NOW Supplements Vitamin A

Vitamin A and allergy management

Based on 11 Researches

Lotfi R. Retinoic Acid (RA): A Critical Immunoregulatory Molecule in Asthma and Allergies. Immun Inflamm Dis. 2024;12:e70051. doi:10.1002/iid3.70051

Our exploration into the effects of vitamin A, particularly its active form known as retinoic acid, revealed some interesting insights regarding allergies. Vitamin A plays a key role in our immune system by helping to regulate immune responses, which is crucial for managing allergic reactions.

Research indicates that retinoic acid can promote the development of regulatory T cells, which are essential for maintaining balance in our immune system. These T cells help to suppress excessive immune responses that can lead to allergies. Additionally, they assist in managing inflammatory responses, which is particularly important for conditions like asthma and allergic reactions.

Notably, studies have shown that levels of retinoic acid are often lower in individuals suffering from asthma and allergies. Moreover, introducing retinoic acid as a treatment has been found to alleviate symptoms associated with allergies and reduce airway inflammation. This suggests that boosting retinoic acid levels in the body might be a promising therapeutic approach for those dealing with allergic conditions.

Overall, we conclude that vitamin A—through its derivative retinoic acid—holds significant potential for improving allergy management by enhancing immune regulation.

Winter nose issues

Most Useful Review

1 people found this helpful

I loved this vitamin A, as it alleviated my winter nose problems and allergies. I recommend it to anyone experiencing similar issues.

Updated: Mar 2026

Anemia details

Vitamin A's role in anemia

Based on 7 Researches

Mejia LA, Erdman JW. Impact of Vitamin A Deficiency on Iron Metabolism and Anemia: A Historical Perspective and Research Advances. Nutr Rev. 2025;83:577. doi:10.1093/nutrit/nuae183

We examined the connection between vitamin A deficiency (VAD) and anemia, particularly how a lack of vitamin A can impact iron metabolism in our bodies. Through reviewing existing research, we discovered that VAD doesn't just lead to general anemia but may cause a specific type known as vitamin A deficiency anemia (VADA).

Our findings reveal that vitamin A plays an essential role in the production of red blood cells. When we lack vitamin A, our bodies struggle to utilize iron effectively. Instead of being available for red blood cell production, iron accumulates in our liver and spleen, leading to reduced levels of circulating iron.

We also saw that inflammation and systemic infections could further exacerbate this issue by triggering the liver to produce more hepcidin, a protein that regulates iron levels. The excess hepcidin can create a situation where there isn’t enough iron for the production of hemoglobin, ultimately causing anemia.

Interestingly, our review highlighted that VADA happens not because of a lack of iron, but due to how iron is managed within the body. By understanding these mechanisms, we can work towards creating better strategies to tackle anemia on a global scale.

Essential for absorption

Most Useful Review

2 people found this helpful

The best vitamin A supplement is vitamin E (tocopherol). This combination allows for quicker absorption. It’s crucial to control doses and take vitamin C, as this pairing improves iron absorption, vital for combating anemia. I typically take these supplements twice a year, during spring and autumn.

Updated: Mar 2026

Chronic Cough details

Improved chronic cough

21 people found this helpful

Respite Vitamin A is essential for mucous membranes, so I purchased it for my husband with severe asthma. I struggled to sleep due to suffocation, but after taking 100,000 IU daily, I noticed a significant improvement within a month. His daytime cough has also decreased dramatically. However, high doses of vitamin A can result in vitamin K deficiency, so I recommend consuming natto alongside it.

Cough details

Vitamin A increases cough incidence

Based on 11 Researches

Long KZ, Montoya Y, Hertzmark E, Santos JI, Rosado JL. A double-blind, randomized, clinical trial of the effect of vitamin A and zinc supplementation on diarrheal disease and respiratory tract infections in children in Mexico City, Mexico. Am J Clin Nutr. 2006;83:693.

We examined how vitamin A and zinc supplementation influences cough and other health issues in young children. In a carefully designed study involving 736 children in Mexico City, we found that vitamin A actually led to a 23% increase in cough with fever.

Surprisingly, while vitamin A raised rates of cough and diarrhea, zinc showed no impact on these conditions. Our findings suggest that vitamin A's effects can vary significantly depending on a child's living situation and household characteristics.

Cough relief achieved

Most Useful Review

4 people found this helpful

Stopped my cough of 20 years within 5 days of purchase. I had a chronic cough for two decades, visiting numerous doctors and undergoing countless tests, yet nothing helped. After reading an article suggesting 100,000 IU with 2 grams of crystallised Vitamin C three times daily, I decided to try it myself in addition to helping my husband recover from bronchitis. By the second dose, I had not coughed again. While it did return 50% after lowering the dosage, it was nothing like before. I appreciate purchasing it online as it is more affordable than health stores, though I remain slightly concerned about its toxicity.

Updated: Mar 2026

Hypothyroidism details

Vitamin A benefits thyroid function

Based on 12 Researches

Farhangi MA, Keshavarz SA, Eshraghian M, Ostadrahimi A, Saboor-Yaraghi AA. The effect of vitamin A supplementation on thyroid function in premenopausal women. J Am Coll Nutr. 2012;31:268.

