from over 11,000 hypertensive patients, we found that those with low platelet counts and specific genetic markers showed the highest stroke risks. However, they also experienced significant benefits from folic acid treatment, with notable reductions in stroke occurrence. This suggests that understanding an individual’s platelet function may help identify who can benefit most from folic acid therapy in stroke prevention efforts.
Read More
Most Useful Reviews
9
Effective vitamin solution
2 people found this helpful
An excellent complex of B vitamins; I purchased it for my mother, who experiences constant cramps in her legs and arms following a stroke. It became clear that these vital vitamins are beneficial for her condition. This complex truly presents an excellent solution to our problem, and the vitamins have positively impacted her.
Read More
7.5
Supports nervous system
A good selection of B vitamins along with choline and inositol, which help energy production, maintain a healthy nervous system, and support normal homocysteine metabolism. Vitamin B1 is crucial for the nervous system, while B6 aids in treating neurological disorders and depression. Vitamin B12 is vital for preventing anaemia and stroke, normalising nervous system functions. For vegans, such supplements are a crucial way to obtain the full spectrum of B vitamins. Grateful to Now Foods for an excellent product; I will certainly repurchase.
Read More
7.5
Improved mood and energy
B vitamins from Now Foods are essential for everyone. They help reduce the risks of severe diseases, calm the nerves, prevent strokes and heart attacks, and improve memory. Each package contains 100 capsules, and I take one each morning. This has enhanced my mood, energy levels, and overall performance.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 9 Researches
7.7
- All Researches
9.5
We explored the connection between platelet levels, genetic factors, and the effectiveness of folic acid in preventing strokes. Using data from over 11,000 hypertensive patients, we found that those with low platelet counts and specific genetic markers showed the highest stroke risks. However, they also experienced significant benefits from folic acid treatment, with notable reductions in stroke occurrence. This suggests that understanding an individual’s platelet function may help identify who can benefit most from folic acid therapy in stroke prevention efforts.
Read More
9
We investigated the impact of combined B-vitamin supplementation—specifically folic acid, vitamin B12, and vitamin B6—on stroke prevention. Through a thorough analysis of 14 randomized controlled trials, we found that these vitamins significantly reduced stroke risk, especially in areas lacking folic acid fortification.
Dosages below 0.8 mg/day for folic acid and 0.4 mg/day for vitamin B12 appeared to be the most effective. However, no benefits were seen in areas where fortification was already implemented. This suggests that while B vitamins can be beneficial, their effectiveness relies heavily on dietary conditions.
Dosages below 0.8 mg/day for folic acid and 0.4 mg/day for vitamin B12 appeared to be the most effective. However, no benefits were seen in areas where fortification was already implemented. This suggests that while B vitamins can be beneficial, their effectiveness relies heavily on dietary conditions.
Read More
8
We examined the link between folate concentrations and the risk of stroke in a study involving over 4,900 participants from a Chinese community.
By tracking these individuals for nearly a decade, we observed that those with higher folate levels had a lower chance of experiencing strokes.
Notably, levels of homocysteine (Hcy) contributed to this relationship, mediating a significant portion of the effect. Furthermore, we found that the impact of folate on stroke risk varied depending on specific genetic factors.
Overall, low folate levels appeared to increase the risk of stroke over ten years, suggesting a potential role for folate in stroke prevention.
By tracking these individuals for nearly a decade, we observed that those with higher folate levels had a lower chance of experiencing strokes.
Notably, levels of homocysteine (Hcy) contributed to this relationship, mediating a significant portion of the effect. Furthermore, we found that the impact of folate on stroke risk varied depending on specific genetic factors.
Overall, low folate levels appeared to increase the risk of stroke over ten years, suggesting a potential role for folate in stroke prevention.
Read More
8
We explored the connection between folate, homocysteine levels, and outcomes in over 3,500 patients who suffered ischemic strokes. Our analysis found that higher folate levels were associated with a 29% decrease in the risk of severe outcomes, like death or major disability, at three months post-stroke.
Conversely, increased homocysteine levels correlated with a 52% higher risk of such outcomes. Notably, about 25.5% of the positive effects of folate were influenced by homocysteine. Overall, boosting folate could be beneficial for stroke recovery.
