Last update
3/26/2026
Reviewed By
Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 6 Researches
7.6
USERS' SCORE
Good
Based on 4 Reviews
8.4
Supplement Facts
Serving Size: 1 Softgel
Amount Per Serving
%DV
Vitamin A (from Retinyl Palmitate and Fish Liver Oil)
7,500 mcg
833%
Top Medical Research Studies
9
We explored the impact of the oral aromatic retinoid, Ro 10-9359, on common warts caused by human papilloma virus (HPV) 2 in a patient with chronic lymphatic leukemia.
The treatment led to rapid improvement, with no detectable viral particles or DNA during the therapy. However, the treatment had to stop due to the patient's development of a liposarcoma, leading to a relapse of the warts.
Notably, the same HPV-2 subtype was present before and after the treatment, suggesting limited long-term effectiveness.
The treatment led to rapid improvement, with no detectable viral particles or DNA during the therapy. However, the treatment had to stop due to the patient's development of a liposarcoma, leading to a relapse of the warts.
Notably, the same HPV-2 subtype was present before and after the treatment, suggesting limited long-term effectiveness.
Read More
7
We explored the effectiveness of a retinoic acid derivative, Ro 10-9359, for treating warts, particularly in patients who struggled to walk due to extensive verrucae plantares. While two patients experienced significant recovery, a larger group of 12 with verrucae vulgares showed disappointing results. We gradually increased the dosage to over 1.5 mg/kg, monitoring for side effects, which were notable but manageable. Overall, Ro 10-9359 may be beneficial for stubborn plantar warts, especially when standard treatments fail, but the results vary significantly among patients.
Read More
4
Limited efficacy of vitamin A
We examined how effective a topical ointment containing 2% vitamin A acid is for treating plantar warts in a group of 50 patients. Over a treatment period of 2 to 10 weeks, only 17 patients showed signs of being cured.
This indicates that while there may be some benefit to using vitamin A for warts, the results are not overwhelmingly positive.
This indicates that while there may be some benefit to using vitamin A for warts, the results are not overwhelmingly positive.
Read More
Most Useful Reviews
9
Warts disappeared
47 people found this helpful
I have experienced significant dryness in my nose and throat for the past two years, alongside an uncomfortable feeling in my eyes and a wrinkled wart. Initially, I believed the dryness in my nose was due to winter humidity. I encountered nasal discharge mixed with blood, despite not having a blocked nose, and was diagnosed with Graves’ disease and hay fever. In my attempt to combat inflammation, I used cortisol, which worsened my condition. Eventually, I began taking vitamin A, which led to a noticeable improvement. To my surprise, the wart contracted and vanished, my dry skin ceased, and my nasal mucosa felt less irritated. Remarkably, my menstrual bleeding diminished. I feel vitamin A is crucial for addressing various health issues, including the depletion linked to my condition.
Read More
7
Warts disappeared
40 people found this helpful
Since fat-soluble vitamins accumulate, one must avoid overdose. However, there are substantial individual differences, with variations of up to 10 to 13 times between cancer and non-cancer families. Those with mucosal inflammation, such as dry eye, rhinitis, and sinusitis, may require higher concentrations. Even substantial doses don’t lead to excessive symptoms; rather, many conditions improve. For dry heels, taking two tablets daily notably improves the condition within a week. Strong cracks benefit significantly from biotin. Recovering may take time for diabetics. Additionally, Warts and anal fissures typically resolve within 2 to 3 months. These vitamins can also aid in height growth for children and are essential for those with fair skin and moles.
Read More
9
Warts disappeared
6 people found this helpful
Effective for warts! I purchased this after reading multiple reviews online regarding the use of topical vitamin A for warts. I can happily say that it is quite effective on warts; they have not only shrunk but have completely disappeared after applying this daily for a couple of weeks. The size of the capsules is larger than the 10K IU ones, but the ingredients are the same high-quality fish oil.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 6 Researches
7.6
- All Researches
9.5
Topical vitamin A shows promise
We explored the use of topical vitamin A in treating stubborn common warts. In a case study, a healthy 30-year-old woman with a long history of persistent warts tried multiple treatments without success.