We conducted a thorough investigation into how vitamin A supplementation might impact thyroid function, particularly focusing on women who are premenopausal and have varying body weights. Our study was a robust, four-month randomized controlled trial involving 84 healthy women aged 17 to 50. Among them, 56 women were classified as obese, while 28 fell into the nonobese category.

Throughout the study, we administered 25,000 IU of vitamin A or a placebo to the obese participants, while nonobese participants received vitamin A as well. Before and after the supplementation period, we measured key thyroid markers, including thyroid-stimulating hormone (TSH), total thyroxine (T4), total triiodothyronine (T3), and proteins associated with vitamin A transport.

Our findings revealed that vitamin A supplementation significantly reduced TSH concentrations in both the obese and nonobese groups, suggesting it may help mitigate the risk of subclinical hypothyroidism. Interestingly, we also noticed an increase in serum T3 levels among those treated with vitamin A. However, T4 levels decreased across all groups, including those not receiving vitamin A.

Overall, it appears that vitamin A may serve as a beneficial intervention for thyroid function in women, particularly those at risk for hypothyroidism. This research highlights an accessible avenue to better support thyroid health through dietary supplementation.

Improved vitamin levels

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10 people found this helpful

Working drug! My doctor said, "Vitamin A is essential for your mucous membranes." My vitamin A levels have significantly increased, which is crucial for someone with hypothyroidism. The capsules are small and easy to take; I also ensure to take them with fats for better absorption.

Updated: Mar 2026

Irritable Bowel Syndrome details

6 people found this helpful

I take this Vitamin A for my blepharitis or dry eye syndrome, which I've suffered from for some time. It has significantly helped in the last few weeks. I've also begun using Organic Egyptian Carrot Seed Oil in my eyes with great results. We all require Vitamin A, as many vital nutrients are absent from our diets now. If you have eye problems, I recommend trying this.

Whooping Cough details

Chronic cough eliminated

2 people found this helpful

This supplement significantly improved my immunity and, most importantly, cured my chronic cough that I struggled to eliminate for a long time. Now, I occasionally take these capsules to prevent respiratory illnesses and boost my immunity. I recommend it to anyone who frequently gets sick. Benefits include strengthened immune system and elimination of a chronic cough; I found no disadvantages.

Cataract details

Vitamin A improves post-surgery vision

Based on 5 Researches

Yamada F, Kato K, Nagashima R, Yonekawa Y, Kashima Y, et al. Case of persistent corneal epithelial damage after cataract surgery leading to diagnosis of vitamin A deficiency. Doc Ophthalmol. 2024;148:121. doi:10.1007/s10633-023-09963-6

We analyzed a case involving a 74-year-old man who experienced ongoing blurred vision after cataract surgery. His condition included persistent damage to the corneal epithelium, which raised concerns over the underlying reasons for his visual impairment.

To investigate, we recorded his full-field electroretinograms (ff-ERGs) to assess both scotopic and photopic responses of the retina. We also performed optical coherence tomography (OCT) to visualize changes in his retinal structure. Laboratory tests revealed a critically low level of vitamin A in his blood.

Given these findings, we diagnosed him with vitamin A deficiency (VAD) and initiated treatment with oral vitamin A supplements. Remarkably, after three months, we noted significant improvements: his visual acuity, ff-ERGs, and OCT results returned to normal. This highlighted the potential of vitamin A in managing visual issues related to cataract surgery.

Our findings suggest that vitamin A plays an important role in recovery from eye surgeries, especially for patients like him who experience corneal damage and impaired vision. We believe this case underscores the importance of monitoring vitamin A levels in patients presenting with similar complications.

Positive progress

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2 people found this helpful

Just what the doctor ordered! With my cataracts, I came across an article advising the intake of 25,000 i.u. of Vitamin A, not sourced from Beta Carotene. I searched and found this product that meets my needs. Since using it alongside some eye drops, I've noticed improvement, which is all I could ask for.

Updated: Mar 2026

Chest Pain details

7 people found this helpful

No way did I expect this vitamin A to help with my vision and mucous membranes, but it remarkably relieved my chest pain from hernias. Within four days of taking it, my long-standing back pain also vanished. After a brief break, it worked immediately when I reintroduced it after a minor back injury. Although I’m not sure about my eyesight, my skin looks cleaner. I believe the combination with B vitamins is beneficial.

6 people found this helpful

Cold Sores details

I suffer from dry mucous membranes in my throat and nose, which often leads to cold sores and feeling unwell. Initially, I took a small dose, but found that 25,000 to 50,000 IU is effective, especially in winter. This supplement has significantly reduced my colds and improved my overall health.

Eczema details

Alitretinoin improves eczema treatment

Based on 9 Researches

Kislat A, Olah P, Kuchner M, Gerber PA, Schrader J, et al. The Endogenous Dual Retinoid Receptor Agonist Alitretinoin Exhibits Immunoregulatory Functions on Antigen-Presenting Cells. Int J Mol Sci. 2023;24. doi:10.3390/ijms24119654

We explored the effects of alitretinoin, a form of vitamin A, on chronic hand eczema (CHE). This powerful drug is known to target specific receptors in the skin, offering insights into its method of action. Through our detailed study, we examined skin samples from patients who responded well to alitretinoin treatment.

Our analysis revealed a total of 231 genes that were markedly regulated. We found that alitretinoin primarily impacts keratinocytes, the skin's primary cells, by addressing inflammation and enhancing skin barrier function. This treatment improved the expression of certain protective proteins while fostering the production of hyaluronic acid, a substance that helps hydrate and soothe the skin.

Furthermore, we observed that alitretinoin also affects immune cells, particularly dendritic cells, which play a vital role in our immune response. These cells, when treated with alitretinoin, displayed unique alterations in their appearance and function. They had lower levels of specific markers that typically spur an immune response and stimulated the production of IL-10, a cytokine that promotes immune tolerance. Most impressively, these treated cells were less effective at activating T cells, which are crucial for initiating inflammation.

Our findings indicate that alitretinoin not only treats the visible symptoms of eczema but also helps regulate the immune response, providing a dual approach in the management of chronic hand eczema. Ultimately, these insights show that vitamin A treatment holds significant promise for improving outcomes in eczema patients.

Cured hand eczema

Most Useful Review

Particularly effective for hand eczema. My hand eczema is now completely cured. Previously, 20,000 IU wasn’t effective, but along with zinc, I've seen complete results.

Updated: Mar 2026

Floaters details

Excellent effect! Before I knew it, my floaters had disappeared. It’s extremely effective, and I also recommend it to my family.

Measles details

Vitamin A ineffective in measles treatment

Based on 4 Researches

Lo Vecchio A, Cambriglia MD, Bruzzese D, Guarino A. Vitamin A in Children Hospitalized for Measles in a High-income Country. Pediatr Infect Dis J. 2021;40:723. doi:10.1097/INF.0000000000003156

We conducted a study to evaluate if vitamin A could improve outcomes for children hospitalized with measles in a high-income country. We followed 108 children at a hospital in Southern Italy, comparing those who received vitamin A to a control group. Unfortunately, we found no meaningful differences in fever duration, hospitalization length, or complication rates between the two groups. Ultimately, our results suggest that vitamin A supplementation does not alter the course of measles in these cases.

Facilitates measles recovery

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1 people found this helpful

Helps with measles! I ordered this after receiving recommendations for nursing during measles. In the initial two days of illness, children under seven should receive 40,000 IU, while those over need 60,000 IU, followed by a daily dose of 25,000 IU. The retinol form is the most easily absorbed and effective!

Updated: Mar 2026

Psoriasis details

2 people found this helpful

Vitamin A in its retinol form has a 90% absorption rate, compared to 50% for beta-carotene, making it safer and suitable for thrice-weekly use. This has an excellent effect on epithelial and corneal cells, particularly beneficial for those with psoriasis. It is advisable to combine it with vitamin E at separate meals and to ensure adequate water intake.

Reflux details

No reflux experienced

Now Brand has demonstrated to me that their products are natural with no side effects, particularly the krill oil, which is tasteless and does not cause reflux or unpleasant odour.

Warts details

Vitamin A shows limited wart benefits

Based on 6 Researches

Gross G, Pfister H, Hagedorn M, Stahn R. Effect of oral aromatic retinoid (Ro 10-9359) on human papilloma virus-2-induced common warts. Dermatologica. 1983;166:48.

We explored the impact of the oral aromatic retinoid, Ro 10-9359, on common warts caused by human papilloma virus (HPV) 2 in a patient with chronic lymphatic leukemia.

The treatment led to rapid improvement, with no detectable viral particles or DNA during the therapy. However, the treatment had to stop due to the patient's development of a liposarcoma, leading to a relapse of the warts.

Notably, the same HPV-2 subtype was present before and after the treatment, suggesting limited long-term effectiveness.

Warts disappeared

Most Useful Review

47 people found this helpful

I have experienced significant dryness in my nose and throat for the past two years, alongside an uncomfortable feeling in my eyes and a wrinkled wart. Initially, I believed the dryness in my nose was due to winter humidity. I encountered nasal discharge mixed with blood, despite not having a blocked nose, and was diagnosed with Graves’ disease and hay fever. In my attempt to combat inflammation, I used cortisol, which worsened my condition. Eventually, I began taking vitamin A, which led to a noticeable improvement. To my surprise, the wart contracted and vanished, my dry skin ceased, and my nasal mucosa felt less irritated. Remarkably, my menstrual bleeding diminished. I feel vitamin A is crucial for addressing various health issues, including the depletion linked to my condition.

Updated: Mar 2026

Weight Loss details

Skin elasticity restored

Excellent! The effect is remarkable! After significant weight loss, my skin's elasticity quickly returned. Combined with vitamins C and E, it serves as a powerful antioxidant. I highly recommend it.

Attention Deficit Hyperactivity Disorder details

Supports overall health

NOW Foods Vitamin A 25,000 IU Softgels are an excellent dietary supplement providing a potent source of vitamin A in a convenient form. Each softgel contains enough vitamin A to meet the daily recommendations for most individuals. They are easy to swallow and free from gluten, soy, and dairy, making them suitable for those with dietary restrictions. I found this product effective for enhancing my overall health, improving my vision and immune function, and boosting my energy and focus. Given NOW Foods' reputation for quality, I highly recommend these softgels for anyone seeking a reliable source of vitamin A.

Bacterial Infection details

Essential for immunity

16 people found this helpful

Vitamin A is vital for immune function and lung health, especially during infections like those from viral illnesses. Recommended by Dr. Linus Pauling, I follow a regimen that includes multivitamins and large doses of vitamin A and C among others. The information available substantiates its importance in enhancing immunity.

Stabilised tumour markers

Brain Tumor details

7 people found this helpful

This may surprise you, but I was advised to take 225,000 IU of Vitamin A daily due to a positive cancer tumour marker. Now my numbers are down and stable. I also take 5,000 IU of Vitamin C and 10,000 IU of D, currently reduced to 3,000 IU. Despite concerns about overdose, I've managed well for over three years. My doctor suggests that high levels of vitamins A, C, and D in the body may prevent severe cases of corona or cancer. I believe the quality of NOW products is good.

Vitamin A supports immune response

Bronchitis details

Zhang L, Hou Y, Ma Z, Xie J, Fan J, et al. Effect of oral vitamin A supplementation on host immune response to infectious bronchitis virus infection in specific pathogen-free chicken. Poult Sci. 2023;102:102701. doi:10.1016/j.psj.2023.102701

We conducted a study to investigate how vitamin A supplementation affects the immune response in chickens infected with the infectious bronchitis virus (IBV). In our approach, we used 40 one-day-old specific pathogen-free (SPF) chickens, dividing them into two groups. One group received an oral vitamin A treatment daily, while the other group was given a placebo until they were 21 days old.

Afterward, both groups were infected with a pathogenic strain of IBV. Our findings showed that while vitamin A supplementation didn't significantly alter the disease's clinical course or the chickens' overall growth, it had some notable effects on their immune response. Specifically, we observed increased levels of IBV-specific antibodies and a decrease in viral load in certain tissues among the vitamin A group.

Interestingly, vitamin A appeared to also suppress some immune responses, leading to lower expression levels of certain molecules related to inflammation and immune regulation. While vitamin A helped improve specific aspects of the immune response, it did not completely cure the chickens or prevent infection.

Overall, we can conclude that while vitamin A supplementation can offer some benefits in terms of boosting immunity and managing viral replication, it doesn't drastically change the outcome of IBV infections in chickens.

Cough relief

Most Useful Review

4 people found this helpful

This product resolved my chronic cough of 20 years within days. I bought it for my husband after his bronchitis, and it worked wonders for both of us. By the second dose, I stopped coughing entirely, which is something I hadn’t experienced before. This is now a staple in my home.

Updated: Apr 2025

Cholecystitis details

Improved skin condition

I take it to bolster my immune system and to prevent stone formation in the gallbladder and kidneys. My skin has shown significant improvement. It suited me well, and I would certainly recommend it! The quality is excellent, the ingredients work effectively for me, and the size is appropriate. The dosage is adequate, and I have noticed tangible benefits. The taste is fine.

This supplement has been excellent for my mother, who was prescribed it as part of her menopause treatment. It’s a good addition to her needs.

Menopause details

A single dose completely cured my sinusitis!

Sinusitis details

Vitamin A's impact on OSA

Sleep Apnea details

Saruhan E, Sertoglu E, Unal Y, Bek S, Kutlu G. The role of antioxidant vitamins and selenium in patients with obstructive sleep apnea. Sleep Breath. 2021;25:923. doi:10.1007/s11325-020-02207-w

We conducted a case-control study to explore the levels of essential antioxidant nutrients, particularly vitamin A, in patients with obstructive sleep apnea (OSA) who did not have any other health issues. By categorizing our 146 subjects based on their apnea-hypopnea index (AHI) scores, we examined how these nutrient levels compared between those with mild to severe OSA and healthy individuals.

Our findings revealed that patients with OSA showed increased concentrations of vitamin A as part of their antioxidant response. This suggests that vitamin A and selenium may serve as important defenses against the harmful impacts of OSA. The implication of our research highlights that supplementing with antioxidant nutrients could be a beneficial approach to enhance overall health in individuals suffering from sleep apnea.

However, while there is a positive correlation between vitamin A levels and OSA, it is important to note that the isolated effects of vitamin A were not the primary focus of our study. Therefore, more research is needed to fully unravel its specific role in treating or managing sleep apnea.

7.5

Uncertain effects

Most Useful Review

I'm not sure yet, but I've been struggling to sleep well. I purchased it after reading reviews claiming it could help improve sleep quality.

Updated: Mar 2026

Ulcer details

Vitamin A protects against ulcers

Based on 18 Researches

von Gerstenbergk L, Büsing M, Seufert RM, Doertenbach J, Hottenrott C. [Lose-dose treatment with vitamin A in prevention of stress ulcer in swine]. Langenbecks Arch Chir. 1976;Suppl:224.

We focused on the protective effects of vitamin A on stress-induced gastric lesions in piglets after experiencing hemorrhagic shock. In our study, piglets were subjected to low blood pressure and then treated with different doses of vitamin A. Remarkably, those receiving vitamin A showed no signs of gastric lesions.

This suggests that vitamin A plays a significant role in safeguarding the gastric lining against stress-related damage during critical conditions.

Overall, our findings highlight the potential benefits of vitamin A in both veterinary and human medicine for ulcer prevention under stress.

Improvement observed

Most Useful Review

56 people found this helpful

The required dosage of vitamin A varies significantly between individuals, particularly for those with dry eyes, asthma, gastrointestinal issues, or a history of cancer. Due to my low protein intake, I've gradually increased my dosage to 100,000 units over a year. Remarkably, my persistent gastritis, unresolved for over ten years, has cleared, eliminating the need for medication.

Updated: Apr 2026

Blurred Vision details

Vitamin A treatment improves blurred vision

Based on 6 Researches

We investigated a case of persistent blurred vision following cataract surgery, leading to the discovery of vitamin A deficiency in a 74-year-old man. Using advanced tests like full-field electroretinograms and optical coherence tomography, we noted significant retinal changes and low vitamin A levels.

After administering vitamin A supplements for three months, we saw remarkable improvement in his vision and retinal health. This highlights the importance of diagnosing vitamin A deficiency, especially in patients showing persistent vision problems post-surgery.

Vision significantly improved

Most Useful Review

11 people found this helpful

Improved vision. After one month of taking this vitamin, my sight improved remarkably. I noticed that I wasn’t squinting anymore, and the dryness in my hands and eyes vanished. The capsules are small, odourless and tasteless. The brand’s quality is top-notch! I highly recommend it!

Updated: Mar 2026

Cancer details

Vitamin A aids ovarian cancer treatment

Based on 16 Researches

Mei B, Li J, Wang D, Feng L, Huang J, et al. All-trans Retinoic Acid Sensitizes Epithelial Ovarian Cancer to PARP Inhibition after Exposure to Cisplatin. Mol Cancer Ther. 2025;24:453. doi:10.1158/1535-7163.MCT-24-0140

We focused on how all-trans retinoic acid (ATRA), a form of vitamin A, helps combat resistance in epithelial ovarian cancer (EOC) when combined with standard platinum-based chemotherapy, such as cisplatin.

Our findings indicate that ATRA effectively reduced PARP inhibitor resistance in EOC cells, both in lab settings and in animal models.

Additionally, using ATRA along with ongoing treatment improved survival rates in EOC-bearing mice. This suggests that ATRA could be an important part of future therapies for enhancing the effectiveness of existing treatments.

Improved gastritis

Most Useful Review

56 people found this helpful

The required amount of Vitamin A varies significantly depending on individual circumstances. Those with dry eye, asthma, gastrointestinal issues, or a family history of cancer may require more. I gradually increased my intake to 100,000 units for a year, which cleared my persistent red sore gastritis, eliminating the need for medication.

Updated: Apr 2025

Celiac details

Improved vision clarity

The doctor prescribed this to improve our vision, and the quality is excellent. It is tasteless and gluten-free, egg-free, and GMO-free, which is essential. We've experienced better clarity and reduced fatigue, and the condition of our skin and hair has improved. This supplement suits adults, particularly teenagers who spend much time at computers. The tablets are small and the packaging is good. Delivery was fast, and we plan to reorder frequently.

It works well; I’ve noticed an effect, and my chronic fatigue syndrome has improved significantly.

Chronic Fatigue Syndrome details

Vitamin A supports airway function recovery

Common Cold details

Amaral CT, Pontes NN, Maciel BL, Bezerra HS, Triesta AN, et al. Vitamin A deficiency alters airway resistance in children with acute upper respiratory infection. Pediatr Pulmonol. 2013;48:481. doi:10.1002/ppul.22621

We examined the role of vitamin A in helping children recover from upper respiratory infections.

In our case control study involving children aged 4-6, we found that those with respiratory infections had lower vitamin A levels compared to healthy kids.

Surprisingly, while vitamin A seems to support airway function during recovery, children with wheezing did not show the same benefits.

Overall, vitamin A appears vital for maintaining healthy respiratory function, especially when kids are fighting off infections.

Clear skin achieved

Most Useful Review

I can't recall how many times I've purchased Vitamin A due to issues with pimples and my facial skin. I must say, it feels fantastic, and I no longer experience any pimples. This supplement has become essential for me.

Updated: Mar 2026

Diabetes details

3 people found this helpful

Great! Both my eyes and skin benefit from this. I find it very effective as my eyes no longer dry out after prolonged use. My night vision has improved too. I've had diabetes for over 10 years, leading to inevitable fundus damage. However, with regular use of this vitamin A, I've managed to delay and reduce such damage. My skin appears smoother, unlike someone in their 50s. Occasionally, after continuous use, my skin feels itchy due to the high dose of 25,000 units per capsule. At that point, a short break helps. My genetic test pointed to a vitamin A metabolic disorder, hence the higher dosage. If in doubt, I'd suggest the average person stick to 10,000 units.

Herpes details

Effective herpes relief

I took a large dosage just in case, and it proved useful almost immediately. Following COVID, I experienced an exacerbation of herpes, affecting my mucous membranes. By the third day of taking vitamin A at this dosage, I noticed improvements.

Acne details

Vitamin A's effectiveness in acne

Based on 17 Researches

Algarin YA, Pulumati A, Jaalouk D, Tan J, Nouri K. The role of vitamins and nutrients in rosacea. Arch Dermatol Res. 2024;316:142. doi:10.1007/s00403-024-02895-4

We explored how vitamin A can influence acne treatment, focusing on the effectiveness of its derivatives. According to the findings, oral isotretinoin, a form of vitamin A, showed remarkable efficacy. Patients experienced a significant reduction in lesions—up to 90%—with complete remission in one-quarter of those involved in the study.

Moreover, more than half of the participants reported substantial improvement after treatment. This strong performance suggests that vitamin A plays a key role in managing acne symptoms effectively.

Overall, the evidence we examined indicates that incorporating vitamin A, particularly through isotretinoin, can lead to significant improvements for individuals struggling with acne.

Improved skin health

Most Useful Review

305 people found this helpful

As a longtime acne sufferer, I've tried everything from Accutane to various skincare products without success. In just a week of using this supplement, I saw tremendous improvement; my skin appears clearer, my pores are smaller, and I'm even comfortable without makeup for the first time. The reduction in acne is phenomenal, with noticeable changes in texture and tone. For better absorption, I take it with a healthy fat like coconut oil, which I highly recommend.

Updated: Apr 2026

Lung Cancer details

Vitamin A mitigates lung cancer

Based on 9 Researches

Grace VMB, Wilson DD, Anushya R. Regulation of inflammation and COX-2 gene expression in benzo (a) pyrene induced lung carcinogenesis in mice by all trans retinoic acid (ATRA). Life Sci. 2021;285:119967. doi:10.1016/j.lfs.2021.119967

We aimed to understand how all-trans retinoic acid (ATRA), a form of vitamin A, influences lung cancer development caused by benzo(a)pyrene (B(a)P) exposure in mice. The study involved a thorough examination of the overall health of the mice, including body and organ weights, blood tests, and tissue analysis for any signs of damage or inflammation.

In our observations, B(a)P significantly harmed the mice, leading to weight loss and increased organ weight, particularly in the liver and lungs. Blood analysis revealed a concerning decrease in healthy blood cells and an increase in inflammatory markers, indicating an unhealthy state. However, we found that when these mice were treated with ATRA, their conditions improved remarkably.

The treated mice regained weight, saw improvements in their blood parameters, and exhibited lower levels of cancer-related inflammation. Notably, the expression of the COX-2 gene—an important player in inflammation and cancer—was dramatically reduced with ATRA treatment in both lung and liver tissues. This suggests that ATRA effectively counteracts the inflammatory effects and may help prevent the initial stages of cancer caused by B(a)P exposure.

Overall, our findings highlight the potential of vitamin A in mitigating some of the risks associated with lung cancer development due to environmental carcinogens, supporting further exploration of its role in cancer prevention.

Tumour markers normalised

Most Useful Review

13 people found this helpful

I have taken Vitamin A for five years as advised by my doctor to lower lung cancer marker levels. Initially, I took high doses but now manage with 75,000 IU daily, supporting my recovery and normalising my tumour markers.

Updated: Apr 2025

Autoimmune Disorder details

Vitamin A deficiency worsens lupus nephritis

Based on 16 Researches

Abdelhamid L, Alajoleen R, Kingsmore KM, Cabana-Puig X, Lu R, et al. Hypovitaminosis A Drives the Progression of Tubulointerstitial Lupus Nephritis through Potentiating Predisease Cellular Autoreactivity. Immunohorizons. 2023;7:17. doi:10.4049/immunohorizons.2200015

We examined the impact of vitamin A deficiency (VAD) on the progression of lupus nephritis in a mouse model. By inducing VAD during pregnancy or after weaning, we discovered that both methods significantly worsened the condition, leading to higher mortality rates.

Interestingly, restoring vitamin A levels after weaning reduced mortality. This suggests that VAD accelerates lupus nephritis through increased immune cell activation and autoantibody production. However, effects were less pronounced when VAD was introduced post-weaning. Overall, the study highlights the potential dangers of vitamin A deficiency in autoimmune diseases.

Skin problem relief

Most Useful Review

3 people found this helpful

I ordered this vitamin for a colleague with chronic skin issues who had seen no improvement with treatments from her dermatologist. After taking these vitamins with vitamin C and zinc, her skin has cleared up significantly. She's thrilled with the results.

Updated: Mar 2026

Headache details

Vitamin A toxicity's impact on headaches

Based on 3 Researches

Hajaj H, Ghanam A, Zahiri H, Babakhouya A, Rkain M. A Rare Case Report of Benign Intracranial Hypertension Caused by Hypervitaminosis A. Cureus. 2024;16:e59401. doi:10.7759/cureus.59401

We examined a rare case involving a 13-year-old girl who experienced symptoms of headache and visual disturbances due to benign intracranial hypertension (BIH) related to vitamin A toxicity. This condition was characterized by elevated pressure inside her skull, which led to her experiencing severe headaches, photophobia, and vomiting.

After conducting various tests, including magnetic resonance imaging and a lumbar puncture, we confirmed the diagnosis of BIH. Treatment was initiated with acetazolamide, a medication commonly used to reduce intracranial pressure. Although the study primarily focuses on the condition resulting from vitamin A excess, the use of acetazolamide makes it challenging to isolate the effect of vitamin A on headache relief specifically.

What's particularly noteworthy in this case is the significant elevation of serum vitamin A levels, which aligned with her symptoms. Following treatment, this patient showed a remarkable clinical improvement, including a reduction in papilledema during regular eye check-ups. Within just two weeks after starting treatment, she was discharged symptom-free, highlighting how important it is to consider vitamin A levels in children presenting with similar symptoms.

This case serves as a reminder for clinicians regarding the potential consequences of vitamin A toxicity, especially when evaluating children with headaches correlated to papilledema.

7.5

Quality vitamins noted

Most Useful Review

2 people found this helpful

I started taking this product for chronic headaches related to low cerebrospinal fluid. I advise against using it without a doctor’s supervision, as Vitamin A can build up to toxic levels. The product quality is good, arriving in a sealed bottle. Despite being fish liver derived, it has no fishy aftertaste. I will order this again.

Updated: Mar 2026

Pelvic Pain details

Effect of vitamin A on menstrual pain

Based on 2 Researches

USERS' SCORE

Good

Based on 4 Reviews

Sen LC, Jahan I, Salekin N, Shourove JH, Rahman M, et al. Food craving, vitamin A, and menstrual disorders: A comprehensive study on university female students. PLoS One. 2024;19:e0310995. doi:10.1371/journal.pone.0310995

We explored how dietary habits, specifically vitamin A intake, affect menstrual disorders like dysmenorrhea and irregular menstrual cycles among female university students in Bangladesh.

Our findings suggest that students consuming more vitamin A-rich plant foods are significantly less likely to experience these painful conditions. In fact, those who increased their intake had a 40% lower risk of dysmenorrhea and a 60% lower risk of an irregular menstrual cycle.

We also noticed that high fat and sweet food cravings heightened the likelihood of these issues, prompting us to recommend better dietary choices and regular exercise for improved health.

Tingling sensation gone

Most Useful Review

2 people found this helpful

I started taking one tablet each morning and evening for a week, and now just one in the morning. Previously, I'd felt tingling and pain while trying to focus, but that sensation has now vanished. I hope this isn't just my imagination; if this improvement holds, I'd be extremely grateful if it turns out that vitamin A deficiency was the cause.

Updated: Mar 2026

Bone Pain details

High vitamin A causes bone pain

Based on 2 Researches

Baineni R, Gulati R, Delhi CK. Vitamin A toxicity presenting as bone pain. Arch Dis Child. 2017;102:556. doi:10.1136/archdischild-2016-310631

We examined a case of a 4-year-old boy who experienced severe bone pain and related symptoms after taking high doses of vitamin A for three months. Despite typical liver-related complications usually associated with vitamin A toxicity, he presented with significant musculoskeletal issues and skin changes. Following the discontinuation of vitamin A, the boy showed a remarkable recovery within two months. This case highlights that excessive vitamin A intake can lead to serious bone pain and other health problems, though he did not develop liver disease as expected.

Effective for bone pain

Most Useful Review

7 people found this helpful

I purchased this hoping to enhance my vision and improve my mucous membranes. Surprisingly, it was remarkably effective against my bone pain associated with hernias. After starting it, my back pain resolved in just four days. When I resumed taking it after a minor back injury, it worked instantly. I feel the combination with B vitamins has a positive effect, and while I'm unsure about my eyesight, my skin appears clearer.

Updated: Apr 2025

Conjunctivitis details

Vitamin A reduces conjunctivitis rates

Haidar J, Tsegaye D, Mariam DH, Tibeb HN, Muroki NM. Vitamin A supplementation on child morbidity. East Afr Med J. 2003;80:17.

We conducted an interventional study to assess how vitamin A supplementation affects children's health, focusing on conditions like conjunctivitis. In Northern Ethiopia, nearly 4,800 children were monitored for symptoms and nutritional status before and after vitamin A capsules were distributed.

The results were promising—there was a notable decrease in conjunctivitis cases from 10.2% to just 3%. Additionally, improvements were seen in various other health indicators. However, while the findings are encouraging, they emphasize the need for ongoing education alongside vitamin A distribution.