Conversely, increased homocysteine levels correlated with a 52% higher risk of such outcomes. Notably, about 25.5% of the positive effects of folate were influenced by homocysteine. Overall, boosting folate could be beneficial for stroke recovery.
Read More
8
We explored the effects of folic acid supplementation on stroke prevention through an analysis of 21 randomized controlled trials involving over 115,000 participants. Overall, we observed that folic acid significantly reduced stroke risk by about 10%.
Interestingly, the benefits were most pronounced in regions without fortified grains and among those without a prior history of stroke. Our findings suggest that grain fortification and individual health history play important roles in how effective folic acid can be for preventing strokes.
Interestingly, the benefits were most pronounced in regions without fortified grains and among those without a prior history of stroke. Our findings suggest that grain fortification and individual health history play important roles in how effective folic acid can be for preventing strokes.
Read More
User Reviews
USERS' SCORE
Good
Based on 3 Reviews
8.4
- All Reviews
- Positive Reviews
- Negative Reviews
9
Effective vitamin solution
2 people found this helpful
An excellent complex of B vitamins; I purchased it for my mother, who experiences constant cramps in her legs and arms following a stroke. It became clear that these vital vitamins are beneficial for her condition. This complex truly presents an excellent solution to our problem, and the vitamins have positively impacted her.
Read More
7.5
Supports nervous system
A good selection of B vitamins along with choline and inositol, which help energy production, maintain a healthy nervous system, and support normal homocysteine metabolism. Vitamin B1 is crucial for the nervous system, while B6 aids in treating neurological disorders and depression. Vitamin B12 is vital for preventing anaemia and stroke, normalising nervous system functions. For vegans, such supplements are a crucial way to obtain the full spectrum of B vitamins. Grateful to Now Foods for an excellent product; I will certainly repurchase.
Read More
7.5
Improved mood and energy
B vitamins from Now Foods are essential for everyone. They help reduce the risks of severe diseases, calm the nerves, prevent strokes and heart attacks, and improve memory. Each package contains 100 capsules, and I take one each morning. This has enhanced my mood, energy levels, and overall performance.
Read More
Frequently Asked Questions
9
Effective vitamin solution
2 people found this helpful
An excellent complex of B vitamins; I purchased it for my mother, who experiences constant cramps in her legs and arms following a stroke. It became clear that these vital vitamins are beneficial for her condition. This complex truly presents an excellent solution to our problem, and the vitamins have positively impacted her.
7.5
Improved mood and energy
B vitamins from Now Foods are essential for everyone. They help reduce the risks of severe diseases, calm the nerves, prevent strokes and heart attacks, and improve memory. Each package contains 100 capsules, and I take one each morning. This has enhanced my mood, energy levels, and overall performance.
7.5
Supports nervous system
A good selection of B vitamins along with choline and inositol, which help energy production, maintain a healthy nervous system, and support normal homocysteine metabolism. Vitamin B1 is crucial for the nervous system, while B6 aids in treating neurological disorders and depression. Vitamin B12 is vital for preventing anaemia and stroke, normalising nervous system functions. For vegans, such supplements are a crucial way to obtain the full spectrum of B vitamins. Grateful to Now Foods for an excellent product; I will certainly repurchase.
8
We explored the effects of folic acid supplementation on stroke prevention through an analysis of 21 randomized controlled trials involving over 115,000 participants. Overall, we observed that folic acid significantly reduced stroke risk by about 10%.
Interestingly, the benefits were most pronounced in regions without fortified grains and among those without a prior history of stroke. Our findings suggest that grain fortification and individual health history play important roles in how effective folic acid can be for preventing strokes.
Interestingly, the benefits were most pronounced in regions without fortified grains and among those without a prior history of stroke. Our findings suggest that grain fortification and individual health history play important roles in how effective folic acid can be for preventing strokes.
8
We explored the connection between folate, homocysteine levels, and outcomes in over 3,500 patients who suffered ischemic strokes. Our analysis found that higher folate levels were associated with a 29% decrease in the risk of severe outcomes, like death or major disability, at three months post-stroke.
Conversely, increased homocysteine levels correlated with a 52% higher risk of such outcomes. Notably, about 25.5% of the positive effects of folate were influenced by homocysteine. Overall, boosting folate could be beneficial for stroke recovery.
Conversely, increased homocysteine levels correlated with a 52% higher risk of such outcomes. Notably, about 25.5% of the positive effects of folate were influenced by homocysteine. Overall, boosting folate could be beneficial for stroke recovery.
9.5
We explored the connection between platelet levels, genetic factors, and the effectiveness of folic acid in preventing strokes. Using data from over 11,000 hypertensive patients, we found that those with low platelet counts and specific genetic markers showed the highest stroke risks. However, they also experienced significant benefits from folic acid treatment, with notable reductions in stroke occurrence. This suggests that understanding an individual’s platelet function may help identify who can benefit most from folic acid therapy in stroke prevention efforts.
9
We investigated the impact of combined B-vitamin supplementation—specifically folic acid, vitamin B12, and vitamin B6—on stroke prevention. Through a thorough analysis of 14 randomized controlled trials, we found that these vitamins significantly reduced stroke risk, especially in areas lacking folic acid fortification.
Dosages below 0.8 mg/day for folic acid and 0.4 mg/day for vitamin B12 appeared to be the most effective. However, no benefits were seen in areas where fortification was already implemented. This suggests that while B vitamins can be beneficial, their effectiveness relies heavily on dietary conditions.
Dosages below 0.8 mg/day for folic acid and 0.4 mg/day for vitamin B12 appeared to be the most effective. However, no benefits were seen in areas where fortification was already implemented. This suggests that while B vitamins can be beneficial, their effectiveness relies heavily on dietary conditions.
References
- Liang Z, Fan F, Liu B, Li K, Chen H, et al. Association Between Serum Folate Concentrations and 10-Year Stroke Risk in a Prospective Community Cohort: Mediation and Interaction Analyses. Nutrients. 2024;17. doi:10.3390/nu17010159
- Shi M, Zheng J, Liu Y, Mao X, Wu X, et al. Folate, Homocysteine, and Adverse Outcomes After Ischemic Stroke. J Am Heart Assoc. 2024;13:e036527. doi:10.1161/JAHA.124.036527
- Jung E, Kook HY, Ryu SJ, Ryu HH, Kim HG. The Association of Vitamin B-12 Plasma Concentration with Stroke Incidence According to Sex. J Nutr. 2024;154:3012. doi:10.1016/j.tjnut.2024.08.002
- Zhang N, Zhou Z, Chi X, Fan F, Li S, et al. Folic acid supplementation for stroke prevention: A systematic review and meta-analysis of 21 randomized clinical trials worldwide. Clin Nutr. 2024;43:1706. doi:10.1016/j.clnu.2024.05.034
- Martínez-Torres NI, Cárdenas-Bedoya J, Torres-Mendoza BM. Acute Combined Cerebrolysin and Nicotinamide Administration Promote Cognitive Recovery Through Neuronal Changes in the Hippocampus of Rats with Permanent Middle Cerebral Artery Occlusion. Neuroscience. 2024;549:76. doi:10.1016/j.neuroscience.2024.05.006
- Zhang X, Zhang Q, Zhang Q, Wang H, Yin Y, et al. Tetrahydrofolate Attenuates Cognitive Impairment after Hemorrhagic Stroke by Promoting Hippocampal Neurogenesis via PTEN Signaling. eNeuro. 2024;11. doi:10.1523/ENEURO.0021-24.2024
- Shi Y, Zhang Z, Wang B, Wang Y, Kong X, et al. Effect of plateletcrit and methylenetetrahydrofolate reductase (MTHFR) C677T genotypes on folic acid efficacy in stroke prevention. Signal Transduct Target Ther. 2024;9:110. doi:10.1038/s41392-024-01817-0
- Zhang N, Wu Z, Bai X, Song Y, Li P, et al. Dosage exploration of combined B-vitamin supplementation in stroke prevention: a meta-analysis and systematic review. Am J Clin Nutr. 2024;119:821. doi:10.1016/j.ajcnut.2023.12.021
- Tripathi S, Nath M, Misra S, Kumar P. From A to E: Uniting vitamins against stroke risk-A systematic review and network meta-analysis. Eur J Clin Invest. 2024;54:e14165. doi:10.1111/eci.14165