After applying natural vitamin A from fish liver oil daily, most warts cleared up in about 70 days, while a larger wart took up to six months to resolve.
While this case suggests potential benefits, further controlled studies are needed to better understand vitamin A’s effectiveness against common warts and other related skin issues.
After applying natural vitamin A from fish liver oil daily, most warts cleared up in about 70 days, while a larger wart took up to six months to resolve.
While this case suggests potential benefits, further controlled studies are needed to better understand vitamin A’s effectiveness against common warts and other related skin issues.
Read More
9
We explored the combined effect of topical Tretinoin, a vitamin A derivative, with Superficial X-ray therapy (SXRT) in treating periungual warts (PWs). In this study, we observed 65 PWs, divided into two groups. One group received only SXRT, while the other group received SXRT along with Tretinoin cream from the very beginning.
Our findings indicated that the combination treatment with Tretinoin significantly enhanced the clearance rate of the warts compared to SXRT alone. Specifically, 92.7% of the PWs in the combined treatment group cleared completely within the study period, compared to just 75% in the SXRT group. Additionally, the time it took for the warts to heal was shorter with the combined treatment—16 days compared to 19.9 days for SXRT alone.
We also found that there were no severe side effects, and the minor effects reported were manageable. This suggests that using topical Tretinoin with SXRT is not only effective but also safe, making it an appealing option for those seeking a non-invasive treatment for PWs.
Our findings indicated that the combination treatment with Tretinoin significantly enhanced the clearance rate of the warts compared to SXRT alone. Specifically, 92.7% of the PWs in the combined treatment group cleared completely within the study period, compared to just 75% in the SXRT group. Additionally, the time it took for the warts to heal was shorter with the combined treatment—16 days compared to 19.9 days for SXRT alone.
We also found that there were no severe side effects, and the minor effects reported were manageable. This suggests that using topical Tretinoin with SXRT is not only effective but also safe, making it an appealing option for those seeking a non-invasive treatment for PWs.
Read More
9
We explored the impact of the oral aromatic retinoid, Ro 10-9359, on common warts caused by human papilloma virus (HPV) 2 in a patient with chronic lymphatic leukemia.
The treatment led to rapid improvement, with no detectable viral particles or DNA during the therapy. However, the treatment had to stop due to the patient's development of a liposarcoma, leading to a relapse of the warts.
Notably, the same HPV-2 subtype was present before and after the treatment, suggesting limited long-term effectiveness.
The treatment led to rapid improvement, with no detectable viral particles or DNA during the therapy. However, the treatment had to stop due to the patient's development of a liposarcoma, leading to a relapse of the warts.
Notably, the same HPV-2 subtype was present before and after the treatment, suggesting limited long-term effectiveness.
Read More
7
We conducted a case-control study to investigate the link between retinol-binding protein (RBP) levels and resistant warts, which are warts that don’t respond to conventional treatments. Our research included 30 patients with such warts and 30 matched healthy controls, allowing us to measure serum levels of RBP through a method called ELISA.
From our findings, we observed a significant difference in serum RBP levels between the two groups, suggesting a connection between low RBP and the development of stubborn warts. RBP plays a crucial role in the metabolism of vitamin A, and a deficiency may hinder the body’s ability to fight off the viral factors involved in wart formation.
Despite the results indicating low serum RBP levels in patients with resistant warts, the study did not establish a direct treatment effect of vitamin A on warts. While low RBP levels might highlight a possible pathway in wart persistence, further research is needed to confirm if increasing vitamin A could effectively treat these stubborn skin issues.
From our findings, we observed a significant difference in serum RBP levels between the two groups, suggesting a connection between low RBP and the development of stubborn warts. RBP plays a crucial role in the metabolism of vitamin A, and a deficiency may hinder the body’s ability to fight off the viral factors involved in wart formation.
Despite the results indicating low serum RBP levels in patients with resistant warts, the study did not establish a direct treatment effect of vitamin A on warts. While low RBP levels might highlight a possible pathway in wart persistence, further research is needed to confirm if increasing vitamin A could effectively treat these stubborn skin issues.