Faster recovery noted

Most Useful Review

2 people found this helpful

Recently, popular antibacterial deodorants irritated my eyes. Upon examination by an ophthalmologist, I learned my cornea was damaged due to severe dry eye and allergic conjunctivitis. I was prescribed steroid eye drops and dry eye drops, but I believed I could manage it myself and opted for vitamin A. I feel that my recovery has been quicker than before.

Updated: Mar 2026

Eye Infection details

I have discovered that taking Vitamin A is an excellent preventive for Blepharitis, which I used to suffer from frequently. Regular use of this product has stopped the recurrences.

Heart Disease details

Vitamin A modulates heart repair

Based on 7 Researches

Rettkowski J, Romero-Mulero MC, Singh I, Wadle C, Wrobel J, et al. Modulation of bone marrow haematopoietic stem cell activity as a therapeutic strategy after myocardial infarction: a preclinical study. Nat Cell Biol. 2025;27:591. doi:10.1038/s41556-025-01639-4

We investigated the impact of vitamin A in treating heart disease, specifically after a myocardial infarction (MI). Our study focused on over 150 cardiac surgery patients, with a particular emphasis on the effects of vitamin A on bone marrow stem cells. We discovered that MI led to harmful changes in these stem cells and that vitamin A, specifically its metabolite 4-oxo-retinoic acid, helps reduce inflammation by calming the stem cells. This approach could improve heart function in the long run after an MI.

Effective recovery

Most Useful Review

An excellent choice. The main thing is to overcome the disease, and this has greatly helped in my recovery.

Updated: Mar 2026

Back Pain details

Vision clarity restored

After excessive computer and phone use, my vision noticeably declined. However, following the introduction of vitamin A into my routine, my clarity has significantly improved. I wholeheartedly recommend it.

Cold details

Vitamin A's key role in thermogenesis

Likely Very Effective

Fenzl A, Kulterer OC, Spirk K, Mitulović G, Marculescu R, et al. Intact vitamin A transport is critical for cold-mediated adipose tissue browning and thermogenesis. Mol Metab. 2020;42:101088. doi:10.1016/j.molmet.2020.101088

We explored how vitamin A affects our body’s response to cold, specifically looking at its role in transforming white fat into brown fat, a process known as browning. This transformation is significant, as it can help reduce obesity and improve metabolic health.

In our investigation, we conducted cold exposure studies involving both mice and humans. We observed that exposure to cold led to an increase in circulating vitamin A, also known as retinol, and its transporter protein, Rbp. However, in mice lacking this protein, we found that their ability to adapt to the cold and promote thermogenesis—essentially, generating heat through fat—was severely compromised.

Interestingly, we also noted that stimulating human fat cells with retinol heightened the expression of genes associated with thermogenesis and boosted mitochondrial activity, which is vital for burning fat. In humans, the rise in vitamin A during cold exposure hinted at improved fat utilization.

Overall, our findings revealed that not only are vitamin A levels responsive to cold, but effective transportation of this vitamin is crucial for cold-induced fat browning and the body's ability to generate heat.

Very effective during cold

Most Useful Review

11 people found this helpful

Good vitamin A that works very well during colds. It’s important to drink it together with D3 and C.

Updated: Mar 2026

High Cholesterol details

Vitamin A reduces cholesterol plaques

Based on 5 Researches

Zarei L, Bahrami M, Farhad N, Froushani SMA, Abbasi A. All-trans retinoic acid effectively reduces atheroma plaque size in a rabbit model of high-fat-induced atherosclerosis. Adv Clin Exp Med. 2018;27:1631. doi:10.17219/acem/74552

We explored the effects of all-trans retinoic acid (atRA) on atherosclerosis in rabbits fed a high-fat diet. In an experiment where rabbits were divided into groups, some received atRA while others received atorvastatin or both.

We found that atRA effectively reduced plaque size, comparable to atorvastatin, and their combination was even more effective. Additionally, atRA improved the serum lipid profile, suggesting it could be a valuable tool in managing cholesterol levels.

7.5

Asthenopia noticeably improved

Most Useful Review

7 people found this helpful

I started with two capsules (50,000 IU) daily from 10,000 IU, and my asthenopia has improved considerably. This high-protein diet allows me to spend my days comfortably without experiencing adverse effects.

Updated: Mar 2026

Athlete’s Foot details

Effective for dryness

A great help! I have ordered this multiple times and consistently see the results! The dry skin on my hands, feet, and heels has improved considerably.

Excellent product. Very small ball. I take it once a day during flu.

Flu details

Dramatic improvement noted

Adenoiditis details

My elderly mother frequently coughed and had a rough throat, but since starting this supplement, she has shown a remarkable improvement in her mucous membrane health. It's been a genuinely beneficial supplement for her condition.

5 people found this helpful

Liver Disease details

Initially, I took vitamin A with cod liver oil for dry eye and night blindness, but switched to a more potent supplement, significantly improving my vision, even if my eye conditions remained unchanged. This has become a crucial addition to my regimen, supporting liver health.