Read More
7
We explored the effectiveness of a retinoic acid derivative, Ro 10-9359, for treating warts, particularly in patients who struggled to walk due to extensive verrucae plantares. While two patients experienced significant recovery, a larger group of 12 with verrucae vulgares showed disappointing results. We gradually increased the dosage to over 1.5 mg/kg, monitoring for side effects, which were notable but manageable. Overall, Ro 10-9359 may be beneficial for stubborn plantar warts, especially when standard treatments fail, but the results vary significantly among patients.
Read More
User Reviews
USERS' SCORE
Good
Based on 4 Reviews
8.4
- All Reviews
- Positive Reviews
- Negative Reviews
9
Warts disappeared
47 people found this helpful
I have experienced significant dryness in my nose and throat for the past two years, alongside an uncomfortable feeling in my eyes and a wrinkled wart. Initially, I believed the dryness in my nose was due to winter humidity. I encountered nasal discharge mixed with blood, despite not having a blocked nose, and was diagnosed with Graves’ disease and hay fever. In my attempt to combat inflammation, I used cortisol, which worsened my condition. Eventually, I began taking vitamin A, which led to a noticeable improvement. To my surprise, the wart contracted and vanished, my dry skin ceased, and my nasal mucosa felt less irritated. Remarkably, my menstrual bleeding diminished. I feel vitamin A is crucial for addressing various health issues, including the depletion linked to my condition.
Read More
7
Warts disappeared
40 people found this helpful
Since fat-soluble vitamins accumulate, one must avoid overdose. However, there are substantial individual differences, with variations of up to 10 to 13 times between cancer and non-cancer families. Those with mucosal inflammation, such as dry eye, rhinitis, and sinusitis, may require higher concentrations. Even substantial doses don’t lead to excessive symptoms; rather, many conditions improve. For dry heels, taking two tablets daily notably improves the condition within a week. Strong cracks benefit significantly from biotin. Recovering may take time for diabetics. Additionally, Warts and anal fissures typically resolve within 2 to 3 months. These vitamins can also aid in height growth for children and are essential for those with fair skin and moles.
Read More
9
Warts disappeared
6 people found this helpful
Effective for warts! I purchased this after reading multiple reviews online regarding the use of topical vitamin A for warts. I can happily say that it is quite effective on warts; they have not only shrunk but have completely disappeared after applying this daily for a couple of weeks. The size of the capsules is larger than the 10K IU ones, but the ingredients are the same high-quality fish oil.
Read More
7
Slow wart removal
I have used vitamin A for removing small Warts on my hands by piercing the capsule and applying the liquid directly. After several months of consistent application, I found it works gradually, though the fishy smell is rather off-putting.
Read More
Frequently Asked Questions
No FAQs are available for this product and symptom.
References
- Xu J, Zhang D, Feng L, Liu Y, Diao Q. The efficacy and safety of topical Tretinoin combined with superficial X-ray therapy (SXRT) in treating periungual warts. Dermatol Ther. 2022;35:e15295. 10.1111/dth.15295
- Khalid HN, Abd El Gayed EM, Dawoud RA, Bazid HAS. Measuring the serum level of retinol-binding protein can enhance the treatment of recalcitrant warts. J Cosmet Dermatol. 2021;20:1031. 10.1111/jocd.13683
- Gaston A, Garry RF. Topical vitamin A treatment of recalcitrant common warts. Virol J. 2012;9:21. 10.1186/1743-422X-9-21
- Gross G, Pfister H, Hagedorn M, Stahn R. Effect of oral aromatic retinoid (Ro 10-9359) on human papilloma virus-2-induced common warts. Dermatologica. 1983;166:48. PubMed
- Rüst O, Rufli T, Forrer J. [First experience with retinoid acid derivative Ro 10-9359 in the treatment of viral epithelioma]. Schweiz Med Wochenschr. 1979;109:1914. PubMed
- de Bersaques J. Vitamin A acid in the topic treament of plantar warts. Dermatologica. 1975;150:369. PubMed
Data last updated:
